Generalist Models in Medical Image Segmentation: A Survey and Performance Comparison with Task-Specific Approaches

Following the successful paradigm shift of large language models, leveraging pre-training on a massive corpus of data and fine-tuning on different downstream tasks, generalist models have made their foray into computer vision. The introduction of Segment Anything Model (SAM) set a milestone on segmentation of natural images, inspiring the design of a multitude of architectures for medical image segmentation. In this survey we offer a comprehensive and in-depth investigation on generalist models for medical image segmentation. We start with an introduction on the fundamentals concepts underpinning their development. Then, we provide a taxonomy on the different declinations of SAM in terms of zero-shot, few-shot, fine-tuning, adapters, on the recent SAM 2, on other innovative models trained on images alone, and others trained on both text and images. We thoroughly analyze their performances at the level of both primary research and best-in-literature, followed by a rigorous comparison with the state-of-the-art task-specific models. We emphasize the need to address challenges in terms of compliance with regulatory frameworks, privacy and security laws, budget, and trustworthy artificial intelligence (AI). Finally, we share our perspective on future directions concerning synthetic data, early fusion, lessons learnt from generalist models in natural language processing, agentic AI and physical AI, and clinical translation.

Back to the Future: GNN-based NO$_2$ Forecasting via Future Covariates

Due to the latest environmental concerns in keeping at bay contaminants emissions in urban areas, air pollution forecasting has been rising the forefront of all researchers around the world. When predicting pollutant concentrations, it is common to include the effects of environmental factors that influence these concentrations within an extended period, like traffic, meteorological conditions and geographical information. Most of the existing approaches exploit this information as past covariates, i.e., past exogenous variables that affected the pollutant but were not affected by it. In this paper, we present a novel forecasting methodology to predict NO$_2$ concentration via both past and future covariates. Future covariates are represented by weather forecasts and future calendar events, which are already known at prediction time. In particular, we deal with air quality observations in a city-wide network of ground monitoring stations, modeling the data structure and estimating the predictions with a Spatiotemporal Graph Neural Network (STGNN). We propose a conditioning block that embeds past and future covariates into the current observations. After extracting meaningful spatiotemporal representations, these are fused together and projected into the forecasting horizon to generate the final prediction. To the best of our knowledge, it is the first time that future covariates are included in time series predictions in a structured way. Remarkably, we find that conditioning on future weather information has a greater impact than considering past traffic conditions. We release our code implementation at https://github.com/polimi-ispl/MAGCRN.

Super-Resolution of BVOC Emission Maps Via Domain Adaptation

Enhancing the resolution of Biogenic Volatile Organic Compound (BVOC) emission maps is a critical task in remote sensing. Recently, some Super-Resolution (SR) methods based on Deep Learning (DL) have been proposed, leveraging data from numerical simulations for their training process. However, when dealing with data derived from satellite observations, the reconstruction is particularly challenging due to the scarcity of measurements to train SR algorithms with. In our work, we aim at super-resolving low resolution emission maps derived from satellite observations by leveraging the information of emission maps obtained through numerical simulations. To do this, we combine a SR method based on DL with Domain Adaptation (DA) techniques, harmonizing the different aggregation strategies and spatial information used in simulated and observed domains to ensure compatibility. We investigate the effectiveness of DA strategies at different stages by systematically varying the number of simulated and observed emissions used, exploring the implications of data scarcity on the adaptation strategies. To the best of our knowledge, there are no prior investigations of DA in satellite-derived BVOC maps enhancement. Our work represents a first step toward the development of robust strategies for the reconstruction of observed BVOC emissions.

Multi-BVOC Super-Resolution Exploiting Compounds Inter-Connection

Biogenic Volatile Organic Compounds (BVOCs) emitted from the terrestrial ecosystem into the Earth's atmosphere are an important component of atmospheric chemistry. Due to the scarcity of measurement, a reliable enhancement of BVOCs emission maps can aid in providing denser data for atmospheric chemical, climate, and air quality models. In this work, we propose a strategy to super-resolve coarse BVOC emission maps by simultaneously exploiting the contributions of different compounds. To this purpose, we first accurately investigate the spatial inter-connections between several BVOC species. Then, we exploit the found similarities to build a Multi-Image Super-Resolution (MISR) system, in which a number of emission maps associated with diverse compounds are aggregated to boost Super-Resolution (SR) performance. We compare different configurations regarding the species and the number of joined BVOCs. Our experimental results show that incorporating BVOCs' relationship into the process can substantially improve the accuracy of the super-resolved maps. Interestingly, the best results are achieved when we aggregate the emission maps of strongly uncorrelated compounds. This peculiarity seems to confirm what was already guessed for other data-domains, i.e., joined uncorrelated information are more helpful than correlated ones to boost MISR performance. Nonetheless, the proposed work represents the first attempt in SR of BVOC emissions through the fusion of multiple different compounds.

Enhancing Biogenic Emission Maps Using Deep Learning

Biogenic Volatile Organic Compounds (BVOCs) play a critical role in biosphere-atmosphere interactions, being a key factor in the physical and chemical properties of the atmosphere and climate. Acquiring large and fine-grained BVOC emission maps is expensive and time-consuming, so most of the available BVOC data are obtained on a loose and sparse sampling grid or on small regions. However, high-resolution BVOC data are desirable in many applications, such as air quality, atmospheric chemistry, and climate monitoring. In this work, we propose to investigate the possibility of enhancing BVOC acquisitions, taking a step forward in explaining the relationships between plants and these compounds. We do so by comparing the performances of several state-of-the-art neural networks proposed for Single-Image Super-Resolution (SISR), showing how to adapt them to correctly handle emission data through preprocessing. Moreover, we also consider realistic scenarios, considering both temporal and geographical constraints. Finally, we present possible future developments in terms of Super-Resolution (SR) generalization, considering the scale-invariance property and super-resolving emissions from unseen compounds.