A Study on Context Length and Efficient Transformers for Biomedical Image Analysis

Biomedical imaging modalities often produce high-resolution, multi-dimensional images that pose computational challenges for deep neural networks. These computational challenges are compounded when training transformers due to the self-attention operator, which scales quadratically with context length. Recent developments in long-context models have potential to alleviate these difficulties and enable more efficient application of transformers to large biomedical images, although a systematic evaluation on this topic is lacking. In this study, we investigate the impact of context length on biomedical image analysis and we evaluate the performance of recently proposed long-context models. We first curate a suite of biomedical imaging datasets, including 2D and 3D data for segmentation, denoising, and classification tasks. We then analyze the impact of context length on network performance using the Vision Transformer and Swin Transformer by varying patch size and attention window size. Our findings reveal a strong relationship between context length and performance, particularly for pixel-level prediction tasks. Finally, we show that recent long-context models demonstrate significant improvements in efficiency while maintaining comparable performance, though we highlight where gaps remain. This work underscores the potential and challenges of using long-context models in biomedical imaging.

On Distilling the Displacement Knowledge for Few-Shot Class-Incremental Learning

Few-shot Class-Incremental Learning (FSCIL) addresses the challenges of evolving data distributions and the difficulty of data acquisition in real-world scenarios. To counteract the catastrophic forgetting typically encountered in FSCIL, knowledge distillation is employed as a way to maintain the knowledge from learned data distribution. Recognizing the limitations of generating discriminative feature representations in a few-shot context, our approach incorporates structural information between samples into knowledge distillation. This structural information serves as a remedy for the low quality of features. Diverging from traditional structured distillation methods that compute sample similarity, we introduce the Displacement Knowledge Distillation (DKD) method. DKD utilizes displacement rather than similarity between samples, incorporating both distance and angular information to significantly enhance the information density retained through knowledge distillation. Observing performance disparities in feature distribution between base and novel classes, we propose the Dual Distillation Network (DDNet). This network applies traditional knowledge distillation to base classes and DKD to novel classes, challenging the conventional integration of novel classes with base classes. Additionally, we implement an instance-aware sample selector during inference to dynamically adjust dual branch weights, thereby leveraging the complementary strengths of each approach. Extensive testing on three benchmarks demonstrates that DDNet achieves state-of-the-art results. Moreover, through rigorous experimentation and comparison, we establish the robustness and general applicability of our proposed DKD method.

PEARL: Input-Agnostic Prompt Enhancement with Negative Feedback Regulation for Class-Incremental Learning

Class-incremental learning (CIL) aims to continuously introduce novel categories into a classification system without forgetting previously learned ones, thus adapting to evolving data distributions. Researchers are currently focusing on leveraging the rich semantic information of pre-trained models (PTMs) in CIL tasks. Prompt learning has been adopted in CIL for its ability to adjust data distribution to better align with pre-trained knowledge. This paper critically examines the limitations of existing methods from the perspective of prompt learning, which heavily rely on input information. To address this issue, we propose a novel PTM-based CIL method called Input-Agnostic Prompt Enhancement with Negative Feedback Regulation (PEARL). In PEARL, we implement an input-agnostic global prompt coupled with an adaptive momentum update strategy to reduce the model's dependency on data distribution, thereby effectively mitigating catastrophic forgetting. Guided by negative feedback regulation, this adaptive momentum update addresses the parameter sensitivity inherent in fixed-weight momentum updates. Furthermore, it fosters the continuous enhancement of the prompt for new tasks by harnessing correlations between different tasks in CIL. Experiments on six benchmarks demonstrate that our method achieves state-of-the-art performance. The code is available at: https://github.com/qinyongchun/PEARL.

SVasP: Self-Versatility Adversarial Style Perturbation for Cross-Domain Few-Shot Learning

Cross-Domain Few-Shot Learning (CD-FSL) aims to transfer knowledge from seen source domains to unseen target domains, which is crucial for evaluating the generalization and robustness of models. Recent studies focus on utilizing visual styles to bridge the domain gap between different domains. However, the serious dilemma of gradient instability and local optimization problem occurs in those style-based CD-FSL methods. This paper addresses these issues and proposes a novel crop-global style perturbation method, called \underline{\textbf{S}}elf-\underline{\textbf{V}}ersatility \underline{\textbf{A}}dversarial \underline{\textbf{S}}tyle \underline{\textbf{P}}erturbation (\textbf{SVasP}), which enhances the gradient stability and escapes from poor sharp minima jointly. Specifically, SVasP simulates more diverse potential target domain adversarial styles via diversifying input patterns and aggregating localized crop style gradients, to serve as global style perturbation stabilizers within one image, a concept we refer to as self-versatility. Then a novel objective function is proposed to maximize visual discrepancy while maintaining semantic consistency between global, crop, and adversarial features. Having the stabilized global style perturbation in the training phase, one can obtain a flattened minima in the loss landscape, boosting the transferability of the model to the target domains. Extensive experiments on multiple benchmark datasets demonstrate that our method significantly outperforms existing state-of-the-art methods. Our codes are available at https://github.com/liwenqianSEU/SVasP.

MRJ-Agent: An Effective Jailbreak Agent for Multi-Round Dialogue

Large Language Models (LLMs) demonstrate outstanding performance in their reservoir of knowledge and understanding capabilities, but they have also been shown to be prone to illegal or unethical reactions when subjected to jailbreak attacks. To ensure their responsible deployment in critical applications, it is crucial to understand the safety capabilities and vulnerabilities of LLMs. Previous works mainly focus on jailbreak in single-round dialogue, overlooking the potential jailbreak risks in multi-round dialogues, which are a vital way humans interact with and extract information from LLMs. Some studies have increasingly concentrated on the risks associated with jailbreak in multi-round dialogues. These efforts typically involve the use of manually crafted templates or prompt engineering techniques. However, due to the inherent complexity of multi-round dialogues, their jailbreak performance is limited. To solve this problem, we propose a novel multi-round dialogue jailbreaking agent, emphasizing the importance of stealthiness in identifying and mitigating potential threats to human values posed by LLMs. We propose a risk decomposition strategy that distributes risks across multiple rounds of queries and utilizes psychological strategies to enhance attack strength. Extensive experiments show that our proposed method surpasses other attack methods and achieves state-of-the-art attack success rate. We will make the corresponding code and dataset available for future research. The code will be released soon.

Cross-Organ Domain Adaptive Neural Network for Pancreatic Endoscopic Ultrasound Image Segmentation

Accurate segmentation of lesions in pancreatic endoscopic ultrasound (EUS) images is crucial for effective diagnosis and treatment. However, the collection of enough crisp EUS images for effective diagnosis is arduous. Recently, domain adaptation (DA) has been employed to address these challenges by leveraging related knowledge from other domains. Most DA methods only focus on multi-view representations of the same organ, which makes it still tough to clearly depict the tumor lesion area with limited semantic information. Although transferring homogeneous similarity from different organs could benefit the issue, there is a lack of relevant work due to the enormous domain gap between them. To address these challenges, we propose the Cross-Organ Tumor Segmentation Networks (COTS-Nets), consisting of a universal network and an auxiliary network. The universal network utilizes boundary loss to learn common boundary information of different tumors, enabling accurate delineation of tumors in EUS despite limited and low-quality data. Simultaneously, we incorporate consistency loss in the universal network to align the prediction of pancreatic EUS with tumor boundaries from other organs to mitigate the domain gap. To further reduce the cross-organ domain gap, the auxiliary network integrates multi-scale features from different organs, aiding the universal network in acquiring domain-invariant knowledge. Systematic experiments demonstrate that COTS-Nets significantly improves the accuracy of pancreatic cancer diagnosis. Additionally, we developed the Pancreatic Cancer Endoscopic Ultrasound (PCEUS) dataset, comprising 501 pathologically confirmed pancreatic EUS images, to facilitate model development.

Towards Rehearsal-Free Multilingual ASR: A LoRA-based Case Study on Whisper

Pre-trained multilingual speech foundation models, like Whisper, have shown impressive performance across different languages. However, adapting these models to new or specific languages is computationally extensive and faces catastrophic forgetting problems. Addressing these issues, our study investigates strategies to enhance the model on new languages in the absence of original training data, while also preserving the established performance on the original languages. Specifically, we first compare various LoRA-based methods to find out their vulnerability to forgetting. To mitigate this issue, we propose to leverage the LoRA parameters from the original model for approximate orthogonal gradient descent on the new samples. Additionally, we also introduce a learnable rank coefficient to allocate trainable parameters for more efficient training. Our experiments with a Chinese Whisper model (for Uyghur and Tibetan) yield better results with a more compact parameter set.

Towards Few-Shot Learning in the Open World: A Review and Beyond

Human intelligence is characterized by our ability to absorb and apply knowledge from the world around us, especially in rapidly acquiring new concepts from minimal examples, underpinned by prior knowledge. Few-shot learning (FSL) aims to mimic this capacity by enabling significant generalizations and transferability. However, traditional FSL frameworks often rely on assumptions of clean, complete, and static data, conditions that are seldom met in real-world environments. Such assumptions falter in the inherently uncertain, incomplete, and dynamic contexts of the open world. This paper presents a comprehensive review of recent advancements designed to adapt FSL for use in open-world settings. We categorize existing methods into three distinct types of open-world few-shot learning: those involving varying instances, varying classes, and varying distributions. Each category is discussed in terms of its specific challenges and methods, as well as its strengths and weaknesses. We standardize experimental settings and metric benchmarks across scenarios, and provide a comparative analysis of the performance of various methods. In conclusion, we outline potential future research directions for this evolving field. It is our hope that this review will catalyze further development of effective solutions to these complex challenges, thereby advancing the field of artificial intelligence.

fairBERTs: Erasing Sensitive Information Through Semantic and Fairness-aware Perturbations

Pre-trained language models (PLMs) have revolutionized both the natural language processing research and applications. However, stereotypical biases (e.g., gender and racial discrimination) encoded in PLMs have raised negative ethical implications for PLMs, which critically limits their broader applications. To address the aforementioned unfairness issues, we present fairBERTs, a general framework for learning fair fine-tuned BERT series models by erasing the protected sensitive information via semantic and fairness-aware perturbations generated by a generative adversarial network. Through extensive qualitative and quantitative experiments on two real-world tasks, we demonstrate the great superiority of fairBERTs in mitigating unfairness while maintaining the model utility. We also verify the feasibility of transferring adversarial components in fairBERTs to other conventionally trained BERT-like models for yielding fairness improvements. Our findings may shed light on further research on building fairer fine-tuned PLMs.

UniPSDA: Unsupervised Pseudo Semantic Data Augmentation for Zero-Shot Cross-Lingual Natural Language Understanding

Cross-lingual representation learning transfers knowledge from resource-rich data to resource-scarce ones to improve the semantic understanding abilities of different languages. However, previous works rely on shallow unsupervised data generated by token surface matching, regardless of the global context-aware semantics of the surrounding text tokens. In this paper, we propose an Unsupervised Pseudo Semantic Data Augmentation (UniPSDA) mechanism for cross-lingual natural language understanding to enrich the training data without human interventions. Specifically, to retrieve the tokens with similar meanings for the semantic data augmentation across different languages, we propose a sequential clustering process in 3 stages: within a single language, across multiple languages of a language family, and across languages from multiple language families. Meanwhile, considering the multi-lingual knowledge infusion with context-aware semantics while alleviating computation burden, we directly replace the key constituents of the sentences with the above-learned multi-lingual family knowledge, viewed as pseudo-semantic. The infusion process is further optimized via three de-biasing techniques without introducing any neural parameters. Extensive experiments demonstrate that our model consistently improves the performance on general zero-shot cross-lingual natural language understanding tasks, including sequence classification, information extraction, and question answering.