MedGemma 1.5 Technical Report

We introduce MedGemma 1.5 4B, the latest model in the MedGemma collection. MedGemma 1.5 expands on MedGemma 1 by integrating additional capabilities: high-dimensional medical imaging (CT/MRI volumes and histopathology whole slide images), anatomical localization via bounding boxes, multi-timepoint chest X-ray analysis, and improved medical document understanding (lab reports, electronic health records). We detail the innovations required to enable these modalities within a single architecture, including new training data, long-context 3D volume slicing, and whole-slide pathology sampling. Compared to MedGemma 1 4B, MedGemma 1.5 4B demonstrates significant gains in these new areas, improving 3D MRI condition classification accuracy by 11% and 3D CT condition classification by 3% (absolute improvements). In whole slide pathology imaging, MedGemma 1.5 4B achieves a 47% macro F1 gain. Additionally, it improves anatomical localization with a 35% increase in Intersection over Union on chest X-rays and achieves a 4% macro accuracy for longitudinal (multi-timepoint) chest x-ray analysis. Beyond its improved multimodal performance over MedGemma 1, MedGemma 1.5 improves on text-based clinical knowledge and reasoning, improving by 5% on MedQA accuracy and 22% on EHRQA accuracy. It also achieves an average of 18% macro F1 on 4 different lab report information extraction datasets (EHR Datasets 2, 3, 4, and Mendeley Clinical Laboratory Test Reports). Taken together, MedGemma 1.5 serves as a robust, open resource for the community, designed as an improved foundation on which developers can create the next generation of medical AI systems. Resources and tutorials for building upon MedGemma 1.5 can be found at https://goo.gle/MedGemma.

Toward Unified Fine-Grained Vehicle Classification and Automatic License Plate Recognition

Extracting vehicle information from surveillance images is essential for intelligent transportation systems, enabling applications such as traffic monitoring and criminal investigations. While Automatic License Plate Recognition (ALPR) is widely used, Fine-Grained Vehicle Classification (FGVC) offers a complementary approach by identifying vehicles based on attributes such as color, make, model, and type. Although there have been advances in this field, existing studies often assume well-controlled conditions, explore limited attributes, and overlook FGVC integration with ALPR. To address these gaps, we introduce UFPR-VeSV, a dataset comprising 24,945 images of 16,297 unique vehicles with annotations for 13 colors, 26 makes, 136 models, and 14 types. Collected from the Military Police of Paraná (Brazil) surveillance system, the dataset captures diverse real-world conditions, including partial occlusions, nighttime infrared imaging, and varying lighting. All FGVC annotations were validated using license plate information, with text and corner annotations also being provided. A qualitative and quantitative comparison with established datasets confirmed the challenging nature of our dataset. A benchmark using five deep learning models further validated this, revealing specific challenges such as handling multicolored vehicles, infrared images, and distinguishing between vehicle models that share a common platform. Additionally, we apply two optical character recognition models to license plate recognition and explore the joint use of FGVC and ALPR. The results highlight the potential of integrating these complementary tasks for real-world applications. The UFPR-VeSV dataset is publicly available at: https://github.com/Lima001/UFPR-VeSV-Dataset.

A Generative Foundation Model for Multimodal Histopathology

Accurate diagnosis and treatment of complex diseases require integrating histological, molecular, and clinical data, yet in practice these modalities are often incomplete owing to tissue scarcity, assay cost, and workflow constraints. Existing computational approaches attempt to impute missing modalities from available data but rely on task-specific models trained on narrow, single source-target pairs, limiting their generalizability. Here we introduce MuPD (Multimodal Pathology Diffusion), a generative foundation model that embeds hematoxylin and eosin (H&E)-stained histology, molecular RNA profiles, and clinical text into a shared latent space through a diffusion transformer with decoupled cross-modal attention. Pretrained on 100 million histology image patches, 1.6 million text-histology pairs, and 10.8 million RNA-histology pairs spanning 34 human organs, MuPD supports diverse cross-modal synthesis tasks with minimal or no task-specific fine-tuning. For text-conditioned and image-to-image generation, MuPD synthesizes histologically faithful tissue architectures, reducing Fréchet inception distance (FID) scores by 50% relative to domain-specific models and improving few-shot classification accuracy by up to 47% through synthetic data augmentation. For RNA-conditioned histology generation, MuPD reduces FID by 23% compared with the next-best method while preserving cell-type distributions across five cancer types. As a virtual stainer, MuPD translates H&E images to immunohistochemistry and multiplex immunofluorescence, improving average marker correlation by 37% over existing approaches. These results demonstrate that a single, unified generative model pretrained across heterogeneous pathology modalities can substantially outperform specialized alternatives, providing a scalable computational framework for multimodal histopathology.

Beyond Standard Benchmarks: A Systematic Audit of Vision-Language Model's Robustness to Natural Semantic Variation Across Diverse Tasks

Recent advances in vision-language models (VLMs) trained on web-scale image-text pairs have enabled impressive zero-shot transfer across a diverse range of visual tasks. However, comprehensive and independent evaluation beyond standard benchmarks is essential to understand their robustness, limitations, and real-world applicability. This paper presents a systematic evaluation framework for VLMs under natural adversarial scenarios for diverse downstream tasks, which has been overlooked in previous evaluation works. We evaluate a wide range of VLMs (CLIP, robust CLIP, BLIP2, and SigLIP2) on curated adversarial datasets (typographic attacks, ImageNet-A, and natural language-induced adversarial examples). We measure the natural adversarial performance of selected VLMs for zero-shot image classification, semantic segmentation, and visual question answering. Our analysis reveals that robust CLIP models can amplify natural adversarial vulnerabilities, and CLIP models significantly reduce performance for natural language-induced adversarial examples. Additionally, we provide interpretable analyses to identify failure modes. We hope our findings inspire future research in robust and fair multimodal pattern recognition.

Enhancing Hyperspace Analogue to Language (HAL) Representations via Attention-Based Pooling for Text Classification

The Hyperspace Analogue to Language (HAL) model relies on global word co-occurrence matrices to construct distributional semantic representations. While these representations capture lexical relationships effectively, aggregating them into sentence-level embeddings via standard mean pooling often results in information loss. Mean pooling assigns equal weight to all tokens, thereby diluting the impact of contextually salient words with uninformative structural tokens. In this paper, we address this limitation by integrating a learnable, temperature-scaled additive attention mechanism into the HAL representation pipeline. To mitigate the sparsity and high dimensionality of the raw co-occurrence matrices, we apply Truncated Singular Value Decomposition (SVD) to project the vectors into a dense latent space prior to the attention layer. We evaluate the proposed architecture on the IMDB sentiment analysis dataset. Empirical results demonstrate that the attention-based pooling approach achieves a test accuracy of 82.38%, yielding an absolute improvement of 6.74 percentage points over the traditional mean pooling baseline (75.64%). Furthermore, qualitative analysis of the attention weights indicates that the mechanism successfully suppresses stop-words and selectively attends to sentiment-bearing tokens, improving both classification performance and model interpretability.

ContextClaim: A Context-Driven Paradigm for Verifiable Claim Detection

Verifiable claim detection asks whether a claim expresses a factual statement that can, in principle, be assessed against external evidence. As an early filtering stage in automated fact-checking, it plays an important role in reducing the burden on downstream verification components. However, existing approaches to claim detection, whether based on check-worthiness or verifiability, rely solely on the claim text itself. This is a notable limitation for verifiable claim detection in particular, where determining whether a claim is checkable may benefit from knowing what entities and events it refers to and whether relevant information exists to support verification. Inspired by the established role of evidence retrieval in later-stage claim verification, we propose Context-Driven Claim Detection (ContextClaim), a paradigm that advances retrieval to the detection stage. ContextClaim extracts entity mentions from the input claim, retrieves relevant information from Wikipedia as a structured knowledge source, and employs large language models to produce concise contextual summaries for downstream classification. We evaluate ContextClaim on two datasets covering different topics and text genres, the CheckThat! 2022 COVID-19 Twitter dataset and the PoliClaim political debate dataset, across encoder-only and decoder-only models under fine-tuning, zero-shot, and few-shot settings. Results show that context augmentation can improve verifiable claim detection, although its effectiveness varies across domains, model architectures, and learning settings. Through component analysis, human evaluation, and error analysis, we further examine when and why the retrieved context contributes to more reliable verifiability judgments.

Beyond Via: Analysis and Estimation of the Impact of Large Language Models in Academic Papers

Through an analysis of arXiv papers, we report several shifts in word usage that are likely driven by large language models (LLMs) but have not previously received sufficient attention, such as the increased frequency of "beyond" and "via" in titles and the decreased frequency of "the" and "of" in abstracts. Due to the similarities among different LLMs, experiments show that current classifiers struggle to accurately determine which specific model generated a given text in multi-class classification tasks. Meanwhile, variations across LLMs also result in evolving patterns of word usage in academic papers. By adopting a direct and highly interpretable linear approach and accounting for differences between models and prompts, we quantitatively assess these effects and show that real-world LLM usage is heterogeneous and dynamic.

LGSE: Lexically Grounded Subword Embedding Initialization for Low-Resource Language Adaptation

Adapting pretrained language models to low-resource, morphologically rich languages remains a significant challenge. Existing vocabulary expansion methods typically rely on arbitrarily segmented subword units, resulting in fragmented lexical representations and loss of critical morphological information. To address this limitation, we propose the Lexically Grounded Subword Embedding Initialization (LGSE) framework, which introduces morphologically informed segmentation for initializing embeddings of novel tokens. Instead of using random vectors or arbitrary subwords, LGSE decomposes words into their constituent morphemes and constructs semantically coherent embeddings by averaging pretrained subword or FastText-based morpheme representations. When a token cannot be segmented into meaningful morphemes, its embedding is constructed using character n-gram representations to capture structural information. During Language-Adaptive Pretraining, we apply a regularization term that penalizes large deviations of newly introduced embeddings from their initialized values, preserving alignment with the original pretrained embedding space while enabling adaptation to the target language. To isolate the effect of initialization, we retain the original pre-trained model vocabulary and tokenizer and update only the new embeddings during adaptation. We evaluate LGSE on three NLP tasks: Question Answering, Named Entity Recognition, and Text Classification, in two morphologically rich, low-resource languages: Amharic and Tigrinya, where morphological segmentation resources are available. Experimental results show that LGSE consistently outperforms baseline methods across all tasks, demonstrating the effectiveness of morphologically grounded embedding initialization for improving representation quality in underrepresented languages. Project resources are available in the GitHub link.

ARGENT: Adaptive Hierarchical Image-Text Representations

Large-scale Vision-Language Models (VLMs) such as CLIP learn powerful semantic representations but operate in Euclidean space, which fails to capture the inherent hierarchical structure of visual and linguistic concepts. Hyperbolic geometry, with its exponential volume growth, offers a principled alternative for embedding such hierarchies with low distortion. However, existing hyperbolic VLMs use entailment losses that are unstable: as parent embeddings contract toward the origin, their entailment cones widen toward a half-space, causing catastrophic cone collapse that destroys the intended hierarchy. Additionally, hierarchical evaluation of these models remains unreliable, being largely retrieval-based and correlation-based metrics and prone to taxonomy dependence and ambiguous negatives. To address these limitations, we propose an adaptive entailment loss paired with a norm regularizer that prevents cone collapse without heuristic aperture clipping. We further introduce an angle-based probabilistic entailment protocol (PEP) for evaluating hierarchical understanding, scored with AUC-ROC and Average Precision. This paper introduces a stronger hyperbolic VLM baseline ARGENT, Adaptive hieRarchical imaGe-tExt represeNTation. ARGENT improves the SOTA hyperbolic VLM by 0.7, 1.1, and 0.8 absolute points on image classification, text-to-image retrieval, and proposed hierarchical metrics, respectively.

Unlocking Few-Shot Capabilities in LVLMs via Prompt Conditioning and Head Selection

Current Large Vision Language Models (LVLMs) excel at many zero-shot tasks like image captioning, visual question answering and OCR. However, these same models suffer from poor performance at image classification tasks, underperforming against CLIP-based methods. Notably, this gap is surprising because many LVLMs use CLIP-pretrained vision encoders. Yet LVLMs are not inherently limited by CLIP's architecture with independent vision and text encoders. In CLIP, this separation biases classification toward class-name matching rather than joint visual-text reasoning. In this paper we show that, despite their poor raw performance, LVLMs can improve visual feature class separability at inference using prompt conditioning, and LVLMs' internal representations, especially attention heads, can outperform the model itself at zero-shot and few-shot classification. We introduce Head Ensemble Classifiers (HEC) to bridge the performance gap between CLIP-based and LVLM-based classification methods. Inspired by Gaussian Discriminant Analysis, HEC ranks the most discriminative vision and text heads and combines them into a training-free classifier. We show that HEC achieves state-of-the-art performance in few-shot and zero-shot classification across 12 datasets.