Detailed retinal vessel segmentation without human annotations using simulated optical coherence tomography angiographs

Optical coherence tomography angiography (OCTA) is a non-invasive imaging modality that can acquire high-resolution volumes of the retinal vasculature and aid the diagnosis of ocular, neurological and cardiac diseases. Segmentation of the visible blood vessels is a common first step when extracting quantitative biomarkers from these images. Classical segmentation algorithms based on thresholding are strongly affected by image artifacts and limited signal-to-noise ratio. The use of modern, deep learning-based segmentation methods has been inhibited by a lack of large datasets with detailed annotations of the blood vessels. To address this issue, recent work has employed transfer learning, where a segmentation network is trained on synthetic OCTA images and is then applied to real data. However, the previously proposed simulation models are incapable of faithfully modeling the retinal vasculature and do not provide effective domain adaptation. Because of this, current methods are not able to fully segment the retinal vasculature, in particular the smallest capillaries. In this work, we present a lightweight simulation of the retinal vascular network based on space colonization for faster and more realistic OCTA synthesis. Moreover, we introduce three contrast adaptation pipelines to decrease the domain gap between real and artificial images. We demonstrate the superior performance of our approach in extensive quantitative and qualitative experiments on three public datasets that compare our method to traditional computer vision algorithms and supervised training using human annotations. Finally, we make our entire pipeline publicly available, including the source code, pretrained models, and a large dataset of synthetic OCTA images.

MIR-GAN: Refining Frame-Level Modality-Invariant Representations with Adversarial Network for Audio-Visual Speech Recognition

Audio-visual speech recognition (AVSR) attracts a surge of research interest recently by leveraging multimodal signals to understand human speech. Mainstream approaches addressing this task have developed sophisticated architectures and techniques for multi-modality fusion and representation learning. However, the natural heterogeneity of different modalities causes distribution gap between their representations, making it challenging to fuse them. In this paper, we aim to learn the shared representations across modalities to bridge their gap. Different from existing similar methods on other multimodal tasks like sentiment analysis, we focus on the temporal contextual dependencies considering the sequence-to-sequence task setting of AVSR. In particular, we propose an adversarial network to refine frame-level modality-invariant representations (MIR-GAN), which captures the commonality across modalities to ease the subsequent multimodal fusion process. Extensive experiments on public benchmarks LRS3 and LRS2 show that our approach outperforms the state-of-the-arts.

Hearing Lips in Noise: Universal Viseme-Phoneme Mapping and Transfer for Robust Audio-Visual Speech Recognition

Audio-visual speech recognition (AVSR) provides a promising solution to ameliorate the noise-robustness of audio-only speech recognition with visual information. However, most existing efforts still focus on audio modality to improve robustness considering its dominance in AVSR task, with noise adaptation techniques such as front-end denoise processing. Though effective, these methods are usually faced with two practical challenges: 1) lack of sufficient labeled noisy audio-visual training data in some real-world scenarios and 2) less optimal model generality to unseen testing noises. In this work, we investigate the noise-invariant visual modality to strengthen robustness of AVSR, which can adapt to any testing noises while without dependence on noisy training data, a.k.a., unsupervised noise adaptation. Inspired by human perception mechanism, we propose a universal viseme-phoneme mapping (UniVPM) approach to implement modality transfer, which can restore clean audio from visual signals to enable speech recognition under any noisy conditions. Extensive experiments on public benchmarks LRS3 and LRS2 show that our approach achieves the state-of-the-art under various noisy as well as clean conditions. In addition, we also outperform previous state-of-the-arts on visual speech recognition task.

Federated Few-shot Learning

Federated Learning (FL) enables multiple clients to collaboratively learn a machine learning model without exchanging their own local data. In this way, the server can exploit the computational power of all clients and train the model on a larger set of data samples among all clients. Although such a mechanism is proven to be effective in various fields, existing works generally assume that each client preserves sufficient data for training. In practice, however, certain clients may only contain a limited number of samples (i.e., few-shot samples). For example, the available photo data taken by a specific user with a new mobile device is relatively rare. In this scenario, existing FL efforts typically encounter a significant performance drop on these clients. Therefore, it is urgent to develop a few-shot model that can generalize to clients with limited data under the FL scenario. In this paper, we refer to this novel problem as \emph{federated few-shot learning}. Nevertheless, the problem remains challenging due to two major reasons: the global data variance among clients (i.e., the difference in data distributions among clients) and the local data insufficiency in each client (i.e., the lack of adequate local data for training). To overcome these two challenges, we propose a novel federated few-shot learning framework with two separately updated models and dedicated training strategies to reduce the adverse impact of global data variance and local data insufficiency. Extensive experiments on four prevalent datasets that cover news articles and images validate the effectiveness of our framework compared with the state-of-the-art baselines. Our code is provided\footnote{\href{https://github.com/SongW-SW/F2L}{https://github.com/SongW-SW/F2L}}.

Hierarchical Task Network Planning for Facilitating Cooperative Multi-Agent Reinforcement Learning

Exploring sparse reward multi-agent reinforcement learning (MARL) environments with traps in a collaborative manner is a complex task. Agents typically fail to reach the goal state and fall into traps, which affects the overall performance of the system. To overcome this issue, we present SOMARL, a framework that uses prior knowledge to reduce the exploration space and assist learning. In SOMARL, agents are treated as part of the MARL environment, and symbolic knowledge is embedded using a tree structure to build a knowledge hierarchy. The framework has a two-layer hierarchical structure, comprising a hybrid module with a Hierarchical Task Network (HTN) planning and meta-controller at the higher level, and a MARL-based interactive module at the lower level. The HTN module and meta-controller use Hierarchical Domain Definition Language (HDDL) and the option framework to formalize symbolic knowledge and obtain domain knowledge and a symbolic option set, respectively. Moreover, the HTN module leverages domain knowledge to guide low-level agent exploration by assisting the meta-controller in selecting symbolic options. The meta-controller further computes intrinsic rewards of symbolic options to limit exploration behavior and adjust HTN planning solutions as needed. We evaluate SOMARL on two benchmarks, FindTreasure and MoveBox, and report superior performance over state-of-the-art MARL and subgoal-based baselines for MARL environments significantly.

Unifying Large Language Models and Knowledge Graphs: A Roadmap

Large language models (LLMs), such as ChatGPT and GPT4, are making new waves in the field of natural language processing and artificial intelligence, due to their emergent ability and generalizability. However, LLMs are black-box models, which often fall short of capturing and accessing factual knowledge. In contrast, Knowledge Graphs (KGs), Wikipedia and Huapu for example, are structured knowledge models that explicitly store rich factual knowledge. KGs can enhance LLMs by providing external knowledge for inference and interpretability. Meanwhile, KGs are difficult to construct and evolving by nature, which challenges the existing methods in KGs to generate new facts and represent unseen knowledge. Therefore, it is complementary to unify LLMs and KGs together and simultaneously leverage their advantages. In this article, we present a forward-looking roadmap for the unification of LLMs and KGs. Our roadmap consists of three general frameworks, namely, 1) KG-enhanced LLMs, which incorporate KGs during the pre-training and inference phases of LLMs, or for the purpose of enhancing understanding of the knowledge learned by LLMs; 2) LLM-augmented KGs, that leverage LLMs for different KG tasks such as embedding, completion, construction, graph-to-text generation, and question answering; and 3) Synergized LLMs + KGs, in which LLMs and KGs play equal roles and work in a mutually beneficial way to enhance both LLMs and KGs for bidirectional reasoning driven by both data and knowledge. We review and summarize existing efforts within these three frameworks in our roadmap and pinpoint their future research directions.

MOFI: Learning Image Representations from Noisy Entity Annotated Images

We present MOFI, a new vision foundation model designed to learn image representations from noisy entity annotated images. MOFI differs from previous work in two key aspects: ($i$) pre-training data, and ($ii$) training recipe. Regarding data, we introduce a new approach to automatically assign entity labels to images from noisy image-text pairs. Our approach involves employing a named entity recognition model to extract entities from the alt-text, and then using a CLIP model to select the correct entities as labels of the paired image. The approach is simple, does not require costly human annotation, and can be readily scaled up to billions of image-text pairs mined from the web. Through this method, we have created Image-to-Entities (I2E), a new large-scale dataset with 1 billion images and 2 million distinct entities, covering rich visual concepts in the wild. Building upon the I2E dataset, we study different training recipes, including supervised pre-training, contrastive pre-training, and multi-task learning. For constrastive pre-training, we treat entity names as free-form text, and further enrich them with entity descriptions. Experiments show that supervised pre-training with large-scale fine-grained entity labels is highly effective for image retrieval tasks, and multi-task training further improves the performance. The final MOFI model achieves 86.66% mAP on the challenging GPR1200 dataset, surpassing the previous state-of-the-art performance of 72.19% from OpenAI's CLIP model. Further experiments on zero-shot and linear probe image classification also show that MOFI outperforms a CLIP model trained on the original image-text data, demonstrating the effectiveness of the I2E dataset in learning strong image representations.

Getting the Most from Eye-Tracking: User-Interaction Based Reading Region Estimation Dataset and Models

A single digital newsletter usually contains many messages (regions). Users' reading time spent on, and read level (skip/skim/read-in-detail) of each message is important for platforms to understand their users' interests, personalize their contents, and make recommendations. Based on accurate but expensive-to-collect eyetracker-recorded data, we built models that predict per-region reading time based on easy-to-collect Javascript browser tracking data. With eye-tracking, we collected 200k ground-truth datapoints on participants reading news on browsers. Then we trained machine learning and deep learning models to predict message-level reading time based on user interactions like mouse position, scrolling, and clicking. We reached 27\% percentage error in reading time estimation with a two-tower neural network based on user interactions only, against the eye-tracking ground truth data, while the heuristic baselines have around 46\% percentage error. We also discovered the benefits of replacing per-session models with per-timestamp models, and adding user pattern features. We concluded with suggestions on developing message-level reading estimation techniques based on available data.

Unsupervised Anomaly Detection in Medical Images Using Masked Diffusion Model

It can be challenging to identify brain MRI anomalies using supervised deep-learning techniques due to anatomical heterogeneity and the requirement for pixel-level labeling. Unsupervised anomaly detection approaches provide an alternative solution by relying only on sample-level labels of healthy brains to generate a desired representation to identify abnormalities at the pixel level. Although, generative models are crucial for generating such anatomically consistent representations of healthy brains, accurately generating the intricate anatomy of the human brain remains a challenge. In this study, we present a method called masked-DDPM (mDPPM), which introduces masking-based regularization to reframe the generation task of diffusion models. Specifically, we introduce Masked Image Modeling (MIM) and Masked Frequency Modeling (MFM) in our self-supervised approach that enables models to learn visual representations from unlabeled data. To the best of our knowledge, this is the first attempt to apply MFM in DPPM models for medical applications. We evaluate our approach on datasets containing tumors and numerous sclerosis lesions and exhibit the superior performance of our unsupervised method as compared to the existing fully/weakly supervised baselines. Code is available at https://github.com/hasan1292/mDDPM.

SAVE: Spectral-Shift-Aware Adaptation of Image Diffusion Models for Text-guided Video Editing

Text-to-Image (T2I) diffusion models have achieved remarkable success in synthesizing high-quality images conditioned on text prompts. Recent methods have tried to replicate the success by either training text-to-video (T2V) models on a very large number of text-video pairs or adapting T2I models on text-video pairs independently. Although the latter is computationally less expensive, it still takes a significant amount of time for per-video adaption. To address this issue, we propose SAVE, a novel spectral-shift-aware adaptation framework, in which we fine-tune the spectral shift of the parameter space instead of the parameters themselves. Specifically, we take the spectral decomposition of the pre-trained T2I weights and only control the change in the corresponding singular values, i.e. spectral shift, while freezing the corresponding singular vectors. To avoid drastic drift from the original T2I weights, we introduce a spectral shift regularizer that confines the spectral shift to be more restricted for large singular values and more relaxed for small singular values. Since we are only dealing with spectral shifts, the proposed method reduces the adaptation time significantly (approx. 10 times) and has fewer resource constrains for training. Such attributes posit SAVE to be more suitable for real-world applications, e.g. editing undesirable content during video streaming. We validate the effectiveness of SAVE with an extensive experimental evaluation under different settings, e.g. style transfer, object replacement, privacy preservation, etc.