UniX: Unifying Autoregression and Diffusion for Chest X-Ray Understanding and Generation

Despite recent progress, medical foundation models still struggle to unify visual understanding and generation, as these tasks have inherently conflicting goals: semantic abstraction versus pixel-level reconstruction. Existing approaches, typically based on parameter-shared autoregressive architectures, frequently lead to compromised performance in one or both tasks. To address this, we present UniX, a next-generation unified medical foundation model for chest X-ray understanding and generation. UniX decouples the two tasks into an autoregressive branch for understanding and a diffusion branch for high-fidelity generation. Crucially, a cross-modal self-attention mechanism is introduced to dynamically guide the generation process with understanding features. Coupled with a rigorous data cleaning pipeline and a multi-stage training strategy, this architecture enables synergistic collaboration between tasks while leveraging the strengths of diffusion models for superior generation. On two representative benchmarks, UniX achieves a 46.1% improvement in understanding performance (Micro-F1) and a 24.2% gain in generation quality (FD-RadDino), using only a quarter of the parameters of LLM-CXR. By achieving performance on par with task-specific models, our work establishes a scalable paradigm for synergistic medical image understanding and generation. Codes and models are available at https://github.com/ZrH42/UniX.

Panning for Gold: Expanding Domain-Specific Knowledge Graphs with General Knowledge

Domain-specific knowledge graphs (DKGs) often lack coverage compared to general knowledge graphs (GKGs). To address this, we introduce Domain-specific Knowledge Graph Fusion (DKGF), a novel task that enriches DKGs by integrating relevant facts from GKGs. DKGF faces two key challenges: high ambiguity in domain relevance and misalignment in knowledge granularity across graphs. We propose ExeFuse, a simple yet effective Fact-as-Program paradigm. It treats each GKG fact as a latent semantic program, maps abstract relations to granularity-aware operators, and verifies domain relevance via program executability on the target DKG. This unified probabilistic framework jointly resolves relevance and granularity issues. We construct two benchmarks, DKGF(W-I) and DKGF(Y-I), with 21 evaluation configurations. Extensive experiments validate the task's importance and our model's effectiveness, providing the first standardized testbed for DKGF.

Searth Transformer: A Transformer Architecture Incorporating Earth's Geospheric Physical Priors for Global Mid-Range Weather Forecasting

Accurate global medium-range weather forecasting is fundamental to Earth system science. Most existing Transformer-based forecasting models adopt vision-centric architectures that neglect the Earth's spherical geometry and zonal periodicity. In addition, conventional autoregressive training is computationally expensive and limits forecast horizons due to error accumulation. To address these challenges, we propose the Shifted Earth Transformer (Searth Transformer), a physics-informed architecture that incorporates zonal periodicity and meridional boundaries into window-based self-attention for physically consistent global information exchange. We further introduce a Relay Autoregressive (RAR) fine-tuning strategy that enables learning long-range atmospheric evolution under constrained memory and computational budgets. Based on these methods, we develop YanTian, a global medium-range weather forecasting model. YanTian achieves higher accuracy than the high-resolution forecast of the European Centre for Medium-Range Weather Forecasts and performs competitively with state-of-the-art AI models at one-degree resolution, while requiring roughly 200 times lower computational cost than standard autoregressive fine-tuning. Furthermore, YanTian attains a longer skillful forecast lead time for Z500 (10.3 days) than HRES (9 days). Beyond weather forecasting, this work establishes a robust algorithmic foundation for predictive modeling of complex global-scale geophysical circulation systems, offering new pathways for Earth system science.

BalDRO: A Distributionally Robust Optimization based Framework for Large Language Model Unlearning

As Large Language Models (LLMs) increasingly shape online content, removing targeted information from well-trained LLMs (also known as LLM unlearning) has become critical for web governance. A key challenge lies in sample-wise imbalance within the forget set: different samples exhibit widely varying unlearning difficulty, leading to asynchronous forgetting where some knowledge remains insufficiently erased while others become over-forgotten. To address this, we propose BalDRO, a novel and efficient framework for balanced LLM unlearning. BalDRO formulates unlearning as a min-sup process: an inner step identifies a worst-case data distribution that emphasizes hard-to-unlearn samples, while an outer step updates model parameters under this distribution. We instantiate BalDRO via two efficient variants: BalDRO-G, a discrete GroupDRO-based approximation focusing on high-loss subsets, and BalDRO-DV, a continuous Donsker-Varadhan dual method enabling smooth adaptive weighting within standard training pipelines. Experiments on TOFU and MUSE show that BalDRO significantly improves both forgetting quality and model utility over existing methods, and we release code for reproducibility.

SwiftMem: Fast Agentic Memory via Query-aware Indexing

Agentic memory systems have become critical for enabling LLM agents to maintain long-term context and retrieve relevant information efficiently. However, existing memory frameworks suffer from a fundamental limitation: they perform exhaustive retrieval across the entire storage layer regardless of query characteristics. This brute-force approach creates severe latency bottlenecks as memory grows, hindering real-time agent interactions. We propose SwiftMem, a query-aware agentic memory system that achieves sub-linear retrieval through specialized indexing over temporal and semantic dimensions. Our temporal index enables logarithmic-time range queries for time-sensitive retrieval, while the semantic DAG-Tag index maps queries to relevant topics through hierarchical tag structures. To address memory fragmentation during growth, we introduce an embedding-tag co-consolidation mechanism that reorganizes storage based on semantic clusters to improve cache locality. Experiments on LoCoMo and LongMemEval benchmarks demonstrate that SwiftMem achieves 47$\times$ faster search compared to state-of-the-art baselines while maintaining competitive accuracy, enabling practical deployment of memory-augmented LLM agents.

Multi-scale Graph Autoregressive Modeling: Molecular Property Prediction via Next Token Prediction

We present Connection-Aware Motif Sequencing (CamS), a graph-to-sequence representation that enables decoder-only Transformers to learn molecular graphs via standard next-token prediction (NTP). For molecular property prediction, SMILES-based NTP scales well but lacks explicit topology, whereas graph-native masked modeling captures connectivity but risks disrupting the pivotal chemical details (e.g., activity cliffs). CamS bridges this gap by serializing molecular graphs into structure-rich causal sequences. CamS first mines data-driven connection-aware motifs. It then serializes motifs via scaffold-rooted breadth-first search (BFS) to establish a stable core-to-periphery order. Crucially, CamS enables hierarchical modeling by concatenating sequences from fine to coarse motif scales, allowing the model to condition global scaffolds on dense, uncorrupted local structural evidence. We instantiate CamS-LLaMA by pre-training a vanilla LLaMA backbone on CamS sequences. It achieves state-of-the-art performance on MoleculeNet and the activity-cliff benchmark MoleculeACE, outperforming both SMILES-based language models and strong graph baselines. Interpretability analysis confirms that our multi-scale causal serialization effectively drives attention toward cliff-determining differences.

A unified multimodal understanding and generation model for cross-disciplinary scientific research

Scientific discovery increasingly relies on integrating heterogeneous, high-dimensional data across disciplines nowadays. While AI models have achieved notable success across various scientific domains, they typically remain domain-specific or lack the capability of simultaneously understanding and generating multimodal scientific data, particularly for high-dimensional data. Yet, many pressing global challenges and scientific problems are inherently cross-disciplinary and require coordinated progress across multiple fields. Here, we present FuXi-Uni, a native unified multimodal model for scientific understanding and high-fidelity generation across scientific domains within a single architecture. Specifically, FuXi-Uni aligns cross-disciplinary scientific tokens within natural language tokens and employs science decoder to reconstruct scientific tokens, thereby supporting both natural language conversation and scientific numerical prediction. Empirically, we validate FuXi-Uni in Earth science and Biomedicine. In Earth system modeling, the model supports global weather forecasting, tropical cyclone (TC) forecast editing, and spatial downscaling driven by only language instructions. FuXi-Uni generates 10-day global forecasts at 0.25° resolution that outperform the SOTA physical forecasting system. It shows superior performance for both TC track and intensity prediction relative to the SOTA physical model, and generates high-resolution regional weather fields that surpass standard interpolation baselines. Regarding biomedicine, FuXi-Uni outperforms leading multimodal large language models on multiple biomedical visual question answering benchmarks. By unifying heterogeneous scientific modalities within a native shared latent space while maintaining strong domain-specific performance, FuXi-Uni provides a step forward more general-purpose, multimodal scientific models.

NeXT-IMDL: Build Benchmark for NeXT-Generation Image Manipulation Detection & Localization

The accessibility surge and abuse risks of user-friendly image editing models have created an urgent need for generalizable, up-to-date methods for Image Manipulation Detection and Localization (IMDL). Current IMDL research typically uses cross-dataset evaluation, where models trained on one benchmark are tested on others. However, this simplified evaluation approach conceals the fragility of existing methods when handling diverse AI-generated content, leading to misleading impressions of progress. This paper challenges this illusion by proposing NeXT-IMDL, a large-scale diagnostic benchmark designed not just to collect data, but to probe the generalization boundaries of current detectors systematically. Specifically, NeXT-IMDL categorizes AIGC-based manipulations along four fundamental axes: editing models, manipulation types, content semantics, and forgery granularity. Built upon this, NeXT-IMDL implements five rigorous cross-dimension evaluation protocols. Our extensive experiments on 11 representative models reveal a critical insight: while these models perform well in their original settings, they exhibit systemic failures and significant performance degradation when evaluated under our designed protocols that simulate real-world, various generalization scenarios. By providing this diagnostic toolkit and the new findings, we aim to advance the development towards building truly robust, next-generation IMDL models.

A DeepSeek-Powered AI System for Automated Chest Radiograph Interpretation in Clinical Practice

A global shortage of radiologists has been exacerbated by the significant volume of chest X-ray workloads, particularly in primary care. Although multimodal large language models show promise, existing evaluations predominantly rely on automated metrics or retrospective analyses, lacking rigorous prospective clinical validation. Janus-Pro-CXR (1B), a chest X-ray interpretation system based on DeepSeek Janus-Pro model, was developed and rigorously validated through a multicenter prospective trial (NCT07117266). Our system outperforms state-of-the-art X-ray report generation models in automated report generation, surpassing even larger-scale models including ChatGPT 4o (200B parameters), while demonstrating reliable detection of six clinically critical radiographic findings. Retrospective evaluation confirms significantly higher report accuracy than Janus-Pro and ChatGPT 4o. In prospective clinical deployment, AI assistance significantly improved report quality scores, reduced interpretation time by 18.3% (P < 0.001), and was preferred by a majority of experts in 54.3% of cases. Through lightweight architecture and domain-specific optimization, Janus-Pro-CXR improves diagnostic reliability and workflow efficiency, particularly in resource-constrained settings. The model architecture and implementation framework will be open-sourced to facilitate the clinical translation of AI-assisted radiology solutions.

A Large Language Model Based Method for Complex Logical Reasoning over Knowledge Graphs

Reasoning over knowledge graphs (KGs) with first-order logic (FOL) queries is challenging due to the inherent incompleteness of real-world KGs and the compositional complexity of logical query structures. Most existing methods rely on embedding entities and relations into continuous geometric spaces and answer queries via differentiable set operations. While effective for simple query patterns, these approaches often struggle to generalize to complex queries involving multiple operators, deeper reasoning chains, or heterogeneous KG schemas. We propose ROG (Reasoning Over knowledge Graphs with large language models), an ensemble-style framework that combines query-aware KG neighborhood retrieval with large language model (LLM)-based chain-of-thought reasoning. ROG decomposes complex FOL queries into sequences of simpler sub-queries, retrieves compact, query-relevant subgraphs as contextual evidence, and performs step-by-step logical inference using an LLM, avoiding the need for task-specific embedding optimization. Experiments on standard KG reasoning benchmarks demonstrate that ROG consistently outperforms strong embedding-based baselines in terms of mean reciprocal rank (MRR), with particularly notable gains on high-complexity query types. These results suggest that integrating structured KG retrieval with LLM-driven logical reasoning offers a robust and effective alternative for complex KG reasoning tasks.