PharmacyGPT: The AI Pharmacist

In this study, we introduce PharmacyGPT, a novel framework to assess the capabilities of large language models (LLMs) such as ChatGPT and GPT-4 in emulating the role of clinical pharmacists. Our methodology encompasses the utilization of LLMs to generate comprehensible patient clusters, formulate medication plans, and forecast patient outcomes. We conduct our investigation using real data acquired from the intensive care unit (ICU) at the University of North Carolina Chapel Hill (UNC) Hospital. Our analysis offers valuable insights into the potential applications and limitations of LLMs in the field of clinical pharmacy, with implications for both patient care and the development of future AI-driven healthcare solutions. By evaluating the performance of PharmacyGPT, we aim to contribute to the ongoing discourse surrounding the integration of artificial intelligence in healthcare settings, ultimately promoting the responsible and efficacious use of such technologies.

RetouchingFFHQ: A Large-scale Dataset for Fine-grained Face Retouching Detection

The widespread use of face retouching filters on short-video platforms has raised concerns about the authenticity of digital appearances and the impact of deceptive advertising. To address these issues, there is a pressing need to develop advanced face retouching techniques. However, the lack of large-scale and fine-grained face retouching datasets has been a major obstacle to progress in this field. In this paper, we introduce RetouchingFFHQ, a large-scale and fine-grained face retouching dataset that contains over half a million conditionally-retouched images. RetouchingFFHQ stands out from previous datasets due to its large scale, high quality, fine-grainedness, and customization. By including four typical types of face retouching operations and different retouching levels, we extend the binary face retouching detection into a fine-grained, multi-retouching type, and multi-retouching level estimation problem. Additionally, we propose a Multi-granularity Attention Module (MAM) as a plugin for CNN backbones for enhanced cross-scale representation learning. Extensive experiments using different baselines as well as our proposed method on RetouchingFFHQ show decent performance on face retouching detection. With the proposed new dataset, we believe there is great potential for future work to tackle the challenging problem of real-world fine-grained face retouching detection.

Towards Deep Network Steganography: From Networks to Networks

With the widespread applications of the deep neural network (DNN), how to covertly transmit the DNN models in public channels brings us the attention, especially for those trained for secret-learning tasks. In this paper, we propose deep network steganography for the covert communication of DNN models. Unlike the existing steganography schemes which focus on the subtle modification of the cover data to accommodate the secrets, our scheme is learning task oriented, where the learning task of the secret DNN model (termed as secret-learning task) is disguised into another ordinary learning task conducted in a stego DNN model (termed as stego-learning task). To this end, we propose a gradient-based filter insertion scheme to insert interference filters into the important positions in the secret DNN model to form a stego DNN model. These positions are then embedded into the stego DNN model using a key by side information hiding. Finally, we activate the interference filters by a partial optimization strategy, such that the generated stego DNN model works on the stego-learning task. We conduct the experiments on both the intra-task steganography and inter-task steganography (i.e., the secret and stego-learning tasks belong to the same and different categories), both of which demonstrate the effectiveness of our proposed method for covert communication of DNN models.

Identification of Causal Relationship between Amyloid-beta Accumulation and Alzheimer's Disease Progression via Counterfactual Inference

Alzheimer's disease (AD) is a neurodegenerative disorder that is beginning with amyloidosis, followed by neuronal loss and deterioration in structure, function, and cognition. The accumulation of amyloid-beta in the brain, measured through 18F-florbetapir (AV45) positron emission tomography (PET) imaging, has been widely used for early diagnosis of AD. However, the relationship between amyloid-beta accumulation and AD pathophysiology remains unclear, and causal inference approaches are needed to uncover how amyloid-beta levels can impact AD development. In this paper, we propose a graph varying coefficient neural network (GVCNet) for estimating the individual treatment effect with continuous treatment levels using a graph convolutional neural network. We highlight the potential of causal inference approaches, including GVCNet, for measuring the regional causal connections between amyloid-beta accumulation and AD pathophysiology, which may serve as a robust tool for early diagnosis and tailored care.

Exploring New Frontiers in Agricultural NLP: Investigating the Potential of Large Language Models for Food Applications

This paper explores new frontiers in agricultural natural language processing by investigating the effectiveness of using food-related text corpora for pretraining transformer-based language models. In particular, we focus on the task of semantic matching, which involves establishing mappings between food descriptions and nutrition data. To accomplish this, we fine-tune a pre-trained transformer-based language model, AgriBERT, on this task, utilizing an external source of knowledge, such as the FoodOn ontology. To advance the field of agricultural NLP, we propose two new avenues of exploration: (1) utilizing GPT-based models as a baseline and (2) leveraging ChatGPT as an external source of knowledge. ChatGPT has shown to be a strong baseline in many NLP tasks, and we believe it has the potential to improve our model in the task of semantic matching and enhance our model's understanding of food-related concepts and relationships. Additionally, we experiment with other applications, such as cuisine prediction based on food ingredients, and expand the scope of our research to include other NLP tasks beyond semantic matching. Overall, this paper provides promising avenues for future research in this field, with potential implications for improving the performance of agricultural NLP applications.

AD-AutoGPT: An Autonomous GPT for Alzheimer's Disease Infodemiology

In this pioneering study, inspired by AutoGPT, the state-of-the-art open-source application based on the GPT-4 large language model, we develop a novel tool called AD-AutoGPT which can conduct data collection, processing, and analysis about complex health narratives of Alzheimer's Disease in an autonomous manner via users' textual prompts. We collated comprehensive data from a variety of news sources, including the Alzheimer's Association, BBC, Mayo Clinic, and the National Institute on Aging since June 2022, leading to the autonomous execution of robust trend analyses, intertopic distance maps visualization, and identification of salient terms pertinent to Alzheimer's Disease. This approach has yielded not only a quantifiable metric of relevant discourse but also valuable insights into public focus on Alzheimer's Disease. This application of AD-AutoGPT in public health signifies the transformative potential of AI in facilitating a data-rich understanding of complex health narratives like Alzheimer's Disease in an autonomous manner, setting the groundwork for future AI-driven investigations in global health landscapes.

Towards Speech Dialogue Translation Mediating Speakers of Different Languages

We present a new task, speech dialogue translation mediating speakers of different languages. We construct the SpeechBSD dataset for the task and conduct baseline experiments. Furthermore, we consider context to be an important aspect that needs to be addressed in this task and propose two ways of utilizing context, namely monolingual context and bilingual context. We conduct cascaded speech translation experiments using Whisper and mBART, and show that bilingual context performs better in our settings.

pTSE: A Multi-model Ensemble Method for Probabilistic Time Series Forecasting

Various probabilistic time series forecasting models have sprung up and shown remarkably good performance. However, the choice of model highly relies on the characteristics of the input time series and the fixed distribution that the model is based on. Due to the fact that the probability distributions cannot be averaged over different models straightforwardly, the current time series model ensemble methods cannot be directly applied to improve the robustness and accuracy of forecasting. To address this issue, we propose pTSE, a multi-model distribution ensemble method for probabilistic forecasting based on Hidden Markov Model (HMM). pTSE only takes off-the-shelf outputs from member models without requiring further information about each model. Besides, we provide a complete theoretical analysis of pTSE to prove that the empirical distribution of time series subject to an HMM will converge to the stationary distribution almost surely. Experiments on benchmarks show the superiority of pTSE overall member models and competitive ensemble methods.

Generative Steganographic Flow

Generative steganography (GS) is a new data hiding manner, featuring direct generation of stego media from secret data. Existing GS methods are generally criticized for their poor performances. In this paper, we propose a novel flow based GS approach -- Generative Steganographic Flow (GSF), which provides direct generation of stego images without cover image. We take the stego image generation and secret data recovery process as an invertible transformation, and build a reversible bijective mapping between input secret data and generated stego images. In the forward mapping, secret data is hidden in the input latent of Glow model to generate stego images. By reversing the mapping, hidden data can be extracted exactly from generated stego images. Furthermore, we propose a novel latent optimization strategy to improve the fidelity of stego images. Experimental results show our proposed GSF has far better performances than SOTA works.

Generative Steganography Diffusion

Generative steganography (GS) is an emerging technique that generates stego images directly from secret data. Various GS methods based on GANs or Flow have been developed recently. However, existing GAN-based GS methods cannot completely recover the hidden secret data due to the lack of network invertibility, while Flow-based methods produce poor image quality due to the stringent reversibility restriction in each module. To address this issue, we propose a novel GS scheme called "Generative Steganography Diffusion" (GSD) by devising an invertible diffusion model named "StegoDiffusion". It not only generates realistic stego images but also allows for 100\% recovery of the hidden secret data. The proposed StegoDiffusion model leverages a non-Markov chain with a fast sampling technique to achieve efficient stego image generation. By constructing an ordinary differential equation (ODE) based on the transition probability of the generation process in StegoDiffusion, secret data and stego images can be converted to each other through the approximate solver of ODE -- Euler iteration formula, enabling the use of irreversible but more expressive network structures to achieve model invertibility. Our proposed GSD has the advantages of both reversibility and high performance, significantly outperforming existing GS methods in all metrics.