Citrus: Leveraging Expert Cognitive Pathways in a Medical Language Model for Advanced Medical Decision Support

Large language models (LLMs), particularly those with reasoning capabilities, have rapidly advanced in recent years, demonstrating significant potential across a wide range of applications. However, their deployment in healthcare, especially in disease reasoning tasks, is hindered by the challenge of acquiring expert-level cognitive data. In this paper, we introduce Citrus, a medical language model that bridges the gap between clinical expertise and AI reasoning by emulating the cognitive processes of medical experts. The model is trained on a large corpus of simulated expert disease reasoning data, synthesized using a novel approach that accurately captures the decision-making pathways of clinicians. This approach enables Citrus to better simulate the complex reasoning processes involved in diagnosing and treating medical conditions. To further address the lack of publicly available datasets for medical reasoning tasks, we release the last-stage training data, including a custom-built medical diagnostic dialogue dataset. This open-source contribution aims to support further research and development in the field. Evaluations using authoritative benchmarks such as MedQA, covering tasks in medical reasoning and language understanding, show that Citrus achieves superior performance compared to other models of similar size. These results highlight Citrus potential to significantly enhance medical decision support systems, providing a more accurate and efficient tool for clinical decision-making.

JoyVASA: Portrait and Animal Image Animation with Diffusion-Based Audio-Driven Facial Dynamics and Head Motion Generation

Audio-driven portrait animation has made significant advances with diffusion-based models, improving video quality and lipsync accuracy. However, the increasing complexity of these models has led to inefficiencies in training and inference, as well as constraints on video length and inter-frame continuity. In this paper, we propose JoyVASA, a diffusion-based method for generating facial dynamics and head motion in audio-driven facial animation. Specifically, in the first stage, we introduce a decoupled facial representation framework that separates dynamic facial expressions from static 3D facial representations. This decoupling allows the system to generate longer videos by combining any static 3D facial representation with dynamic motion sequences. Then, in the second stage, a diffusion transformer is trained to generate motion sequences directly from audio cues, independent of character identity. Finally, a generator trained in the first stage uses the 3D facial representation and the generated motion sequences as inputs to render high-quality animations. With the decoupled facial representation and the identity-independent motion generation process, JoyVASA extends beyond human portraits to animate animal faces seamlessly. The model is trained on a hybrid dataset of private Chinese and public English data, enabling multilingual support. Experimental results validate the effectiveness of our approach. Future work will focus on improving real-time performance and refining expression control, further expanding the applications in portrait animation. The code will be available at: https://jdhalgo.github.io/JoyVASA.

JoyType: A Robust Design for Multilingual Visual Text Creation

Generating images with accurately represented text, especially in non-Latin languages, poses a significant challenge for diffusion models. Existing approaches, such as the integration of hint condition diagrams via auxiliary networks (e.g., ControlNet), have made strides towards addressing this issue. However, diffusion models often fall short in tasks requiring controlled text generation, such as specifying particular fonts or producing text in small fonts. In this paper, we introduce a novel approach for multilingual visual text creation, named JoyType, designed to maintain the font style of text during the image generation process. Our methodology begins with assembling a training dataset, JoyType-1M, comprising 1 million pairs of data. Each pair includes an image, its description, and glyph instructions corresponding to the font style within the image. We then developed a text control network, Font ControlNet, tasked with extracting font style information to steer the image generation. To further enhance our model's ability to maintain font style, notably in generating small-font text, we incorporated a multi-layer OCR-aware loss into the diffusion process. This enhancement allows JoyType to direct text rendering using low-level descriptors. Our evaluations, based on both visual and accuracy metrics, demonstrate that JoyType significantly outperforms existing state-of-the-art methods. Additionally, JoyType can function as a plugin, facilitating the creation of varied image styles in conjunction with other stable diffusion models on HuggingFace and CivitAI. Our project is open-sourced on https://jdh-algo.github.io/JoyType/.

MHAD: Multimodal Home Activity Dataset with Multi-Angle Videos and Synchronized Physiological Signals

Video-based physiology, exemplified by remote photoplethysmography (rPPG), extracts physiological signals such as pulse and respiration by analyzing subtle changes in video recordings. This non-contact, real-time monitoring method holds great potential for home settings. Despite the valuable contributions of public benchmark datasets to this technology, there is currently no dataset specifically designed for passive home monitoring. Existing datasets are often limited to close-up, static, frontal recordings and typically include only 1-2 physiological signals. To advance video-based physiology in real home settings, we introduce the MHAD dataset. It comprises 1,440 videos from 40 subjects, capturing 6 typical activities from 3 angles in a real home environment. Additionally, 5 physiological signals were recorded, making it a comprehensive video-based physiology dataset. MHAD is compatible with the rPPG-toolbox and has been validated using several unsupervised and supervised methods. Our dataset is publicly available at https://github.com/jdh-algo/MHAD-Dataset.

ECG Biometric Authentication Using Self-Supervised Learning for IoT Edge Sensors

Wearable Internet of Things (IoT) devices are gaining ground for continuous physiological data acquisition and health monitoring. These physiological signals can be used for security applications to achieve continuous authentication and user convenience due to passive data acquisition. This paper investigates an electrocardiogram (ECG) based biometric user authentication system using features derived from the Convolutional Neural Network (CNN) and self-supervised contrastive learning. Contrastive learning enables us to use large unlabeled datasets to train the model and establish its generalizability. We propose approaches enabling the CNN encoder to extract appropriate features that distinguish the user from other subjects. When evaluated using the PTB ECG database with 290 subjects, the proposed technique achieved an authentication accuracy of 99.15%. To test its generalizability, we applied the model to two new datasets, the MIT-BIH Arrhythmia Database and the ECG-ID Database, achieving over 98.5% accuracy without any modifications. Furthermore, we show that repeating the authentication step three times can increase accuracy to nearly 100% for both PTBDB and ECGIDDB. This paper also presents model optimizations for embedded device deployment, which makes the system more relevant to real-world scenarios. To deploy our model in IoT edge sensors, we optimized the model complexity by applying quantization and pruning. The optimized model achieves 98.67% accuracy on PTBDB, with 0.48% accuracy loss and 62.6% CPU cycles compared to the unoptimized model. An accuracy-vs-time-complexity tradeoff analysis is performed, and results are presented for different optimization levels.

3SHNet: Boosting Image-Sentence Retrieval via Visual Semantic-Spatial Self-Highlighting

In this paper, we propose a novel visual Semantic-Spatial Self-Highlighting Network (termed 3SHNet) for high-precision, high-efficiency and high-generalization image-sentence retrieval. 3SHNet highlights the salient identification of prominent objects and their spatial locations within the visual modality, thus allowing the integration of visual semantics-spatial interactions and maintaining independence between two modalities. This integration effectively combines object regions with the corresponding semantic and position layouts derived from segmentation to enhance the visual representation. And the modality-independence guarantees efficiency and generalization. Additionally, 3SHNet utilizes the structured contextual visual scene information from segmentation to conduct the local (region-based) or global (grid-based) guidance and achieve accurate hybrid-level retrieval. Extensive experiments conducted on MS-COCO and Flickr30K benchmarks substantiate the superior performances, inference efficiency and generalization of the proposed 3SHNet when juxtaposed with contemporary state-of-the-art methodologies. Specifically, on the larger MS-COCO 5K test set, we achieve 16.3%, 24.8%, and 18.3% improvements in terms of rSum score, respectively, compared with the state-of-the-art methods using different image representations, while maintaining optimal retrieval efficiency. Moreover, our performance on cross-dataset generalization improves by 18.6%. Data and code are available at https://github.com/XuriGe1995/3SHNet.

PYRA: Parallel Yielding Re-Activation for Training-Inference Efficient Task Adaptation

Recently, the scale of transformers has grown rapidly, which introduces considerable challenges in terms of training overhead and inference efficiency in the scope of task adaptation. Existing works, namely Parameter-Efficient Fine-Tuning (PEFT) and model compression, have separately investigated the challenges. However, PEFT cannot guarantee the inference efficiency of the original backbone, especially for large-scale models. Model compression requires significant training costs for structure searching and re-training. Consequently, a simple combination of them cannot guarantee accomplishing both training efficiency and inference efficiency with minimal costs. In this paper, we propose a novel Parallel Yielding Re-Activation (PYRA) method for such a challenge of training-inference efficient task adaptation. PYRA first utilizes parallel yielding adaptive weights to comprehensively perceive the data distribution in downstream tasks. A re-activation strategy for token modulation is then applied for tokens to be merged, leading to calibrated token features. Extensive experiments demonstrate that PYRA outperforms all competing methods under both low compression rate and high compression rate, demonstrating its effectiveness and superiority in maintaining both training efficiency and inference efficiency for large-scale foundation models. Our code will be released to the public.

A Bi-Pyramid Multimodal Fusion Method for the Diagnosis of Bipolar Disorders

Previous research on the diagnosis of Bipolar disorder has mainly focused on resting-state functional magnetic resonance imaging. However, their accuracy can not meet the requirements of clinical diagnosis. Efficient multimodal fusion strategies have great potential for applications in multimodal data and can further improve the performance of medical diagnosis models. In this work, we utilize both sMRI and fMRI data and propose a novel multimodal diagnosis model for bipolar disorder. The proposed Patch Pyramid Feature Extraction Module extracts sMRI features, and the spatio-temporal pyramid structure extracts the fMRI features. Finally, they are fused by a fusion module to output diagnosis results with a classifier. Extensive experiments show that our proposed method outperforms others in balanced accuracy from 0.657 to 0.732 on the OpenfMRI dataset, and achieves the state of the art.

Unsupervised Pre-Training Using Masked Autoencoders for ECG Analysis

Unsupervised learning methods have become increasingly important in deep learning due to their demonstrated large utilization of datasets and higher accuracy in computer vision and natural language processing tasks. There is a growing trend to extend unsupervised learning methods to other domains, which helps to utilize a large amount of unlabelled data. This paper proposes an unsupervised pre-training technique based on masked autoencoder (MAE) for electrocardiogram (ECG) signals. In addition, we propose a task-specific fine-tuning to form a complete framework for ECG analysis. The framework is high-level, universal, and not individually adapted to specific model architectures or tasks. Experiments are conducted using various model architectures and large-scale datasets, resulting in an accuracy of 94.39% on the MITDB dataset for ECG arrhythmia classification task. The result shows a better performance for the classification of previously unseen data for the proposed approach compared to fully supervised methods.

Multi-Dimension-Embedding-Aware Modality Fusion Transformer for Psychiatric Disorder Clasification

Deep learning approaches, together with neuroimaging techniques, play an important role in psychiatric disorders classification. Previous studies on psychiatric disorders diagnosis mainly focus on using functional connectivity matrices of resting-state functional magnetic resonance imaging (rs-fMRI) as input, which still needs to fully utilize the rich temporal information of the time series of rs-fMRI data. In this work, we proposed a multi-dimension-embedding-aware modality fusion transformer (MFFormer) for schizophrenia and bipolar disorder classification using rs-fMRI and T1 weighted structural MRI (T1w sMRI). Concretely, to fully utilize the temporal information of rs-fMRI and spatial information of sMRI, we constructed a deep learning architecture that takes as input 2D time series of rs-fMRI and 3D volumes T1w. Furthermore, to promote intra-modality attention and information fusion across different modalities, a fusion transformer module (FTM) is designed through extensive self-attention of hybrid feature maps of multi-modality. In addition, a dimension-up and dimension-down strategy is suggested to properly align feature maps of multi-dimensional from different modalities. Experimental results on our private and public OpenfMRI datasets show that our proposed MFFormer performs better than that using a single modality or multi-modality MRI on schizophrenia and bipolar disorder diagnosis.