ImplantFormer: Vision Transformer based Implant Position Regression Using Dental CBCT Data

Implant prosthesis is the most optimum treatment of dentition defect or dentition loss, which usually involves a surgical guide design process to decide the position of implant. However, such design heavily relies on the subjective experiences of dentist. To relieve this problem, in this paper, a transformer based Implant Position Regression Network, ImplantFormer, is proposed to automatically predict the implant position based on the oral CBCT data. The 3D CBCT data is firstly transformed into a series of 2D transverse plane slice views. ImplantFormer is then proposed to predict the position of implant based on the 2D slices of crown images. Convolutional stem and decoder are designed to coarsely extract image feature before the operation of patch embedding and integrate multi-levels feature map for robust prediction. The predictions of our network at tooth crown area are finally projected back to the positions at tooth root. As both long-range relationship and local features are involved, our approach can better represent global information and achieves better location performance than the state-of-the-art detectors. Experimental results on a dataset of 128 patients, collected from Shenzhen University General Hospital, show that our ImplantFormer achieves superior performance than benchmarks.

Synthetic Text Generation with Differential Privacy: A Simple and Practical Recipe

Privacy concerns have attracted increasing attention in data-driven products and services. Existing legislation forbids arbitrary processing of personal data collected from individuals. Generating synthetic versions of such data with a formal privacy guarantee such as differential privacy (DP) is considered to be a solution to address privacy concerns. In this direction, we show a simple, practical, and effective recipe in the text domain: simply fine-tuning a generative language model with DP allows us to generate useful synthetic text while mitigating privacy concerns. Through extensive empirical analyses, we demonstrate that our method produces synthetic data that is competitive in terms of utility with its non-private counterpart and meanwhile provides strong protection against potential privacy leakages.

A Closer Look at the Calibration of Differentially Private Learners

We systematically study the calibration of classifiers trained with differentially private stochastic gradient descent (DP-SGD) and observe miscalibration across a wide range of vision and language tasks. Our analysis identifies per-example gradient clipping in DP-SGD as a major cause of miscalibration, and we show that existing approaches for improving calibration with differential privacy only provide marginal improvements in calibration error while occasionally causing large degradations in accuracy. As a solution, we show that differentially private variants of post-processing calibration methods such as temperature scaling and Platt scaling are surprisingly effective and have negligible utility cost to the overall model. Across 7 tasks, temperature scaling and Platt scaling with DP-SGD result in an average 3.1-fold reduction in the in-domain expected calibration error and only incur at most a minor percent drop in accuracy.

Sample hardness based gradient loss for long-tailed cervical cell detection

Due to the difficulty of cancer samples collection and annotation, cervical cancer datasets usually exhibit a long-tailed data distribution. When training a detector to detect the cancer cells in a WSI (Whole Slice Image) image captured from the TCT (Thinprep Cytology Test) specimen, head categories (e.g. normal cells and inflammatory cells) typically have a much larger number of samples than tail categories (e.g. cancer cells). Most existing state-of-the-art long-tailed learning methods in object detection focus on category distribution statistics to solve the problem in the long-tailed scenario without considering the "hardness" of each sample. To address this problem, in this work we propose a Grad-Libra Loss that leverages the gradients to dynamically calibrate the degree of hardness of each sample for different categories, and re-balance the gradients of positive and negative samples. Our loss can thus help the detector to put more emphasis on those hard samples in both head and tail categories. Extensive experiments on a long-tailed TCT WSI image dataset show that the mainstream detectors, e.g. RepPoints, FCOS, ATSS, YOLOF, etc. trained using our proposed Gradient-Libra Loss, achieved much higher (7.8%) mAP than that trained using cross-entropy classification loss.

When Does Differentially Private Learning Not Suffer in High Dimensions?

Large pretrained models can be privately fine-tuned to achieve performance approaching that of non-private models. A common theme in these results is the surprising observation that high-dimensional models can achieve favorable privacy-utility trade-offs. This seemingly contradicts known results on the model-size dependence of differentially private convex learning and raises the following research question: When does the performance of differentially private learning not degrade with increasing model size? We identify that the magnitudes of gradients projected onto subspaces is a key factor that determines performance. To precisely characterize this for private convex learning, we introduce a condition on the objective that we term restricted Lipschitz continuity and derive improved bounds for the excess empirical and population risks that are dimension-independent under additional conditions. We empirically show that in private fine-tuning of large language models, gradients evaluated near a local optimum are mostly controlled by a few principal components. This behavior is similar to conditions under which we obtain dimension-independent bounds in convex settings. Our theoretical and empirical results together provide a possible explanation for recent successes in large-scale private fine-tuning.

Large Language Models Can Be Strong Differentially Private Learners

Differentially Private (DP) learning has seen limited success for building large deep learning models of text, and attempts at straightforwardly applying Differentially Private Stochastic Gradient Descent (DP-SGD) to NLP tasks have resulted in large performance drops and high computational overhead. We show that this performance drop can be mitigated with (1) the use of large pretrained models; (2) hyperparameters that suit DP optimization; and (3) fine-tuning objectives aligned with the pretraining procedure. With these factors set right, we obtain private NLP models that outperform state-of-the-art private training approaches and strong non-private baselines -- by directly fine-tuning pretrained models with DP optimization on moderately-sized corpora. To address the computational challenge of running DP-SGD with large Transformers, we propose a memory saving technique that allows clipping in DP-SGD to run without instantiating per-example gradients for any layer in the model. The technique enables privately training Transformers with almost the same memory cost as non-private training at a modest run-time overhead. Contrary to conventional wisdom that DP optimization fails at learning high-dimensional models (due to noise that scales with dimension) empirical results reveal that private learning with pretrained models tends to not suffer from dimension-dependent performance degradation.

On the Opportunities and Risks of Foundation Models

AI is undergoing a paradigm shift with the rise of models (e.g., BERT, DALL-E, GPT-3) that are trained on broad data at scale and are adaptable to a wide range of downstream tasks. We call these models foundation models to underscore their critically central yet incomplete character. This report provides a thorough account of the opportunities and risks of foundation models, ranging from their capabilities (e.g., language, vision, robotics, reasoning, human interaction) and technical principles(e.g., model architectures, training procedures, data, systems, security, evaluation, theory) to their applications (e.g., law, healthcare, education) and societal impact (e.g., inequity, misuse, economic and environmental impact, legal and ethical considerations). Though foundation models are based on standard deep learning and transfer learning, their scale results in new emergent capabilities,and their effectiveness across so many tasks incentivizes homogenization. Homogenization provides powerful leverage but demands caution, as the defects of the foundation model are inherited by all the adapted models downstream. Despite the impending widespread deployment of foundation models, we currently lack a clear understanding of how they work, when they fail, and what they are even capable of due to their emergent properties. To tackle these questions, we believe much of the critical research on foundation models will require deep interdisciplinary collaboration commensurate with their fundamentally sociotechnical nature.

Learning from Pseudo Lesion: A Self-supervised Framework for COVID-19 Diagnosis

The Coronavirus disease 2019 (COVID-19) has rapidly spread all over the world since its first report in December 2019 and thoracic computed tomography (CT) has become one of the main tools for its diagnosis. In recent years, deep learning-based approaches have shown impressive performance in myriad image recognition tasks. However, they usually require a large number of annotated data for training. Inspired by Ground Glass Opacity (GGO), a common finding in COIVD-19 patient's CT scans, we proposed in this paper a novel self-supervised pretraining method based on pseudo lesions generation and restoration for COVID-19 diagnosis. We used Perlin noise, a gradient noise based mathematical model, to generate lesion-like patterns, which were then randomly pasted to the lung regions of normal CT images to generate pseudo COVID-19 images. The pairs of normal and pseudo COVID-19 images were then used to train an encoder-decoder architecture based U-Net for image restoration, which does not require any labelled data. The pretrained encoder was then fine-tuned using labelled data for COVID-19 diagnosis task. Two public COVID-19 diagnosis datasets made up of CT images were employed for evaluation. Comprehensive experimental results demonstrated that the proposed self-supervised learning approach could extract better feature representation for COVID-19 diagnosis and the accuracy of the proposed method outperformed the supervised model pretrained on large scale images by 6.57% and 3.03% on SARS-CoV-2 dataset and Jinan COVID-19 dataset, respectively.