PDF: A Probability-Driven Framework for Open World 3D Point Cloud Semantic Segmentation

Existing point cloud semantic segmentation networks cannot identify unknown classes and update their knowledge, due to a closed-set and static perspective of the real world, which would induce the intelligent agent to make bad decisions. To address this problem, we propose a Probability-Driven Framework (PDF) for open world semantic segmentation that includes (i) a lightweight U-decoder branch to identify unknown classes by estimating the uncertainties, (ii) a flexible pseudo-labeling scheme to supply geometry features along with probability distribution features of unknown classes by generating pseudo labels, and (iii) an incremental knowledge distillation strategy to incorporate novel classes into the existing knowledge base gradually. Our framework enables the model to behave like human beings, which could recognize unknown objects and incrementally learn them with the corresponding knowledge. Experimental results on the S3DIS and ScanNetv2 datasets demonstrate that the proposed PDF outperforms other methods by a large margin in both important tasks of open world semantic segmentation.

MENTOR: Multi-level Self-supervised Learning for Multimodal Recommendation

With the increasing multimedia information, multimodal recommendation has received extensive attention. It utilizes multimodal information to alleviate the data sparsity problem in recommendation systems, thus improving recommendation accuracy. However, the reliance on labeled data severely limits the performance of multimodal recommendation models. Recently, self-supervised learning has been used in multimodal recommendations to mitigate the label sparsity problem. Nevertheless, the state-of-the-art methods cannot avoid the modality noise when aligning multimodal information due to the large differences in the distributions of different modalities. To this end, we propose a Multi-level sElf-supervised learNing for mulTimOdal Recommendation (MENTOR) method to address the label sparsity problem and the modality alignment problem. Specifically, MENTOR first enhances the specific features of each modality using the graph convolutional network (GCN) and fuses the visual and textual modalities. It then enhances the item representation via the item semantic graph for all modalities, including the fused modality. Then, it introduces two multilevel self-supervised tasks: the multilevel cross-modal alignment task and the general feature enhancement task. The multilevel cross-modal alignment task aligns each modality under the guidance of the ID embedding from multiple levels while maintaining the historical interaction information. The general feature enhancement task enhances the general feature from both the graph and feature perspectives to improve the robustness of our model. Extensive experiments on three publicly available datasets demonstrate the effectiveness of our method. Our code is publicly available at https://github.com/Jinfeng-Xu/MENTOR.

Dual-Reference Source-Free Active Domain Adaptation for Nasopharyngeal Carcinoma Tumor Segmentation across Multiple Hospitals

Nasopharyngeal carcinoma (NPC) is a prevalent and clinically significant malignancy that predominantly impacts the head and neck area. Precise delineation of the Gross Tumor Volume (GTV) plays a pivotal role in ensuring effective radiotherapy for NPC. Despite recent methods that have achieved promising results on GTV segmentation, they are still limited by lacking carefully-annotated data and hard-to-access data from multiple hospitals in clinical practice. Although some unsupervised domain adaptation (UDA) has been proposed to alleviate this problem, unconditionally mapping the distribution distorts the underlying structural information, leading to inferior performance. To address this challenge, we devise a novel Sourece-Free Active Domain Adaptation (SFADA) framework to facilitate domain adaptation for the GTV segmentation task. Specifically, we design a dual reference strategy to select domain-invariant and domain-specific representative samples from a specific target domain for annotation and model fine-tuning without relying on source-domain data. Our approach not only ensures data privacy but also reduces the workload for oncologists as it just requires annotating a few representative samples from the target domain and does not need to access the source data. We collect a large-scale clinical dataset comprising 1057 NPC patients from five hospitals to validate our approach. Experimental results show that our method outperforms the UDA methods and achieves comparable results to the fully supervised upper bound, even with few annotations, highlighting the significant medical utility of our approach. In addition, there is no public dataset about multi-center NPC segmentation, we will release code and dataset for future research.

CasFusionNet: A Cascaded Network for Point Cloud Semantic Scene Completion by Dense Feature Fusion

Semantic scene completion (SSC) aims to complete a partial 3D scene and predict its semantics simultaneously. Most existing works adopt the voxel representations, thus suffering from the growth of memory and computation cost as the voxel resolution increases. Though a few works attempt to solve SSC from the perspective of 3D point clouds, they have not fully exploited the correlation and complementarity between the two tasks of scene completion and semantic segmentation. In our work, we present CasFusionNet, a novel cascaded network for point cloud semantic scene completion by dense feature fusion. Specifically, we design (i) a global completion module (GCM) to produce an upsampled and completed but coarse point set, (ii) a semantic segmentation module (SSM) to predict the per-point semantic labels of the completed points generated by GCM, and (iii) a local refinement module (LRM) to further refine the coarse completed points and the associated labels from a local perspective. We organize the above three modules via dense feature fusion in each level, and cascade a total of four levels, where we also employ feature fusion between each level for sufficient information usage. Both quantitative and qualitative results on our compiled two point-based datasets validate the effectiveness and superiority of our CasFusionNet compared to state-of-the-art methods in terms of both scene completion and semantic segmentation. The codes and datasets are available at: https://github.com/JinfengX/CasFusionNet.

Improving Feature Extraction from Histopathological Images Through A Fine-tuning ImageNet Model

Due to lack of annotated pathological images, transfer learning has been the predominant approach in the field of digital pathology.Pre-trained neural networks based on ImageNet database are often used to extract "off the shelf" features, achieving great success in predicting tissue types, molecular features, and clinical outcomes, etc. We hypothesize that fine-tuning the pre-trained models using histopathological images could further improve feature extraction, and downstream prediction performance.We used 100,000 annotated HE image patches for colorectal cancer (CRC) to finetune a pretrained Xception model via a twostep approach.The features extracted from finetuned Xception (FTX2048) model and Imagepretrained (IMGNET2048) model were compared through: (1) tissue classification for HE images from CRC, same image type that was used for finetuning; (2) prediction of immunerelated gene expression and (3) gene mutations for lung adenocarcinoma (LUAD).Fivefold cross validation was used for model performance evaluation. The extracted features from the finetuned FTX2048 exhibited significantly higher accuracy for predicting tisue types of CRC compared to the off the shelf feature directly from Xception based on ImageNet database. Particularly, FTX2048 markedly improved the accuracy for stroma from 87% to 94%. Similarly, features from FTX2048 boosted the prediction of transcriptomic expression of immunerelated genesin LUAD. For the genes that had signigicant relationships with image fetures, the features fgrom the finetuned model imprroved the prediction for the majority of the genes. Inaddition, fetures from FTX2048 improved prediction of mutation for 5 out of 9 most frequently mutated genes in LUAD.

Learning Latent Features with Pairwise Penalties in Matrix Completion

Low-rank matrix completion (MC) has achieved great success in many real-world data applications. A latent feature model formulation is usually employed and, to improve prediction performance, the similarities between latent variables can be exploited by pairwise learning, e.g., the graph regularized matrix factorization (GRMF) method. However, existing GRMF approaches often use a squared L2 norm to measure the pairwise difference, which may be overly influenced by dissimilar pairs and lead to inferior prediction. To fully empower pairwise learning for matrix completion, we propose a general optimization framework that allows a rich class of (non-)convex pairwise penalty functions. A new and efficient algorithm is further developed to uniformly solve the optimization problem, with a theoretical convergence guarantee. In an important situation where the latent variables form a small number of subgroups, its statistical guarantee is also fully characterized. In particular, we theoretically characterize the complexity-regularized maximum likelihood estimator, as a special case of our framework. It has a better error bound when compared to the standard trace-norm regularized matrix completion. We conduct extensive experiments on both synthetic and real datasets to demonstrate the superior performance of this general framework.

On Scalable Inference with Stochastic Gradient Descent

In many applications involving large dataset or online updating, stochastic gradient descent (SGD) provides a scalable way to compute parameter estimates and has gained increasing popularity due to its numerical convenience and memory efficiency. While the asymptotic properties of SGD-based estimators have been established decades ago, statistical inference such as interval estimation remains much unexplored. The traditional resampling method such as the bootstrap is not computationally feasible since it requires to repeatedly draw independent samples from the entire dataset. The plug-in method is not applicable when there are no explicit formulas for the covariance matrix of the estimator. In this paper, we propose a scalable inferential procedure for stochastic gradient descent, which, upon the arrival of each observation, updates the SGD estimate as well as a large number of randomly perturbed SGD estimates. The proposed method is easy to implement in practice. We establish its theoretical properties for a general class of models that includes generalized linear models and quantile regression models as special cases. The finite-sample performance and numerical utility is evaluated by simulation studies and two real data applications.