WeGA: Weakly-Supervised Global-Local Affinity Learning Framework for Lymph Node Metastasis Prediction in Rectal Cancer

Accurate lymph node metastasis (LNM) assessment in rectal cancer is essential for treatment planning, yet current MRI-based evaluation shows unsatisfactory accuracy, leading to suboptimal clinical decisions. Developing automated systems also faces significant obstacles, primarily the lack of node-level annotations. Previous methods treat lymph nodes as isolated entities rather than as an interconnected system, overlooking valuable spatial and contextual information. To solve this problem, we present WeGA, a novel weakly-supervised global-local affinity learning framework that addresses these challenges through three key innovations: 1) a dual-branch architecture with DINOv2 backbone for global context and residual encoder for local node details; 2) a global-local affinity extractor that aligns features across scales through cross-attention fusion; and 3) a regional affinity loss that enforces structural coherence between classification maps and anatomical regions. Experiments across one internal and two external test centers demonstrate that WeGA outperforms existing methods, achieving AUCs of 0.750, 0.822, and 0.802 respectively. By effectively modeling the relationships between individual lymph nodes and their collective context, WeGA provides a more accurate and generalizable approach for lymph node metastasis prediction, potentially enhancing diagnostic precision and treatment selection for rectal cancer patients.

The ProfessionAl Go annotation datasEt (PAGE)

The game of Go has been highly under-researched due to the lack of game records and analysis tools. In recent years, the increasing number of professional competitions and the advent of AlphaZero-based algorithms provide an excellent opportunity for analyzing human Go games on a large scale. In this paper, we present the ProfessionAl Go annotation datasEt (PAGE), containing 98,525 games played by 2,007 professional players and spans over 70 years. The dataset includes rich AI analysis results for each move. Moreover, PAGE provides detailed metadata for every player and game after manual cleaning and labeling. Beyond the preliminary analysis of the dataset, we provide sample tasks that benefit from our dataset to demonstrate the potential application of PAGE in multiple research directions. To the best of our knowledge, PAGE is the first dataset with extensive annotation in the game of Go. This work is an extended version of [1] where we perform a more detailed description, analysis, and application.