Enhancing Synthetic CT from CBCT via Multimodal Fusion: A Study on the Impact of CBCT Quality and Alignment

Cone-Beam Computed Tomography (CBCT) is widely used for real-time intraoperative imaging due to its low radiation dose and high acquisition speed. However, despite its high resolution, CBCT suffers from significant artifacts and thereby lower visual quality, compared to conventional Computed Tomography (CT). A recent approach to mitigate these artifacts is synthetic CT (sCT) generation, translating CBCT volumes into the CT domain. In this work, we enhance sCT generation through multimodal learning, integrating intraoperative CBCT with preoperative CT. Beyond validation on two real-world datasets, we use a versatile synthetic dataset, to analyze how CBCT-CT alignment and CBCT quality affect sCT quality. The results demonstrate that multimodal sCT consistently outperform unimodal baselines, with the most significant gains observed in well-aligned, low-quality CBCT-CT cases. Finally, we demonstrate that these findings are highly reproducible in real-world clinical datasets.

Feature-Based Lie Group Transformer for Real-World Applications

The main goal of representation learning is to acquire meaningful representations from real-world sensory inputs without supervision. Representation learning explains some aspects of human development. Various neural network (NN) models have been proposed that acquire empirically good representations. However, the formulation of a good representation has not been established. We recently proposed a method for categorizing changes between a pair of sensory inputs. A unique feature of this approach is that transformations between two sensory inputs are learned to satisfy algebraic structural constraints. Conventional representation learning often assumes that disentangled independent feature axes is a good representation; however, we found that such a representation cannot account for conditional independence. To overcome this problem, we proposed a new method using group decomposition in Galois algebra theory. Although this method is promising for defining a more general representation, it assumes pixel-to-pixel translation without feature extraction, and can only process low-resolution images with no background, which prevents real-world application. In this study, we provide a simple method to apply our group decomposition theory to a more realistic scenario by combining feature extraction and object segmentation. We replace pixel translation with feature translation and formulate object segmentation as grouping features under the same transformation. We validated the proposed method on a practical dataset containing both real-world object and background. We believe that our model will lead to a better understanding of human development of object recognition in the real world.

Paired and Unpaired Image to Image Translation using Generative Adversarial Networks

Image to image translation is an active area of research in the field of computer vision, enabling the generation of new images with different styles, textures, or resolutions while preserving their characteristic properties. Recent architectures leverage Generative Adversarial Networks (GANs) to transform input images from one domain to another. In this work, we focus on the study of both paired and unpaired image translation across multiple image domains. For the paired task, we used a conditional GAN model, and for the unpaired task, we trained it using cycle consistency loss. We experimented with different types of loss functions, multiple Patch-GAN sizes, and model architectures. New quantitative metrics - precision, recall, and FID score - were used for analysis. In addition, a qualitative study of the results of different experiments was conducted.

Generalist Models in Medical Image Segmentation: A Survey and Performance Comparison with Task-Specific Approaches

Following the successful paradigm shift of large language models, leveraging pre-training on a massive corpus of data and fine-tuning on different downstream tasks, generalist models have made their foray into computer vision. The introduction of Segment Anything Model (SAM) set a milestone on segmentation of natural images, inspiring the design of a multitude of architectures for medical image segmentation. In this survey we offer a comprehensive and in-depth investigation on generalist models for medical image segmentation. We start with an introduction on the fundamentals concepts underpinning their development. Then, we provide a taxonomy on the different declinations of SAM in terms of zero-shot, few-shot, fine-tuning, adapters, on the recent SAM 2, on other innovative models trained on images alone, and others trained on both text and images. We thoroughly analyze their performances at the level of both primary research and best-in-literature, followed by a rigorous comparison with the state-of-the-art task-specific models. We emphasize the need to address challenges in terms of compliance with regulatory frameworks, privacy and security laws, budget, and trustworthy artificial intelligence (AI). Finally, we share our perspective on future directions concerning synthetic data, early fusion, lessons learnt from generalist models in natural language processing, agentic AI and physical AI, and clinical translation.

RoboSwap: A GAN-driven Video Diffusion Framework For Unsupervised Robot Arm Swapping

Recent advancements in generative models have revolutionized video synthesis and editing. However, the scarcity of diverse, high-quality datasets continues to hinder video-conditioned robotic learning, limiting cross-platform generalization. In this work, we address the challenge of swapping a robotic arm in one video with another: a key step for crossembodiment learning. Unlike previous methods that depend on paired video demonstrations in the same environmental settings, our proposed framework, RoboSwap, operates on unpaired data from diverse environments, alleviating the data collection needs. RoboSwap introduces a novel video editing pipeline integrating both GANs and diffusion models, combining their isolated advantages. Specifically, we segment robotic arms from their backgrounds and train an unpaired GAN model to translate one robotic arm to another. The translated arm is blended with the original video background and refined with a diffusion model to enhance coherence, motion realism and object interaction. The GAN and diffusion stages are trained independently. Our experiments demonstrate that RoboSwap outperforms state-of-the-art video and image editing models on three benchmarks in terms of both structural coherence and motion consistency, thereby offering a robust solution for generating reliable, cross-embodiment data in robotic learning.

Segmenting France Across Four Centuries

Historical maps offer an invaluable perspective into territory evolution across past centuries--long before satellite or remote sensing technologies existed. Deep learning methods have shown promising results in segmenting historical maps, but publicly available datasets typically focus on a single map type or period, require extensive and costly annotations, and are not suited for nationwide, long-term analyses. In this paper, we introduce a new dataset of historical maps tailored for analyzing large-scale, long-term land use and land cover evolution with limited annotations. Spanning metropolitan France (548,305 km^2), our dataset contains three map collections from the 18th, 19th, and 20th centuries. We provide both comprehensive modern labels and 22,878 km^2 of manually annotated historical labels for the 18th and 19th century maps. Our dataset illustrates the complexity of the segmentation task, featuring stylistic inconsistencies, interpretive ambiguities, and significant landscape changes (e.g., marshlands disappearing in favor of forests). We assess the difficulty of these challenges by benchmarking three approaches: a fully-supervised model trained with historical labels, and two weakly-supervised models that rely only on modern annotations. The latter either use the modern labels directly or first perform image-to-image translation to address the stylistic gap between historical and contemporary maps. Finally, we discuss how these methods can support long-term environment monitoring, offering insights into centuries of landscape transformation. Our official project repository is publicly available at https://github.com/Archiel19/FRAx4.git.

Moment kernels: a simple and scalable approach for equivariance to rotations and reflections in deep convolutional networks

The principle of translation equivariance (if an input image is translated an output image should be translated by the same amount), led to the development of convolutional neural networks that revolutionized machine vision. Other symmetries, like rotations and reflections, play a similarly critical role, especially in biomedical image analysis, but exploiting these symmetries has not seen wide adoption. We hypothesize that this is partially due to the mathematical complexity of methods used to exploit these symmetries, which often rely on representation theory, a bespoke concept in differential geometry and group theory. In this work, we show that the same equivariance can be achieved using a simple form of convolution kernels that we call ``moment kernels,'' and prove that all equivariant kernels must take this form. These are a set of radially symmetric functions of a spatial position $x$, multiplied by powers of the components of $x$ or the identity matrix. We implement equivariant neural networks using standard convolution modules, and provide architectures to execute several biomedical image analysis tasks that depend on equivariance principles: classification (outputs are invariant under orthogonal transforms), 3D image registration (outputs transform like a vector), and cell segmentation (quadratic forms defining ellipses transform like a matrix).

Image-to-Image Translation with Diffusion Transformers and CLIP-Based Image Conditioning

Image-to-image translation aims to learn a mapping between a source and a target domain, enabling tasks such as style transfer, appearance transformation, and domain adaptation. In this work, we explore a diffusion-based framework for image-to-image translation by adapting Diffusion Transformers (DiT), which combine the denoising capabilities of diffusion models with the global modeling power of transformers. To guide the translation process, we condition the model on image embeddings extracted from a pre-trained CLIP encoder, allowing for fine-grained and structurally consistent translations without relying on text or class labels. We incorporate both a CLIP similarity loss to enforce semantic consistency and an LPIPS perceptual loss to enhance visual fidelity during training. We validate our approach on two benchmark datasets: face2comics, which translates real human faces to comic-style illustrations, and edges2shoes, which translates edge maps to realistic shoe images. Experimental results demonstrate that DiT, combined with CLIP-based conditioning and perceptual similarity objectives, achieves high-quality, semantically faithful translations, offering a promising alternative to GAN-based models for paired image-to-image translation tasks.

Training Free Stylized Abstraction

Stylized abstraction synthesizes visually exaggerated yet semantically faithful representations of subjects, balancing recognizability with perceptual distortion. Unlike image-to-image translation, which prioritizes structural fidelity, stylized abstraction demands selective retention of identity cues while embracing stylistic divergence, especially challenging for out-of-distribution individuals. We propose a training-free framework that generates stylized abstractions from a single image using inference-time scaling in vision-language models (VLLMs) to extract identity-relevant features, and a novel cross-domain rectified flow inversion strategy that reconstructs structure based on style-dependent priors. Our method adapts structural restoration dynamically through style-aware temporal scheduling, enabling high-fidelity reconstructions that honor both subject and style. It supports multi-round abstraction-aware generation without fine-tuning. To evaluate this task, we introduce StyleBench, a GPT-based human-aligned metric suited for abstract styles where pixel-level similarity fails. Experiments across diverse abstraction (e.g., LEGO, knitted dolls, South Park) show strong generalization to unseen identities and styles in a fully open-source setup.

MT$^{3}$: Scaling MLLM-based Text Image Machine Translation via Multi-Task Reinforcement Learning

Text Image Machine Translation (TIMT)-the task of translating textual content embedded in images-is critical for applications in accessibility, cross-lingual information access, and real-world document understanding. However, TIMT remains a complex challenge due to the need for accurate optical character recognition (OCR), robust visual-text reasoning, and high-quality translation, often requiring cascading multi-stage pipelines. Recent advances in large-scale Reinforcement Learning (RL) have improved reasoning in Large Language Models (LLMs) and Multimodal LLMs (MLLMs), but their application to end-to-end TIMT is still underexplored. To bridge this gap, we introduce MT$^{3}$, the first framework to apply Multi-Task RL to MLLMs for end-to-end TIMT. MT$^{3}$ adopts a multi-task optimization paradigm targeting three key sub-skills: text recognition, context-aware reasoning, and translation. It is trained using a novel multi-mixed reward mechanism that adapts rule-based RL strategies to TIMT's intricacies, offering fine-grained, non-binary feedback across tasks. Furthermore, to facilitate the evaluation of TIMT in authentic cross-cultural and real-world social media contexts, we introduced XHSPost, the first social media TIMT benchmark. Our MT$^{3}$-7B-Zero achieves state-of-the-art results on the latest in-domain MIT-10M benchmark, outperforming strong baselines such as Qwen2.5-VL-72B and InternVL2.5-78B by notable margins across multiple metrics. Additionally, the model shows strong generalization to out-of-distribution language pairs and datasets. In-depth analyses reveal how multi-task synergy, reinforcement learning initialization, curriculum design, and reward formulation contribute to advancing MLLM-driven TIMT.