MedEval: A Multi-Level, Multi-Task, and Multi-Domain Medical Benchmark for Language Model Evaluation

Curated datasets for healthcare are often limited due to the need of human annotations from experts. In this paper, we present MedEval, a multi-level, multi-task, and multi-domain medical benchmark to facilitate the development of language models for healthcare. MedEval is comprehensive and consists of data from several healthcare systems and spans 35 human body regions from 8 examination modalities. With 22,779 collected sentences and 21,228 reports, we provide expert annotations at multiple levels, offering a granular potential usage of the data and supporting a wide range of tasks. Moreover, we systematically evaluated 10 generic and domain-specific language models under zero-shot and finetuning settings, from domain-adapted baselines in healthcare to general-purposed state-of-the-art large language models (e.g., ChatGPT). Our evaluations reveal varying effectiveness of the two categories of language models across different tasks, from which we notice the importance of instruction tuning for few-shot usage of large language models. Our investigation paves the way toward benchmarking language models for healthcare and provides valuable insights into the strengths and limitations of adopting large language models in medical domains, informing their practical applications and future advancements.

Driving through the Concept Gridlock: Unraveling Explainability Bottlenecks in Automated Driving

Concept bottleneck models have been successfully used for explainable machine learning by encoding information within the model with a set of human-defined concepts. In the context of human-assisted or autonomous driving, explainability models can help user acceptance and understanding of decisions made by the autonomous vehicle, which can be used to rationalize and explain driver or vehicle behavior. We propose a new approach using concept bottlenecks as visual features for control command predictions and explanations of user and vehicle behavior. We learn a human-understandable concept layer that we use to explain sequential driving scenes while learning vehicle control commands. This approach can then be used to determine whether a change in a preferred gap or steering commands from a human (or autonomous vehicle) is led by an external stimulus or change in preferences. We achieve competitive performance to latent visual features while gaining interpretability within our model setup.

Off-Policy Evaluation for Large Action Spaces via Policy Convolution

Developing accurate off-policy estimators is crucial for both evaluating and optimizing for new policies. The main challenge in off-policy estimation is the distribution shift between the logging policy that generates data and the target policy that we aim to evaluate. Typically, techniques for correcting distribution shift involve some form of importance sampling. This approach results in unbiased value estimation but often comes with the trade-off of high variance, even in the simpler case of one-step contextual bandits. Furthermore, importance sampling relies on the common support assumption, which becomes impractical when the action space is large. To address these challenges, we introduce the Policy Convolution (PC) family of estimators. These methods leverage latent structure within actions -- made available through action embeddings -- to strategically convolve the logging and target policies. This convolution introduces a unique bias-variance trade-off, which can be controlled by adjusting the amount of convolution. Our experiments on synthetic and benchmark datasets demonstrate remarkable mean squared error (MSE) improvements when using PC, especially when either the action space or policy mismatch becomes large, with gains of up to 5 - 6 orders of magnitude over existing estimators.

Unsupervised Lead Sheet Generation via Semantic Compression

Lead sheets have become commonplace in generative music research, being used as an initial compressed representation for downstream tasks like multitrack music generation and automatic arrangement. Despite this, researchers have often fallen back on deterministic reduction methods (such as the skyline algorithm) to generate lead sheets when seeking paired lead sheets and full scores, with little attention being paid toward the quality of the lead sheets themselves and how they accurately reflect their orchestrated counterparts. To address these issues, we propose the problem of conditional lead sheet generation (i.e. generating a lead sheet given its full score version), and show that this task can be formulated as an unsupervised music compression task, where the lead sheet represents a compressed latent version of the score. We introduce a novel model, called Lead-AE, that models the lead sheets as a discrete subselection of the original sequence, using a differentiable top-k operator to allow for controllable local sparsity constraints. Across both automatic proxy tasks and direct human evaluations, we find that our method improves upon the established deterministic baseline and produces coherent reductions of large multitrack scores.

Farzi Data: Autoregressive Data Distillation

We study data distillation for auto-regressive machine learning tasks, where the input and output have a strict left-to-right causal structure. More specifically, we propose Farzi, which summarizes an event sequence dataset into a small number of synthetic sequences -- Farzi Data -- which are optimized to maintain (if not improve) model performance compared to training on the full dataset. Under the hood, Farzi conducts memory-efficient data distillation by (i) deriving efficient reverse-mode differentiation of the Adam optimizer by leveraging Hessian-Vector Products; and (ii) factorizing the high-dimensional discrete event-space into a latent-space which provably promotes implicit regularization. Empirically, for sequential recommendation and language modeling tasks, we are able to achieve 98-120% of downstream full-data performance when training state-of-the-art models on Farzi Data of size as little as 0.1% of the original dataset. Notably, being able to train better models with significantly less data sheds light on the design of future large auto-regressive models, and opens up new opportunities to further scale up model and data sizes.

SelfVC: Voice Conversion With Iterative Refinement using Self Transformations

We propose SelfVC, a training strategy to iteratively improve a voice conversion model with self-synthesized examples. Previous efforts on voice conversion focus on explicitly disentangling speech representations to separately encode speaker characteristics and linguistic content. However, disentangling speech representations to capture such attributes using task-specific loss terms can lead to information loss by discarding finer nuances of the original signal. In this work, instead of explicitly disentangling attributes with loss terms, we present a framework to train a controllable voice conversion model on entangled speech representations derived from self-supervised learning and speaker verification models. First, we develop techniques to derive prosodic information from the audio signal and SSL representations to train predictive submodules in the synthesis model. Next, we propose a training strategy to iteratively improve the synthesis model for voice conversion, by creating a challenging training objective using self-synthesized examples. In this training approach, the current state of the synthesis model is used to generate voice-converted variations of an utterance, which serve as inputs for the reconstruction task, ensuring a continuous and purposeful refinement of the model. We demonstrate that incorporating such self-synthesized examples during training improves the speaker similarity of generated speech as compared to a baseline voice conversion model trained solely on heuristically perturbed inputs. SelfVC is trained without any text and is applicable to a range of tasks such as zero-shot voice conversion, cross-lingual voice conversion, and controllable speech synthesis with pitch and pace modifications. SelfVC achieves state-of-the-art results in zero-shot voice conversion on metrics evaluating naturalness, speaker similarity, and intelligibility of synthesized audio.

AgentCF: Collaborative Learning with Autonomous Language Agents for Recommender Systems

Recently, there has been an emergence of employing LLM-powered agents as believable human proxies, based on their remarkable decision-making capability. However, existing studies mainly focus on simulating human dialogue. Human non-verbal behaviors, such as item clicking in recommender systems, although implicitly exhibiting user preferences and could enhance the modeling of users, have not been deeply explored. The main reasons lie in the gap between language modeling and behavior modeling, as well as the incomprehension of LLMs about user-item relations. To address this issue, we propose AgentCF for simulating user-item interactions in recommender systems through agent-based collaborative filtering. We creatively consider not only users but also items as agents, and develop a collaborative learning approach that optimizes both kinds of agents together. Specifically, at each time step, we first prompt the user and item agents to interact autonomously. Then, based on the disparities between the agents' decisions and real-world interaction records, user and item agents are prompted to reflect on and adjust the misleading simulations collaboratively, thereby modeling their two-sided relations. The optimized agents can also propagate their preferences to other agents in subsequent interactions, implicitly capturing the collaborative filtering idea. Overall, the optimized agents exhibit diverse interaction behaviors within our framework, including user-item, user-user, item-item, and collective interactions. The results show that these agents can demonstrate personalized behaviors akin to those of real-world individuals, sparking the development of next-generation user behavior simulation.

Robust and Interpretable Medical Image Classifiers via Concept Bottleneck Models

Medical image classification is a critical problem for healthcare, with the potential to alleviate the workload of doctors and facilitate diagnoses of patients. However, two challenges arise when deploying deep learning models to real-world healthcare applications. First, neural models tend to learn spurious correlations instead of desired features, which could fall short when generalizing to new domains (e.g., patients with different ages). Second, these black-box models lack interpretability. When making diagnostic predictions, it is important to understand why a model makes a decision for trustworthy and safety considerations. In this paper, to address these two limitations, we propose a new paradigm to build robust and interpretable medical image classifiers with natural language concepts. Specifically, we first query clinical concepts from GPT-4, then transform latent image features into explicit concepts with a vision-language model. We systematically evaluate our method on eight medical image classification datasets to verify its effectiveness. On challenging datasets with strong confounding factors, our method can mitigate spurious correlations thus substantially outperform standard visual encoders and other baselines. Finally, we show how classification with a small number of concepts brings a level of interpretability for understanding model decisions through case studies in real medical data.

Linear Recurrent Units for Sequential Recommendation

State-of-the-art sequential recommendation relies heavily on self-attention-based recommender models. Yet such models are computationally expensive and often too slow for real-time recommendation. Furthermore, the self-attention operation is performed at a sequence-level, thereby making low-cost incremental inference challenging. Inspired by recent advances in efficient language modeling, we propose linear recurrent units for sequential recommendation (LRURec). Similar to recurrent neural networks, LRURec offers rapid inference and can achieve incremental inference on sequential inputs. By decomposing the linear recurrence operation and designing recursive parallelization in our framework, LRURec provides the additional benefits of reduced model size and parallelizable training. Moreover, we optimize the architecture of LRURec by implementing a series of modifications to address the lack of non-linearity and improve training dynamics. To validate the effectiveness of our proposed LRURec, we conduct extensive experiments on multiple real-world datasets and compare its performance against state-of-the-art sequential recommenders. Experimental results demonstrate the effectiveness of LRURec, which consistently outperforms baselines by a significant margin. Results also highlight the efficiency of LRURec with our parallelized training paradigm and fast inference on long sequences, showing its potential to further enhance user experience in sequential recommendation.

Contrastive Post-training Large Language Models on Data Curriculum

Alignment serves as an important step to steer large language models (LLMs) towards human preferences. In this paper, we explore contrastive post-training techniques for alignment by automatically constructing preference pairs from multiple models of varying strengths (e.g., InstructGPT, ChatGPT and GPT-4). We carefully compare the contrastive techniques of SLiC and DPO to SFT baselines and find that DPO provides a step-function improvement even after continueing SFT saturates. We also explore a data curriculum learning scheme for contrastive post-training, which starts by learning from "easier" pairs and transitioning to "harder" ones, which further improves alignment. Finally, we scale up our experiments to train with more data and larger models like Orca. Remarkably, contrastive post-training further improves the performance of Orca, already a state-of-the-art instruction learning model tuned with GPT-4 outputs, to exceed that of ChatGPT.