ScaleFold: Reducing AlphaFold Initial Training Time to 10 Hours

AlphaFold2 has been hailed as a breakthrough in protein folding. It can rapidly predict protein structures with lab-grade accuracy. However, its implementation does not include the necessary training code. OpenFold is the first trainable public reimplementation of AlphaFold. AlphaFold training procedure is prohibitively time-consuming, and gets diminishing benefits from scaling to more compute resources. In this work, we conducted a comprehensive analysis on the AlphaFold training procedure based on Openfold, identified that inefficient communications and overhead-dominated computations were the key factors that prevented the AlphaFold training from effective scaling. We introduced ScaleFold, a systematic training method that incorporated optimizations specifically for these factors. ScaleFold successfully scaled the AlphaFold training to 2080 NVIDIA H100 GPUs with high resource utilization. In the MLPerf HPC v3.0 benchmark, ScaleFold finished the OpenFold benchmark in 7.51 minutes, shown over $6\times$ speedup than the baseline. For training the AlphaFold model from scratch, ScaleFold completed the pretraining in 10 hours, a significant improvement over the seven days required by the original AlphaFold pretraining baseline.

Joint Intrinsic and Extrinsic LiDAR-Camera Calibration in Targetless Environments Using Plane-Constrained Bundle Adjustment

This paper introduces a novel targetless method for joint intrinsic and extrinsic calibration of LiDAR-camera systems using plane-constrained bundle adjustment (BA). Our method leverages LiDAR point cloud measurements from planes in the scene, alongside visual points derived from those planes. The core novelty of our method lies in the integration of visual BA with the registration between visual points and LiDAR point cloud planes, which is formulated as a unified optimization problem. This formulation achieves concurrent intrinsic and extrinsic calibration, while also imparting depth constraints to the visual points to enhance the accuracy of intrinsic calibration. Experiments are conducted on both public data sequences and self-collected dataset. The results showcase that our approach not only surpasses other state-of-the-art (SOTA) methods but also maintains remarkable calibration accuracy even within challenging environments. For the benefits of the robotics community, we have open sourced our codes.

Zoom Out and Observe: News Environment Perception for Fake News Detection

Fake news detection is crucial for preventing the dissemination of misinformation on social media. To differentiate fake news from real ones, existing methods observe the language patterns of the news post and "zoom in" to verify its content with knowledge sources or check its readers' replies. However, these methods neglect the information in the external news environment where a fake news post is created and disseminated. The news environment represents recent mainstream media opinion and public attention, which is an important inspiration of fake news fabrication because fake news is often designed to ride the wave of popular events and catch public attention with unexpected novel content for greater exposure and spread. To capture the environmental signals of news posts, we "zoom out" to observe the news environment and propose the News Environment Perception Framework (NEP). For each post, we construct its macro and micro news environment from recent mainstream news. Then we design a popularity-oriented and a novelty-oriented module to perceive useful signals and further assist final prediction. Experiments on our newly built datasets show that the NEP can efficiently improve the performance of basic fake news detectors.

Confidence Propagation Cluster: Unleash Full Potential of Object Detectors

It has been a long history that most object detection methods obtain objects by using the non-maximum suppression (NMS) and its improved versions like Soft-NMS to remove redundant bounding boxes. We challenge those NMS-based methods from three aspects: 1) The bounding box with highest confidence value may not be the true positive having the biggest overlap with the ground-truth box. 2) Not only suppression is required for redundant boxes, but also confidence enhancement is needed for those true positives. 3) Sorting candidate boxes by confidence values is not necessary so that full parallelism is achievable. In this paper, inspired by belief propagation (BP), we propose the Confidence Propagation Cluster (CP-Cluster) to replace NMS-based methods, which is fully parallelizable as well as better in accuracy. In CP-Cluster, we borrow the message passing mechanism from BP to penalize redundant boxes and enhance true positives simultaneously in an iterative way until convergence. We verified the effectiveness of CP-Cluster by applying it to various mainstream detectors such as FasterRCNN, SSD, FCOS, YOLOv3, YOLOv5, Centernet etc. Experiments on MS COCO show that our plug and play method, without retraining detectors, is able to steadily improve average mAP of all those state-of-the-art models with a clear margin from 0.2 to 1.9 respectively when compared with NMS-based methods. Source code is available at https://github.com/shenyi0220/CP-Cluster