KEDRec-LM: A Knowledge-distilled Explainable Drug Recommendation Large Language Model

Drug discovery is a critical task in biomedical natural language processing (NLP), yet explainable drug discovery remains underexplored. Meanwhile, large language models (LLMs) have shown remarkable abilities in natural language understanding and generation. Leveraging LLMs for explainable drug discovery has the potential to improve downstream tasks and real-world applications. In this study, we utilize open-source drug knowledge graphs, clinical trial data, and PubMed publications to construct a comprehensive dataset for the explainable drug discovery task, named \textbf{expRxRec}. Furthermore, we introduce \textbf{KEDRec-LM}, an instruction-tuned LLM which distills knowledge from rich medical knowledge corpus for drug recommendation and rationale generation. To encourage further research in this area, we will publicly release\footnote{A copy is attached with this submission} both the dataset and KEDRec-LM.

HetFS: A Method for Fast Similarity Search with Ad-hoc Meta-paths on Heterogeneous Information Networks

Numerous real-world information networks form Heterogeneous Information Networks (HINs) with diverse objects and relations represented as nodes and edges in heterogeneous graphs. Similarity between nodes quantifies how closely two nodes resemble each other, mainly depending on the similarity of the nodes they are connected to, recursively. Users may be interested in only specific types of connections in the similarity definition, represented as meta-paths, i.e., a sequence of node and edge types. Existing Heterogeneous Graph Neural Network (HGNN)-based similarity search methods may accommodate meta-paths, but require retraining for different meta-paths. Conversely, existing path-based similarity search methods may switch flexibly between meta-paths but often suffer from lower accuracy, as they rely solely on path information. This paper proposes HetFS, a Fast Similarity method for ad-hoc queries with user-given meta-paths on Heterogeneous information networks. HetFS provides similarity results based on path information that satisfies the meta-path restriction, as well as node content. Extensive experiments demonstrate the effectiveness and efficiency of HetFS in addressing ad-hoc queries, outperforming state-of-the-art HGNNs and path-based approaches, and showing strong performance in downstream applications, including link prediction, node classification, and clustering.

Exploring Embodied Multimodal Large Models: Development, Datasets, and Future Directions

Embodied multimodal large models (EMLMs) have gained significant attention in recent years due to their potential to bridge the gap between perception, cognition, and action in complex, real-world environments. This comprehensive review explores the development of such models, including Large Language Models (LLMs), Large Vision Models (LVMs), and other models, while also examining other emerging architectures. We discuss the evolution of EMLMs, with a focus on embodied perception, navigation, interaction, and simulation. Furthermore, the review provides a detailed analysis of the datasets used for training and evaluating these models, highlighting the importance of diverse, high-quality data for effective learning. The paper also identifies key challenges faced by EMLMs, including issues of scalability, generalization, and real-time decision-making. Finally, we outline future directions, emphasizing the integration of multimodal sensing, reasoning, and action to advance the development of increasingly autonomous systems. By providing an in-depth analysis of state-of-the-art methods and identifying critical gaps, this paper aims to inspire future advancements in EMLMs and their applications across diverse domains.

SentiFormer: Metadata Enhanced Transformer for Image Sentiment Analysis

As more and more internet users post images online to express their daily emotions, image sentiment analysis has attracted increasing attention. Recently, researchers generally tend to design different neural networks to extract visual features from images for sentiment analysis. Despite the significant progress, metadata, the data (e.g., text descriptions and keyword tags) for describing the image, has not been sufficiently explored in this task. In this paper, we propose a novel Metadata Enhanced Transformer for sentiment analysis (SentiFormer) to fuse multiple metadata and the corresponding image into a unified framework. Specifically, we first obtain multiple metadata of the image and unify the representations of diverse data. To adaptively learn the appropriate weights for each metadata, we then design an adaptive relevance learning module to highlight more effective information while suppressing weaker ones. Moreover, we further develop a cross-modal fusion module to fuse the adaptively learned representations and make the final prediction. Extensive experiments on three publicly available datasets demonstrate the superiority and rationality of our proposed method.

Fact or Guesswork? Evaluating Large Language Model's Medical Knowledge with Structured One-Hop Judgment

Large language models (LLMs) have been widely adopted in various downstream task domains. However, their ability to directly recall and apply factual medical knowledge remains under-explored. Most existing medical QA benchmarks assess complex reasoning or multi-hop inference, making it difficult to isolate LLMs' inherent medical knowledge from their reasoning capabilities. Given the high-stakes nature of medical applications, where incorrect information can have critical consequences, it is essential to evaluate how well LLMs encode, retain, and recall fundamental medical facts. To bridge this gap, we introduce the Medical Knowledge Judgment, a dataset specifically designed to measure LLMs' one-hop factual medical knowledge. MKJ is constructed from the Unified Medical Language System (UMLS), a large-scale repository of standardized biomedical vocabularies and knowledge graphs. We frame knowledge assessment as a binary judgment task, requiring LLMs to verify the correctness of medical statements extracted from reliable and structured knowledge sources. Our experiments reveal that LLMs struggle with factual medical knowledge retention, exhibiting significant performance variance across different semantic categories, particularly for rare medical conditions. Furthermore, LLMs show poor calibration, often being overconfident in incorrect answers. To mitigate these issues, we explore retrieval-augmented generation, demonstrating its effectiveness in improving factual accuracy and reducing uncertainty in medical decision-making.

Reducing Hallucinations of Medical Multimodal Large Language Models with Visual Retrieval-Augmented Generation

Multimodal Large Language Models (MLLMs) have shown impressive performance in vision and text tasks. However, hallucination remains a major challenge, especially in fields like healthcare where details are critical. In this work, we show how MLLMs may be enhanced to support Visual RAG (V-RAG), a retrieval-augmented generation framework that incorporates both text and visual data from retrieved images. On the MIMIC-CXR chest X-ray report generation and Multicare medical image caption generation datasets, we show that Visual RAG improves the accuracy of entity probing, which asks whether a medical entities is grounded by an image. We show that the improvements extend both to frequent and rare entities, the latter of which may have less positive training data. Downstream, we apply V-RAG with entity probing to correct hallucinations and generate more clinically accurate X-ray reports, obtaining a higher RadGraph-F1 score.

Chinese Spelling Correction: A Comprehensive Survey of Progress, Challenges, and Opportunities

Chinese Spelling Correction (CSC) is a critical task in natural language processing, aimed at detecting and correcting spelling errors in Chinese text. This survey provides a comprehensive overview of CSC, tracing its evolution from pre-trained language models to large language models, and critically analyzing their respective strengths and weaknesses in this domain. Moreover, we further present a detailed examination of existing benchmark datasets, highlighting their inherent challenges and limitations. Finally, we propose promising future research directions, particularly focusing on leveraging the potential of LLMs and their reasoning capabilities for improved CSC performance. To the best of our knowledge, this is the first comprehensive survey dedicated to the field of CSC. We believe this work will serve as a valuable resource for researchers, fostering a deeper understanding of the field and inspiring future advancements.

Unveiling the Magic of Code Reasoning through Hypothesis Decomposition and Amendment

The reasoning abilities are one of the most enigmatic and captivating aspects of large language models (LLMs). Numerous studies are dedicated to exploring and expanding the boundaries of this reasoning capability. However, tasks that embody both reasoning and recall characteristics are often overlooked. In this paper, we introduce such a novel task, code reasoning, to provide a new perspective for the reasoning abilities of LLMs. We summarize three meta-benchmarks based on established forms of logical reasoning, and instantiate these into eight specific benchmark tasks. Our testing on these benchmarks reveals that LLMs continue to struggle with identifying satisfactory reasoning pathways. Additionally, we present a new pathway exploration pipeline inspired by human intricate problem-solving methods. This Reflective Hypothesis Decomposition and Amendment (RHDA) pipeline consists of the following iterative steps: (1) Proposing potential hypotheses based on observations and decomposing them; (2) Utilizing tools to validate hypotheses and reflection outcomes; (3) Revising hypothesis in light of observations. Our approach effectively mitigates logical chain collapses arising from forgetting or hallucination issues in multi-step reasoning, resulting in performance gains of up to $3\times$. Finally, we expanded this pipeline by applying it to simulate complex household tasks in real-world scenarios, specifically in VirtualHome, enhancing the handling of failure cases. We release our code and all of results at https://github.com/TnTWoW/code_reasoning.

MoLoRec: A Generalizable and Efficient Framework for LLM-Based Recommendation

Large Language Models (LLMs) have achieved remarkable success in recent years, owing to their impressive generalization capabilities and rich world knowledge. To capitalize on the potential of using LLMs as recommender systems, mainstream approaches typically focus on two paradigms. The first paradigm designs multi-domain or multi-task instruction data for generalizable recommendation, so as to align LLMs with general recommendation areas and deal with cold-start recommendation. The second paradigm enhances domain-specific recommendation tasks with parameter-efficient fine-tuning techniques, in order to improve models under the warm recommendation scenarios. While most previous works treat these two paradigms separately, we argue that they have complementary advantages, and combining them together would be helpful. To that end, in this paper, we propose a generalizable and efficient LLM-based recommendation framework MoLoRec. Our approach starts by parameter-efficient fine-tuning a domain-general module with general recommendation instruction data, to align LLM with recommendation knowledge. Then, given users' behavior of a specific domain, we construct a domain-specific instruction dataset and apply efficient fine-tuning to the pre-trained LLM. After that, we provide approaches to integrate the above domain-general part and domain-specific part with parameters mixture. Please note that, MoLoRec is efficient with plug and play, as the domain-general module is trained only once, and any domain-specific plug-in can be efficiently merged with only domain-specific fine-tuning. Extensive experiments on multiple datasets under both warm and cold-start recommendation scenarios validate the effectiveness and generality of the proposed MoLoRec.

FedKD-hybrid: Federated Hybrid Knowledge Distillation for Lithography Hotspot Detection

Federated Learning (FL) provides novel solutions for machine learning (ML)-based lithography hotspot detection (LHD) under distributed privacy-preserving settings. Currently, two research pipelines have been investigated to aggregate local models and achieve global consensus, including parameter/nonparameter based (also known as knowledge distillation, namely KD). While these two kinds of methods show effectiveness in specific scenarios, we note they have not fully utilized and transferred the information learned, leaving the potential of FL-based LDH remains unexplored. Thus, we propose FedKDhybrid in this study to mitigate the research gap. Specifically, FedKD-hybrid clients agree on several identical layers across all participants and a public dataset for achieving global consensus. During training, the trained local model will be evaluated on the public dataset, and the generated logits will be uploaded along with the identical layer parameters. The aggregated information is consequently used to update local models via the public dataset as a medium. We compare our proposed FedKD-hybrid with several state-of-the-art (SOTA) FL methods under ICCAD-2012 and FAB (real-world collected) datasets with different settings; the experimental results demonstrate the superior performance of the FedKD-hybrid algorithm. Our code is available at https://github.com/itsnotacie/NN-FedKD-hybrid