Multimodal Federated Learning: A Survey through the Lens of Different FL Paradigms

Multimodal Federated Learning (MFL) lies at the intersection of two pivotal research areas: leveraging complementary information from multiple modalities to improve downstream inference performance and enabling distributed training to enhance efficiency and preserve privacy. Despite the growing interest in MFL, there is currently no comprehensive taxonomy that organizes MFL through the lens of different Federated Learning (FL) paradigms. This perspective is important because multimodal data introduces distinct challenges across various FL settings. These challenges, including modality heterogeneity, privacy heterogeneity, and communication inefficiency, are fundamentally different from those encountered in traditional unimodal or non-FL scenarios. In this paper, we systematically examine MFL within the context of three major FL paradigms: horizontal FL (HFL), vertical FL (VFL), and hybrid FL. For each paradigm, we present the problem formulation, review representative training algorithms, and highlight the most prominent challenge introduced by multimodal data in distributed settings. We also discuss open challenges and provide insights for future research. By establishing this taxonomy, we aim to uncover the novel challenges posed by multimodal data from the perspective of different FL paradigms and to offer a new lens through which to understand and advance the development of MFL.

Robust Secure Communications in Near-Field ISCAP Systems with Extremely Large-Scale Antenna Array

This paper investigates robust secure communications in a near-field integrated sensing, communication, and powering (ISCAP) system, in which the base station (BS) is equipped with an extremely large-scale antenna array (ELAA). In this system, the BS transmits confidential messages to a single legitimate communication user (CU), simultaneously providing wireless power transfer to multiple energy receivers (ERs) and performing point target sensing. We consider a scenario in which both the ERs and the sensing target may act as potential eavesdroppers attempting to intercept the confidential messages. To safeguard secure communication, the BS employs a joint beamforming design by transmitting information beams combined with dedicated triple-purpose beams serving as energy and sensing signals, as well as artificial noise (AN) for effectively jamming potential eavesdroppers. It is assumed that only coarse location information of the ERs and sensing targets or eavesdroppers is available at the BS, leading to imperfect channel state information (CSI). Under this setup, we formulate a robust beamforming optimization problem with the objective of maximizing the secrecy rate for the CU, while ensuring worst-case performance requirements on both target sensing and wireless energy harvesting at the ERs. To address the non-convex robust joint beamforming problem and facilitate the deployment of a low-complexity algorithm, we employ the S-procedure alongside an eavesdropping CSI error-bound determination method to acquire a high-quality solution.

The Final Layer Holds the Key: A Unified and Efficient GNN Calibration Framework

Graph Neural Networks (GNNs) have demonstrated remarkable effectiveness on graph-based tasks. However, their predictive confidence is often miscalibrated, typically exhibiting under-confidence, which harms the reliability of their decisions. Existing calibration methods for GNNs normally introduce additional calibration components, which fail to capture the intrinsic relationship between the model and the prediction confidence, resulting in limited theoretical guarantees and increased computational overhead. To address this issue, we propose a simple yet efficient graph calibration method. We establish a unified theoretical framework revealing that model confidence is jointly governed by class-centroid-level and node-level calibration at the final layer. Based on this insight, we theoretically show that reducing the weight decay of the final-layer parameters alleviates GNN under-confidence by acting on the class-centroid level, while node-level calibration acts as a finer-grained complement to class-centroid level calibration, which encourages each test node to be closer to its predicted class centroid at the final-layer representations. Extensive experiments validate the superiority of our method.

Sensing-Assisted Channel Prediction in Complex Wireless Environments: An LLM-Based Approach

This letter studies the sensing-assisted channel prediction for a multi-antenna orthogonal frequency division multiplexing (OFDM) system operating in realistic and complex wireless environments. In this system,an integrated sensing and communication (ISAC) transmitter leverages the mono-static sensing capability to facilitate the prediction of its bi-static communication channel, by exploiting the fact that the sensing and communication channels share the same physical environment involving shared scatterers. Specifically, we propose a novel large language model (LLM)-based channel prediction approach,which adapts pre-trained text-based LLM to handle the complex-matrix-form channel state information (CSI) data. This approach utilizes the LLM's strong ability to capture the intricate spatiotemporal relationships between the multi-path sensing and communication channels, and thus efficiently predicts upcoming communication CSI based on historical communication and sensing CSI data. Experimental results show that the proposed LLM-based approach significantly outperforms conventional deep learning-based methods and the benchmark scheme without sensing assistance.

The Larger the Merrier? Efficient Large AI Model Inference in Wireless Edge Networks

The growing demand for large artificial intelligence model (LAIM) services is driving a paradigm shift from traditional cloud-based inference to edge-based inference for low-latency, privacy-preserving applications. In particular, edge-device co-inference, which partitions LAIMs between edge devices and servers, has emerged as a promising strategy for resource-efficient LAIM execution in wireless networks. In this paper, we investigate a pruning-aware LAIM co-inference scheme, where a pre-trained LAIM is pruned and partitioned into on-device and on-server sub-models for deployment. For analysis, we first prove that the LAIM output distortion is upper bounded by its parameter distortion. Then, we derive a lower bound on parameter distortion via rate-distortion theory, analytically capturing the relationship between pruning ratio and co-inference performance. Next, based on the analytical results, we formulate an LAIM co-inference distortion bound minimization problem by jointly optimizing the pruning ratio, transmit power, and computation frequency under system latency, energy, and available resource constraints. Moreover, we propose an efficient algorithm to tackle the considered highly non-convex problem. Finally, extensive simulations demonstrate the effectiveness of the proposed design. In particular, model parameter distortion is shown to provide a reliable bound on output distortion. Also, the proposed joint pruning ratio and resource management design achieves superior performance in balancing trade-offs among inference performance, system latency, and energy consumption compared with benchmark schemes, such as fully on-device and on-server inference. Moreover, the split point is shown to play a critical role in system performance optimization under heterogeneous and resource-limited edge environments.

An integrated language-vision foundation model for conversational diagnostics and triaging in primary eye care

Current deep learning models are mostly task specific and lack a user-friendly interface to operate. We present Meta-EyeFM, a multi-function foundation model that integrates a large language model (LLM) with vision foundation models (VFMs) for ocular disease assessment. Meta-EyeFM leverages a routing mechanism to enable accurate task-specific analysis based on text queries. Using Low Rank Adaptation, we fine-tuned our VFMs to detect ocular and systemic diseases, differentiate ocular disease severity, and identify common ocular signs. The model achieved 100% accuracy in routing fundus images to appropriate VFMs, which achieved $\ge$ 82.2% accuracy in disease detection, $\ge$ 89% in severity differentiation, $\ge$ 76% in sign identification. Meta-EyeFM was 11% to 43% more accurate than Gemini-1.5-flash and ChatGPT-4o LMMs in detecting various eye diseases and comparable to an ophthalmologist. This system offers enhanced usability and diagnostic performance, making it a valuable decision support tool for primary eye care or an online LLM for fundus evaluation.

Benchmarking Ethical and Safety Risks of Healthcare LLMs in China-Toward Systemic Governance under Healthy China 2030

Large Language Models (LLMs) are poised to transform healthcare under China's Healthy China 2030 initiative, yet they introduce new ethical and patient-safety challenges. We present a novel 12,000-item Q&A benchmark covering 11 ethics and 9 safety dimensions in medical contexts, to quantitatively evaluate these risks. Using this dataset, we assess state-of-the-art Chinese medical LLMs (e.g., Qwen 2.5-32B, DeepSeek), revealing moderate baseline performance (accuracy 42.7% for Qwen 2.5-32B) and significant improvements after fine-tuning on our data (up to 50.8% accuracy). Results show notable gaps in LLM decision-making on ethics and safety scenarios, reflecting insufficient institutional oversight. We then identify systemic governance shortfalls-including the lack of fine-grained ethical audit protocols, slow adaptation by hospital IRBs, and insufficient evaluation tools-that currently hinder safe LLM deployment. Finally, we propose a practical governance framework for healthcare institutions (embedding LLM auditing teams, enacting data ethics guidelines, and implementing safety simulation pipelines) to proactively manage LLM risks. Our study highlights the urgent need for robust LLM governance in Chinese healthcare, aligning AI innovation with patient safety and ethical standards.

Building a Human-Verified Clinical Reasoning Dataset via a Human LLM Hybrid Pipeline for Trustworthy Medical AI

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the predominant reliance of current medical LLMs on corpora from scientific literature or synthetic data, which often lack the granular expert validation and high clinical relevance essential for advancing their specialized medical capabilities. To address these critical gaps, we introduce a highly clinically relevant dataset with 31,247 medical question-answer pairs, each accompanied by expert-validated chain-of-thought (CoT) explanations. This resource, spanning multiple clinical domains, was curated via a scalable human-LLM hybrid pipeline: LLM-generated rationales were iteratively reviewed, scored, and refined by medical experts against a structured rubric, with substandard outputs revised through human effort or guided LLM regeneration until expert consensus. This publicly available dataset provides a vital source for the development of medical LLMs that capable of transparent and verifiable reasoning, thereby advancing safer and more interpretable AI in medicine.

Federated Causal Inference in Healthcare: Methods, Challenges, and Applications

Federated causal inference enables multi-site treatment effect estimation without sharing individual-level data, offering a privacy-preserving solution for real-world evidence generation. However, data heterogeneity across sites, manifested in differences in covariate, treatment, and outcome, poses significant challenges for unbiased and efficient estimation. In this paper, we present a comprehensive review and theoretical analysis of federated causal effect estimation across both binary/continuous and time-to-event outcomes. We classify existing methods into weight-based strategies and optimization-based frameworks and further discuss extensions including personalized models, peer-to-peer communication, and model decomposition. For time-to-event outcomes, we examine federated Cox and Aalen-Johansen models, deriving asymptotic bias and variance under heterogeneity. Our analysis reveals that FedProx-style regularization achieves near-optimal bias-variance trade-offs compared to naive averaging and meta-analysis. We review related software tools and conclude by outlining opportunities, challenges, and future directions for scalable, fair, and trustworthy federated causal inference in distributed healthcare systems.

A Survey on Parameter-Efficient Fine-Tuning for Foundation Models in Federated Learning

Foundation models have revolutionized artificial intelligence by providing robust, versatile architectures pre-trained on large-scale datasets. However, adapting these massive models to specific downstream tasks requires fine-tuning, which can be prohibitively expensive in computational resources. Parameter-Efficient Fine-Tuning (PEFT) methods address this challenge by selectively updating only a small subset of parameters. Meanwhile, Federated Learning (FL) enables collaborative model training across distributed clients without sharing raw data, making it ideal for privacy-sensitive applications. This survey provides a comprehensive review of the integration of PEFT techniques within federated learning environments. We systematically categorize existing approaches into three main groups: Additive PEFT (which introduces new trainable parameters), Selective PEFT (which fine-tunes only subsets of existing parameters), and Reparameterized PEFT (which transforms model architectures to enable efficient updates). For each category, we analyze how these methods address the unique challenges of federated settings, including data heterogeneity, communication efficiency, computational constraints, and privacy concerns. We further organize the literature based on application domains, covering both natural language processing and computer vision tasks. Finally, we discuss promising research directions, including scaling to larger foundation models, theoretical analysis of federated PEFT methods, and sustainable approaches for resource-constrained environments.