Harmonizing Pathological and Normal Pixels for Pseudo-healthy Synthesis

Synthesizing a subject-specific pathology-free image from a pathological image is valuable for algorithm development and clinical practice. In recent years, several approaches based on the Generative Adversarial Network (GAN) have achieved promising results in pseudo-healthy synthesis. However, the discriminator (i.e., a classifier) in the GAN cannot accurately identify lesions and further hampers from generating admirable pseudo-healthy images. To address this problem, we present a new type of discriminator, the segmentor, to accurately locate the lesions and improve the visual quality of pseudo-healthy images. Then, we apply the generated images into medical image enhancement and utilize the enhanced results to cope with the low contrast problem existing in medical image segmentation. Furthermore, a reliable metric is proposed by utilizing two attributes of label noise to measure the health of synthetic images. Comprehensive experiments on the T2 modality of BraTS demonstrate that the proposed method substantially outperforms the state-of-the-art methods. The method achieves better performance than the existing methods with only 30\% of the training data. The effectiveness of the proposed method is also demonstrated on the LiTS and the T1 modality of BraTS. The code and the pre-trained model of this study are publicly available at https://github.com/Au3C2/Generator-Versus-Segmentor.

Weakly Supervised Learning for cell recognition in immunohistochemical cytoplasm staining images

Cell classification and counting in immunohistochemical cytoplasm staining images play a pivotal role in cancer diagnosis. Weakly supervised learning is a potential method to deal with labor-intensive labeling. However, the inconstant cell morphology and subtle differences between classes also bring challenges. To this end, we present a novel cell recognition framework based on multi-task learning, which utilizes two additional auxiliary tasks to guide robust representation learning of the main task. To deal with misclassification, the tissue prior learning branch is introduced to capture the spatial representation of tumor cells without additional tissue annotation. Moreover, dynamic masks and consistency learning are adopted to learn the invariance of cell scale and shape. We have evaluated our framework on immunohistochemical cytoplasm staining images, and the results demonstrate that our method outperforms recent cell recognition approaches. Besides, we have also done some ablation studies to show significant improvements after adding the auxiliary branches.

Distributed Bandits with Heterogeneous Agents

This paper tackles a multi-agent bandit setting where $M$ agents cooperate together to solve the same instance of a $K$-armed stochastic bandit problem. The agents are \textit{heterogeneous}: each agent has limited access to a local subset of arms and the agents are asynchronous with different gaps between decision-making rounds. The goal for each agent is to find its optimal local arm, and agents can cooperate by sharing their observations with others. While cooperation between agents improves the performance of learning, it comes with an additional complexity of communication between agents. For this heterogeneous multi-agent setting, we propose two learning algorithms, \ucbo and \AAE. We prove that both algorithms achieve order-optimal regret, which is $O\left(\sum_{i:\tilde{\Delta}_i>0} \log T/\tilde{\Delta}_i\right)$, where $\tilde{\Delta}_i$ is the minimum suboptimality gap between the reward mean of arm $i$ and any local optimal arm. In addition, a careful selection of the valuable information for cooperation, \AAE achieves a low communication complexity of $O(\log T)$. Last, numerical experiments verify the efficiency of both algorithms.

Modelling matrix time series via a tensor CP-decomposition

We propose to model matrix time series based on a tensor CP-decomposition. Instead of using an iterative algorithm which is the standard practice for estimating CP-decompositions, we propose a new and one-pass estimation procedure based on a generalized eigenanalysis constructed from the serial dependence structure of the underlying process. A key idea of the new procedure is to project a generalized eigenequation defined in terms of rank-reduced matrices to a lower-dimensional one with full-ranked matrices, to avoid the intricacy of the former of which the number of eigenvalues can be zero, finite and infinity. The asymptotic theory has been established under a general setting without the stationarity. It shows, for example, that all the component coefficient vectors in the CP-decomposition are estimated consistently with the different error rates, depending on the relative sizes between the dimensions of time series and the sample size. The proposed model and the estimation method are further illustrated with both simulated and real data; showing effective dimension-reduction in modelling and forecasting matrix time series.

Hybrid Curriculum Learning for Emotion Recognition in Conversation

Emotion recognition in conversation (ERC) aims to detect the emotion label for each utterance. Motivated by recent studies which have proven that feeding training examples in a meaningful order rather than considering them randomly can boost the performance of models, we propose an ERC-oriented hybrid curriculum learning framework. Our framework consists of two curricula: (1) conversation-level curriculum (CC); and (2) utterance-level curriculum (UC). In CC, we construct a difficulty measurer based on "emotion shift" frequency within a conversation, then the conversations are scheduled in an "easy to hard" schema according to the difficulty score returned by the difficulty measurer. For UC, it is implemented from an emotion-similarity perspective, which progressively strengthens the model's ability in identifying the confusing emotions. With the proposed model-agnostic hybrid curriculum learning strategy, we observe significant performance boosts over a wide range of existing ERC models and we are able to achieve new state-of-the-art results on four public ERC datasets.

Online Speaker Diarization with Graph-based Label Generation

This paper introduces an online speaker diarization system that can handle long-time audio with low latency. First, a new variant of agglomerative hierarchy clustering is built to cluster the speakers in an online fashion. Then, a speaker embedding graph is proposed. We use this graph to exploit a graph-based reclustering method to further improve the performance. Finally, a label matching algorithm is introduced to generate consistent speaker labels, and we evaluate our system on both DIHARD3 and VoxConverse datasets, which contain long audios with various kinds of scenarios. The experimental results show that our online diarization system outperforms the baseline offline system and has comparable performance to our offline system.

Discovery-and-Selection: Towards Optimal Multiple Instance Learning for Weakly Supervised Object Detection

Weakly supervised object detection (WSOD) is a challenging task that requires simultaneously learn object classifiers and estimate object locations under the supervision of image category labels. A major line of WSOD methods roots in multiple instance learning which regards images as bags of instance and selects positive instances from each bag to learn the detector. However, a grand challenge emerges when the detector inclines to converge to discriminative parts of objects rather than the whole objects. In this paper, under the hypothesis that optimal solutions are included in local minima, we propose a discoveryand-selection approach fused with multiple instance learning (DS-MIL), which finds rich local minima and select optimal solutions from multiple local minima. To implement DS-MIL, an attention module is designed so that more context information can be captured by feature maps and more valuable proposals can be collected during training. With proposal candidates, a re-rank module is designed to select informative instances for object detector training. Experimental results on commonly used benchmarks show that our proposed DS-MIL approach can consistently improve the baselines, reporting state-of-the-art performance.

Towards Lightweight Applications: Asymmetric Enroll-Verify Structure for Speaker Verification

With the development of deep learning, automatic speaker verification has made considerable progress over the past few years. However, to design a lightweight and robust system with limited computational resources is still a challenging problem. Traditionally, a speaker verification system is symmetrical, indicating that the same embedding extraction model is applied for both enrollment and verification in inference. In this paper, we come up with an innovative asymmetric structure, which takes the large-scale ECAPA-TDNN model for enrollment and the small-scale ECAPA-TDNNLite model for verification. As a symmetrical system, our proposed ECAPA-TDNNLite model achieves an EER of 3.07% on the Voxceleb1 original test set with only 11.6M FLOPS. Moreover, the asymmetric structure further reduces the EER to 2.31%, without increasing any computational costs during verification.

The DKU-DukeECE-Lenovo System for the Diarization Task of the 2021 VoxCeleb Speaker Recognition Challenge

This report describes the submission of the DKU-DukeECE-Lenovo team to the VoxCeleb Speaker Recognition Challenge (VoxSRC) 2021 track 4. Our system including a voice activity detection (VAD) model, a speaker embedding model, two clustering-based speaker diarization systems with different similarity measurements, two different overlapped speech detection (OSD) models, and a target-speaker voice activity detection (TS-VAD) model. Our final submission, consisting of 5 independent systems, achieves a DER of 5.07% on the challenge test set.

Hierarchical Self-Supervised Learning for Medical Image Segmentation Based on Multi-Domain Data Aggregation

A large labeled dataset is a key to the success of supervised deep learning, but for medical image segmentation, it is highly challenging to obtain sufficient annotated images for model training. In many scenarios, unannotated images are abundant and easy to acquire. Self-supervised learning (SSL) has shown great potentials in exploiting raw data information and representation learning. In this paper, we propose Hierarchical Self-Supervised Learning (HSSL), a new self-supervised framework that boosts medical image segmentation by making good use of unannotated data. Unlike the current literature on task-specific self-supervised pretraining followed by supervised fine-tuning, we utilize SSL to learn task-agnostic knowledge from heterogeneous data for various medical image segmentation tasks. Specifically, we first aggregate a dataset from several medical challenges, then pre-train the network in a self-supervised manner, and finally fine-tune on labeled data. We develop a new loss function by combining contrastive loss and classification loss and pretrain an encoder-decoder architecture for segmentation tasks. Our extensive experiments show that multi-domain joint pre-training benefits downstream segmentation tasks and outperforms single-domain pre-training significantly. Compared to learning from scratch, our new method yields better performance on various tasks (e.g., +0.69% to +18.60% in Dice scores with 5% of annotated data). With limited amounts of training data, our method can substantially bridge the performance gap w.r.t. denser annotations (e.g., 10% vs.~100% of annotated data).