Cross-modal alignment (CA) and cross-modal prediction (CP) are the dominant paradigms for multimodal representation learning, yet there is no systematic understanding of when each succeeds, when each fails, and when cross-modal training helps at all -- a gap that leaves practitioners, especially in scientific domains like biomedicine or astrophysics, with heterogeneous instruments and multiple levels of organization and measurement, unable to diagnose why standard methods underperform the best single modality. We develop a unified linear framework that addresses both questions. Under a spiked signal-plus-noise model with structured cross-modal nuisance correlation, we derive separation ratios for both objectives that expose complementary failure modes: alignment whitens each modality and fails when nuisance is strongly correlated across views; prediction encodes whatever is cross-predictable through a one-sided whitening, with recovery governed by source-modality quality. The resulting phase diagram partitions multimodal problems into four regimes: Both, CA only, CP only, and Neither. We present a data-driven procedure to locate real-world datasets in this diagram using a small labeled subsample, identifying the preferred objective and prediction direction before any cross-modal training. Experiments on synthetic data, stereo-vision benchmarks, image-caption pairs, and real astrophysical data validate the predictions in the nonlinear regime, including the Neither regime where cross-modal training is actively harmful. Our framework lets practitioners diagnose their multimodal problem and choose the right objective before committing to training. Code to reproduce the results is available at https://github.com/IlayMalinyak/mm_align_vs_pred.
This paper introduces ARM, a discrete representation-based AutoRegressive Model that unifies image understanding, generation, and editing within a next-token prediction framework. ARM is built on three efforts: first, we train a discrete semantic visual tokenizer that maps images into compact token sequences. Our tokenizer is supervised with multiple objectives that jointly promote semantic discriminability, language alignment and faithful reconstruction, thereby supporting diverse tasks in a shared latent space. With this, we train a 7B autoregressive model over large-scale text and image token sequences, seamlessly developing vision-language perception and generation capabilities. Finally, to further improve preference-aligned behavior for text-to-image generation and instruction-guided editing, ARM applies reinforcement learning (RL) to optimize task-level objectives such as visual quality, instruction adherence, and edit consistency. Surprisingly, the results show that RL not only substantially improves performance on the target tasks (e.g., raising WISE overall from 0.50 to 0.56, GEdit-Bench-EN G_O from 5.75 to 6.68), but also induces cross-task synergy between text-to-image generation and editing. Collectively, these findings highlight autoregressive modeling, when paired with strong representations and preference optimization, as a scalable foundation for multimodal intelligence. Code: https://github.com/wdrink/ARM.
Low-light video enhancement (LLVE) remains a challenging task due to severe information degradation under low-illumination conditions. Recent multimodal approaches have significantly improved enhancement performance by incorporating auxiliary modalities, such as event streams and infrared images. However, these methods typically assume the availability of these modalities at inference, which is often not feasible in real-world scenarios. To solve this problem, in this work, we propose AMNet, a unified multimodal framework for LLVE, to support flexible modality-agnostic inference, where auxiliary modalities may be unavailable. To address the issue of modality absence, we introduce a Spatial-Spectral Dual-Gated Translator that learns the correspondence between auxiliary modalities and RGB inputs, producing implicit auxiliary representations to support the robust enhancement. Additionally, to fully facilitate the learning of cross-modal correspondence, we conduct large-scale multimodal pretraining based on the RGB-only dataset with synthetic auxiliary modalities. Extensive experiments demonstrate that AMNet could handle arbitrary inference-time modality combinations and exhibits superior performance for LLVE under modality absence conditions. Code and models are available on the project page.
Recent one-step generative models accelerate sampling by learning deterministic flow maps of the underlying dynamics. These methods rely on learning from ordinary differential equations, leaving open how to define an exact distillation procedure for stochastic dynamics. We introduce the Itô map, an any-step stochastic flow map that takes an intermediate state and Brownian path and predicts future states in a single pass. The Itô map formulation yields novel estimators for inference-time control by providing cheap, differentiable access to posterior samples. Empirically, Itô maps produce diverse, conditionally valid endpoint samples from fixed intermediate states and support strong steering performance on synthetic and image-generation benchmarks. These results establish any-step SDE integration as a useful primitive for posterior sampling and stochastic control.
Flow Matching models have demonstrated strong performance across a wide range of generative tasks. However, their reliance on ODE-based iterative sampling incurs substantial computational overhead in inference, which limits their applicability in real-time scenes. While distillation is a promising solution, existing approaches largely borrow from diffusion-based score matching, often failing to exploit the intrinsic geometric structure of flows and suffering from training instability, high variance, and degraded generation quality. In this paper, we propose Mean Flow Distillation (MFD), a novel distillation framework tailored for flow matching models. We theoretically demonstrate that MFD acts as a temporal low-pass filter, effectively suppressing the high-frequency optimization noise inherent in variational score distillation (VSD) while ensuring global trajectory consistency. We further prove the Mean Flow Matching Theorem, establishing that matching expected average velocities is sufficient for strict distribution alignment. Empirically, on challenging tasks of high-dimensional manifolds including 4D occupancy forecasting and text-to-image generation, MFD achieves state-of-the-art performance, enabling high-fidelity single-step generation.
Multimodal large language models can write code to produce complex programs as well as use programs to do 3D modeling, which opens up a new avenue for 3D generation powered by their priors, world knowledge and reasoning. Yet existing benchmarks rarely evaluate 3D modeling through code. Such modeling demands more than runnable code: from a text or visual specification, a model must generate a parametric 3D program that is geometrically precise, semantically aligned and assembly-consistent. We introduce P3D-Bench, a benchmark for parametric 3D generation. Unlike a 3D mesh, a parametric 3D program exposes explicit dimensions, construction operations and part relations, revealing whether a model recovers a design's structure, not just its appearance. Under a unified protocol, P3D-Bench covers three task families (Text-to-3D, Image-to-3D and Assembly-3D) and scores each output for executability, geometric fidelity, topology, text-grounded constraints, multiview semantic alignment and part-level structure. We evaluate frontier MLLMs and text-only LLMs on 400 text cases, 400 image cases and 203 annotated assemblies, with domain-specific models as reference points. Our extensive evaluation yields three findings. First, assemblies are the hardest setting, where models still fail to compose multiple parts into a coherent structure. Second, models can often recover the global shape and semantic identity of the target object, yet fail to reproduce the precise parametric geometry specified by the input. Third, part-level modeling remains weak on assemblies, where models recover neither the geometry of each part nor the right number of parts. These results position P3D-Bench as a benchmark for evaluating precise parametric geometry and part-level structure in parametric 3D generation.
Virtual try-on aims to fit an in-shop clothing image onto a specific human body. An optimal virtual try-on method should provide diverse and flexible dressing options, accurately reflecting the varied wearing styles encountered in real-life scenarios, tailored to individual preferences and fashion aspirations. However, current methods predominantly perform a direct replacement of the original clothing with the target clothing, following the same dressing pattern. This limited control over clothing adaptation may result in fixed and monotonous try-on outputs. To delve into More Fashion Possibilities with Fine-Grained Adaptations in Virtual Try-On, we propose a novel virtual try-on method, termed MOFA-VTON, which allows adjustment for clothing adaptations in try-on results through simple sketches by users. Specifically, we first design a mask construction strategy that transforms user-drawn curve sketches into a dual-region mask, replacing the traditional clothing-agnostic mask and providing fine-grained layout guidance for the subsequent generation process. Further, we propose layout adjustment blocks that utilize the cross-attention mechanism to independently learn layout correspondences for upper and lower regions of the human body, refining the spatial arrangement of the two regions. With these implementations, our method enables flexible and fine-grained adaptations of target clothing, overcoming the constraints of a fixed layout. Extensive experiments on VITON-HD and DressCode datasets demonstrate that our proposed MOFA-VTON outperforms previous state-of-the-art methods and provides more fashion possibilities for virtual try-on.
Most existing deep learning-based PET image denoising methods assume a fixed and known dose reduction factor (DRF) for low-dose PET images. However, these methods encounter significant performance degradation when the DRF varies beyond the assumed one in practical applications. To address the challenge posed by varied DRFs, several preliminary studies focus on the task of universal PET image denoising, aiming to train a universal model over low-dose data across DRFs. Nonetheless, these vanilla universal models often struggle with misaligned styles present in different DRF data, leading to the \textit{style elimination issue} with a significant over-smoothing effect. To deal with this issue, we innovatively introduce domain generalization to PET image denoising and propose a universal PET image denoising network (UniPET) to achieve high-quality PET image denoising across diverse DRFs. UniPET comprises two primary innovations: a style alignment network (SAN) and a region-aware learning strategy (RALS). Specifically, SAN utilizes style alignment techniques derived from domain generalization to align and recover styles across different DRFs, ensuring the model's generalizability across various DRFs while effectively preserving styles. Furthermore, to enhance style recovery, RALS distinguishes between flat and stylized regions, exclusively conducting adversarial learning on the latter, thereby more effectively guiding the model's focus towards learning stylized regions. It is demonstrated that our proposed UniPET can adaptively recover different DRF styles and achieve high-quality PET image denoising across DRFs. Comprehensive experiments show that UniPET exhibits comparable performance to individual DRF-specific models at specific DRFs and realizes state-of-the-art performance in universal PET image denoising quantitatively, perceptually, and clinically.
Clinicians diagnose brain tumors by synthesizing patient symptoms, medical history, and quantitative imaging data from modalities such as MRI and CT scans into a unified clinical judgement. However, most deep learning models rely on MRI/CT images alone, failing to replicate the clinicians multimodal reasoning. We explore a two-branch multimodal network combining raw MRI scans with 91 extracted radiomic features (intensity, texture, shape, and boundary descriptors) to classify brain tumors into glioma, meningioma, pituitary, and no-tumor. A pre-trained CNN backbone encodes the image stream, whereas a dedicated MLP encodes the radiomic stream. Both streams are fused via concatenation, gated, or bidirectional cross-modal attention strategies. Across nine experimental runs on a balanced 7,200 image dataset, all multimodal configurations outperform unimodal baselines with gated fusion achieving the best accuracy of 96.13%.
A global shortage of trained sonographers limits prenatal ultrasound screening in low- and middle-income countries, where over half of pregnant women receive no skilled sonography. Current deep learning approaches address detection, segmentation, or classification in isolation, each demanding a separate model and expert-specified labels at inference. We present FADA, a unified vision-language model built on Qwen3.5-VL that performs clinical interpretation, classification, detection, and segmentation through a single interpretation-first pipeline without external labels. FADA distills knowledge from four domain-specific foundation models (FetalCLIP, UltraSAM, USF-MAE, UltraFedFM) via offline pre-computed feature caching. Selective distillation, which applies feature alignment only to annotation tasks while interpretation relies on standard fine-tuning, consistently outperforms full distillation across most evaluation axes. The recommended variant, FADA-SKD, achieves 0.8820 mean Dice for segmentation, 0.7671 mAP@0.50 for detection, and 100% structured interpretation compliance. Expert sonographer validation across 237 images confirms clinically acceptable outputs in both autonomous and human-in-the-loop modes, with 73.5% of interpretations scoring perfectly under clinician guidance. The system is trainable on a single consumer GPU and deployable without cloud connectivity. We validate edge deployment by running the compressed 0.8B model on a commodity smartphone (Qualcomm Snapdragon 7 Gen 1, 12 GB RAM) using llama.cpp with GGUF quantization, completing the full 5-phase pipeline in approximately 60 seconds entirely offline. This establishes a practical pathway for integrating AI-assisted fetal assessment with portable ultrasound devices, directly addressing diagnostic access gaps in resource-constrained settings. Code, models, and data are available at https://github.com/mahmoodphd/FADA.