Enhancing Visually-Rich Document Understanding via Layout Structure Modeling

In recent years, the use of multi-modal pre-trained Transformers has led to significant advancements in visually-rich document understanding. However, existing models have mainly focused on features such as text and vision while neglecting the importance of layout relationship between text nodes. In this paper, we propose GraphLayoutLM, a novel document understanding model that leverages the modeling of layout structure graph to inject document layout knowledge into the model. GraphLayoutLM utilizes a graph reordering algorithm to adjust the text sequence based on the graph structure. Additionally, our model uses a layout-aware multi-head self-attention layer to learn document layout knowledge. The proposed model enables the understanding of the spatial arrangement of text elements, improving document comprehension. We evaluate our model on various benchmarks, including FUNSD, XFUND and CORD, and achieve state-of-the-art results among these datasets. Our experimental results demonstrate that our proposed method provides a significant improvement over existing approaches and showcases the importance of incorporating layout information into document understanding models. We also conduct an ablation study to investigate the contribution of each component of our model. The results show that both the graph reordering algorithm and the layout-aware multi-head self-attention layer play a crucial role in achieving the best performance.

Domain Randomization-Enhanced Depth Simulation and Restoration for Perceiving and Grasping Specular and Transparent Objects

Commercial depth sensors usually generate noisy and missing depths, especially on specular and transparent objects, which poses critical issues to downstream depth or point cloud-based tasks. To mitigate this problem, we propose a powerful RGBD fusion network, SwinDRNet, for depth restoration. We further propose Domain Randomization-Enhanced Depth Simulation (DREDS) approach to simulate an active stereo depth system using physically based rendering and generate a large-scale synthetic dataset that contains 130K photorealistic RGB images along with their simulated depths carrying realistic sensor noises. To evaluate depth restoration methods, we also curate a real-world dataset, namely STD, that captures 30 cluttered scenes composed of 50 objects with different materials from specular, transparent, to diffuse. Experiments demonstrate that the proposed DREDS dataset bridges the sim-to-real domain gap such that, trained on DREDS, our SwinDRNet can seamlessly generalize to other real depth datasets, e.g. ClearGrasp, and outperform the competing methods on depth restoration with a real-time speed. We further show that our depth restoration effectively boosts the performance of downstream tasks, including category-level pose estimation and grasping tasks. Our data and code are available at https://github.com/PKU-EPIC/DREDS

Discovering Clinically Meaningful Shape Features for the Analysis of Tumor Pathology Images

With the advanced imaging technology, digital pathology imaging of tumor tissue slides is becoming a routine clinical procedure for cancer diagnosis. This process produces massive imaging data that capture histological details in high resolution. Recent developments in deep-learning methods have enabled us to automatically detect and characterize the tumor regions in pathology images at large scale. From each identified tumor region, we extracted 30 well-defined descriptors that quantify its shape, geometry, and topology. We demonstrated how those descriptor features were associated with patient survival outcome in lung adenocarcinoma patients from the National Lung Screening Trial (n=143). Besides, a descriptor-based prognostic model was developed and validated in an independent patient cohort from The Cancer Genome Atlas Program program (n=318). This study proposes new insights into the relationship between tumor shape, geometrical, and topological features and patient prognosis. We provide software in the form of R code on GitHub: https://github.com/estfernandez/Slide_Image_Segmentation_and_Extraction.

Predicting survival outcomes using topological features of tumor pathology images

Tumor shape and size have been used as important markers for cancer diagnosis and treatment. Recent developments in medical imaging technology enable more detailed segmentation of tumor regions in high resolution. This paper proposes a topological feature to characterize tumor progression from digital pathology images and examine its effect on the time-to-event data. We develop distance transform for pathology images and show that a topological summary statistic computed by persistent homology quantifies tumor shape, size, distribution, and connectivity. The topological features are represented in functional space and used as functional predictors in a functional Cox regression model. A case study is conducted using non-small cell lung cancer pathology images. The results show that the topological features predict survival prognosis after adjusting for age, sex, smoking status, stage, and size of tumors. Also, the topological features with non-zero effects correspond to the shapes that are known to be related to tumor progression. Our study provides a new perspective for understanding tumor shape and patient prognosis.