Evaluating Large Language Models in Ophthalmology

Purpose: The performance of three different large language models (LLMS) (GPT-3.5, GPT-4, and PaLM2) in answering ophthalmology professional questions was evaluated and compared with that of three different professional populations (medical undergraduates, medical masters, and attending physicians). Methods: A 100-item ophthalmology single-choice test was administered to three different LLMs (GPT-3.5, GPT-4, and PaLM2) and three different professional levels (medical undergraduates, medical masters, and attending physicians), respectively. The performance of LLM was comprehensively evaluated and compared with the human group in terms of average score, stability, and confidence. Results: Each LLM outperformed undergraduates in general, with GPT-3.5 and PaLM2 being slightly below the master's level, while GPT-4 showed a level comparable to that of attending physicians. In addition, GPT-4 showed significantly higher answer stability and confidence than GPT-3.5 and PaLM2. Conclusion: Our study shows that LLM represented by GPT-4 performs better in the field of ophthalmology. With further improvements, LLM will bring unexpected benefits in medical education and clinical decision making in the near future.

Evaluating multiple large language models in pediatric ophthalmology

IMPORTANCE The response effectiveness of different large language models (LLMs) and various individuals, including medical students, graduate students, and practicing physicians, in pediatric ophthalmology consultations, has not been clearly established yet. OBJECTIVE Design a 100-question exam based on pediatric ophthalmology to evaluate the performance of LLMs in highly specialized scenarios and compare them with the performance of medical students and physicians at different levels. DESIGN, SETTING, AND PARTICIPANTS This survey study assessed three LLMs, namely ChatGPT (GPT-3.5), GPT-4, and PaLM2, were assessed alongside three human cohorts: medical students, postgraduate students, and attending physicians, in their ability to answer questions related to pediatric ophthalmology. It was conducted by administering questionnaires in the form of test papers through the LLM network interface, with the valuable participation of volunteers. MAIN OUTCOMES AND MEASURES Mean scores of LLM and humans on 100 multiple-choice questions, as well as the answer stability, correlation, and response confidence of each LLM. RESULTS GPT-4 performed comparably to attending physicians, while ChatGPT (GPT-3.5) and PaLM2 outperformed medical students but slightly trailed behind postgraduate students. Furthermore, GPT-4 exhibited greater stability and confidence when responding to inquiries compared to ChatGPT (GPT-3.5) and PaLM2. CONCLUSIONS AND RELEVANCE Our results underscore the potential for LLMs to provide medical assistance in pediatric ophthalmology and suggest significant capacity to guide the education of medical students.

A Novel Deep Reinforcement Learning Based Automated Stock Trading System Using Cascaded LSTM Networks

More and more stock trading strategies are constructed using deep reinforcement learning (DRL) algorithms, but DRL methods originally widely used in the gaming community are not directly adaptable to financial data with low signal-to-noise ratios and unevenness, and thus suffer from performance shortcomings. In this paper, to capture the hidden information, we propose a DRL based stock trading system using cascaded LSTM, which first uses LSTM to extract the time-series features from stock daily data, and then the features extracted are fed to the agent for training, while the strategy functions in reinforcement learning also use another LSTM for training. Experiments in DJI in the US market and SSE50 in the Chinese stock market show that our model outperforms previous baseline models in terms of cumulative returns and Sharp ratio, and this advantage is more significant in the Chinese stock market, a merging market. It indicates that our proposed method is a promising way to build a automated stock trading system.

Paint4Poem: A Dataset for Artistic Visualization of Classical Chinese Poems

In this work we propose a new task: artistic visualization of classical Chinese poems, where the goal is to generatepaintings of a certain artistic style for classical Chinese poems. For this purpose, we construct a new dataset called Paint4Poem. Thefirst part of Paint4Poem consists of 301 high-quality poem-painting pairs collected manually from an influential modern Chinese artistFeng Zikai. As its small scale poses challenges for effectively training poem-to-painting generation models, we introduce the secondpart of Paint4Poem, which consists of 3,648 caption-painting pairs collected manually from Feng Zikai's paintings and 89,204 poem-painting pairs collected automatically from the web. We expect the former to help learning the artist painting style as it containshis most paintings, and the latter to help learning the semantic relevance between poems and paintings. Further, we analyze Paint4Poem regarding poem diversity, painting style, and the semantic relevance between poems and paintings. We create abenchmark for Paint4Poem: we train two representative text-to-image generation models: AttnGAN and MirrorGAN, and evaluate theirperformance regarding painting pictorial quality, painting stylistic relevance, and semantic relevance between poems and paintings.The results indicate that the models are able to generate paintings that have good pictorial quality and mimic Feng Zikai's style, but thereflection of poem semantics is limited. The dataset also poses many interesting research directions on this task, including transferlearning, few-shot learning, text-to-image generation for low-resource data etc. The dataset is publicly available.(https://github.com/paint4poem/paint4poem)

Fermion Sampling Made More Efficient

Fermion sampling is to generate probability distribution of a many-body Slater-determinant wavefunction, which is termed "determinantal point process" in statistical analysis. For its inherently-embedded Pauli exclusion principle, its application reaches beyond simulating fermionic quantum many-body physics to constructing machine learning models for diversified datasets. Here we propose a fermion sampling algorithm, which has a polynomial time-complexity -- quadratic in the fermion number and linear in the system size. This algorithm is about 100% more efficient in computation time than the best known algorithms. In sampling the corresponding marginal distribution, our algorithm has a more drastic improvement, achieving a scaling advantage. We demonstrate its power on several test applications, including sampling fermions in a many-body system and a machine learning task of text summarization, and confirm its improved computation efficiency over other methods by counting floating-point operations.

Category Aware Explainable Conversational Recommendation

Most conversational recommendation approaches are either not explainable, or they require external user's knowledge for explaining or their explanations cannot be applied in real time due to computational limitations. In this work, we present a real time category based conversational recommendation approach, which can provide concise explanations without prior user knowledge being required. We first perform an explainable user model in the form of preferences over the items' categories, and then use the category preferences to recommend items. The user model is performed by applying a BERT-based neural architecture on the conversation. Then, we translate the user model into item recommendation scores using a Feed Forward Network. User preferences during the conversation in our approach are represented by category vectors which are directly interpretable. The experimental results on the real conversational recommendation dataset ReDial demonstrate comparable performance to the state-of-the-art, while our approach is explainable. We also show the potential power of our framework by involving an oracle setting of category preference prediction.

An Empirical Study of Clarifying Question-Based Systems

Search and recommender systems that take the initiative to ask clarifying questions to better understand users' information needs are receiving increasing attention from the research community. However, to the best of our knowledge, there is no empirical study to quantify whether and to what extent users are willing or able to answer these questions. In this work, we conduct an online experiment by deploying an experimental system, which interacts with users by asking clarifying questions against a product repository. We collect both implicit interaction behavior data and explicit feedback from users showing that: (a) users are willing to answer a good number of clarifying questions (11-21 on average), but not many more than that; (b) most users answer questions until they reach the target product, but also a fraction of them stops due to fatigue or due to receiving irrelevant questions; (c) part of the users' answers (12-17%) are actually opposite to the description of the target product; while (d) most of the users (66-84%) find the question-based system helpful towards completing their tasks. Some of the findings of the study contradict current assumptions on simulated evaluations in the field, while they point towards improvements in the evaluation framework and can inspire future interactive search/recommender system designs.

A Class-Incremental Learning Method Based on One Class Support Vector Machine

A method based on one class support vector machine (OCSVM) is proposed for class incremental learning. Several OCSVM models divide the input space into several parts. Then, the 1VS1 classifiers are constructed for the confuse part by using the support vectors. During the class incremental learning process, the OCSVM of the new class is trained at first. Then the support vectors of the old classes and the support vectors of the new class are reused to train 1VS1 classifiers for the confuse part. In order to bring more information to the certain support vectors, the support vectors are at the boundary of the distribution of samples as much as possible when the OCSVM is built. Compared with the traditional methods, the proposed method retains the original model and thus reduces memory consumption and training time cost. Various experiments on different datasets also verify the efficiency of the proposed method.

HSI-CNN: A Novel Convolution Neural Network for Hyperspectral Image

With the development of deep learning, the performance of hyperspectral image (HSI) classification has been greatly improved in recent years. The shortage of training samples has become a bottleneck for further improvement of performance. In this paper, we propose a novel convolutional neural network framework for the characteristics of hyperspectral image data, called HSI-CNN. Firstly, the spectral-spatial feature is extracted from a target pixel and its neighbors. Then, a number of one-dimensional feature maps, obtained by convolution operation on spectral-spatial features, are stacked into a two-dimensional matrix. Finally, the two-dimensional matrix considered as an image is fed into standard CNN. This is why we call it HSI-CNN. In addition, we also implements two depth network classification models, called HSI-CNN+XGBoost and HSI-CapsNet, in order to compare the performance of our framework. Experiments show that the performance of hyperspectral image classification is improved efficiently with HSI-CNN framework. We evaluate the model's performance using four popular HSI datasets, which are the Kennedy Space Center (KSC), Indian Pines (IP), Pavia University scene (PU) and Salinas scene (SA). As far as we concerned, HSI-CNN has got the state-of-art accuracy among all methods we have known on these datasets of 99.28%, 99.09%, 99.42%, 98.95% separately.