Health-LLM: Personalized Retrieval-Augmented Disease Prediction Model

Artificial intelligence (AI) in healthcare has significantly advanced intelligent medical treatment. However, traditional intelligent healthcare is limited by static data and unified standards, preventing full integration with individual situations and other challenges. Hence, a more professional and detailed intelligent healthcare method is needed for development. To this end, we propose an innovative framework named Heath-LLM, which combines large-scale feature extraction and medical knowledge trade-off scoring. Compared to traditional health management methods, our approach has three main advantages. First, our method integrates health reports into a large model to provide detailed task information. Second, professional medical expertise is used to adjust the weighted scores of health characteristics. Third, we use a semi-automated feature extraction framework to enhance the analytical power of language models and incorporate expert insights to improve the accuracy of disease prediction. We have conducted disease prediction experiments on a large number of health reports to assess the effectiveness of Health-LLM. The results of the experiments indicate that the proposed method surpasses traditional methods and has the potential to revolutionize disease prediction and personalized health management. The code is available at https://github.com/jmyissb/HealthLLM.

Explaining Time Series via Contrastive and Locally Sparse Perturbations

Explaining multivariate time series is a compound challenge, as it requires identifying important locations in the time series and matching complex temporal patterns. Although previous saliency-based methods addressed the challenges, their perturbation may not alleviate the distribution shift issue, which is inevitable especially in heterogeneous samples. We present ContraLSP, a locally sparse model that introduces counterfactual samples to build uninformative perturbations but keeps distribution using contrastive learning. Furthermore, we incorporate sample-specific sparse gates to generate more binary-skewed and smooth masks, which easily integrate temporal trends and select the salient features parsimoniously. Empirical studies on both synthetic and real-world datasets show that ContraLSP outperforms state-of-the-art models, demonstrating a substantial improvement in explanation quality for time series data. The source code is available at \url{https://github.com/zichuan-liu/ContraLSP}.

DataFrame QA: A Universal LLM Framework on DataFrame Question Answering Without Data Exposure

This paper introduces DataFrame question answering (QA), a novel task that utilizes large language models (LLMs) to generate Pandas queries for information retrieval and data analysis on dataframes, emphasizing safe and non-revealing data handling. Our method, which solely relies on dataframe column names, not only ensures data privacy but also significantly reduces the context window in the prompt, streamlining information processing and addressing major challenges in LLM-based data analysis. We propose DataFrame QA as a comprehensive framework that includes safe Pandas query generation and code execution. Various LLMs, notably GPT-4, are evaluated using the pass@1 metric on the renowned WikiSQL and our newly developed 'UCI-DataFrameQA', tailored for complex data analysis queries. Our findings indicate that GPT-4 achieves pass@1 rates of 86% on WikiSQL and 97% on UCI-DataFrameQA, underscoring its capability in securely retrieving and aggregating dataframe values and conducting sophisticated data analyses. This approach, deployable in a zero-shot manner without prior training or adjustments, proves to be highly adaptable and secure for diverse applications.

The Impact of Reasoning Step Length on Large Language Models

Chain of Thought (CoT) is significant in improving the reasoning abilities of large language models (LLMs). However, the correlation between the effectiveness of CoT and the length of reasoning steps in prompts remains largely unknown. To shed light on this, we have conducted several empirical experiments to explore the relations. Specifically, we design experiments that expand and compress the rationale reasoning steps within CoT demonstrations, while keeping all other factors constant. We have the following key findings. First, the results indicate that lengthening the reasoning steps in prompts, even without adding new information into the prompt, considerably enhances LLMs' reasoning abilities across multiple datasets. Alternatively, shortening the reasoning steps, even while preserving the key information, significantly diminishes the reasoning abilities of models. This finding highlights the importance of the number of steps in CoT prompts and provides practical guidance to make better use of LLMs' potential in complex problem-solving scenarios. Second, we also investigated the relationship between the performance of CoT and the rationales used in demonstrations. Surprisingly, the result shows that even incorrect rationales can yield favorable outcomes if they maintain the requisite length of inference. Third, we observed that the advantages of increasing reasoning steps are task-dependent: simpler tasks require fewer steps, whereas complex tasks gain significantly from longer inference sequences.

Explanations of Classifiers Enhance Medical Image Segmentation via End-to-end Pre-training

Medical image segmentation aims to identify and locate abnormal structures in medical images, such as chest radiographs, using deep neural networks. These networks require a large number of annotated images with fine-grained masks for the regions of interest, making pre-training strategies based on classification datasets essential for sample efficiency. Based on a large-scale medical image classification dataset, our work collects explanations from well-trained classifiers to generate pseudo labels of segmentation tasks. Specifically, we offer a case study on chest radiographs and train image classifiers on the CheXpert dataset to identify 14 pathological observations in radiology. We then use Integrated Gradients (IG) method to distill and boost the explanations obtained from the classifiers, generating massive diagnosis-oriented localization labels (DoLL). These DoLL-annotated images are used for pre-training the model before fine-tuning it for downstream segmentation tasks, including COVID-19 infectious areas, lungs, heart, and clavicles. Our method outperforms other baselines, showcasing significant advantages in model performance and training efficiency across various segmentation settings.

Towards Explainable Artificial Intelligence (XAI): A Data Mining Perspective

Given the complexity and lack of transparency in deep neural networks (DNNs), extensive efforts have been made to make these systems more interpretable or explain their behaviors in accessible terms. Unlike most reviews, which focus on algorithmic and model-centric perspectives, this work takes a "data-centric" view, examining how data collection, processing, and analysis contribute to explainable AI (XAI). We categorize existing work into three categories subject to their purposes: interpretations of deep models, referring to feature attributions and reasoning processes that correlate data points with model outputs; influences of training data, examining the impact of training data nuances, such as data valuation and sample anomalies, on decision-making processes; and insights of domain knowledge, discovering latent patterns and fostering new knowledge from data and models to advance social values and scientific discovery. Specifically, we distill XAI methodologies into data mining operations on training and testing data across modalities, such as images, text, and tabular data, as well as on training logs, checkpoints, models and other DNN behavior descriptors. In this way, our study offers a comprehensive, data-centric examination of XAI from a lens of data mining methods and applications.

LETA: Learning Transferable Attribution for Generic Vision Explainer

Explainable machine learning significantly improves the transparency of deep neural networks~(DNN). However, existing work is constrained to explaining the behavior of individual model predictions, and lacks the ability to transfer the explanation across various models and tasks. This limitation results in explaining various tasks being time- and resource-consuming. To address this problem, we develop a pre-trained, DNN-based, generic explainer on large-scale image datasets, and leverage its transferability to explain various vision models for downstream tasks. In particular, the pre-training of generic explainer focuses on LEarning Transferable Attribution (LETA). The transferable attribution takes advantage of the versatile output of the target backbone encoders to comprehensively encode the essential attribution for explaining various downstream tasks. LETA guides the pre-training of the generic explainer towards the transferable attribution, and introduces a rule-based adaptation of the transferable attribution for explaining downstream tasks, without the need for additional training on downstream data. Theoretical analysis demonstrates that the pre-training of LETA enables minimizing the explanation error bound aligned with the conditional $\mathcal{V}$-information on downstream tasks. Empirical studies involve explaining three different architectures of vision models across three diverse downstream datasets. The experiment results indicate LETA is effective in explaining these tasks without the need for additional training on the data of downstream tasks.

A Theoretical Approach to Characterize the Accuracy-Fairness Trade-off Pareto Frontier

While the accuracy-fairness trade-off has been frequently observed in the literature of fair machine learning, rigorous theoretical analyses have been scarce. To demystify this long-standing challenge, this work seeks to develop a theoretical framework by characterizing the shape of the accuracy-fairness trade-off Pareto frontier (FairFrontier), determined by a set of all optimal Pareto classifiers that no other classifiers can dominate. Specifically, we first demonstrate the existence of the trade-off in real-world scenarios and then propose four potential categories to characterize the important properties of the accuracy-fairness Pareto frontier. For each category, we identify the necessary conditions that lead to corresponding trade-offs. Experimental results on synthetic data suggest insightful findings of the proposed framework: (1) When sensitive attributes can be fully interpreted by non-sensitive attributes, FairFrontier is mostly continuous. (2) Accuracy can suffer a \textit{sharp} decline when over-pursuing fairness. (3) Eliminate the trade-off via a two-step streamlined approach. The proposed research enables an in-depth understanding of the accuracy-fairness trade-off, pushing current fair machine-learning research to a new frontier.

Boosting Fair Classifier Generalization through Adaptive Priority Reweighing

With the increasing penetration of machine learning applications in critical decision-making areas, calls for algorithmic fairness are more prominent. Although there have been various modalities to improve algorithmic fairness through learning with fairness constraints, their performance does not generalize well in the test set. A performance-promising fair algorithm with better generalizability is needed. This paper proposes a novel adaptive reweighing method to eliminate the impact of the distribution shifts between training and test data on model generalizability. Most previous reweighing methods propose to assign a unified weight for each (sub)group. Rather, our method granularly models the distance from the sample predictions to the decision boundary. Our adaptive reweighing method prioritizes samples closer to the decision boundary and assigns a higher weight to improve the generalizability of fair classifiers. Extensive experiments are performed to validate the generalizability of our adaptive priority reweighing method for accuracy and fairness measures (i.e., equal opportunity, equalized odds, and demographic parity) in tabular benchmarks. We also highlight the performance of our method in improving the fairness of language and vision models. The code is available at https://github.com/che2198/APW.