Remixing Functionally Graded Structures: Data-Driven Topology Optimization with Multiclass Shape Blending

To create heterogeneous, multiscale structures with unprecedented functionalities, recent topology optimization approaches design either fully aperiodic systems or functionally graded structures, which compete in terms of design freedom and efficiency. We propose to inherit the advantages of both through a data-driven framework for multiclass functionally graded structures that mixes several families, i.e., classes, of microstructure topologies to create spatially-varying designs with guaranteed feasibility. The key is a new multiclass shape blending scheme that generates smoothly graded microstructures without requiring compatible classes or connectivity and feasibility constraints. Moreover, it transforms the microscale problem into an efficient, low-dimensional one without confining the design to predefined shapes. Compliance and shape matching examples using common truss geometries and diversity-based freeform topologies demonstrate the versatility of our framework, while studies on the effect of the number and diversity of classes illustrate the effectiveness. The generality of the proposed methods supports future extensions beyond the linear applications presented.

Breaking the Moments Condition Barrier: No-Regret Algorithm for Bandits with Super Heavy-Tailed Payoffs

Despite a large amount of effort in dealing with heavy-tailed error in machine learning, little is known when moments of the error can become non-existential: the random noise $\eta$ satisfies Pr$\left[|\eta| > |y|\right] \le 1/|y|^{\alpha}$ for some $\alpha > 0$. We make the first attempt to actively handle such super heavy-tailed noise in bandit learning problems: We propose a novel robust statistical estimator, mean of medians, which estimates a random variable by computing the empirical mean of a sequence of empirical medians. We then present a generic reductionist algorithmic framework for solving bandit learning problems (including multi-armed and linear bandit problem): the mean of medians estimator can be applied to nearly any bandit learning algorithm as a black-box filtering for its reward signals and obtain similar regret bound as if the reward is sub-Gaussian. We show that the regret bound is near-optimal even with very heavy-tailed noise. We also empirically demonstrate the effectiveness of the proposed algorithm, which further corroborates our theoretical results.

Non-convex Distributionally Robust Optimization: Non-asymptotic Analysis

Distributionally robust optimization (DRO) is a widely-used approach to learn models that are robust against distribution shift. Compared with the standard optimization setting, the objective function in DRO is more difficult to optimize, and most of the existing theoretical results make strong assumptions on the loss function. In this work we bridge the gap by studying DRO algorithms for general smooth non-convex losses. By carefully exploiting the specific form of the DRO objective, we are able to provide non-asymptotic convergence guarantees even though the objective function is possibly non-convex, non-smooth and has unbounded gradient noise. In particular, we prove that a special algorithm called the mini-batch normalized gradient descent with momentum, can find an $\epsilon$ first-order stationary point within $O( \epsilon^{-4} )$ gradient complexity. We also discuss the conditional value-at-risk (CVaR) setting, where we propose a penalized DRO objective based on a smoothed version of the CVaR that allows us to obtain a similar convergence guarantee. We finally verify our theoretical results in a number of tasks and find that the proposed algorithm can consistently achieve prominent acceleration.

An Open Natural Language Processing Development Framework for EHR-based Clinical Research: A case demonstration using the National COVID Cohort Collaborative (N3C)

While we pay attention to the latest advances in clinical natural language processing (NLP), we can notice some resistance in the clinical and translational research community to adopt NLP models due to limited transparency, Interpretability and usability. Built upon our previous work, in this study, we proposed an open natural language processing development framework and evaluated it through the implementation of NLP algorithms for the National COVID Cohort Collaborative (N3C). Based on the interests in information extraction from COVID-19 related clinical notes, our work includes 1) an open data annotation process using COVID-19 signs and symptoms as the use case, 2) a community-driven ruleset composing platform, and 3) a synthetic text data generation workflow to generate texts for information extraction tasks without involving human subjects. The generated corpora derived out of the texts from multiple intuitions and gold standard annotation are tested on a single institution's rule set has the performances in F1 score of 0.876, 0.706 and 0.694, respectively. The study as a consortium effort of the N3C NLP subgroup demonstrates the feasibility of creating a federated NLP algorithm development and benchmarking platform to enhance multi-institution clinical NLP study.

Boosting the Certified Robustness of L-infinity Distance Nets

Recently, Zhang et al. (2021) developed a new neural network architecture based on $\ell_\infty$-distance functions, which naturally possesses certified robustness by its construction. Despite the excellent theoretical properties, the model so far can only achieve comparable performance to conventional networks. In this paper, we significantly boost the certified robustness of $\ell_\infty$-distance nets through a careful analysis of its training process. In particular, we show the $\ell_p$-relaxation, a crucial way to overcome the non-smoothness of the model, leads to an unexpected large Lipschitz constant at the early training stage. This makes the optimization insufficient using hinge loss and produces sub-optimal solutions. Given these findings, we propose a simple approach to address the issues above by using a novel objective function that combines a scaled cross-entropy loss with clipped hinge loss. Our experiments show that using the proposed training strategy, the certified accuracy of $\ell_\infty$-distance net can be dramatically improved from 33.30% to 40.06% on CIFAR-10 ($\epsilon=8/255$), meanwhile significantly outperforming other approaches in this area. Such a result clearly demonstrates the effectiveness and potential of $\ell_\infty$-distance net for certified robustness.

Semi-Supervised Semantic Segmentation via Adaptive Equalization Learning

Due to the limited and even imbalanced data, semi-supervised semantic segmentation tends to have poor performance on some certain categories, e.g., tailed categories in Cityscapes dataset which exhibits a long-tailed label distribution. Existing approaches almost all neglect this problem, and treat categories equally. Some popular approaches such as consistency regularization or pseudo-labeling may even harm the learning of under-performing categories, that the predictions or pseudo labels of these categories could be too inaccurate to guide the learning on the unlabeled data. In this paper, we look into this problem, and propose a novel framework for semi-supervised semantic segmentation, named adaptive equalization learning (AEL). AEL adaptively balances the training of well and badly performed categories, with a confidence bank to dynamically track category-wise performance during training. The confidence bank is leveraged as an indicator to tilt training towards under-performing categories, instantiated in three strategies: 1) adaptive Copy-Paste and CutMix data augmentation approaches which give more chance for under-performing categories to be copied or cut; 2) an adaptive data sampling approach to encourage pixels from under-performing category to be sampled; 3) a simple yet effective re-weighting method to alleviate the training noise raised by pseudo-labeling. Experimentally, AEL outperforms the state-of-the-art methods by a large margin on the Cityscapes and Pascal VOC benchmarks under various data partition protocols. Code is available at https://github.com/hzhupku/SemiSeg-AEL

Near-Optimal Reward-Free Exploration for Linear Mixture MDPs with Plug-in Solver

Although model-based reinforcement learning (RL) approaches are considered more sample efficient, existing algorithms are usually relying on sophisticated planning algorithm to couple tightly with the model-learning procedure. Hence the learned models may lack the ability of being re-used with more specialized planners. In this paper we address this issue and provide approaches to learn an RL model efficiently without the guidance of a reward signal. In particular, we take a plug-in solver approach, where we focus on learning a model in the exploration phase and demand that \emph{any planning algorithm} on the learned model can give a near-optimal policy. Specicially, we focus on the linear mixture MDP setting, where the probability transition matrix is a (unknown) convex combination of a set of existing models. We show that, by establishing a novel exploration algorithm, the plug-in approach learns a model by taking $\tilde{O}(d^2H^3/\epsilon^2)$ interactions with the environment and \emph{any} $\epsilon$-optimal planner on the model gives an $O(\epsilon)$-optimal policy on the original model. This sample complexity matches lower bounds for non-plug-in approaches and is \emph{statistically optimal}. We achieve this result by leveraging a careful maximum total-variance bound using Bernstein inequality and properties specified to linear mixture MDP.

Understanding Domain Randomization for Sim-to-real Transfer

Reinforcement learning encounters many challenges when applied directly in the real world. Sim-to-real transfer is widely used to transfer the knowledge learned from simulation to the real world. Domain randomization -- one of the most popular algorithms for sim-to-real transfer -- has been demonstrated to be effective in various tasks in robotics and autonomous driving. Despite its empirical successes, theoretical understanding on why this simple algorithm works is limited. In this paper, we propose a theoretical framework for sim-to-real transfers, in which the simulator is modeled as a set of MDPs with tunable parameters (corresponding to unknown physical parameters such as friction). We provide sharp bounds on the sim-to-real gap -- the difference between the value of policy returned by domain randomization and the value of an optimal policy for the real world. We prove that sim-to-real transfer can succeed under mild conditions without any real-world training samples. Our theory also highlights the importance of using memory (i.e., history-dependent policies) in domain randomization. Our proof is based on novel techniques that reduce the problem of bounding the sim-to-real gap to the problem of designing efficient learning algorithms for infinite-horizon MDPs, which we believe are of independent interest.

Deep Structured Instance Graph for Distilling Object Detectors

Effectively structuring deep knowledge plays a pivotal role in transfer from teacher to student, especially in semantic vision tasks. In this paper, we present a simple knowledge structure to exploit and encode information inside the detection system to facilitate detector knowledge distillation. Specifically, aiming at solving the feature imbalance problem while further excavating the missing relation inside semantic instances, we design a graph whose nodes correspond to instance proposal-level features and edges represent the relation between nodes. To further refine this graph, we design an adaptive background loss weight to reduce node noise and background samples mining to prune trivial edges. We transfer the entire graph as encoded knowledge representation from teacher to student, capturing local and global information simultaneously. We achieve new state-of-the-art results on the challenging COCO object detection task with diverse student-teacher pairs on both one- and two-stage detectors. We also experiment with instance segmentation to demonstrate robustness of our method. It is notable that distilled Faster R-CNN with ResNet18-FPN and ResNet50-FPN yields 38.68 and 41.82 Box AP respectively on the COCO benchmark, Faster R-CNN with ResNet101-FPN significantly achieves 43.38 AP, which outperforms ResNet152-FPN teacher about 0.7 AP. Code: https://github.com/dvlab-research/Dsig.

CancerBERT: a BERT model for Extracting Breast Cancer Phenotypes from Electronic Health Records

Accurate extraction of breast cancer patients' phenotypes is important for clinical decision support and clinical research. Current models do not take full advantage of cancer domain-specific corpus, whether pre-training Bidirectional Encoder Representations from Transformer model on cancer-specific corpus could improve the performances of extracting breast cancer phenotypes from texts data remains to be explored. The objective of this study is to develop and evaluate the CancerBERT model for extracting breast cancer phenotypes from clinical texts in electronic health records. This data used in the study included 21,291 breast cancer patients diagnosed from 2010 to 2020, patients' clinical notes and pathology reports were collected from the University of Minnesota Clinical Data Repository (UMN). Results: About 3 million clinical notes and pathology reports in electronic health records for 21,291 breast cancer patients were collected to train the CancerBERT model. 200 pathology reports and 50 clinical notes of breast cancer patients that contain 9,685 sentences and 221,356 tokens were manually annotated by two annotators. 20% of the annotated data was used as a test set. Our CancerBERT model achieved the best performance with macro F1 scores equal to 0.876 (95% CI, 0.896-0.902) for exact match and 0.904 (95% CI, 0.896-0.902) for the lenient match. The NER models we developed would facilitate the automated information extraction from clinical texts to further help clinical decision support. Conclusions and Relevance: In this study, we focused on the breast cancer-related concepts extraction from EHR data and obtained a comprehensive annotated dataset that contains 7 types of breast cancer-related concepts. The CancerBERT model with customized vocabulary could significantly improve the performance for extracting breast cancer phenotypes from clinical texts.