Image-to-image translation is the process of converting an image from one domain to another using deep learning techniques.
Domain gaps arising from variations in imaging devices and population distributions pose significant challenges for machine learning in medical image analysis. Existing image-to-image translation methods primarily aim to learn mappings between domains, often generating diverse synthetic data with variations in anatomical scale and shape, but they usually overlook spatial correspondence during the translation process. For clinical applications, traceability, defined as the ability to provide pixel-level correspondences between original and translated images, is equally important. This property enhances clinical interpretability but has been largely overlooked in previous approaches. To address this gap, we propose Plasticine, which is, to the best of our knowledge, the first end-to-end image-to-image translation framework explicitly designed with traceability as a core objective. Our method combines intensity translation and spatial transformation within a denoising diffusion framework. This design enables the generation of synthetic images with interpretable intensity transitions and spatially coherent deformations, supporting pixel-wise traceability throughout the translation process.
Handwritten text recognition (HTR) and machine translation continue to pose significant challenges, particularly for low-resource languages like Marathi, which lack large digitized corpora and exhibit high variability in handwriting styles. The conventional approach to address this involves a two-stage pipeline: an OCR system extracts text from handwritten images, which is then translated into the target language using a machine translation model. In this work, we explore and compare the performance of traditional OCR-MT pipelines with Vision Large Language Models that aim to unify these stages and directly translate handwritten text images in a single, end-to-end step. Our motivation is grounded in the urgent need for scalable, accurate translation systems to digitize legal records such as FIRs, charge sheets, and witness statements in India's district and high courts. We evaluate both approaches on a curated dataset of handwritten Marathi legal documents, with the goal of enabling efficient legal document processing, even in low-resource environments. Our findings offer actionable insights toward building robust, edge-deployable solutions that enhance access to legal information for non-native speakers and legal professionals alike.
Purpose: To provide a diverse, high-quality dataset of color fundus images (CFIs) with detailed artery-vein (A/V) segmentation annotations, supporting the development and evaluation of machine learning algorithms for vascular analysis in ophthalmology. Methods: CFIs were sampled from the longitudinal Rotterdam Study (RS), encompassing a wide range of ages, devices, and capture conditions. Images were annotated using a custom interface that allowed graders to label arteries, veins, and unknown vessels on separate layers, starting from an initial vessel segmentation mask. Connectivity was explicitly verified and corrected using connected component visualization tools. Results: The dataset includes 1024x1024-pixel PNG images in three modalities: original RGB fundus images, contrast-enhanced versions, and RGB-encoded A/V masks. Image quality varied widely, including challenging samples typically excluded by automated quality assessment systems, but judged to contain valuable vascular information. Conclusion: This dataset offers a rich and heterogeneous source of CFIs with high-quality segmentations. It supports robust benchmarking and training of machine learning models under real-world variability in image quality and acquisition settings. Translational Relevance: By including connectivity-validated A/V masks and diverse image conditions, this dataset enables the development of clinically applicable, generalizable machine learning tools for retinal vascular analysis, potentially improving automated screening and diagnosis of systemic and ocular diseases.
The creation of high-fidelity, physically-based rendering (PBR) materials remains a bottleneck in many graphics pipelines, typically requiring specialized equipment and expert-driven post-processing. To democratize this process, we present MatE, a novel method for generating tileable PBR materials from a single image taken under unconstrained, real-world conditions. Given an image and a user-provided mask, MatE first performs coarse rectification using an estimated depth map as a geometric prior, and then employs a dual-branch diffusion model. Leveraging a learned consistency from rotation-aligned and scale-aligned training data, this model further rectify residual distortions from the coarse result and translate it into a complete set of material maps, including albedo, normal, roughness and height. Our framework achieves invariance to the unknown illumination and perspective of the input image, allowing for the recovery of intrinsic material properties from casual captures. Through comprehensive experiments on both synthetic and real-world data, we demonstrate the efficacy and robustness of our approach, enabling users to create realistic materials from real-world image.
User interface to code (UI2Code) aims to generate executable code that can faithfully reconstruct a given input UI. Prior work focuses largely on web pages and mobile screens, leaving app widgets underexplored. Unlike web or mobile UIs with rich hierarchical context, widgets are compact, context-free micro-interfaces that summarize key information through dense layouts and iconography under strict spatial constraints. Moreover, while (image, code) pairs are widely available for web or mobile UIs, widget designs are proprietary and lack accessible markup. We formalize this setting as the Widget-to-Code (Widget2Code) and introduce an image-only widget benchmark with fine-grained, multi-dimensional evaluation metrics. Benchmarking shows that although generalized multimodal large language models (MLLMs) outperform specialized UI2Code methods, they still produce unreliable and visually inconsistent code. To address these limitations, we develop a baseline that jointly advances perceptual understanding and structured code generation. At the perceptual level, we follow widget design principles to assemble atomic components into complete layouts, equipped with icon retrieval and reusable visualization modules. At the system level, we design an end-to-end infrastructure, WidgetFactory, which includes a framework-agnostic widget-tailored domain-specific language (WidgetDSL) and a compiler that translates it into multiple front-end implementations (e.g., React, HTML/CSS). An adaptive rendering module further refines spatial dimensions to satisfy compactness constraints. Together, these contributions substantially enhance visual fidelity, establishing a strong baseline and unified infrastructure for future Widget2Code research.
Fluorescence lifetime imaging microscopy (FLIM) is a powerful quantitative technique that provides metabolic and molecular contrast, offering strong translational potential for label-free, real-time diagnostics. However, its clinical adoption remains limited by long pixel dwell times and low signal-to-noise ratio (SNR), which impose a stricter resolution-speed trade-off than conventional optical imaging approaches. Here, we introduce FLIM_PSR_k, a deep learning-based multi-channel pixel super-resolution (PSR) framework that reconstructs high-resolution FLIM images from data acquired with up to a 5-fold increased pixel size. The model is trained using the conditional generative adversarial network (cGAN) framework, which, compared to diffusion model-based alternatives, delivers a more robust PSR reconstruction with substantially shorter inference times, a crucial advantage for practical deployment. FLIM_PSR_k not only enables faster image acquisition but can also alleviate SNR limitations in autofluorescence-based FLIM. Blind testing on held-out patient-derived tumor tissue samples demonstrates that FLIM_PSR_k reliably achieves a super-resolution factor of k = 5, resulting in a 25-fold increase in the space-bandwidth product of the output images and revealing fine architectural features lost in lower-resolution inputs, with statistically significant improvements across various image quality metrics. By increasing FLIM's effective spatial resolution, FLIM_PSR_k advances lifetime imaging toward faster, higher-resolution, and hardware-flexible implementations compatible with low-numerical-aperture and miniaturized platforms, better positioning FLIM for translational applications.
Neural rendering for interactive applications requires translating geometric and material properties (G-buffer) to photorealistic images with realistic lighting on a frame-by-frame basis. While recent diffusion-based approaches show promise for G-buffer-conditioned image synthesis, they face critical limitations: single-image models like RGBX generate frames independently without temporal consistency, while video models like DiffusionRenderer are too computationally expensive for most consumer gaming sets ups and require complete sequences upfront, making them unsuitable for interactive applications where future frames depend on user input. We introduce FrameDiffuser, an autoregressive neural rendering framework that generates temporally consistent, photorealistic frames by conditioning on G-buffer data and the models own previous output. After an initial frame, FrameDiffuser operates purely on incoming G-buffer data, comprising geometry, materials, and surface properties, while using its previously generated frame for temporal guidance, maintaining stable, temporal consistent generation over hundreds to thousands of frames. Our dual-conditioning architecture combines ControlNet for structural guidance with ControlLoRA for temporal coherence. A three-stage training strategy enables stable autoregressive generation. We specialize our model to individual environments, prioritizing consistency and inference speed over broad generalization, demonstrating that environment-specific training achieves superior photorealistic quality with accurate lighting, shadows, and reflections compared to generalized approaches.
Effective aneurysm detection is essential to avert life-threatening hemorrhages, but it remains challenging due to the subtle morphology of the aneurysm, pronounced class imbalance, and the scarcity of annotated data. We introduce SAMM2D, a dual-encoder framework that achieves an AUC of 0.686 on the RSNA intracranial aneurysm dataset; an improvement of 32% over the clinical baseline. In a comprehensive ablation across six augmentation regimes, we made a striking discovery: any form of data augmentation degraded performance when coupled with a strong pretrained backbone. Our unaugmented baseline model outperformed all augmented variants by 1.75--2.23 percentage points (p < 0.01), overturning the assumption that "more augmentation is always better" in low-data medical settings. We hypothesize that ImageNet-pretrained features already capture robust invariances, rendering additional augmentations both redundant and disruptive to the learned feature manifold. By calibrating the decision threshold, SAMM2D reaches 95% sensitivity, surpassing average radiologist performance, and translates to a projected \$13.9M in savings per 1,000 patients in screening applications. Grad-CAM visualizations confirm that 85% of true positives attend to relevant vascular regions (62% IoU with expert annotations), demonstrating the model's clinically meaningful focus. Our results suggest that future medical imaging workflows could benefit more from strong pretraining than from increasingly complex augmentation pipelines.
Data scarcity and distribution shift pose major challenges for masked face detection and recognition. We propose a two-step generative data augmentation framework that combines rule-based mask warping with unpaired image-to-image translation using GANs, enabling the generation of realistic masked-face samples beyond purely synthetic transformations. Compared to rule-based warping alone, the proposed approach yields consistent qualitative improvements and complements existing GAN-based masked face generation methods such as IAMGAN. We introduce a non-mask preservation loss and stochastic noise injection to stabilize training and enhance sample diversity. Experimental observations highlight the effectiveness of the proposed components and suggest directions for future improvements in data-centric augmentation for face recognition tasks.
We introduce a finance & accounting benchmark (Finch) for evaluating AI agents on real-world, enterprise-grade professional workflows -- interleaving data entry, structuring, formatting, web search, cross-file retrieval, calculation, modeling, validation, translation, visualization, and reporting. Finch is sourced from authentic enterprise workspaces at Enron (15,000 spreadsheets and 500,000 emails from 150 employees) and other financial institutions, preserving in-the-wild messiness across multimodal artifacts (text, tables, formulas, charts, code, and images) and spanning diverse domains such as budgeting, trading, and asset management. We propose a workflow construction process that combines LLM-assisted discovery with expert annotation: (1) LLM-assisted, expert-verified derivation of workflows from real-world email threads and version histories of spreadsheet files, and (2) meticulous expert annotation for workflows, requiring over 700 hours of domain-expert effort. This yields 172 composite workflows with 384 tasks, involving 1,710 spreadsheets with 27 million cells, along with PDFs and other artifacts, capturing the intrinsically messy, long-horizon, knowledge-intensive, and collaborative nature of real-world enterprise work. We conduct both human and automated evaluations of frontier AI systems including GPT 5.1, Claude Sonnet 4.5, Gemini 3 Pro, Grok 4, and Qwen 3 Max, and GPT 5.1 Pro spends 48 hours in total yet passes only 38.4% of workflows, while Claude Sonnet 4.5 passes just 25.0%. Comprehensive case studies further surface the challenges that real-world enterprise workflows pose for AI agents.