Motivation: Cryo-Electron Tomography (cryo-ET) is a 3D bioimaging tool that visualizes the structural and spatial organization of macromolecules at a near-native state in single cells, which has broad applications in life science. However, the systematic structural recognition and recovery of macromolecules captured by cryo-ET are difficult due to high structural complexity and imaging limits. Deep learning based subtomogram classification have played critical roles for such tasks. As supervised approaches, however, their performance relies on sufficient and laborious annotation on a large training dataset. Results: To alleviate this major labeling burden, we proposed a Hybrid Active Learning (HAL) framework for querying subtomograms for labelling from a large unlabeled subtomogram pool. Firstly, HAL adopts uncertainty sampling to select the subtomograms that have the most uncertain predictions. Moreover, to mitigate the sampling bias caused by such strategy, a discriminator is introduced to judge if a certain subtomogram is labeled or unlabeled and subsequently the model queries the subtomogram that have higher probabilities to be unlabeled. Additionally, HAL introduces a subset sampling strategy to improve the diversity of the query set, so that the information overlap is decreased between the queried batches and the algorithmic efficiency is improved. Our experiments on subtomogram classification tasks using both simulated and real data demonstrate that we can achieve comparable testing performance (on average only 3% accuracy drop) by using less than 30% of the labeled subtomograms, which shows a very promising result for subtomogram classification task with limited labeling resources.
In adversarial training (AT), the main focus has been the objective and optimizer while the model has been less studied, so that the models being used are still those classic ones in standard training (ST). Classic network architectures (NAs) are generally worse than searched NAs in ST, which should be the same in AT. In this paper, we argue that NA and AT cannot be handled independently, since given a dataset, the optimal NA in ST would be no longer optimal in AT. That being said, AT is time-consuming itself; if we directly search NAs in AT over large search spaces, the computation will be practically infeasible. Thus, we propose a diverse-structured network (DS-Net), to significantly reduce the size of the search space: instead of low-level operations, we only consider predefined atomic blocks, where an atomic block is a time-tested building block like the residual block. There are only a few atomic blocks and thus we can weight all atomic blocks rather than find the best one in a searched block of DS-Net, which is an essential trade-off between exploring diverse structures and exploiting the best structures. Empirical results demonstrate the advantages of DS-Net, i.e., weighting the atomic blocks.
Small-group learning is a broadly used methodology in human learning and shows great effectiveness in improving learning outcomes: a small group of students work together towards the same learning objective, where they express their understanding of a topic to their peers, compare their ideas, and help each other to trouble-shoot problems. We are interested in investigating whether this powerful learning technique can be borrowed from humans to improve the learning abilities of machines. We propose a novel learning approach called small-group learning (SGL). In our approach, each learner uses its intermediately trained model to generate a pseudo-labeled dataset and re-trains its model using pseudo-labeled datasets generated by other learners. We propose a multi-level optimization framework to formulate SGL which involves three learning stages: learners train their network weights independently; learners train their network weights collaboratively via mutual pseudo-labeling; learners improve their architectures by minimizing validation losses. We develop an efficient algorithm to solve the SGL problem. We apply our approach to neural architecture search and achieve significant improvement on CIFAR-100, CIFAR-10, and ImageNet.
Humans, as the most powerful learners on the planet, have accumulated a lot of learning skills, such as learning through tests, interleaving learning, self-explanation, active recalling, to name a few. These learning skills and methodologies enable humans to learn new topics more effectively and efficiently. We are interested in investigating whether humans' learning skills can be borrowed to help machines to learn better. Specifically, we aim to formalize these skills and leverage them to train better machine learning (ML) models. To achieve this goal, we develop a general framework -- Skillearn, which provides a principled way to represent humans' learning skills mathematically and use the formally-represented skills to improve the training of ML models. In two case studies, we apply Skillearn to formalize two learning skills of humans: learning by passing tests and interleaving learning, and use the formalized skills to improve neural architecture search. Experiments on various datasets show that trained using the skills formalized by Skillearn, ML models achieve significantly better performance.
Learning through tests is a broadly used methodology in human learning and shows great effectiveness in improving learning outcome: a sequence of tests are made with increasing levels of difficulty; the learner takes these tests to identify his/her weak points in learning and continuously addresses these weak points to successfully pass these tests. We are interested in investigating whether this powerful learning technique can be borrowed from humans to improve the learning abilities of machines. We propose a novel learning approach called learning by passing tests (LPT). In our approach, a tester model creates increasingly more-difficult tests to evaluate a learner model. The learner tries to continuously improve its learning ability so that it can successfully pass however difficult tests created by the tester. We propose a multi-level optimization framework to formulate LPT, where the tester learns to create difficult and meaningful tests and the learner learns to pass these tests. We develop an efficient algorithm to solve the LCT problem. Our method is applied for neural architecture search and achieves significant improvement over state-of-the-art baselines on CIFAR-100, CIFAR-10, and ImageNet.
We study the problem of node classification on graphs with few-shot novel labels, which has two distinctive properties: (1) There are novel labels to emerge in the graph; (2) The novel labels have only a few representative nodes for training a classifier. The study of this problem is instructive and corresponds to many applications such as recommendations for newly formed groups with only a few users in online social networks. To cope with this problem, we propose a novel Meta Transformed Network Embedding framework (MetaTNE), which consists of three modules: (1) A \emph{structural module} provides each node a latent representation according to the graph structure. (2) A \emph{meta-learning module} captures the relationships between the graph structure and the node labels as prior knowledge in a meta-learning manner. Additionally, we introduce an \emph{embedding transformation function} that remedies the deficiency of the straightforward use of meta-learning. Inherently, the meta-learned prior knowledge can be used to facilitate the learning of few-shot novel labels. (3) An \emph{optimization module} employs a simple yet effective scheduling strategy to train the above two modules with a balance between graph structure learning and meta-learning. Experiments on four real-world datasets show that MetaTNE brings a huge improvement over the state-of-the-art methods.
Deep palmprint recognition has become an emerging issue with great potential for personal authentication on handheld and wearable consumer devices. Previous studies of palmprint recognition are mainly based on constrained datasets collected by dedicated devices in controlled environments, which has to reduce the flexibility and convenience. In addition, general deep palmprint recognition algorithms are often too heavy to meet the real-time requirements of embedded system. In this paper, a new palmprint benchmark is established, which consists of more than 20,000 images collected by 5 brands of smart phones in an unconstrained manner. Each image has been manually labeled with 14 key points for region of interest (ROI) extraction. Further, the approach called Deep Distillation Hashing (DDH) is proposed as benchmark for efficient deep palmprint recognition. Palmprint images are converted to binary codes to improve the efficiency of feature matching. Derived from knowledge distillation, novel distillation loss functions are constructed to compress deep model to further improve the efficiency of feature extraction on light network. Comprehensive experiments are conducted on both constrained and unconstrained palmprint databases. Using DDH, the accuracy of palmprint identification can be increased by up to 11.37%, and the Equal Error Rate (EER) of palmprint verification can be reduced by up to 3.11%. The results indicate the feasibility of our database, and DDH can outperform other baselines to achieve the state-of-the-art performance. The collected dataset and related source codes are publicly available at http://gr.xjtu.edu.cn/web/bell/resource.