WeGA: Weakly-Supervised Global-Local Affinity Learning Framework for Lymph Node Metastasis Prediction in Rectal Cancer

Accurate lymph node metastasis (LNM) assessment in rectal cancer is essential for treatment planning, yet current MRI-based evaluation shows unsatisfactory accuracy, leading to suboptimal clinical decisions. Developing automated systems also faces significant obstacles, primarily the lack of node-level annotations. Previous methods treat lymph nodes as isolated entities rather than as an interconnected system, overlooking valuable spatial and contextual information. To solve this problem, we present WeGA, a novel weakly-supervised global-local affinity learning framework that addresses these challenges through three key innovations: 1) a dual-branch architecture with DINOv2 backbone for global context and residual encoder for local node details; 2) a global-local affinity extractor that aligns features across scales through cross-attention fusion; and 3) a regional affinity loss that enforces structural coherence between classification maps and anatomical regions. Experiments across one internal and two external test centers demonstrate that WeGA outperforms existing methods, achieving AUCs of 0.750, 0.822, and 0.802 respectively. By effectively modeling the relationships between individual lymph nodes and their collective context, WeGA provides a more accurate and generalizable approach for lymph node metastasis prediction, potentially enhancing diagnostic precision and treatment selection for rectal cancer patients.

ABS-Mamba: SAM2-Driven Bidirectional Spiral Mamba Network for Medical Image Translation

Accurate multi-modal medical image translation requires ha-rmonizing global anatomical semantics and local structural fidelity, a challenge complicated by intermodality information loss and structural distortion. We propose ABS-Mamba, a novel architecture integrating the Segment Anything Model 2 (SAM2) for organ-aware semantic representation, specialized convolutional neural networks (CNNs) for preserving modality-specific edge and texture details, and Mamba's selective state-space modeling for efficient long- and short-range feature dependencies. Structurally, our dual-resolution framework leverages SAM2's image encoder to capture organ-scale semantics from high-resolution inputs, while a parallel CNNs branch extracts fine-grained local features. The Robust Feature Fusion Network (RFFN) integrates these epresentations, and the Bidirectional Mamba Residual Network (BMRN) models spatial dependencies using spiral scanning and bidirectional state-space dynamics. A three-stage skip fusion decoder enhances edge and texture fidelity. We employ Efficient Low-Rank Adaptation (LoRA+) fine-tuning to enable precise domain specialization while maintaining the foundational capabilities of the pre-trained components. Extensive experimental validation on the SynthRAD2023 and BraTS2019 datasets demonstrates that ABS-Mamba outperforms state-of-the-art methods, delivering high-fidelity cross-modal synthesis that preserves anatomical semantics and structural details to enhance diagnostic accuracy in clinical applications. The code is available at https://github.com/gatina-yone/ABS-Mamba

GEOcc: Geometrically Enhanced 3D Occupancy Network with Implicit-Explicit Depth Fusion and Contextual Self-Supervision

3D occupancy perception holds a pivotal role in recent vision-centric autonomous driving systems by converting surround-view images into integrated geometric and semantic representations within dense 3D grids. Nevertheless, current models still encounter two main challenges: modeling depth accurately in the 2D-3D view transformation stage, and overcoming the lack of generalizability issues due to sparse LiDAR supervision. To address these issues, this paper presents GEOcc, a Geometric-Enhanced Occupancy network tailored for vision-only surround-view perception. Our approach is three-fold: 1) Integration of explicit lift-based depth prediction and implicit projection-based transformers for depth modeling, enhancing the density and robustness of view transformation. 2) Utilization of mask-based encoder-decoder architecture for fine-grained semantic predictions; 3) Adoption of context-aware self-training loss functions in the pertaining stage to complement LiDAR supervision, involving the re-rendering of 2D depth maps from 3D occupancy features and leveraging image reconstruction loss to obtain denser depth supervision besides sparse LiDAR ground-truths. Our approach achieves State-Of-The-Art performance on the Occ3D-nuScenes dataset with the least image resolution needed and the most weightless image backbone compared with current models, marking an improvement of 3.3% due to our proposed contributions. Comprehensive experimentation also demonstrates the consistent superiority of our method over baselines and alternative approaches.

Spatial-Temporal Parallel Transformer for Arm-Hand Dynamic Estimation

We propose an approach to estimate arm and hand dynamics from monocular video by utilizing the relationship between arm and hand. Although monocular full human motion capture technologies have made great progress in recent years, recovering accurate and plausible arm twists and hand gestures from in-the-wild videos still remains a challenge. To solve this problem, our solution is proposed based on the fact that arm poses and hand gestures are highly correlated in most real situations. To fully exploit arm-hand correlation as well as inter-frame information, we carefully design a Spatial-Temporal Parallel Arm-Hand Motion Transformer (PAHMT) to predict the arm and hand dynamics simultaneously. We also introduce new losses to encourage the estimations to be smooth and accurate. Besides, we collect a motion capture dataset including 200K frames of hand gestures and use this data to train our model. By integrating a 2D hand pose estimation model and a 3D human pose estimation model, the proposed method can produce plausible arm and hand dynamics from monocular video. Extensive evaluations demonstrate that the proposed method has advantages over previous state-of-the-art approaches and shows robustness under various challenging scenarios.