Assessing Multimodal Chronic Wound Embeddings with Expert Triplet Agreement

Recessive dystrophic epidermolysis bullosa (RDEB) is a rare genetic skin disorder for which clinicians greatly benefit from finding similar cases using images and clinical text. However, off-the-shelf foundation models do not reliably capture clinically meaningful features for this heterogeneous, long-tail disease, and structured measurement of agreement with experts is challenging. To address these gaps, we propose evaluating embedding spaces with expert ordinal comparisons (triplet judgments), which are fast to collect and encode implicit clinical similarity knowledge. We further introduce TriDerm, a multimodal framework that learns interpretable wound representations from small cohorts by integrating wound imagery, boundary masks, and expert reports. On the vision side, TriDerm adapts visual foundation models to RDEB using wound-level attention pooling and non-contrastive representation learning. For text, we prompt large language models with comparison queries and recover medically meaningful representations via soft ordinal embeddings (SOE). We show that visual and textual modalities capture complementary aspects of wound phenotype, and that fusing both modalities yields 73.5% agreement with experts, outperforming the best off-the-shelf single-modality foundation model by over 5.6 percentage points. We make the expert annotation tool, model code and representative dataset samples publicly available.

Effort-Based Criticality Metrics for Evaluating 3D Perception Errors in Autonomous Driving

Criticality metrics such as time-to-collision (TTC) quantify collision urgency but conflate the consequences of false-positive (FP) and false-negative (FN) perception errors. We propose two novel effort-based metrics: False Speed Reduction (FSR), the cumulative velocity loss from persistent phantom detections, and Maximum Deceleration Rate (MDR), the peak braking demand from missed objects under a constant-acceleration model. These longitudinal metrics are complemented by Lateral Evasion Acceleration (LEA), adapted from prior lateral evasion kinematics and coupled with reachability-based collision timing to quantify the minimum steering effort to avoid a predicted collision. A reachability-based ellipsoidal collision filter ensures only dynamically plausible threats are scored, with frame-level matching and track-level aggregation. Evaluation of different perception pipelines on nuScenes and Argoverse~2 shows that 65-93% of errors are non-critical, and Spearman correlation analysis confirms that all three metrics capture safety-relevant information inaccessible to established time-based, deceleration-based, or normalized criticality measures, enabling targeted mining of the most critical perception failures.

Spectral Alignment in Forward-Backward Representations via Temporal Abstraction

Forward-backward (FB) representations provide a powerful framework for learning the successor representation (SR) in continuous spaces by enforcing a low-rank factorization. However, a fundamental spectral mismatch often exists between the high-rank transition dynamics of continuous environments and the low-rank bottleneck of the FB architecture, making accurate low-rank representation learning difficult. In this work, we analyze temporal abstraction as a mechanism to mitigate this mismatch. By characterizing the spectral properties of the transition operator, we show that temporal abstraction acts as a low-pass filter that suppresses high-frequency spectral components. This suppression reduces the effective rank of the induced SR while preserving a formal bound on the resulting value function error. Empirically, we show that this alignment is a key factor for stable FB learning, particularly at high discount factors where bootstrapping becomes error-prone. Our results identify temporal abstraction as a principled mechanism for shaping the spectral structure of the underlying MDP and enabling effective long-horizon representations in continuous control.

Sparse3DTrack: Monocular 3D Object Tracking Using Sparse Supervision

Monocular 3D object tracking aims to estimate temporally consistent 3D object poses across video frames, enabling autonomous agents to reason about scene dynamics. However, existing state-of-the-art approaches are fully supervised and rely on dense 3D annotations over long video sequences, which are expensive to obtain and difficult to scale. In this work, we address this fundamental limitation by proposing the first sparsely supervised framework for monocular 3D object tracking. Our approach decomposes the task into two sequential sub-problems: 2D query matching and 3D geometry estimation. Both components leverage the spatio-temporal consistency of image sequences to augment a sparse set of labeled samples and learn rich 2D and 3D representations of the scene. Leveraging these learned cues, our model automatically generates high-quality 3D pseudolabels across entire videos, effectively transforming sparse supervision into dense 3D track annotations. This enables existing fully-supervised trackers to effectively operate under extreme label sparsity. Extensive experiments on the KITTI and nuScenes datasets demonstrate that our method significantly improves tracking performance, achieving an improvement of up to 15.50 p.p. while using at most four ground truth annotations per track.

ConfCtrl: Enabling Precise Camera Control in Video Diffusion via Confidence-Aware Interpolation

We address the challenge of novel view synthesis from only two input images under large viewpoint changes. Existing regression-based methods lack the capacity to reconstruct unseen regions, while camera-guided diffusion models often deviate from intended trajectories due to noisy point cloud projections or insufficient conditioning from camera poses. To address these issues, we propose ConfCtrl, a confidence-aware video interpolation framework that enables diffusion models to follow prescribed camera poses while completing unseen regions. ConfCtrl initializes the diffusion process by combining a confidence-weighted projected point cloud latent with noise as the conditioning input. It then applies a Kalman-inspired predict-update mechanism, treating the projected point cloud as a noisy measurement and using learned residual corrections to balance pose-driven predictions with noisy geometric observations. This allows the model to rely on reliable projections while down-weighting uncertain regions, yielding stable, geometry-aware generation. Experiments on multiple datasets show that ConfCtrl produces geometrically consistent and visually plausible novel views, effectively reconstructing occluded regions under large viewpoint changes.

Open-World Motion Forecasting

Motion forecasting aims to predict the future trajectories of dynamic agents in the scene, enabling autonomous vehicles to effectively reason about scene evolution. Existing approaches operate under the closed-world regime and assume fixed object taxonomy as well as access to high-quality perception. Therefore, they struggle in real-world settings where perception is imperfect and object taxonomy evolves over time. In this work, we bridge this fundamental gap by introducing open-world motion forecasting, a novel setting in which new object classes are sequentially introduced over time and future object trajectories are estimated directly from camera images. We tackle this setting by proposing the first end-to-end class-incremental motion forecasting framework to mitigate catastrophic forgetting while simultaneously learning to forecast newly introduced classes. When a new class is introduced, our framework employs a pseudo-labeling strategy to first generate motion forecasting pseudo-labels for all known classes which are then processed by a vision-language model to filter inconsistent and over-confident predictions. Parallelly, our approach further mitigates catastrophic forgetting by using a novel replay sampling strategy that leverages query feature variance to sample previous sequences with informative motion patterns. Extensive evaluation on the nuScenes and Argoverse 2 datasets demonstrates that our approach successfully resists catastrophic forgetting and maintains performance on previously learned classes while improving adaptation to novel ones. Further, we demonstrate that our approach supports zero-shot transfer to real-world driving and naturally extends to end-to-end class-incremental planning, enabling continual adaptation of the full autonomous driving system. We provide the code at https://omen.cs.uni-freiburg.de .

The Neural Compass: Probabilistic Relative Feature Fields for Robotic Search

Object co-occurrences provide a key cue for finding objects successfully and efficiently in unfamiliar environments. Typically, one looks for cups in kitchens and views fridges as evidence of being in a kitchen. Such priors have also been exploited in artificial agents, but they are typically learned from explicitly labeled data or queried from language models. It is still unclear whether these relations can be learned implicitly from unlabeled observations alone. In this work, we address this problem and propose ProReFF, a feature field model trained to predict relative distributions of features obtained from pre-trained vision language models. In addition, we introduce a learning-based strategy that enables training from unlabeled and potentially contradictory data by aligning inconsistent observations into a coherent relative distribution. For the downstream object search task, we propose an agent that leverages predicted feature distributions as a semantic prior to guide exploration toward regions with a high likelihood of containing the object. We present extensive evaluations demonstrating that ProReFF captures meaningful relative feature distributions in natural scenes and provides insight into the impact of our proposed alignment step. We further evaluate the performance of our search agent in 100 challenges in the Matterport3D simulator, comparing with feature-based baselines and human participants. The proposed agent is 20% more efficient than the strongest baseline and achieves up to 80% of human performance.

BLINK: Behavioral Latent Modeling of NK Cell Cytotoxicity

Machine learning models of cellular interaction dynamics hold promise for understanding cell behavior. Natural killer (NK) cell cytotoxicity is a prominent example of such interaction dynamics and is commonly studied using time-resolved multi-channel fluorescence microscopy. Although tumor cell death events can be annotated at single frames, NK cytotoxic outcome emerges over time from cellular interactions and cannot be reliably inferred from frame-wise classification alone. We introduce BLINK, a trajectory-based recurrent state-space model that serves as a cell world model for NK-tumor interactions. BLINK learns latent interaction dynamics from partially observed NK-tumor interaction sequences and predicts apoptosis increments that accumulate into cytotoxic outcomes. Experiments on long-term time-lapse NK-tumor recordings show improved cytotoxic outcome detection and enable forecasting of future outcomes, together with an interpretable latent representation that organizes NK trajectories into coherent behavioral modes and temporally structured interaction phases. BLINK provides a unified framework for quantitative evaluation and structured modeling of NK cytotoxic behavior at the single-cell level.

Embedding interpretable $\ell_1$-regression into neural networks for uncovering temporal structure in cell imaging

While artificial neural networks excel in unsupervised learning of non-sparse structure, classical statistical regression techniques offer better interpretability, in particular when sparseness is enforced by $\ell_1$ regularization, enabling identification of which factors drive observed dynamics. We investigate how these two types of approaches can be optimally combined, exemplarily considering two-photon calcium imaging data where sparse autoregressive dynamics are to be extracted. We propose embedding a vector autoregressive (VAR) model as an interpretable regression technique into a convolutional autoencoder, which provides dimension reduction for tractable temporal modeling. A skip connection separately addresses non-sparse static spatial information, selectively channeling sparse structure into the $\ell_1$-regularized VAR. $\ell_1$-estimation of regression parameters is enabled by differentiating through the piecewise linear solution path. This is contrasted with approaches where the autoencoder does not adapt to the VAR model. Having an embedded statistical model also enables a testing approach for comparing temporal sequences from the same observational unit. Additionally, contribution maps visualize which spatial regions drive the learned dynamics.

LAD-Drive: Bridging Language and Trajectory with Action-Aware Diffusion Transformers

While multimodal large language models (MLLMs) provide advanced reasoning for autonomous driving, translating their discrete semantic knowledge into continuous trajectories remains a fundamental challenge. Existing methods often rely on unimodal planning heads that inherently limit their ability to represent multimodal driving behavior. Furthermore, most generative approaches frequently condition on one-hot encoded actions, discarding the nuanced navigational uncertainty critical for complex scenarios. To resolve these limitations, we introduce LAD-Drive, a generative framework that structurally disentangles high-level intention from low-level spatial planning. LAD-Drive employs an action decoder to infer a probabilistic meta-action distribution, establishing an explicit belief state that preserves the nuanced intent typically lost by one-hot encodings. This distribution, fused with the vehicle's kinematic state, conditions an action-aware diffusion decoder that utilizes a truncated denoising process to refine learned motion anchors into safe, kinematically feasible trajectories. Extensive evaluations on the LangAuto benchmark demonstrate that LAD-Drive achieves state-of-the-art results, outperforming competitive baselines by up to 59% in Driving Score while significantly reducing route deviations and collisions. We will publicly release the code and models on https://github.com/iis-esslingen/lad-drive.