MedFLIP: Medical Vision-and-Language Self-supervised Fast Pre-Training with Masked Autoencoder

Within the domain of medical analysis, extensive research has explored the potential of mutual learning between Masked Autoencoders(MAEs) and multimodal data. However, the impact of MAEs on intermodality remains a key challenge. We introduce MedFLIP, a Fast Language-Image Pre-training method for Medical analysis. We explore MAEs for zero-shot learning with crossed domains, which enhances the model ability to learn from limited data, a common scenario in medical diagnostics. We verify that masking an image does not affect intermodal learning. Furthermore, we propose the SVD loss to enhance the representation learning for characteristics of medical images, aiming to improve classification accuracy by leveraging the structural intricacies of such data. Lastly, we validate using language will improve the zero-shot performance for the medical image analysis. MedFLIP scaling of the masking process marks an advancement in the field, offering a pathway to rapid and precise medical image analysis without the traditional computational bottlenecks. Through experiments and validation, MedFLIP demonstrates efficient performance improvements, setting an explored standard for future research and application in medical diagnostics.

SnapNTell: Enhancing Entity-Centric Visual Question Answering with Retrieval Augmented Multimodal LLM

Vision-extended LLMs have made significant strides in Visual Question Answering (VQA). Despite these advancements, VLLMs still encounter substantial difficulties in handling queries involving long-tail entities, with a tendency to produce erroneous or hallucinated responses. In this work, we introduce a novel evaluative benchmark named \textbf{SnapNTell}, specifically tailored for entity-centric VQA. This task aims to test the models' capabilities in identifying entities and providing detailed, entity-specific knowledge. We have developed the \textbf{SnapNTell Dataset}, distinct from traditional VQA datasets: (1) It encompasses a wide range of categorized entities, each represented by images and explicitly named in the answers; (2) It features QA pairs that require extensive knowledge for accurate responses. The dataset is organized into 22 major categories, containing 7,568 unique entities in total. For each entity, we curated 10 illustrative images and crafted 10 knowledge-intensive QA pairs. To address this novel task, we devised a scalable, efficient, and transparent retrieval-augmented multimodal LLM. Our approach markedly outperforms existing methods on the SnapNTell dataset, achieving a 66.5\% improvement in the BELURT score. We will soon make the dataset and the source code publicly accessible.

ImgTrojan: Jailbreaking Vision-Language Models with ONE Image

There has been an increasing interest in the alignment of large language models (LLMs) with human values. However, the safety issues of their integration with a vision module, or vision language models (VLMs), remain relatively underexplored. In this paper, we propose a novel jailbreaking attack against VLMs, aiming to bypass their safety barrier when a user inputs harmful instructions. A scenario where our poisoned (image, text) data pairs are included in the training data is assumed. By replacing the original textual captions with malicious jailbreak prompts, our method can perform jailbreak attacks with the poisoned images. Moreover, we analyze the effect of poison ratios and positions of trainable parameters on our attack's success rate. For evaluation, we design two metrics to quantify the success rate and the stealthiness of our attack. Together with a list of curated harmful instructions, a benchmark for measuring attack efficacy is provided. We demonstrate the efficacy of our attack by comparing it with baseline methods.

Multimodal ArXiv: A Dataset for Improving Scientific Comprehension of Large Vision-Language Models

Large vision-language models (LVLMs), exemplified by GPT-4V, excel across diverse tasks involving concrete images from natural scenes. However, their ability to interpret abstract figures, such as geometry shapes and scientific plots, remains limited due to a scarcity of training datasets in scientific domains. To fill this gap, we introduce Multimodal ArXiv, consisting of ArXivCap and ArXivQA, for enhancing LVLMs scientific comprehension. ArXivCap is a figure-caption dataset comprising 6.4M images and 3.9M captions sourced from 572K ArXiv papers spanning various scientific domains. Drawing from ArXivCap, we introduce ArXivQA, a question-answering dataset generated by prompting GPT-4V based on scientific figures. ArXivQA greatly enhances LVLMs' mathematical reasoning capabilities, achieving a 10.4% absolute accuracy gain on a multimodal mathematical reasoning benchmark. Furthermore, employing ArXivCap, we devise four vision-to-text tasks for benchmarking LVLMs. Evaluation results with state-of-the-art LVLMs underscore their struggle with the nuanced semantics of academic figures, with domain-specific training yielding substantial performance gains. Our error analysis uncovers misinterpretations of visual context, recognition errors, and the production of overly simplified captions by current LVLMs, shedding light on future improvements.

TempCompass: Do Video LLMs Really Understand Videos?

Recently, there is a surge in interest surrounding video large language models (Video LLMs). However, existing benchmarks fail to provide a comprehensive feedback on the temporal perception ability of Video LLMs. On the one hand, most of them are unable to distinguish between different temporal aspects (e.g., speed, direction) and thus cannot reflect the nuanced performance on these specific aspects. On the other hand, they are limited in the diversity of task formats (e.g., only multi-choice QA), which hinders the understanding of how temporal perception performance may vary across different types of tasks. Motivated by these two problems, we propose the \textbf{TempCompass} benchmark, which introduces a diversity of temporal aspects and task formats. To collect high-quality test data, we devise two novel strategies: (1) In video collection, we construct conflicting videos that share the same static content but differ in a specific temporal aspect, which prevents Video LLMs from leveraging single-frame bias or language priors. (2) To collect the task instructions, we propose a paradigm where humans first annotate meta-information for a video and then an LLM generates the instruction. We also design an LLM-based approach to automatically and accurately evaluate the responses from Video LLMs. Based on TempCompass, we comprehensively evaluate 8 state-of-the-art (SOTA) Video LLMs and 3 Image LLMs, and reveal the discerning fact that these models exhibit notably poor temporal perception ability. Our data will be available at \url{https://github.com/llyx97/TempCompass}.

Hire a Linguist!: Learning Endangered Languages with In-Context Linguistic Descriptions

How can large language models (LLMs) process and translate endangered languages? Many languages lack a large corpus to train a decent LLM; therefore existing LLMs rarely perform well in unseen, endangered languages. On the contrary, we observe that 2000 endangered languages, though without a large corpus, have a grammar book or a dictionary. We propose LINGOLLM, a training-free approach to enable an LLM to process unseen languages that hardly occur in its pre-training. Our key insight is to demonstrate linguistic knowledge of an unseen language in an LLM's prompt, including a dictionary, a grammar book, and morphologically analyzed input text. We implement LINGOLLM on top of two models, GPT-4 and Mixtral, and evaluate their performance on 5 tasks across 8 endangered or low-resource languages. Our results show that LINGOLLM elevates translation capability from GPT-4's 0 to 10.5 BLEU for 10 language directions. Our findings demonstrate the tremendous value of linguistic knowledge in the age of LLMs for endangered languages. Our data, code, and model generations can be found at https://github.com/LLiLab/llm4endangeredlang.

Structure-Based Drug Design via 3D Molecular Generative Pre-training and Sampling

Structure-based drug design aims at generating high affinity ligands with prior knowledge of 3D target structures. Existing methods either use conditional generative model to learn the distribution of 3D ligands given target binding sites, or iteratively modify molecules to optimize a structure-based activity estimator. The former is highly constrained by data quantity and quality, which leaves optimization-based approaches more promising in practical scenario. However, existing optimization-based approaches choose to edit molecules in 2D space, and use molecular docking to estimate the activity using docking predicted 3D target-ligand complexes. The misalignment between the action space and the objective hinders the performance of these models, especially for those employ deep learning for acceleration. In this work, we propose MolEdit3D to combine 3D molecular generation with optimization frameworks. We develop a novel 3D graph editing model to generate molecules using fragments, and pre-train this model on abundant 3D ligands for learning target-independent properties. Then we employ a target-guided self-learning strategy to improve target-related properties using self-sampled molecules. MolEdit3D achieves state-of-the-art performance on majority of the evaluation metrics, and demonstrate strong capability of capturing both target-dependent and -independent properties.

Where It Really Matters: Few-Shot Environmental Conservation Media Monitoring for Low-Resource Languages

Environmental conservation organizations routinely monitor news content on conservation in protected areas to maintain situational awareness of developments that can have an environmental impact. Existing automated media monitoring systems require large amounts of data labeled by domain experts, which is only feasible at scale for high-resource languages like English. However, such tools are most needed in the global south where news of interest is mainly in local low-resource languages, and far fewer experts are available to annotate datasets sustainably. In this paper, we propose NewsSerow, a method to automatically recognize environmental conservation content in low-resource languages. NewsSerow is a pipeline of summarization, in-context few-shot classification, and self-reflection using large language models (LLMs). Using at most 10 demonstration example news articles in Nepali, NewsSerow significantly outperforms other few-shot methods and achieves comparable performance with models fully fine-tuned using thousands of examples. The World Wide Fund for Nature (WWF) has deployed NewsSerow for media monitoring in Nepal, significantly reducing their operational burden, and ensuring that AI tools for conservation actually reach the communities that need them the most. NewsSerow has also been deployed for countries with other languages like Colombia.

Perils of Self-Feedback: Self-Bias Amplifies in Large Language Models

Recent studies show that self-feedback improves large language models (LLMs) on certain tasks while worsens other tasks. We discovered that such a contrary is due to LLM's bias towards their own output. In this paper, we formally define LLM's self-bias -- the tendency to favor its own generation -- using two statistics. We analyze six LLMs on translation, constrained text generation, and mathematical reasoning tasks. We find that self-bias is prevalent in all examined LLMs across multiple languages and tasks. Our analysis reveals that while the self-refine pipeline improves the fluency and understandability of model outputs, it further amplifies self-bias. To mitigate such biases, we discover that larger model size and external feedback with accurate assessment can significantly reduce bias in the self-refine pipeline, leading to actual performance improvement in downstream tasks.

DE-COP: Detecting Copyrighted Content in Language Models Training Data

How can we detect if copyrighted content was used in the training process of a language model, considering that the training data is typically undisclosed? We are motivated by the premise that a language model is likely to identify verbatim excerpts from its training text. We propose DE-COP, a method to determine whether a piece of copyrighted content was included in training. DE-COP's core approach is to probe an LLM with multiple-choice questions, whose options include both verbatim text and their paraphrases. We construct BookTection, a benchmark with excerpts from 165 books published prior and subsequent to a model's training cutoff, along with their paraphrases. Our experiments show that DE-COP surpasses the prior best method by 9.6% in detection performance (AUC) on models with logits available. Moreover, DE-COP also achieves an average accuracy of 72% for detecting suspect books on fully black-box models where prior methods give $\approx$ 4% accuracy. Our code and datasets are available at https://github.com/avduarte333/DE-COP_Method