Unpaired Image-to-Image Translation via a Self-Supervised Semantic Bridge

Adversarial diffusion and diffusion-inversion methods have advanced unpaired image-to-image translation, but each faces key limitations. Adversarial approaches require target-domain adversarial loss during training, which can limit generalization to unseen data, while diffusion-inversion methods often produce low-fidelity translations due to imperfect inversion into noise-latent representations. In this work, we propose the Self-Supervised Semantic Bridge (SSB), a versatile framework that integrates external semantic priors into diffusion bridge models to enable spatially faithful translation without cross-domain supervision. Our key idea is to leverage self-supervised visual encoders to learn representations that are invariant to appearance changes but capture geometric structure, forming a shared latent space that conditions the diffusion bridges. Extensive experiments show that SSB outperforms strong prior methods for challenging medical image synthesis in both in-domain and out-of-domain settings, and extends easily to high-quality text-guided editing.

IHF-Harmony: Multi-Modality Magnetic Resonance Images Harmonization using Invertible Hierarchy Flow Model

Retrospective MRI harmonization is limited by poor scalability across modalities and reliance on traveling subject datasets. To address these challenges, we introduce IHF-Harmony, a unified invertible hierarchy flow framework for multi-modality harmonization using unpaired data. By decomposing the translation process into reversible feature transformations, IHF-Harmony guarantees bijective mapping and lossless reconstruction to prevent anatomical distortion. Specifically, an invertible hierarchy flow (IHF) performs hierarchical subtractive coupling to progressively remove artefact-related features, while an artefact-aware normalization (AAN) employs anatomy-fixed feature modulation to accurately transfer target characteristics. Combined with anatomy and artefact consistency loss objectives, IHF-Harmony achieves high-fidelity harmonization that retains source anatomy. Experiments across multiple MRI modalities demonstrate that IHF-Harmony outperforms existing methods in both anatomical fidelity and downstream task performance, facilitating robust harmonization for large-scale multi-site imaging studies. Code will be released upon acceptance.

Bridging Day and Night: Target-Class Hallucination Suppression in Unpaired Image Translation

Day-to-night unpaired image translation is important to downstream tasks but remains challenging due to large appearance shifts and the lack of direct pixel-level supervision. Existing methods often introduce semantic hallucinations, where objects from target classes such as traffic signs and vehicles, as well as man-made light effects, are incorrectly synthesized. These hallucinations significantly degrade downstream performance. We propose a novel framework that detects and suppresses hallucinations of target-class features during unpaired translation. To detect hallucination, we design a dual-head discriminator that additionally performs semantic segmentation to identify hallucinated content in background regions. To suppress these hallucinations, we introduce class-specific prototypes, constructed by aggregating features of annotated target-domain objects, which act as semantic anchors for each class. Built upon a Schrodinger Bridge-based translation model, our framework performs iterative refinement, where detected hallucination features are explicitly pushed away from class prototypes in feature space, thus preserving object semantics across the translation trajectory.Experiments show that our method outperforms existing approaches both qualitatively and quantitatively. On the BDD100K dataset, it improves mAP by 15.5% for day-to-night domain adaptation, with a notable 31.7% gain for classes such as traffic lights that are prone to hallucinations.

MammoWise: Multi-Model Local RAG Pipeline for Mammography Report Generation

Screening mammography is high volume, time sensitive, and documentation heavy. Radiologists must translate subtle visual findings into consistent BI-RADS assessments, breast density categories, and structured narrative reports. While recent Vision Language Models (VLMs) enable image-to-text reporting, many rely on closed cloud systems or tightly coupled architectures that limit privacy, reproducibility, and adaptability. We present MammoWise, a local multi-model pipeline that transforms open source VLMs into mammogram report generators and multi-task classifiers. MammoWise supports any Ollama-hosted VLM and mammography dataset, and enables zero-shot, few-shot, and Chain-of-Thought prompting, with optional multimodal Retrieval Augmented Generation (RAG) using a vector database for case-specific context. We evaluate MedGemma, LLaVA-Med, and Qwen2.5-VL on VinDr-Mammo and DMID datasets, assessing report quality (BERTScore, ROUGE-L), BI-RADS classification, breast density, and key findings. Report generation is consistently strong and improves with few-shot prompting and RAG. Classification is feasible but sensitive to model and dataset choice. Parameter-efficient fine-tuning (QLoRA) of MedGemma improves reliability, achieving BI-RADS accuracy of 0.7545, density accuracy of 0.8840, and calcification accuracy of 0.9341 while preserving report quality. MammoWise provides a practical and extensible framework for deploying local VLMs for mammography reporting within a unified and reproducible workflow.

Can Agents Distinguish Visually Hard-to-Separate Diseases in a Zero-Shot Setting? A Pilot Study

The rapid progress of multimodal large language models (MLLMs) has led to increasing interest in agent-based systems. While most prior work in medical imaging concentrates on automating routine clinical workflows, we study an underexplored yet clinically significant setting: distinguishing visually hard-to-separate diseases in a zero-shot setting. We benchmark representative agents on two imaging-only proxy diagnostic tasks, (1) melanoma vs. atypical nevus and (2) pulmonary edema vs. pneumonia, where visual features are highly confounded despite substantial differences in clinical management. We introduce a multi-agent framework based on contrastive adjudication. Experimental results show improved diagnostic performance (an 11-percentage-point gain in accuracy on dermoscopy data) and reduced unsupported claims on qualitative samples, although overall performance remains insufficient for clinical deployment. We acknowledge the inherent uncertainty in human annotations and the absence of clinical context, which further limit the translation to real-world settings. Within this controlled setting, this pilot study provides preliminary insights into zero-shot agent performance in visually confounded scenarios.

XMorph: Explainable Brain Tumor Analysis Via LLM-Assisted Hybrid Deep Intelligence

Deep learning has significantly advanced automated brain tumor diagnosis, yet clinical adoption remains limited by interpretability and computational constraints. Conventional models often act as opaque ''black boxes'' and fail to quantify the complex, irregular tumor boundaries that characterize malignant growth. To address these challenges, we present XMorph, an explainable and computationally efficient framework for fine-grained classification of three prominent brain tumor types: glioma, meningioma, and pituitary tumors. We propose an Information-Weighted Boundary Normalization (IWBN) mechanism that emphasizes diagnostically relevant boundary regions alongside nonlinear chaotic and clinically validated features, enabling a richer morphological representation of tumor growth. A dual-channel explainable AI module combines GradCAM++ visual cues with LLM-generated textual rationales, translating model reasoning into clinically interpretable insights. The proposed framework achieves a classification accuracy of 96.0%, demonstrating that explainability and high performance can co-exist in AI-based medical imaging systems. The source code and materials for XMorph are all publicly available at: https://github.com/ALSER-Lab/XMorph.

Art2Mus: Artwork-to-Music Generation via Visual Conditioning and Large-Scale Cross-Modal Alignment

Music generation has advanced markedly through multimodal deep learning, enabling models to synthesize audio from text and, more recently, from images. However, existing image-conditioned systems suffer from two fundamental limitations: (i) they are typically trained on natural photographs, limiting their ability to capture the richer semantic, stylistic, and cultural content of artworks; and (ii) most rely on an image-to-text conversion stage, using language as a semantic shortcut that simplifies conditioning but prevents direct visual-to-audio learning. Motivated by these gaps, we introduce ArtSound, a large-scale multimodal dataset of 105,884 artwork-music pairs enriched with dual-modality captions, obtained by extending ArtGraph and the Free Music Archive. We further propose ArtToMus, the first framework explicitly designed for direct artwork-to-music generation, which maps digitized artworks to music without image-to-text translation or language-based semantic supervision. The framework projects visual embeddings into the conditioning space of a latent diffusion model, enabling music synthesis guided solely by visual information. Experimental results show that ArtToMus generates musically coherent and stylistically consistent outputs that reflect salient visual cues of the source artworks. While absolute alignment scores remain lower than those of text-conditioned systems-as expected given the substantially increased difficulty of removing linguistic supervision-ArtToMus achieves competitive perceptual quality and meaningful cross-modal correspondence. This work establishes direct visual-to-music generation as a distinct and challenging research direction, and provides resources that support applications in multimedia art, cultural heritage, and AI-assisted creative practice. Code and dataset will be publicly released upon acceptance.

BBQ-to-Image: Numeric Bounding Box and Qolor Control in Large-Scale Text-to-Image Models

Text-to-image models have rapidly advanced in realism and controllability, with recent approaches leveraging long, detailed captions to support fine-grained generation. However, a fundamental parametric gap remains: existing models rely on descriptive language, whereas professional workflows require precise numeric control over object location, size, and color. In this work, we introduce BBQ, a large-scale text-to-image model that directly conditions on numeric bounding boxes and RGB triplets within a unified structured-text framework. We obtain precise spatial and chromatic control by training on captions enriched with parametric annotations, without architectural modifications or inference-time optimization. This also enables intuitive user interfaces such as object dragging and color pickers, replacing ambiguous iterative prompting with precise, familiar controls. Across comprehensive evaluations, BBQ achieves strong box alignment and improves RGB color fidelity over state-of-the-art baselines. More broadly, our results support a new paradigm in which user intent is translated into an intermediate structured language, consumed by a flow-based transformer acting as a renderer and naturally accommodating numeric parameters.

Matching of SAR and optical images based on transformation to shared modality

Significant differences in optical images and Synthetic Aperture Radar (SAR) images are caused by fundamental differences in the physical principles underlying their acquisition by Earth remote sensing platforms. These differences make precise image matching (co-registration) of these two types of images difficult. In this paper, we propose a new approach to image matching of optical and SAR images, which is based on transforming the images to a new modality. The new image modality is common to both optical and SAR images and satisfies the following conditions. First, the transformed images must have an equal pre-defined number of channels. Second, the transformed and co-registered images must be as similar as possible. Third, the transformed images must be non-degenerate, meaning they must preserve the significant features of the original images. To further match images transformed to this shared modality, we train the RoMa image matching model, which is one of the leading solutions for matching of regular digital photographs. We evaluated the proposed approach on the publicly available MultiSenGE dataset containing both optical and SAR images. We demonstrated its superiority over alternative approaches based on image translation between original modalities and various feature matching algorithms. The proposed solution not only provides better quality of matching, but is also more versatile. It enables the use of ready-made RoMa and DeDoDe models, pre-trained for regular images, without retraining for a new modality, while maintaining high-quality matching of optical and SAR images.

Using Deep Learning to Generate Semantically Correct Hindi Captions

Automated image captioning using the content from the image is very appealing when done by harnessing the capability of computer vision and natural language processing. Extensive research has been done in the field with a major focus on the English language which gives the scope for further developments in the same with consideration of popular foreign languages. This research utilizes distinct models for translating the image caption into Hindi, the fourth most popular language across the world. Exploring the multi-modal architectures this research comprises local visual features, global visual features, attention mechanisms, and pre-trained models. Using google cloud translator on the image dataset from Flickr8k, Hindi image descriptions have been generated. Pre-trained CNNs like VGG16, ResNet50, and Inception V3 helped in retrieving image characteristics, while the uni-directional and bi-directional techniques of text encoding are used for the text encoding process. An additional Attention layer helps to generate a weight vector and, by multiplying it, combine image characteristics from each time step into a sentence-level feature vector. Bilingual evaluation understudy scores are used to compare the research outcome. Many experiments that serve as a baseline are done for the comparative analysis of the research. An image with a score of BLEU-1 is considered sufficient, whereas one with a score of BLEU-4 is considered to have fluid image captioning. For both BLEU scores, the attention-based bidirectional LSTM with VGG16 produced the best results of 0.59 and 0.19 respectively. The experiments conclude that researchs ability to produce relevant, semantically accurate image captions in Hindi. The research accomplishes the goals and future research can be guided by this research model.