Early Autism Diagnosis based on Path Signature and Siamese Unsupervised Feature Compressor

Autism Spectrum Disorder (ASD) has been emerging as a growing public health threat. Early diagnosis of ASD is crucial for timely, effective intervention and treatment. However, conventional diagnosis methods based on communications and behavioral patterns are unreliable for children younger than 2 years of age. Given evidences of neurodevelopmental abnormalities in ASD infants, we resort to a novel deep learning-based method to extract key features from the inherently scarce, class-imbalanced, and heterogeneous structural MR images for early autism diagnosis. Specifically, we propose a Siamese verification framework to extend the scarce data, and an unsupervised compressor to alleviate data imbalance by extracting key features. We also proposed weight constraints to cope with sample heterogeneity by giving different samples different voting weights during validation, and we used Path Signature to unravel meaningful developmental features from the two-time point data longitudinally. Extensive experiments have shown that our method performed well under practical scenarios, transcending existing machine learning methods.

A generic self-supervised learning (SSL) framework for representation learning from spectra-spatial feature of unlabeled remote sensing imagery

Remote sensing data has been widely used for various Earth Observation (EO) missions such as land use and cover classification, weather forecasting, agricultural management, and environmental monitoring. Most existing remote sensing data-based models are based on supervised learning that requires large and representative human-labelled data for model training, which is costly and time-consuming. Recently, self-supervised learning (SSL) enables the models to learn a representation from orders of magnitude more unlabelled data. This representation has been proven to boost the performance of downstream tasks and has potential for remote sensing applications. The success of SSL is heavily dependent on a pre-designed pretext task, which introduces an inductive bias into the model from a large amount of unlabelled data. Since remote sensing imagery has rich spectral information beyond the standard RGB colour space, the pretext tasks established in computer vision based on RGB images may not be straightforward to be extended to the multi/hyperspectral domain. To address this challenge, this work has designed a novel SSL framework that is capable of learning representation from both spectra-spatial information of unlabelled data. The framework contains two novel pretext tasks for object-based and pixel-based remote sensing data analysis methods, respectively. Through two typical downstream tasks evaluation (a multi-label land cover classification task on Sentienl-2 multispectral datasets and a ground soil parameter retrieval task on hyperspectral datasets), the results demonstrate that the representation obtained through the proposed SSL achieved a significant improvement in model performance.

SHISRCNet: Super-resolution And Classification Network For Low-resolution Breast Cancer Histopathology Image

The rapid identification and accurate diagnosis of breast cancer, known as the killer of women, have become greatly significant for those patients. Numerous breast cancer histopathological image classification methods have been proposed. But they still suffer from two problems. (1) These methods can only hand high-resolution (HR) images. However, the low-resolution (LR) images are often collected by the digital slide scanner with limited hardware conditions. Compared with HR images, LR images often lose some key features like texture, which deeply affects the accuracy of diagnosis. (2) The existing methods have fixed receptive fields, so they can not extract and fuse multi-scale features well for images with different magnification factors. To fill these gaps, we present a \textbf{S}ingle \textbf{H}istopathological \textbf{I}mage \textbf{S}uper-\textbf{R}esolution \textbf{C}lassification network (SHISRCNet), which consists of two modules: Super-Resolution (SR) and Classification (CF) modules. SR module reconstructs LR images into SR ones. CF module extracts and fuses the multi-scale features of SR images for classification. In the training stage, we introduce HR images into the CF module to enhance SHISRCNet's performance. Finally, through the joint training of these two modules, super-resolution and classified of LR images are integrated into our model. The experimental results demonstrate that the effects of our method are close to the SOTA methods with taking HR images as inputs.

GICI-LIB: A GNSS/INS/Camera Integrated Navigation Library

Accurate navigation is essential for autonomous robots and vehicles. In recent years, the integration of the Global Navigation Satellite System (GNSS), Inertial Navigation System (INS), and camera has garnered considerable attention due to its robustness and high accuracy in diverse environments. In such systems, fully utilizing the role of GNSS is cumbersome because of the diverse choices of formulations, error models, satellite constellations, signal frequencies, and service types, which lead to different precision, robustness, and usage dependencies. To clarify the capacity of GNSS algorithms and accelerate the development efficiency of employing GNSS in multi-sensor fusion algorithms, we open source the GNSS/INS/Camera Integration Library (GICI-LIB), together with detailed documentation and a comprehensive land vehicle dataset. A factor graph optimization-based multi-sensor fusion framework is established, which combines almost all GNSS measurement error sources by fully considering temporal and spatial correlations between measurements. The graph structure is designed for flexibility, making it easy to form any kind of integration algorithm. For illustration, four Real-Time Kinematic (RTK)-based algorithms from GICI-LIB are evaluated using our dataset. Results confirm the potential of the GICI system to provide continuous precise navigation solutions in a wide spectrum of urban environments.

Attention Hybrid Variational Net for Accelerated MRI Reconstruction

The application of compressed sensing (CS)-enabled data reconstruction for accelerating magnetic resonance imaging (MRI) remains a challenging problem. This is due to the fact that the information lost in k-space from the acceleration mask makes it difficult to reconstruct an image similar to the quality of a fully sampled image. Multiple deep learning-based structures have been proposed for MRI reconstruction using CS, both in the k-space and image domains as well as using unrolled optimization methods. However, the drawback of these structures is that they are not fully utilizing the information from both domains (k-space and image). Herein, we propose a deep learning-based attention hybrid variational network that performs learning in both the k-space and image domain. We evaluate our method on a well-known open-source MRI dataset and a clinical MRI dataset of patients diagnosed with strokes from our institution to demonstrate the performance of our network. In addition to quantitative evaluation, we undertook a blinded comparison of image quality across networks performed by a subspecialty trained radiologist. Overall, we demonstrate that our network achieves a superior performance among others under multiple reconstruction tasks.

Paste, Inpaint and Harmonize via Denoising: Subject-Driven Image Editing with Pre-Trained Diffusion Model

Text-to-image generative models have attracted rising attention for flexible image editing via user-specified descriptions. However, text descriptions alone are not enough to elaborate the details of subjects, often compromising the subjects' identity or requiring additional per-subject fine-tuning. We introduce a new framework called \textit{Paste, Inpaint and Harmonize via Denoising} (PhD), which leverages an exemplar image in addition to text descriptions to specify user intentions. In the pasting step, an off-the-shelf segmentation model is employed to identify a user-specified subject within an exemplar image which is subsequently inserted into a background image to serve as an initialization capturing both scene context and subject identity in one. To guarantee the visual coherence of the generated or edited image, we introduce an inpainting and harmonizing module to guide the pre-trained diffusion model to seamlessly blend the inserted subject into the scene naturally. As we keep the pre-trained diffusion model frozen, we preserve its strong image synthesis ability and text-driven ability, thus achieving high-quality results and flexible editing with diverse texts. In our experiments, we apply PhD to both subject-driven image editing tasks and explore text-driven scene generation given a reference subject. Both quantitative and qualitative comparisons with baseline methods demonstrate that our approach achieves state-of-the-art performance in both tasks. More qualitative results can be found at \url{https://sites.google.com/view/phd-demo-page}.

Deep learning radiomics for assessment of gastroesophageal varices in people with compensated advanced chronic liver disease

Objective: Bleeding from gastroesophageal varices (GEV) is a medical emergency associated with high mortality. We aim to construct an artificial intelligence-based model of two-dimensional shear wave elastography (2D-SWE) of the liver and spleen to precisely assess the risk of GEV and high-risk gastroesophageal varices (HRV). Design: A prospective multicenter study was conducted in patients with compensated advanced chronic liver disease. 305 patients were enrolled from 12 hospitals, and finally 265 patients were included, with 1136 liver stiffness measurement (LSM) images and 1042 spleen stiffness measurement (SSM) images generated by 2D-SWE. We leveraged deep learning methods to uncover associations between image features and patient risk, and thus conducted models to predict GEV and HRV. Results: A multi-modality Deep Learning Risk Prediction model (DLRP) was constructed to assess GEV and HRV, based on LSM and SSM images, and clinical information. Validation analysis revealed that the AUCs of DLRP were 0.91 for GEV (95% CI 0.90 to 0.93, p < 0.05) and 0.88 for HRV (95% CI 0.86 to 0.89, p < 0.01), which were significantly and robustly better than canonical risk indicators, including the value of LSM and SSM. Moreover, DLPR was better than the model using individual parameters, including LSM and SSM images. In HRV prediction, the 2D-SWE images of SSM outperform LSM (p < 0.01). Conclusion: DLRP shows excellent performance in predicting GEV and HRV over canonical risk indicators LSM and SSM. Additionally, the 2D-SWE images of SSM provided more information for better accuracy in predicting HRV than the LSM.

ELSA: Efficient Label Shift Adaptation through the Lens of Semiparametric Models

We study the domain adaptation problem with label shift in this work. Under the label shift context, the marginal distribution of the label varies across the training and testing datasets, while the conditional distribution of features given the label is the same. Traditional label shift adaptation methods either suffer from large estimation errors or require cumbersome post-prediction calibrations. To address these issues, we first propose a moment-matching framework for adapting the label shift based on the geometry of the influence function. Under such a framework, we propose a novel method named \underline{E}fficient \underline{L}abel \underline{S}hift \underline{A}daptation (ELSA), in which the adaptation weights can be estimated by solving linear systems. Theoretically, the ELSA estimator is $\sqrt{n}$-consistent ($n$ is the sample size of the source data) and asymptotically normal. Empirically, we show that ELSA can achieve state-of-the-art estimation performances without post-prediction calibrations, thus, gaining computational efficiency.

GDA: Generative Data Augmentation Techniques for Relation Extraction Tasks

Relation extraction (RE) tasks show promising performance in extracting relations from two entities mentioned in sentences, given sufficient annotations available during training. Such annotations would be labor-intensive to obtain in practice. Existing work adopts data augmentation techniques to generate pseudo-annotated sentences beyond limited annotations. These techniques neither preserve the semantic consistency of the original sentences when rule-based augmentations are adopted, nor preserve the syntax structure of sentences when expressing relations using seq2seq models, resulting in less diverse augmentations. In this work, we propose a dedicated augmentation technique for relational texts, named GDA, which uses two complementary modules to preserve both semantic consistency and syntax structures. We adopt a generative formulation and design a multi-tasking solution to achieve synergies. Furthermore, GDA adopts entity hints as the prior knowledge of the generative model to augment diverse sentences. Experimental results in three datasets under a low-resource setting showed that GDA could bring {\em 2.0\%} F1 improvements compared with no augmentation technique. Source code and data are available.

SpeechGPT: Empowering Large Language Models with Intrinsic Cross-Modal Conversational Abilities

Multi-modal large language models are regarded as a crucial step towards Artificial General Intelligence (AGI) and have garnered significant interest with the emergence of ChatGPT. However, current speech-language models typically adopt the cascade paradigm, preventing inter-modal knowledge transfer. In this paper, we propose SpeechGPT, a large language model with intrinsic cross-modal conversational abilities, capable of perceiving and generating multi-model content. With discrete speech representations, we first construct SpeechInstruct, a large-scale cross-modal speech instruction dataset. Additionally, we employ a three-stage training strategy that includes modality-adaptation pre-training, cross-modal instruction fine-tuning, and chain-of-modality instruction fine-tuning. The experimental results demonstrate that SpeechGPT has an impressive capacity to follow multi-modal human instructions and highlight the potential of handling multiple modalities with one model. Demos are shown in https://0nutation.github.io/SpeechGPT.github.io/.