EVD Surgical Guidance with Retro-Reflective Tool Tracking and Spatial Reconstruction using Head-Mounted Augmented Reality Device

Augmented Reality (AR) has been used to facilitate surgical guidance during External Ventricular Drain (EVD) surgery, reducing the risks of misplacement in manual operations. During this procedure, the key challenge is accurately estimating the spatial relationship between pre-operative images and actual patient anatomy in AR environment. This research proposes a novel framework utilizing Time of Flight (ToF) depth sensors integrated in commercially available AR Head Mounted Devices (HMD) for precise EVD surgical guidance. As previous studies have proven depth errors for ToF sensors, we first assessed their properties on AR-HMDs. Subsequently, a depth error model and patient-specific parameter identification method are introduced for accurate surface information. A tracking pipeline combining retro-reflective markers and point clouds is then proposed for accurate head tracking. The head surface is reconstructed using depth data for spatial registration, avoiding fixing tracking targets rigidly on the patient's skull. Firstly, $7.580\pm 1.488 mm$ depth value error was revealed on human skin, indicating the significance of depth correction. Our results showed that the error was reduced by over $85\%$ using proposed depth correction method on head phantoms in different materials. Meanwhile, the head surface reconstructed with corrected depth data achieved sub-millimetre accuracy. An experiment on sheep head revealed $0.79 mm$ reconstruction error. Furthermore, a user study was conducted for the performance in simulated EVD surgery, where five surgeons performed nine k-wire injections on a head phantom with virtual guidance. Results of this study revealed $2.09 \pm 0.16 mm$ translational accuracy and $2.97\pm 0.91$ degree orientational accuracy.

Iterative Zero-Shot LLM Prompting for Knowledge Graph Construction

In the current digitalization era, capturing and effectively representing knowledge is crucial in most real-world scenarios. In this context, knowledge graphs represent a potent tool for retrieving and organizing a vast amount of information in a properly interconnected and interpretable structure. However, their generation is still challenging and often requires considerable human effort and domain expertise, hampering the scalability and flexibility across different application fields. This paper proposes an innovative knowledge graph generation approach that leverages the potential of the latest generative large language models, such as GPT-3.5, that can address all the main critical issues in knowledge graph building. The approach is conveyed in a pipeline that comprises novel iterative zero-shot and external knowledge-agnostic strategies in the main stages of the generation process. Our unique manifold approach may encompass significant benefits to the scientific community. In particular, the main contribution can be summarized by: (i) an innovative strategy for iteratively prompting large language models to extract relevant components of the final graph; (ii) a zero-shot strategy for each prompt, meaning that there is no need for providing examples for "guiding" the prompt result; (iii) a scalable solution, as the adoption of LLMs avoids the need for any external resources or human expertise. To assess the effectiveness of our proposed model, we performed experiments on a dataset that covered a specific domain. We claim that our proposal is a suitable solution for scalable and versatile knowledge graph construction and may be applied to different and novel contexts.

ImDiffusion: Imputed Diffusion Models for Multivariate Time Series Anomaly Detection

Anomaly detection in multivariate time series data is of paramount importance for ensuring the efficient operation of large-scale systems across diverse domains. However, accurately detecting anomalies in such data poses significant challenges. Existing approaches, including forecasting and reconstruction-based methods, struggle to address these challenges effectively. To overcome these limitations, we propose a novel anomaly detection framework named ImDiffusion, which combines time series imputation and diffusion models to achieve accurate and robust anomaly detection. The imputation-based approach employed by ImDiffusion leverages the information from neighboring values in the time series, enabling precise modeling of temporal and inter-correlated dependencies, reducing uncertainty in the data, thereby enhancing the robustness of the anomaly detection process. ImDiffusion further leverages diffusion models as time series imputers to accurately capturing complex dependencies. We leverage the step-by-step denoised outputs generated during the inference process to serve as valuable signals for anomaly prediction, resulting in improved accuracy and robustness of the detection process. We evaluate the performance of ImDiffusion via extensive experiments on benchmark datasets. The results demonstrate that our proposed framework significantly outperforms state-of-the-art approaches in terms of detection accuracy and timeliness. ImDiffusion is further integrated into the real production system in Microsoft and observe a remarkable 11.4% increase in detection F1 score compared to the legacy approach. To the best of our knowledge, ImDiffusion represents a pioneering approach that combines imputation-based techniques with time series anomaly detection, while introducing the novel use of diffusion models to the field.

From ChatGPT to ThreatGPT: Impact of Generative AI in Cybersecurity and Privacy

Undoubtedly, the evolution of Generative AI (GenAI) models has been the highlight of digital transformation in the year 2022. As the different GenAI models like ChatGPT and Google Bard continue to foster their complexity and capability, it's critical to understand its consequences from a cybersecurity perspective. Several instances recently have demonstrated the use of GenAI tools in both the defensive and offensive side of cybersecurity, and focusing on the social, ethical and privacy implications this technology possesses. This research paper highlights the limitations, challenges, potential risks, and opportunities of GenAI in the domain of cybersecurity and privacy. The work presents the vulnerabilities of ChatGPT, which can be exploited by malicious users to exfiltrate malicious information bypassing the ethical constraints on the model. This paper demonstrates successful example attacks like Jailbreaks, reverse psychology, and prompt injection attacks on the ChatGPT. The paper also investigates how cyber offenders can use the GenAI tools in developing cyber attacks, and explore the scenarios where ChatGPT can be used by adversaries to create social engineering attacks, phishing attacks, automated hacking, attack payload generation, malware creation, and polymorphic malware. This paper then examines defense techniques and uses GenAI tools to improve security measures, including cyber defense automation, reporting, threat intelligence, secure code generation and detection, attack identification, developing ethical guidelines, incidence response plans, and malware detection. We will also discuss the social, legal, and ethical implications of ChatGPT. In conclusion, the paper highlights open challenges and future directions to make this GenAI secure, safe, trustworthy, and ethical as the community understands its cybersecurity impacts.

ViP: A Differentially Private Foundation Model for Computer Vision

Artificial intelligence (AI) has seen a tremendous surge in capabilities thanks to the use of foundation models trained on internet-scale data. On the flip side, the uncurated nature of internet-scale data also poses significant privacy and legal risks, as they often contain personal information or copyrighted material that should not be trained on without permission. In this work, we propose as a mitigation measure a recipe to train foundation vision models with differential privacy (DP) guarantee. We identify masked autoencoders as a suitable learning algorithm that aligns well with DP-SGD, and train ViP -- a Vision transformer with differential Privacy -- under a strict privacy budget of $\epsilon=8$ on the LAION400M dataset. We evaluate the quality of representation learned by ViP using standard downstream vision tasks; in particular, ViP achieves a (non-private) linear probing accuracy of $55.7\%$ on ImageNet, comparable to that of end-to-end trained AlexNet (trained and evaluated on ImageNet). Our result suggests that scaling to internet-scale data can be practical for private learning. Code is available at \url{https://github.com/facebookresearch/ViP-MAE}.

RSPrompter: Learning to Prompt for Remote Sensing Instance Segmentation based on Visual Foundation Model

Leveraging vast training data (SA-1B), the foundation Segment Anything Model (SAM) proposed by Meta AI Research exhibits remarkable generalization and zero-shot capabilities. Nonetheless, as a category-agnostic instance segmentation method, SAM heavily depends on prior manual guidance involving points, boxes, and coarse-grained masks. Additionally, its performance on remote sensing image segmentation tasks has yet to be fully explored and demonstrated. In this paper, we consider designing an automated instance segmentation approach for remote sensing images based on the SAM foundation model, incorporating semantic category information. Inspired by prompt learning, we propose a method to learn the generation of appropriate prompts for SAM input. This enables SAM to produce semantically discernible segmentation results for remote sensing images, which we refer to as RSPrompter. We also suggest several ongoing derivatives for instance segmentation tasks, based on recent developments in the SAM community, and compare their performance with RSPrompter. Extensive experimental results on the WHU building, NWPU VHR-10, and SSDD datasets validate the efficacy of our proposed method. Our code is accessible at \url{https://kyanchen.github.io/RSPrompter}.

Stone Needle: A General Multimodal Large-scale Model Framework towards Healthcare

In healthcare, multimodal data is prevalent and requires to be comprehensively analyzed before diagnostic decisions, including medical images, clinical reports, etc. However, current large-scale artificial intelligence models predominantly focus on single-modal cognitive abilities and neglect the integration of multiple modalities. Therefore, we propose Stone Needle, a general multimodal large-scale model framework tailored explicitly for healthcare applications. Stone Needle serves as a comprehensive medical multimodal model foundation, integrating various modalities such as text, images, videos, and audio to surpass the limitations of single-modal systems. Through the framework components of intent analysis, medical foundation models, prompt manager, and medical language module, our architecture can perform multi-modal interaction in multiple rounds of dialogue. Our method is a general multimodal large-scale model framework, integrating diverse modalities and allowing us to tailor for specific tasks. The experimental results demonstrate the superior performance of our method compared to single-modal systems. The fusion of different modalities and the ability to process complex medical information in Stone Needle benefits accurate diagnosis, treatment recommendations, and patient care.

Multi-Site Clinical Federated Learning using Recursive and Attentive Models and NVFlare

The prodigious growth of digital health data has precipitated a mounting interest in harnessing machine learning methodologies, such as natural language processing (NLP), to scrutinize medical records, clinical notes, and other text-based health information. Although NLP techniques have exhibited substantial potential in augmenting patient care and informing clinical decision-making, data privacy and adherence to regulations persist as critical concerns. Federated learning (FL) emerges as a viable solution, empowering multiple organizations to train machine learning models collaboratively without disseminating raw data. This paper proffers a pragmatic approach to medical NLP by amalgamating FL, NLP models, and the NVFlare framework, developed by NVIDIA. We introduce two exemplary NLP models, the Long-Short Term Memory (LSTM)-based model and Bidirectional Encoder Representations from Transformers (BERT), which have demonstrated exceptional performance in comprehending context and semantics within medical data. This paper encompasses the development of an integrated framework that addresses data privacy and regulatory compliance challenges while maintaining elevated accuracy and performance, incorporating BERT pretraining, and comprehensively substantiating the efficacy of the proposed approach.

Low-Confidence Samples Mining for Semi-supervised Object Detection

Reliable pseudo-labels from unlabeled data play a key role in semi-supervised object detection (SSOD). However, the state-of-the-art SSOD methods all rely on pseudo-labels with high confidence, which ignore valuable pseudo-labels with lower confidence. Additionally, the insufficient excavation for unlabeled data results in an excessively low recall rate thus hurting the network training. In this paper, we propose a novel Low-confidence Samples Mining (LSM) method to utilize low-confidence pseudo-labels efficiently. Specifically, we develop an additional pseudo information mining (PIM) branch on account of low-resolution feature maps to extract reliable large-area instances, the IoUs of which are higher than small-area ones. Owing to the complementary predictions between PIM and the main branch, we further design self-distillation (SD) to compensate for both in a mutually-learning manner. Meanwhile, the extensibility of the above approaches enables our LSM to apply to Faster-RCNN and Deformable-DETR respectively. On the MS-COCO benchmark, our method achieves 3.54% mAP improvement over state-of-the-art methods under 5% labeling ratios.

Neural network analysis of neutron and X-ray reflectivity data: Incorporating prior knowledge for tackling the phase problem

Due to the lack of phase information, determining the physical parameters of multilayer thin films from measured neutron and X-ray reflectivity curves is, on a fundamental level, an underdetermined inverse problem. This so-called phase problem poses limitations on standard neural networks, constraining the range and number of considered parameters in previous machine learning solutions. To overcome this, we present an approach that utilizes prior knowledge to regularize the training process over larger parameter spaces. We demonstrate the effectiveness of our method in various scenarios, including multilayer structures with box model parameterization and a physics-inspired special parameterization of the scattering length density profile for a multilayer structure. By leveraging the input of prior knowledge, we can improve the training dynamics and address the underdetermined ("ill-posed") nature of the problem. In contrast to previous methods, our approach scales favorably when increasing the complexity of the inverse problem, working properly even for a 5-layer multilayer model and an N-layer periodic multilayer model with up to 17 open parameters.