LoASR-Bench: Evaluating Large Speech Language Models on Low-Resource Automatic Speech Recognition Across Language Families

Large language models (LLMs) have driven substantial advances in speech language models (SpeechLMs), yielding strong performance in automatic speech recognition (ASR) under high-resource conditions. However, existing benchmarks predominantly focus on high-resource languages, leaving the ASR behavior of SpeechLMs in low-resource languages insufficiently understood. This gap is critical, as practical ASR systems must reliably support low-resource languages and generalize across diverse language families, and it directly hinders the deployment of SpeechLM-based ASR in real-world multilingual scenarios. As a result, it is essential to evaluate SpeechLMs on low-resource languages to ensure their generalizability across different language families. To address this problem, we propose \textbf{LoASR-Bench}, a comprehensive benchmark designed to evaluate \textbf{lo}w-resource \textbf{a}utomatic \textbf{s}peech \textbf{r}ecognition (\textbf{ASR}) of the latest SpeechLMs across diverse language families. LoASR-Bench comprises 25 languages from 9 language families, featuring both Latin and non-Latin scripts, enabling cross-linguistic and cross-script assessment of ASR performance of current SpeechLMs. Experimental results highlight the limitations of the latest SpeechLMs in handling real-world low-resource languages.

Towards Safer Large Reasoning Models by Promoting Safety Decision-Making before Chain-of-Thought Generation

Large reasoning models (LRMs) achieved remarkable performance via chain-of-thought (CoT), but recent studies showed that such enhanced reasoning capabilities are at the expense of significantly degraded safety capabilities. In this paper, we reveal that LRMs' safety degradation occurs only after CoT is enabled, and this degradation is not observed when CoT is disabled. This observation motivates us to consider encouraging LRMs to make safety decisions before CoT generation. To this end, we propose a novel safety alignment method that promotes the safety decision-making of LRMs before starting CoT generation. Specifically, we first utilize a Bert-based classifier to extract safety decision signals from a safe model (e.g., a CoT-disabled LRM) and then integrate these signals into LRMs' safety alignment as auxiliary supervision. In this way, the safety gradients can be backpropagated to the LRMs' latent representations, effectively strengthening the LRMs' safety decision-making abilities against CoT generation. Extensive experiments demonstrate that our method substantially improves the safety capabilities of LRMs while effectively maintaining LRMs' general reasoning performance.

An Automated Radiomics Framework for Postoperative Survival Prediction in Colorectal Liver Metastases using Preoperative MRI

While colorectal liver metastasis (CRLM) is potentially curable via hepatectomy, patient outcomes remain highly heterogeneous. Postoperative survival prediction is necessary to avoid non-beneficial surgeries and guide personalized therapy. In this study, we present an automated AI-based framework for postoperative CRLM survival prediction using pre- and post-contrast MRI. We performed a retrospective study of 227 CRLM patients who had gadoxetate-enhanced MRI prior to curative-intent hepatectomy between 2013 and 2020. We developed a survival prediction framework comprising an anatomy-aware segmentation pipeline followed by a radiomics pipeline. The segmentation pipeline learns liver, CRLMs, and spleen segmentation from partially-annotated data, leveraging promptable foundation models to generate pseudo-labels. To support this pipeline, we propose SAMONAI, a prompt propagation algorithm that extends Segment Anything Model to 3D point-based segmentation. Predicted pre- and post-contrast segmentations are then fed into our radiomics pipeline, which extracts per-tumor features and predicts survival using SurvAMINN, an autoencoder-based multiple instance neural network for time-to-event survival prediction. SurvAMINN jointly learns dimensionality reduction and survival prediction from right-censored data, emphasizing high-risk metastases. We compared our framework against established methods and biomarkers using univariate and multivariate Cox regression. Our segmentation pipeline achieves median Dice scores of 0.96 (liver) and 0.93 (spleen), driving a CRLM segmentation Dice score of 0.78 and a detection F1-score of 0.79. Accurate segmentation enables our radiomics pipeline to achieve a survival prediction C-index of 0.69. Our results show the potential of integrating segmentation algorithms with radiomics-based survival analysis to deliver accurate and automated CRLM outcome prediction.

Teaching pathology foundation models to accurately predict gene expression with parameter efficient knowledge transfer

Gene expression profiling provides critical insights into cellular heterogeneity, biological processes and disease mechanisms. There has been an increasing interest in computational approaches that can predict gene expression directly from digitalized histopathology images. While image foundation models have shown promise in a variety of pathology downstream analysis, their performances on gene-expression prediction are still limited. Explicitly incorporating information from the transcriptomic models can help image models to address domain shift, yet the fine-tuning and alignment of foundation models can be expensive. In the work, we propose Parameter Efficient Knowledge trAnsfer (PEKA), a novel framework that leverages Block-Affine Adaptation and integrates knowledge distillation and structure alignment losses for cross-modal knowledge transfer. We evaluated PEKA for gene expression prediction using multiple spatial transcriptomics datasets (comprising 206,123 image tiles with matched gene expression profiles) that encompassed various types of tissue. PEKA achieved at least 5\% performance improvement over baseline foundation models while also outperforming alternative parameter-efficient fine-tuning strategies. We will release the code, datasets and aligned models after peer-review to facilitate broader adoption and further development for parameter efficient model alignment.

Upcycling Noise for Federated Unlearning

In Federated Learning (FL), multiple clients collaboratively train a model without sharing raw data. This paradigm can be further enhanced by Differential Privacy (DP) to protect local data from information inference attacks and is thus termed DPFL. An emerging privacy requirement, ``the right to be forgotten'' for clients, poses new challenges to DPFL but remains largely unexplored. Despite numerous studies on federated unlearning (FU), they are inapplicable to DPFL because the noise introduced by the DP mechanism compromises their effectiveness and efficiency. In this paper, we propose Federated Unlearning with Indistinguishability (FUI) to unlearn the local data of a target client in DPFL for the first time. FUI consists of two main steps: local model retraction and global noise calibration, resulting in an unlearning model that is statistically indistinguishable from the retrained model. Specifically, we demonstrate that the noise added in DPFL can endow the unlearning model with a certain level of indistinguishability after local model retraction, and then fortify the degree of unlearning through global noise calibration. Additionally, for the efficient and consistent implementation of the proposed FUI, we formulate a two-stage Stackelberg game to derive optimal unlearning strategies for both the server and the target client. Privacy and convergence analyses confirm theoretical guarantees, while experimental results based on four real-world datasets illustrate that our proposed FUI achieves superior model performance and higher efficiency compared to mainstream FU schemes. Simulation results further verify the optimality of the derived unlearning strategies.

A Unified Platform for At-Home Post-Stroke Rehabilitation Enabled by Wearable Technologies and Artificial Intelligence

At-home rehabilitation for post-stroke patients presents significant challenges, as continuous, personalized care is often limited outside clinical settings. Additionally, the absence of comprehensive solutions addressing diverse rehabilitation needs in home environments complicates recovery efforts. Here, we introduce a smart home platform that integrates wearable sensors, ambient monitoring, and large language model (LLM)-powered assistance to provide seamless health monitoring and intelligent support. The system leverages machine learning enabled plantar pressure arrays for motor recovery assessment (94% classification accuracy), a wearable eye-tracking module for cognitive evaluation, and ambient sensors for precise smart home control (100% operational success, <1 s latency). Additionally, the LLM-powered agent, Auto-Care, offers real-time interventions, such as health reminders and environmental adjustments, enhancing user satisfaction by 29%. This work establishes a fully integrated platform for long-term, personalized rehabilitation, offering new possibilities for managing chronic conditions and supporting aging populations.

Airport Delay Prediction with Temporal Fusion Transformers

Since flight delay hurts passengers, airlines, and airports, its prediction becomes crucial for the decision-making of all stakeholders in the aviation industry and thus has been attempted by various previous research. However, previous delay predictions are often categorical and at a highly aggregated level. To improve that, this study proposes to apply the novel Temporal Fusion Transformer model and predict numerical airport arrival delays at quarter hour level for U.S. top 30 airports. Inputs to our model include airport demand and capacity forecasts, historic airport operation efficiency information, airport wind and visibility conditions, as well as enroute weather and traffic conditions. The results show that our model achieves satisfactory performance measured by small prediction errors on the test set. In addition, the interpretability analysis of the model outputs identifies the important input factors for delay prediction.

Cross-Validation Is All You Need: A Statistical Approach To Label Noise Estimation

Label noise is prevalent in machine learning datasets. It is crucial to identify and remove label noise because models trained on noisy data can have substantially reduced accuracy and generalizability. Most existing label noise detection approaches are designed for classification tasks, and data cleaning for outcome prediction analysis is relatively unexplored. Inspired by the fluctuations in performance across different folds in cross-validation, we propose Repeated Cross-Validations for label noise estimation (ReCoV) to address this gap. ReCoV constructs a noise histogram that ranks the noise level of samples based on a large number of cross-validations by recording sample IDs in each worst-performing fold. We further propose three approaches for identifying noisy samples based on noise histograms to address increasingly complex noise distributions. We show that ReCoV outperforms state-of-the-art algorithms for label cleaning in a classification task benchmark. More importantly, we show that removing ReCoV-identified noisy samples in two medical imaging outcome prediction datasets significantly improves model performance on test sets. As a statistical approach that does not rely on hyperparameters, noise distributions, or model structures, ReCoV is compatible with any machine learning analysis.

Intra-Modal Constraint Loss For Image-Text Retrieval

Cross-modal retrieval has drawn much attention in both computer vision and natural language processing domains. With the development of convolutional and recurrent neural networks, the bottleneck of retrieval across image-text modalities is no longer the extraction of image and text features but an efficient loss function learning in embedding space. Many loss functions try to closer pairwise features from heterogeneous modalities. This paper proposes a method for learning joint embedding of images and texts using an intra-modal constraint loss function to reduce the violation of negative pairs from the same homogeneous modality. Experimental results show that our approach outperforms state-of-the-art bi-directional image-text retrieval methods on Flickr30K and Microsoft COCO datasets. Our code is publicly available: https://github.com/CanonChen/IMC.

Metastatic Cancer Outcome Prediction with Injective Multiple Instance Pooling

Cancer stage is a large determinant of patient prognosis and management in many cancer types, and is often assessed using medical imaging modalities, such as CT and MRI. These medical images contain rich information that can be explored to stratify patients within each stage group to further improve prognostic algorithms. Although the majority of cancer deaths result from metastatic and multifocal disease, building imaging biomarkers for patients with multiple tumors has been a challenging task due to the lack of annotated datasets and standard study framework. In this paper, we process two public datasets to set up a benchmark cohort of 341 patient in total for studying outcome prediction of multifocal metastatic cancer. We identify the lack of expressiveness in common multiple instance classification networks and propose two injective multiple instance pooling functions that are better suited to outcome prediction. Our results show that multiple instance learning with injective pooling functions can achieve state-of-the-art performance in the non-small-cell lung cancer CT and head and neck CT outcome prediction benchmarking tasks. We will release the processed multifocal datasets, our code and the intermediate files i.e. extracted radiomic features to support further transparent and reproducible research.