VI-MMRec: Similarity-Aware Training Cost-free Virtual User-Item Interactions for Multimodal Recommendation

Although existing multimodal recommendation models have shown promising performance, their effectiveness continues to be limited by the pervasive data sparsity problem. This problem arises because users typically interact with only a small subset of available items, leading existing models to arbitrarily treat unobserved items as negative samples. To this end, we propose VI-MMRec, a model-agnostic and training cost-free framework that enriches sparse user-item interactions via similarity-aware virtual user-item interactions. These virtual interactions are constructed based on modality-specific feature similarities of user-interacted items. Specifically, VI-MMRec introduces two different strategies: (1) Overlay, which independently aggregates modality-specific similarities to preserve modality-specific user preferences, and (2) Synergistic, which holistically fuses cross-modal similarities to capture complementary user preferences. To ensure high-quality augmentation, we design a statistically informed weight allocation mechanism that adaptively assigns weights to virtual user-item interactions based on dataset-specific modality relevance. As a plug-and-play framework, VI-MMRec seamlessly integrates with existing models to enhance their performance without modifying their core architecture. Its flexibility allows it to be easily incorporated into various existing models, maximizing performance with minimal implementation effort. Moreover, VI-MMRec introduces no additional overhead during training, making it significantly advantageous for practical deployment. Comprehensive experiments conducted on six real-world datasets using seven state-of-the-art multimodal recommendation models validate the effectiveness of our VI-MMRec.

Calibrated Trust in Dealing with LLM Hallucinations: A Qualitative Study

Hallucinations are outputs by Large Language Models (LLMs) that are factually incorrect yet appear plausible [1]. This paper investigates how such hallucinations influence users' trust in LLMs and users' interaction with LLMs. To explore this in everyday use, we conducted a qualitative study with 192 participants. Our findings show that hallucinations do not result in blanket mistrust but instead lead to context-sensitive trust calibration. Building on the calibrated trust model by Lee & See [2] and Afroogh et al.'s trust-related factors [3], we confirm expectancy [3], [4], prior experience [3], [4], [5], and user expertise & domain knowledge [3], [4] as userrelated (human) trust factors, and identify intuition as an additional factor relevant for hallucination detection. Additionally, we found that trust dynamics are further influenced by contextual factors, particularly perceived risk [3] and decision stakes [6]. Consequently, we validate the recursive trust calibration process proposed by Blöbaum [7] and extend it by including intuition as a user-related trust factor. Based on these insights, we propose practical recommendations for responsible and reflective LLM use.

Generalization vs. Specialization: Evaluating Segment Anything Model (SAM3) Zero-Shot Segmentation Against Fine-Tuned YOLO Detectors

Deep learning has advanced two fundamentally different paradigms for instance segmentation: specialized models optimized through task-specific fine-tuning and generalist foundation models capable of zero-shot segmentation. This work presents a comprehensive comparison between SAM3 (Segment Anything Model, also called SAMv3) operating in zero-shot mode and three variants of Ultralytics YOLO11 (nano, medium, and large) fine-tuned for instance segmentation. The evaluation is conducted on the MinneApple dataset, a dense benchmark comprising 670 orchard images with 28,179 annotated apple instances, enabling rigorous validation of model behavior under high object density and occlusion. Our analysis shows IoU choices can inflate performance gaps by up to 30%. At the appropriate IoU = 0.15 threshold, YOLO models achieve 68.9%, 72.2%, and 71.9% F1, while SAM3 reaches 59.8% in pure zero-shot mode. However, YOLO exhibits steep degradation 48-50 points across IoU ranges whereas SAM3 drops only 4 points, revealing 12 times superior boundary stability of SAM3. This highlights the strength of SAMv3 in mask precision versus specialization in detection completeness of YOLO11. We provide open-source code, evaluation pipelines, and methodological recommendations, contributing to a deeper understanding of when specialized fine-tuned models or generalist foundation models are preferable for dense instance segmentation tasks. This project repository is available on GitHub as https://github.com/Applied-AI-Research-Lab/Segment-Anything-Model-SAM3-Zero-Shot-Segmentation-Against-Fine-Tuned-YOLO-Detectors

CLARITY: Medical World Model for Guiding Treatment Decisions by Modeling Context-Aware Disease Trajectories in Latent Space

Clinical decision-making in oncology requires predicting dynamic disease evolution, a task current static AI predictors cannot perform. While world models (WMs) offer a paradigm for generative prediction, existing medical applications remain limited. Existing methods often rely on stochastic diffusion models, focusing on visual reconstruction rather than causal, physiological transitions. Furthermore, in medical domain, models like MeWM typically ignore patient-specific temporal and clinical contexts and lack a feedback mechanism to link predictions to treatment decisions. To address these gaps, we introduce CLARITY, a medical world model that forecasts disease evolution directly within a structured latent space. It explicitly integrates time intervals (temporal context) and patient-specific data (clinical context) to model treatment-conditioned progression as a smooth, interpretable trajectory, and thus generate physiologically faithful, individualized treatment plans. Finally, CLARITY introduces a novel prediction-to-decision framework, translating latent rollouts into transparent, actionable recommendations. CLARITY demonstrates state-of-the-art performance in treatment planning. On the MU-Glioma-Post dataset, our approach outperforms recent MeWM by 12\%, and significantly surpasses all other medical-specific large language models.

MUSE: A Simple Yet Effective Multimodal Search-Based Framework for Lifelong User Interest Modeling

Lifelong user interest modeling is crucial for industrial recommender systems, yet existing approaches rely predominantly on ID-based features, suffering from poor generalization on long-tail items and limited semantic expressiveness. While recent work explores multimodal representations for behavior retrieval in the General Search Unit (GSU), they often neglect multimodal integration in the fine-grained modeling stage -- the Exact Search Unit (ESU). In this work, we present a systematic analysis of how to effectively leverage multimodal signals across both stages of the two-stage lifelong modeling framework. Our key insight is that simplicity suffices in the GSU: lightweight cosine similarity with high-quality multimodal embeddings outperforms complex retrieval mechanisms. In contrast, the ESU demands richer multimodal sequence modeling and effective ID-multimodal fusion to unlock its full potential. Guided by these principles, we propose MUSE, a simple yet effective multimodal search-based framework. MUSE has been deployed in Taobao display advertising system, enabling 100K-length user behavior sequence modeling and delivering significant gains in top-line metrics with negligible online latency overhead. To foster community research, we share industrial deployment practices and open-source the first large-scale dataset featuring ultra-long behavior sequences paired with high-quality multimodal embeddings. Our code and data is available at https://taobao-mm.github.io.

On the Impact of Graph Neural Networks in Recommender Systems: A Topological Perspective

In recommender systems, user-item interactions can be modeled as a bipartite graph, where user and item nodes are connected by undirected edges. This graph-based view has motivated the rapid adoption of graph neural networks (GNNs), which often outperform collaborative filtering (CF) methods such as latent factor models, deep neural networks, and generative strategies. Yet, despite their empirical success, the reasons why GNNs offer systematic advantages over other CF approaches remain only partially understood. This monograph advances a topology-centered perspective on GNN-based recommendation. We argue that a comprehensive understanding of these models' performance should consider the structural properties of user-item graphs and their interaction with GNN architectural design. To support this view, we introduce a formal taxonomy that distills common modeling patterns across eleven representative GNN-based recommendation approaches and consolidates them into a unified conceptual pipeline. We further formalize thirteen classical and topological characteristics of recommendation datasets and reinterpret them through the lens of graph machine learning. Using these definitions, we analyze the considered GNN-based recommender architectures to assess how and to what extent they encode such properties. Building on this analysis, we derive an explanatory framework that links measurable dataset characteristics to model behavior and performance. Taken together, this monograph re-frames GNN-based recommendation through its topological underpinnings and outlines open theoretical, data-centric, and evaluation challenges for the next generation of topology-aware recommender systems.

Toward an AI Reasoning-Enabled System for Patient-Clinical Trial Matching

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that addresses key implementation challenges: integrating heterogeneous electronic health record (EHR) data, facilitating expert review, and maintaining rigorous security standards. Leveraging open-source, reasoning-enabled large language models (LLMs), the system moves beyond binary classification to generate structured eligibility assessments with interpretable reasoning chains that support human-in-the-loop review. This decision support tool represents eligibility as a dynamic state rather than a fixed determination, identifying matches when available and offering actionable recommendations that could render a patient eligible in the future. The system aims to reduce coordinator burden, intelligently broaden the set of trials considered for each patient and guarantee comprehensive auditability of all AI-generated outputs.

Bridging the Clinical Expertise Gap: Development of a Web-Based Platform for Accessible Time Series Forecasting and Analysis

Time series forecasting has applications across domains and industries, especially in healthcare, but the technical expertise required to analyze data, build models, and interpret results can be a barrier to using these techniques. This article presents a web platform that makes the process of analyzing and plotting data, training forecasting models, and interpreting and viewing results accessible to researchers and clinicians. Users can upload data and generate plots to showcase their variables and the relationships between them. The platform supports multiple forecasting models and training techniques which are highly customizable according to the user's needs. Additionally, recommendations and explanations can be generated from a large language model that can help the user choose appropriate parameters for their data and understand the results for each model. The goal is to integrate this platform into learning health systems for continuous data collection and inference from clinical pipelines.

Auditing Games for Sandbagging

Future AI systems could conceal their capabilities ('sandbagging') during evaluations, potentially misleading developers and auditors. We stress-tested sandbagging detection techniques using an auditing game. First, a red team fine-tuned five models, some of which conditionally underperformed, as a proxy for sandbagging. Second, a blue team used black-box, model-internals, or training-based approaches to identify sandbagging models. We found that the blue team could not reliably discriminate sandbaggers from benign models. Black-box approaches were defeated by effective imitation of a weaker model. Linear probes, a model-internals approach, showed more promise but their naive application was vulnerable to behaviours instilled by the red team. We also explored capability elicitation as a strategy for detecting sandbagging. Although Prompt-based elicitation was not reliable, training-based elicitation consistently elicited full performance from the sandbagging models, using only a single correct demonstration of the evaluation task. However the performance of benign models was sometimes also raised, so relying on elicitation as a detection strategy was prone to false-positives. In the short-term, we recommend developers remove potential sandbagging using on-distribution training for elicitation. In the longer-term, further research is needed to ensure the efficacy of training-based elicitation, and develop robust methods for sandbagging detection. We open source our model organisms at https://github.com/AI-Safety-Institute/sandbagging_auditing_games and select transcripts and results at https://huggingface.co/datasets/sandbagging-games/evaluation_logs . A demo illustrating the game can be played at https://sandbagging-demo.far.ai/ .

Automated Generation of Custom MedDRA Queries Using SafeTerm Medical Map

In pre-market drug safety review, grouping related adverse event terms into standardised MedDRA queries or the FDA Office of New Drugs Custom Medical Queries (OCMQs) is critical for signal detection. We present a novel quantitative artificial intelligence system that understands and processes medical terminology and automatically retrieves relevant MedDRA Preferred Terms (PTs) for a given input query, ranking them by a relevance score using multi-criteria statistical methods. The system (SafeTerm) embeds medical query terms and MedDRA PTs in a multidimensional vector space, then applies cosine similarity and extreme-value clustering to generate a ranked list of PTs. Validation was conducted against the FDA OCMQ v3.0 (104 queries), restricted to valid MedDRA PTs. Precision, recall and F1 were computed across similarity-thresholds. High recall (>95%) is achieved at moderate thresholds. Higher thresholds improve precision (up to 86%). The optimal threshold (~0.70 - 0.75) yielded recall ~50% and precision ~33%. Narrow-term PT subsets performed similarly but required slightly higher similarity thresholds. The SafeTerm AI-driven system provides a viable supplementary method for automated MedDRA query generation. A similarity threshold of ~0.60 is recommended initially, with increased thresholds for refined term selection.