Automatic Summarization of Doctor-Patient Encounter Dialogues Using Large Language Model through Prompt Tuning

Automatic text summarization (ATS) is an emerging technology to assist clinicians in providing continuous and coordinated care. This study presents an approach to summarize doctor-patient dialogues using generative large language models (LLMs). We developed prompt-tuning algorithms to instruct generative LLMs to summarize clinical text. We examined the prompt-tuning strategies, the size of soft prompts, and the few-short learning ability of GatorTronGPT, a generative clinical LLM developed using 277 billion clinical and general English words with up to 20 billion parameters. We compared GatorTronGPT with a previous solution based on fine-tuning of a widely used T5 model, using a clinical benchmark dataset MTS-DIALOG. The experimental results show that the GatorTronGPT- 20B model achieved the best performance on all evaluation metrics. The proposed solution has a low computing cost as the LLM parameters are not updated during prompt-tuning. This study demonstrates the efficiency of generative clinical LLMs for clinical ATS through prompt tuning.

Improving Generalizability of Extracting Social Determinants of Health Using Large Language Models through Prompt-tuning

The progress in natural language processing (NLP) using large language models (LLMs) has greatly improved patient information extraction from clinical narratives. However, most methods based on the fine-tuning strategy have limited transfer learning ability for cross-domain applications. This study proposed a novel approach that employs a soft prompt-based learning architecture, which introduces trainable prompts to guide LLMs toward desired outputs. We examined two types of LLM architectures, including encoder-only GatorTron and decoder-only GatorTronGPT, and evaluated their performance for the extraction of social determinants of health (SDoH) using a cross-institution dataset from the 2022 n2c2 challenge and a cross-disease dataset from the University of Florida (UF) Health. The results show that decoder-only LLMs with prompt tuning achieved better performance in cross-domain applications. GatorTronGPT achieved the best F1 scores for both datasets, outperforming traditional fine-tuned GatorTron by 8.9% and 21.8% in a cross-institution setting, and 5.5% and 14.5% in a cross-disease setting.

BAGS: Blur Agnostic Gaussian Splatting through Multi-Scale Kernel Modeling

Recent efforts in using 3D Gaussians for scene reconstruction and novel view synthesis can achieve impressive results on curated benchmarks; however, images captured in real life are often blurry. In this work, we analyze the robustness of Gaussian-Splatting-based methods against various image blur, such as motion blur, defocus blur, downscaling blur, \etc. Under these degradations, Gaussian-Splatting-based methods tend to overfit and produce worse results than Neural-Radiance-Field-based methods. To address this issue, we propose Blur Agnostic Gaussian Splatting (BAGS). BAGS introduces additional 2D modeling capacities such that a 3D-consistent and high quality scene can be reconstructed despite image-wise blur. Specifically, we model blur by estimating per-pixel convolution kernels from a Blur Proposal Network (BPN). BPN is designed to consider spatial, color, and depth variations of the scene to maximize modeling capacity. Additionally, BPN also proposes a quality-assessing mask, which indicates regions where blur occur. Finally, we introduce a coarse-to-fine kernel optimization scheme; this optimization scheme is fast and avoids sub-optimal solutions due to a sparse point cloud initialization, which often occurs when we apply Structure-from-Motion on blurry images. We demonstrate that BAGS achieves photorealistic renderings under various challenging blur conditions and imaging geometry, while significantly improving upon existing approaches.

Aria Everyday Activities Dataset

We present Aria Everyday Activities (AEA) Dataset, an egocentric multimodal open dataset recorded using Project Aria glasses. AEA contains 143 daily activity sequences recorded by multiple wearers in five geographically diverse indoor locations. Each of the recording contains multimodal sensor data recorded through the Project Aria glasses. In addition, AEA provides machine perception data including high frequency globally aligned 3D trajectories, scene point cloud, per-frame 3D eye gaze vector and time aligned speech transcription. In this paper, we demonstrate a few exemplar research applications enabled by this dataset, including neural scene reconstruction and prompted segmentation. AEA is an open source dataset that can be downloaded from https://www.projectaria.com/datasets/aea/. We are also providing open-source implementations and examples of how to use the dataset in Project Aria Tools https://github.com/facebookresearch/projectaria_tools.

Me LLaMA: Foundation Large Language Models for Medical Applications

Recent large language models (LLMs) like ChatGPT and LLaMA have shown great promise in many AI applications. However, their performance on medical tasks is suboptimal and can be further improved by training on large domain-specific datasets. This study introduces Me LLaMA, a medical LLM family including foundation models - Me LLaMA 13/70B and their chat-enhanced versions - Me LLaMA 13/70B-chat, developed through the continual pre-training and instruction tuning of LLaMA2 using large medical data. Our domain-specific data suite for training and evaluation, includes a large-scale continual pre-training dataset with 129B tokens, an instruction tuning dataset with 214k samples, and a medical evaluation benchmark (MIBE) across six tasks with 14 datasets. Our extensive evaluation using MIBE shows that Me LLaMA models surpass existing open-source medical LLMs in zero-shot and few-shot learning and outperform commercial giants like ChatGPT on 6 out of 8 datasets and GPT-4 in 3 out of 8 datasets. In addition, we empirically investigated the catastrophic forgetting problem, and our results show that Me LLaMA models outperform other medical LLMs. Me LLaMA is one of the first and largest open-source foundational LLMs designed for the medical domain, using both biomedical and clinical data. It exhibits superior performance across both general and medical tasks compared to other medical LLMs, rendering it an attractive choice for medical AI applications. All resources are available at: https://github.com/BIDS-Xu-Lab/Me-LLaMA.

CARAT: Contrastive Feature Reconstruction and Aggregation for Multi-modal Multi-label Emotion Recognition

Multi-modal multi-label emotion recognition (MMER) aims to identify relevant emotions from multiple modalities. The challenge of MMER is how to effectively capture discriminative features for multiple labels from heterogeneous data. Recent studies are mainly devoted to exploring various fusion strategies to integrate multi-modal information into a unified representation for all labels. However, such a learning scheme not only overlooks the specificity of each modality but also fails to capture individual discriminative features for different labels. Moreover, dependencies of labels and modalities cannot be effectively modeled. To address these issues, this paper presents ContrAstive feature Reconstruction and AggregaTion (CARAT) for the MMER task. Specifically, we devise a reconstruction-based fusion mechanism to better model fine-grained modality-to-label dependencies by contrastively learning modal-separated and label-specific features. To further exploit the modality complementarity, we introduce a shuffle-based aggregation strategy to enrich co-occurrence collaboration among labels. Experiments on two benchmark datasets CMU-MOSEI and M3ED demonstrate the effectiveness of CARAT over state-of-the-art methods. Code is available at https://github.com/chengzju/CARAT.

Generative Large Language Models Are All-purpose Text Analytics Engines: Text-to-text Learning Is All Your Need

Objective To solve major clinical natural language processing (NLP) tasks using a unified text-to-text learning architecture based on a generative large language model (LLM) via prompt tuning. Methods We formulated 7 key clinical NLP tasks as text-to-text learning and solved them using one unified generative clinical LLM, GatorTronGPT, developed using GPT-3 architecture and trained with up to 20 billion parameters. We adopted soft prompts (i.e., trainable vectors) with frozen LLM, where the LLM parameters were not updated (i.e., frozen) and only the vectors of soft prompts were updated, known as prompt tuning. We added additional soft prompts as a prefix to the input layer, which were optimized during the prompt tuning. We evaluated the proposed method using 7 clinical NLP tasks and compared them with previous task-specific solutions based on Transformer models. Results and Conclusion The proposed approach achieved state-of-the-art performance for 5 out of 7 major clinical NLP tasks using one unified generative LLM. Our approach outperformed previous task-specific transformer models by ~3% for concept extraction and 7% for relation extraction applied to social determinants of health, 3.4% for clinical concept normalization, 3.4~10% for clinical abbreviation disambiguation, and 5.5~9% for natural language inference. Our approach also outperformed a previously developed prompt-based machine reading comprehension (MRC) model, GatorTron-MRC, for clinical concept and relation extraction. The proposed approach can deliver the ``one model for all`` promise from training to deployment using a unified generative LLM.

GaitContour: Efficient Gait Recognition based on a Contour-Pose Representation

Gait recognition holds the promise to robustly identify subjects based on walking patterns instead of appearance information. In recent years, this field has been dominated by learning methods based on two principal input representations: dense silhouette masks or sparse pose keypoints. In this work, we propose a novel, point-based Contour-Pose representation, which compactly expresses both body shape and body parts information. We further propose a local-to-global architecture, called GaitContour, to leverage this novel representation and efficiently compute subject embedding in two stages. The first stage consists of a local transformer that extracts features from five different body regions. The second stage then aggregates the regional features to estimate a global human gait representation. Such a design significantly reduces the complexity of the attention operation and improves efficiency and performance simultaneously. Through large scale experiments, GaitContour is shown to perform significantly better than previous point-based methods, while also being significantly more efficient than silhouette-based methods. On challenging datasets with significant distractors, GaitContour can even outperform silhouette-based methods.

On the Impact of Cross-Domain Data on German Language Models

Traditionally, large language models have been either trained on general web crawls or domain-specific data. However, recent successes of generative large language models, have shed light on the benefits of cross-domain datasets. To examine the significance of prioritizing data diversity over quality, we present a German dataset comprising texts from five domains, along with another dataset aimed at containing high-quality data. Through training a series of models ranging between 122M and 750M parameters on both datasets, we conduct a comprehensive benchmark on multiple downstream tasks. Our findings demonstrate that the models trained on the cross-domain dataset outperform those trained on quality data alone, leading to improvements up to $4.45\%$ over the previous state-of-the-art. The models are available at https://huggingface.co/ikim-uk-essen