Image-to-image translation is the process of converting an image from one domain to another using deep learning techniques.
Professional designers work from client briefs that specify goals and constraints but often lack concrete design details. Translating these abstract requirements into visual designs poses a central challenge, yet existing tools address specific aspects or induce fixation through complete outputs. Through interviews with six professional designers, we identified how designers address this challenge: first structuring ambiguous requirements, then exploring individual elements, and finally recombining alternatives. We developed Brief2Design, supporting this workflow through requirement extraction and recommendation, element-level exploration for objects, backgrounds, text, typography, and composition, and flexible recombination of selected elements. A within-subjects study with twelve designers compared Brief2Design against a conversational baseline. The structured approach increased prompt diversity and received high ratings for requirement extraction and recommendation, but required longer generation time and achieved comparable image diversity. These findings reveal that structured workflows benefit requirement clarification at the cost of efficiency, informing design trade-offs for AI-assisted graphic design tools.
Image generative models have become indispensable tools to yield exquisite high-resolution (HR) images for everyone, ranging from general users to professional designers. However, a desired outcome often requires generating a large number of HR images with different prompts and seeds, resulting in high computational cost for both users and service providers. Generating low-resolution (LR) images first could alleviate computational burden, but it is not straightforward how to generate LR images that are perceptually consistent with their HR counterparts. Here, we consider the task of generating high-fidelity LR images, called Previews, that preserve perceptual similarity of their HR counterparts for an efficient workflow, allowing users to identify promising candidates before generating the final HR image. We propose the commutator-zero condition to ensure the LR-HR perceptual consistency for flow matching models, leading to the proposed training-free solution with downsampling matrix selection and commutator-zero guidance. Extensive experiments show that our method can generate LR images with up to 33\% computation reduction while maintaining HR perceptual consistency. When combined with existing acceleration techniques, our method achieves up to 3$\times$ speedup. Moreover, our formulation can be extended to image manipulations, such as warping and translation, demonstrating its generalizability.
Multimodal imaging analysis often relies on joint latent representations, yet these approaches rarely define what information is shared versus modality-specific. Clarifying this distinction is clinically relevant, as it delineates the irreducible contribution of each modality and informs rational acquisition strategies. We propose a subspace decomposition framework that reframes multimodal fusion as a problem of orthogonal subspace separation rather than translation. We decompose Prostate-Specific Membrane Antigen (PSMA) PET uptake into an MRI-explainable physiological envelope and an orthogonal residual reflecting signal components not expressible within the MRI feature manifold. Using multiparametric MRI, we train an intensity-based, non-spatial implicit neural representation (INR) to map MRI feature vectors to PET uptake. We introduce a projection-based regularization using singular value decomposition to penalize residual components lying within the span of the MRI feature manifold. This enforces mathematical orthogonality between tissue-level physiological properties (structure, diffusion, perfusion) and intracellular PSMA expression. Tested on 13 prostate cancer patients, the model demonstrates that residual components spanned by MRI features are absorbed into the learned envelope, while the orthogonal residual is largest in tumour regions. This indicates that PSMA PET contains signal components not recoverable from MRI-derived physiological descriptors. The resulting decomposition provides a structured characterization of modality complementarity grounded in representation geometry rather than image translation.
Photon-counting CT (PCCT) provides superior image quality with higher spatial resolution and lower noise compared to conventional energy-integrating CT (EICT), but its limited clinical availability restricts large-scale research and clinical deployment. To bridge this gap, we propose SUMI, a simulated degradation-to-enhancement method that learns to reverse realistic acquisition artifacts in low-quality EICT by leveraging high-quality PCCT as reference. Our central insight is to explicitly model realistic acquisition degradations, transforming PCCT into clinically plausible lower-quality counterparts and learning to invert this process. The simulated degradations were validated for clinical realism by board-certified radiologists, enabling faithful supervision without requiring paired acquisitions at scale. As outcomes of this technical contribution, we: (1) train a latent diffusion model on 1,046 PCCTs, using an autoencoder first pre-trained on both these PCCTs and 405,379 EICTs from 145 hospitals to extract general CT latent features that we release for reuse in other generative medical imaging tasks; (2) construct a large-scale dataset of over 17,316 publicly available EICTs enhanced to PCCT-like quality, with radiologist-validated voxel-wise annotations of airway trees, arteries, veins, lungs, and lobes; and (3) demonstrate substantial improvements: across external data, SUMI outperforms state-of-the-art image translation methods by 15% in SSIM and 20% in PSNR, improves radiologist-rated clinical utility in reader studies, and enhances downstream top-ranking lesion detection performance, increasing sensitivity by up to 15% and F1 score by up to 10%. Our results suggest that emerging imaging advances can be systematically distilled into routine EICT using limited high-quality scans as reference.
Activation steering is a popular white-box control technique that modifies model activations to elicit an abstract change in output behavior. It has also become a standard tool in interpretability (e.g., probing truthfulness, or translating activations into human-readable explanations and safety research (e.g., studying jailbreakability). However, it is unclear whether steered activation states are realizable by any textual prompt. In this work, we cast this question as a surjectivity problem: for a fixed model, does every steered activation admit a pre-image under the model's natural forward pass? Under practical assumptions, we prove that activation steering pushes the residual stream off the manifold of states reachable from discrete prompts. Almost surely, no prompt can reproduce the same internal behavior induced by steering. We also illustrate this finding empirically across three widely used LLMs. Our results establish a formal separation between white-box steerability and black-box prompting. We therefore caution against interpreting the ease and success of activation steering as evidence of prompt-based interpretability or vulnerability, and argue for evaluation protocols that explicitly decouple white-box and black-box interventions.
Scanning Electron Microscopy (SEM) is indispensable in modern materials science, enabling high-resolution imaging across a wide range of structural, chemical, and functional investigations. However, SEM imaging remains constrained by task-specific models and labor-intensive acquisition processes that limit its scalability across diverse applications. Here, we introduce the first foundation model for SEM images, pretrained on a large corpus of multi-instrument, multi-condition scientific micrographs, enabling generalization across diverse material systems and imaging conditions. Leveraging a self-supervised transformer architecture, our model learns rich and transferable representations that can be fine-tuned or adapted to a wide range of downstream tasks. As a compelling demonstration, we focus on defocus-to-focus image translation-an essential yet underexplored challenge in automated microscopy pipelines. Our method not only restores focused detail from defocused inputs without paired supervision but also outperforms state-of-the-art techniques across multiple evaluation metrics. This work lays the groundwork for a new class of adaptable SEM models, accelerating materials discovery by bridging foundational representation learning with real-world imaging needs.
AfriVoices-KE is a large-scale multilingual speech dataset comprising approximately 3,000 hours of audio across five Kenyan languages: Dholuo, Kikuyu, Kalenjin, Maasai, and Somali. The dataset includes 750 hours of scripted speech and 2,250 hours of spontaneous speech, collected from 4,777 native speakers across diverse regions and demographics. This work addresses the critical underrepresentation of African languages in speech technology by providing a high-quality, linguistically diverse resource. Data collection followed a dual methodology: scripted recordings drew from compiled text corpora, translations, and domain-specific generated sentences spanning eleven domains relevant to the Kenyan context, while unscripted speech was elicited through textual and image prompts to capture natural linguistic variation and dialectal nuances. A customized mobile application enabled contributors to record using smartphones. Quality assurance operated at multiple layers, encompassing automated signal-to-noise ratio validation prior to recording and human review for content accuracy. Though the project encountered challenges common to low-resource settings, including unreliable infrastructure, device compatibility issues, and community trust barriers, these were mitigated through local mobilizers, stakeholder partnerships, and adaptive training protocols. AfriVoices-KE provides a foundational resource for developing inclusive automatic speech recognition and text-to-speech systems, while advancing the digital preservation of Kenya's linguistic heritage.
Diffusion models have achieved remarkable progress in video generation, but their controllability remains a major limitation. Key scene factors such as layout, lighting, and camera trajectory are often entangled or only weakly modeled, restricting their applicability in domains like filmmaking and virtual production where explicit scene control is essential. We present LiVER, a diffusion-based framework for scene-controllable video generation. To achieve this, we introduce a novel framework that conditions video synthesis on explicit 3D scene properties, supported by a new large-scale dataset with dense annotations of object layout, lighting, and camera parameters. Our method disentangles these properties by rendering control signals from a unified 3D representation. We propose a lightweight conditioning module and a progressive training strategy to integrate these signals into a foundational video diffusion model, ensuring stable convergence and high fidelity. Our framework enables a wide range of applications, including image-to-video and video-to-video synthesis where the underlying 3D scene is fully editable. To further enhance usability, we develop a scene agent that automatically translates high-level user instructions into the required 3D control signals. Experiments show that LiVER achieves state-of-the-art photorealism and temporal consistency while enabling precise, disentangled control over scene factors, setting a new standard for controllable video generation.
Tabular data, widely used in various applications such as industrial control systems, finance, and supply chain, often contains complex interrelationships among its attributes. Data disentanglement seeks to transform such data into latent variables with reduced interdependencies, facilitating more effective and efficient processing. Despite the extensive studies on data disentanglement over image, text, or audio data, tabular data disentanglement may require further investigation due to the more intricate attribute interactions typically found in tabular data. Moreover, due to the highly complex interrelationships, direct translation from other data domains results in suboptimal data disentanglement. Existing tabular data disentanglement methods, such as factor analysis, CT-GAN, and VAE face limitations including scalability issues, mode collapse, and poor extrapolation. In this paper, we propose the use of a framework to provide a systematic view on tabular data disentanglement that modularizes the process into four core components: data extraction, data modeling, model analysis, and latent representation extrapolation. We believe this work provides a deeper understanding of tabular data disentanglement and existing methods, and lays the foundation for potential future research in developing robust, efficient, and scalable data disentanglement techniques. Finally, we demonstrate the framework's applicability through a case study on synthetic tabular data generation, showcasing its potential in the particular downstream task of data synthesis.
Magnetic Resonance Imaging (MRI) is a cornerstone in medicine and healthcare but suffers from long acquisition times. Traditional accelerated MRI methods optimize for generic image quality, lacking adaptability for specific clinical tasks. To address this, we introduce PASS (Personalized, Anomaly-aware Sampling and reconStruction), an intelligent MRI framework that leverages a Vision-Language Model (VLM) to guide a deep unrolling network for task-oriented, fast imaging. PASS dynamically personalizes the imaging pipeline through three core contributions: (1) a deep unrolled reconstruction network derived from a physics-based MRI model; (2) a sampling module that generates patient-specific $k$-space trajectories; and (3) an anomaly-aware prior, extracted from a pretrained VLM, which steers both sampling and reconstruction toward clinically relevant regions. By integrating the high-level clinical reasoning of a VLM with an interpretable, physics-aware network, PASS achieves superior image quality across diverse anatomies, contrasts, anomalies, and acceleration factors. This enhancement directly translates to improvements in downstream diagnostic tasks, including fine-grained anomaly detection, localization, and diagnosis.