Partial-to-Full Registration based on Gradient-SDF for Computer-Assisted Orthopedic Surgery

In computer-assisted orthopedic surgery (CAOS), accurate pre-operative to intra-operative bone registration is an essential and critical requirement for providing navigational guidance. This registration process is challenging since the intra-operative 3D points are sparse, only partially overlapped with the pre-operative model, and disturbed by noise and outliers. The commonly used method in current state-of-the-art orthopedic robotic system is bony landmarks based registration, but it is very time-consuming for the surgeons. To address these issues, we propose a novel partial-to-full registration framework based on gradient-SDF for CAOS. The simulation experiments using bone models from publicly available datasets and the phantom experiments performed under both optical tracking and electromagnetic tracking systems demonstrate that the proposed method can provide more accurate results than standard benchmarks and be robust to 90% outliers. Importantly, our method achieves convergence in less than 1 second in real scenarios and mean target registration error values as low as 2.198 mm for the entire bone model. Finally, it only requires random acquisition of points for registration by moving a surgical probe over the bone surface without correspondence with any specific bony landmarks, thus showing significant potential clinical value.

HiReview: Hierarchical Taxonomy-Driven Automatic Literature Review Generation

In this work, we present HiReview, a novel framework for hierarchical taxonomy-driven automatic literature review generation. With the exponential growth of academic documents, manual literature reviews have become increasingly labor-intensive and time-consuming, while traditional summarization models struggle to generate comprehensive document reviews effectively. Large language models (LLMs), with their powerful text processing capabilities, offer a potential solution; however, research on incorporating LLMs for automatic document generation remains limited. To address key challenges in large-scale automatic literature review generation (LRG), we propose a two-stage taxonomy-then-generation approach that combines graph-based hierarchical clustering with retrieval-augmented LLMs. First, we retrieve the most relevant sub-community within the citation network, then generate a hierarchical taxonomy tree by clustering papers based on both textual content and citation relationships. In the second stage, an LLM generates coherent and contextually accurate summaries for clusters or topics at each hierarchical level, ensuring comprehensive coverage and logical organization of the literature. Extensive experiments demonstrate that HiReview significantly outperforms state-of-the-art methods, achieving superior hierarchical organization, content relevance, and factual accuracy in automatic literature review generation tasks.

Few-Shot Class-Incremental Learning with Non-IID Decentralized Data

Few-shot class-incremental learning is crucial for developing scalable and adaptive intelligent systems, as it enables models to acquire new classes with minimal annotated data while safeguarding the previously accumulated knowledge. Nonetheless, existing methods deal with continuous data streams in a centralized manner, limiting their applicability in scenarios that prioritize data privacy and security. To this end, this paper introduces federated few-shot class-incremental learning, a decentralized machine learning paradigm tailored to progressively learn new classes from scarce data distributed across multiple clients. In this learning paradigm, clients locally update their models with new classes while preserving data privacy, and then transmit the model updates to a central server where they are aggregated globally. However, this paradigm faces several issues, such as difficulties in few-shot learning, catastrophic forgetting, and data heterogeneity. To address these challenges, we present a synthetic data-driven framework that leverages replay buffer data to maintain existing knowledge and facilitate the acquisition of new knowledge. Within this framework, a noise-aware generative replay module is developed to fine-tune local models with a balance of new and replay data, while generating synthetic data of new classes to further expand the replay buffer for future tasks. Furthermore, a class-specific weighted aggregation strategy is designed to tackle data heterogeneity by adaptively aggregating class-specific parameters based on local models performance on synthetic data. This enables effective global model optimization without direct access to client data. Comprehensive experiments across three widely-used datasets underscore the effectiveness and preeminence of the introduced framework.

A Unified Approach to Inferring Chemical Compounds with the Desired Aqueous Solubility

Aqueous solubility (AS) is a key physiochemical property that plays a crucial role in drug discovery and material design. We report a novel unified approach to predict and infer chemical compounds with the desired AS based on simple deterministic graph-theoretic descriptors, multiple linear regression (MLR) and mixed integer linear programming (MILP). Selected descriptors based on a forward stepwise procedure enabled the simplest regression model, MLR, to achieve significantly good prediction accuracy compared to the existing approaches, achieving the accuracy in the range [0.7191, 0.9377] for 29 diverse datasets. By simulating these descriptors and learning models as MILPs, we inferred mathematically exact and optimal compounds with the desired AS, prescribed structures, and up to 50 non-hydrogen atoms in a reasonable time range [6, 1204] seconds. These findings indicate a strong correlation between the simple graph-theoretic descriptors and the AS of compounds, potentially leading to a deeper understanding of their AS without relying on widely used complicated chemical descriptors and complex machine learning models that are computationally expensive, and therefore difficult to use for inference. An implementation of the proposed approach is available at https://github.com/ku-dml/mol-infer/tree/master/AqSol.

LibMOON: A Gradient-based MultiObjective OptimizatioN Library in PyTorch

Multiobjective optimization problems (MOPs) are prevalent in machine learning, with applications in multi-task learning, learning under fairness or robustness constraints, etc. Instead of reducing multiple objective functions into a scalar objective, MOPs aim to optimize for the so-called Pareto optimality or Pareto set learning, which involves optimizing more than one objective function simultaneously, over models with millions of parameters. Existing benchmark libraries for MOPs mainly focus on evolutionary algorithms, most of which are zeroth-order methods that do not effectively utilize higher-order information from objectives and cannot scale to large-scale models with millions of parameters. In light of the above gap, this paper introduces LibMOON, the first multiobjective optimization library that supports state-of-the-art gradient-based methods, provides a fair benchmark, and is open-sourced for the community.

4D-CAT: Synthesis of 4D Coronary Artery Trees from Systole and Diastole

The three-dimensional vascular model reconstructed from CT images is widely used in medical diagnosis. At different phases, the beating of the heart can cause deformation of vessels, resulting in different vascular imaging states and false positive diagnostic results. The 4D model can simulate a complete cardiac cycle. Due to the dose limitation of contrast agent injection in patients, it is valuable to synthesize a 4D coronary artery trees through finite phases imaging. In this paper, we propose a method for generating a 4D coronary artery trees, which maps the systole to the diastole through deformation field prediction, interpolates on the timeline, and the motion trajectory of points are obtained. Specifically, the centerline is used to represent vessels and to infer deformation fields using cube-based sorting and neural networks. Adjacent vessel points are aggregated and interpolated based on the deformation field of the centerline point to obtain displacement vectors of different phases. Finally, the proposed method is validated through experiments to achieve the registration of non-rigid vascular points and the generation of 4D coronary trees.

General OCR Theory: Towards OCR-2.0 via a Unified End-to-end Model

Traditional OCR systems (OCR-1.0) are increasingly unable to meet people's usage due to the growing demand for intelligent processing of man-made optical characters. In this paper, we collectively refer to all artificial optical signals (e.g., plain texts, math/molecular formulas, tables, charts, sheet music, and even geometric shapes) as "characters" and propose the General OCR Theory along with an excellent model, namely GOT, to promote the arrival of OCR-2.0. The GOT, with 580M parameters, is a unified, elegant, and end-to-end model, consisting of a high-compression encoder and a long-contexts decoder. As an OCR-2.0 model, GOT can handle all the above "characters" under various OCR tasks. On the input side, the model supports commonly used scene- and document-style images in slice and whole-page styles. On the output side, GOT can generate plain or formatted results (markdown/tikz/smiles/kern) via an easy prompt. Besides, the model enjoys interactive OCR features, i.e., region-level recognition guided by coordinates or colors. Furthermore, we also adapt dynamic resolution and multi-page OCR technologies to GOT for better practicality. In experiments, we provide sufficient results to prove the superiority of our model.

Representation Learning of Geometric Trees

Geometric trees are characterized by their tree-structured layout and spatially constrained nodes and edges, which significantly impacts their topological attributes. This inherent hierarchical structure plays a crucial role in domains such as neuron morphology and river geomorphology, but traditional graph representation methods often overlook these specific characteristics of tree structures. To address this, we introduce a new representation learning framework tailored for geometric trees. It first features a unique message passing neural network, which is both provably geometrical structure-recoverable and rotation-translation invariant. To address the data label scarcity issue, our approach also includes two innovative training targets that reflect the hierarchical ordering and geometric structure of these geometric trees. This enables fully self-supervised learning without explicit labels. We validate our method's effectiveness on eight real-world datasets, demonstrating its capability to represent geometric trees.

Cycle-Configuration: A Novel Graph-theoretic Descriptor Set for Molecular Inference

In this paper, we propose a novel family of descriptors of chemical graphs, named cycle-configuration (CC), that can be used in the standard "two-layered (2L) model" of mol-infer, a molecular inference framework based on mixed integer linear programming (MILP) and machine learning (ML). Proposed descriptors capture the notion of ortho/meta/para patterns that appear in aromatic rings, which has been impossible in the framework so far. Computational experiments show that, when the new descriptors are supplied, we can construct prediction functions of similar or better performance for all of the 27 tested chemical properties. We also provide an MILP formulation that asks for a chemical graph with desired properties under the 2L model with CC descriptors (2L+CC model). We show that a chemical graph with up to 50 non-hydrogen vertices can be inferred in a practical time.

Contrastive Learning for Image Complexity Representation

Quantifying and evaluating image complexity can be instrumental in enhancing the performance of various computer vision tasks. Supervised learning can effectively learn image complexity features from well-annotated datasets. However, creating such datasets requires expensive manual annotation costs. The models may learn human subjective biases from it. In this work, we introduce the MoCo v2 framework. We utilize contrastive learning to represent image complexity, named CLIC (Contrastive Learning for Image Complexity). We find that there are complexity differences between different local regions of an image, and propose Random Crop and Mix (RCM), which can produce positive samples consisting of multi-scale local crops. RCM can also expand the train set and increase data diversity without introducing additional data. We conduct extensive experiments with CLIC, comparing it with both unsupervised and supervised methods. The results demonstrate that the performance of CLIC is comparable to that of state-of-the-art supervised methods. In addition, we establish the pipelines that can apply CLIC to computer vision tasks to effectively improve their performance.