REARANK: Reasoning Re-ranking Agent via Reinforcement Learning

We present REARANK, a large language model (LLM)-based listwise reasoning reranking agent. REARANK explicitly reasons before reranking, significantly improving both performance and interpretability. Leveraging reinforcement learning and data augmentation, REARANK achieves substantial improvements over baseline models across popular information retrieval benchmarks, notably requiring only 179 annotated samples. Built on top of Qwen2.5-7B, our REARANK-7B demonstrates performance comparable to GPT-4 on both in-domain and out-of-domain benchmarks and even surpasses GPT-4 on reasoning-intensive BRIGHT benchmarks. These results underscore the effectiveness of our approach and highlight how reinforcement learning can enhance LLM reasoning capabilities in reranking.

Semantically-Aware Game Image Quality Assessment

Assessing the visual quality of video game graphics presents unique challenges due to the absence of reference images and the distinct types of distortions, such as aliasing, texture blur, and geometry level of detail (LOD) issues, which differ from those in natural images or user-generated content. Existing no-reference image and video quality assessment (NR-IQA/VQA) methods fail to generalize to gaming environments as they are primarily designed for distortions like compression artifacts. This study introduces a semantically-aware NR-IQA model tailored to gaming. The model employs a knowledge-distilled Game distortion feature extractor (GDFE) to detect and quantify game-specific distortions, while integrating semantic gating via CLIP embeddings to dynamically weight feature importance based on scene content. Training on gameplay data recorded across graphical quality presets enables the model to produce quality scores that align with human perception. Our results demonstrate that the GDFE, trained through knowledge distillation from binary classifiers, generalizes effectively to intermediate distortion levels unseen during training. Semantic gating further improves contextual relevance and reduces prediction variance. In the absence of in-domain NR-IQA baselines, our model outperforms out-of-domain methods and exhibits robust, monotonic quality trends across unseen games in the same genre. This work establishes a foundation for automated graphical quality assessment in gaming, advancing NR-IQA methods in this domain.

Gameplay Highlights Generation

In this work, we enable gamers to share their gaming experience on social media by automatically generating eye-catching highlight reels from their gameplay session Our automation will save time for gamers while increasing audience engagement. We approach the highlight generation problem by first identifying intervals in the video where interesting events occur and then concatenate them. We developed an in-house gameplay event detection dataset containing interesting events annotated by humans using VIA video annotator. Traditional techniques for highlight detection such as game engine integration requires expensive collaboration with game developers. OCR techniques which detect patches of specific images or texts require expensive per game engineering and may not generalize across game UI and different language. We finetuned a multimodal general purpose video understanding model such as X-CLIP using our dataset which generalizes across multiple games in a genre without per game engineering. Prompt engineering was performed to improve the classification performance of this multimodal model. Our evaluation showed that such a finetuned model can detect interesting events in first person shooting games from unseen gameplay footage with more than 90% accuracy. Moreover, our model performed significantly better on low resource games (small dataset) when trained along with high resource games, showing signs of transfer learning. To make the model production ready, we used ONNX libraries to enable cross platform inference. These libraries also provide post training quantization tools to reduce model size and inference time for deployment. ONNX runtime libraries with DirectML backend were used to perform efficient inference on Windows OS. We show that natural language supervision in the X-CLIP model leads to data efficient and highly performant video recognition models.

Prompt to Restore, Restore to Prompt: Cyclic Prompting for Universal Adverse Weather Removal

Universal adverse weather removal (UAWR) seeks to address various weather degradations within a unified framework. Recent methods are inspired by prompt learning using pre-trained vision-language models (e.g., CLIP), leveraging degradation-aware prompts to facilitate weather-free image restoration, yielding significant improvements. In this work, we propose CyclicPrompt, an innovative cyclic prompt approach designed to enhance the effectiveness, adaptability, and generalizability of UAWR. CyclicPrompt Comprises two key components: 1) a composite context prompt that integrates weather-related information and context-aware representations into the network to guide restoration. This prompt differs from previous methods by marrying learnable input-conditional vectors with weather-specific knowledge, thereby improving adaptability across various degradations. 2) The erase-and-paste mechanism, after the initial guided restoration, substitutes weather-specific knowledge with constrained restoration priors, inducing high-quality weather-free concepts into the composite prompt to further fine-tune the restoration process. Therefore, we can form a cyclic "Prompt-Restore-Prompt" pipeline that adeptly harnesses weather-specific knowledge, textual contexts, and reliable textures. Extensive experiments on synthetic and real-world datasets validate the superior performance of CyclicPrompt. The code is available at: https://github.com/RongxinL/CyclicPrompt.

DeepNuParc: A Novel Deep Clustering Framework for Fine-scale Parcellation of Brain Nuclei Using Diffusion MRI Tractography

Brain nuclei are clusters of anatomically distinct neurons that serve as important hubs for processing and relaying information in various neural circuits. Fine-scale parcellation of the brain nuclei is vital for a comprehensive understanding of its anatomico-functional correlations. Diffusion MRI tractography is an advanced imaging technique that can estimate the brain's white matter structural connectivity to potentially reveal the topography of the nuclei of interest for studying its subdivisions. In this work, we present a deep clustering pipeline, namely DeepNuParc, to perform automated, fine-scale parcellation of brain nuclei using diffusion MRI tractography. First, we incorporate a newly proposed deep learning approach to enable accurate segmentation of the nuclei of interest directly on the dMRI data. Next, we design a novel streamline clustering-based structural connectivity feature for a robust representation of voxels within the nuclei. Finally, we improve the popular joint dimensionality reduction and k-means clustering approach to enable nuclei parcellation at a finer scale. We demonstrate DeepNuParc on two important brain structures, i.e. the amygdala and the thalamus, that are known to have multiple anatomically and functionally distinct nuclei subdivisions. Experimental results show that DeepNuParc enables consistent parcellation of the nuclei into multiple parcels across multiple subjects and achieves good correspondence with the widely used coarse-scale atlases. Our codes are available at https://github.com/HarlandZZC/deep_nuclei_parcellation.

TimeFound: A Foundation Model for Time Series Forecasting

We present TimeFound, an encoder-decoder transformer-based time series foundation model for out-of-the-box zero-shot forecasting. To handle time series data from various domains, TimeFound employs a multi-resolution patching strategy to capture complex temporal patterns at multiple scales. We pre-train our model with two sizes (200M and 710M parameters) on a large time-series corpus comprising both real-world and synthetic datasets. Over a collection of unseen datasets across diverse domains and forecasting horizons, our empirical evaluations suggest that TimeFound can achieve superior or competitive zero-shot forecasting performance, compared to state-of-the-art time series foundation models.

DiffKAN-Inpainting: KAN-based Diffusion model for brain tumor inpainting

Brain tumors delay the standard preprocessing workflow for further examination. Brain inpainting offers a viable, although difficult, solution for tumor tissue processing, which is necessary to improve the precision of the diagnosis and treatment. Most conventional U-Net-based generative models, however, often face challenges in capturing the complex, nonlinear latent representations inherent in brain imaging. In order to accomplish high-quality healthy brain tissue reconstruction, this work proposes DiffKAN-Inpainting, an innovative method that blends diffusion models with the Kolmogorov-Arnold Networks architecture. During the denoising process, we introduce the RePaint method and tumor information to generate images with a higher fidelity and smoother margin. Both qualitative and quantitative results demonstrate that as compared to the state-of-the-art methods, our proposed DiffKAN-Inpainting inpaints more detailed and realistic reconstructions on the BraTS dataset. The knowledge gained from ablation study provide insights for future research to balance performance with computing cost.

Offload Rethinking by Cloud Assistance for Efficient Environmental Sound Recognition on LPWANs

Learning-based environmental sound recognition has emerged as a crucial method for ultra-low-power environmental monitoring in biological research and city-scale sensing systems. These systems usually operate under limited resources and are often powered by harvested energy in remote areas. Recent efforts in on-device sound recognition suffer from low accuracy due to resource constraints, whereas cloud offloading strategies are hindered by high communication costs. In this work, we introduce ORCA, a novel resource-efficient cloud-assisted environmental sound recognition system on batteryless devices operating over the Low-Power Wide-Area Networks (LPWANs), targeting wide-area audio sensing applications. We propose a cloud assistance strategy that remedies the low accuracy of on-device inference while minimizing the communication costs for cloud offloading. By leveraging a self-attention-based cloud sub-spectral feature selection method to facilitate efficient on-device inference, ORCA resolves three key challenges for resource-constrained cloud offloading over LPWANs: 1) high communication costs and low data rates, 2) dynamic wireless channel conditions, and 3) unreliable offloading. We implement ORCA on an energy-harvesting batteryless microcontroller and evaluate it in a real world urban sound testbed. Our results show that ORCA outperforms state-of-the-art methods by up to $80 \times$ in energy savings and $220 \times$ in latency reduction while maintaining comparable accuracy.

Strategic priorities for transformative progress in advancing biology with proteomics and artificial intelligence

Artificial intelligence (AI) is transforming scientific research, including proteomics. Advances in mass spectrometry (MS)-based proteomics data quality, diversity, and scale, combined with groundbreaking AI techniques, are unlocking new challenges and opportunities in biological discovery. Here, we highlight key areas where AI is driving innovation, from data analysis to new biological insights. These include developing an AI-friendly ecosystem for proteomics data generation, sharing, and analysis; improving peptide and protein identification and quantification; characterizing protein-protein interactions and protein complexes; advancing spatial and perturbation proteomics; integrating multi-omics data; and ultimately enabling AI-empowered virtual cells.

KPIs 2024 Challenge: Advancing Glomerular Segmentation from Patch- to Slide-Level

Chronic kidney disease (CKD) is a major global health issue, affecting over 10% of the population and causing significant mortality. While kidney biopsy remains the gold standard for CKD diagnosis and treatment, the lack of comprehensive benchmarks for kidney pathology segmentation hinders progress in the field. To address this, we organized the Kidney Pathology Image Segmentation (KPIs) Challenge, introducing a dataset that incorporates preclinical rodent models of CKD with over 10,000 annotated glomeruli from 60+ Periodic Acid Schiff (PAS)-stained whole slide images. The challenge includes two tasks, patch-level segmentation and whole slide image segmentation and detection, evaluated using the Dice Similarity Coefficient (DSC) and F1-score. By encouraging innovative segmentation methods that adapt to diverse CKD models and tissue conditions, the KPIs Challenge aims to advance kidney pathology analysis, establish new benchmarks, and enable precise, large-scale quantification for disease research and diagnosis.