A Survey on Multilingual Large Language Models: Corpora, Alignment, and Bias

Based on the foundation of Large Language Models (LLMs), Multilingual Large Language Models (MLLMs) have been developed to address the challenges of multilingual natural language processing tasks, hoping to achieve knowledge transfer from high-resource to low-resource languages. However, significant limitations and challenges still exist, such as language imbalance, multilingual alignment, and inherent bias. In this paper, we aim to provide a comprehensive analysis of MLLMs, delving deeply into discussions surrounding these critical issues. First of all, we start by presenting an overview of MLLMs, covering their evolution, key techniques, and multilingual capacities. Secondly, we explore widely utilized multilingual corpora for MLLMs' training and multilingual datasets oriented for downstream tasks that are crucial for enhancing the cross-lingual capability of MLLMs. Thirdly, we survey the existing studies on multilingual representations and investigate whether the current MLLMs can learn a universal language representation. Fourthly, we discuss bias on MLLMs including its category and evaluation metrics, and summarize the existing debiasing techniques. Finally, we discuss existing challenges and point out promising research directions. By demonstrating these aspects, this paper aims to facilitate a deeper understanding of MLLMs and their potentiality in various domains.

Using Whole Slide Image Representations from Self-Supervised Contrastive Learning for Melanoma Concordance Regression

Although melanoma occurs more rarely than several other skin cancers, patients' long term survival rate is extremely low if the diagnosis is missed. Diagnosis is complicated by a high discordance rate among pathologists when distinguishing between melanoma and benign melanocytic lesions. A tool that provides potential concordance information to healthcare providers could help inform diagnostic, prognostic, and therapeutic decision-making for challenging melanoma cases. We present a melanoma concordance regression deep learning model capable of predicting the concordance rate of invasive melanoma or melanoma in-situ from digitized Whole Slide Images (WSIs). The salient features corresponding to melanoma concordance were learned in a self-supervised manner with the contrastive learning method, SimCLR. We trained a SimCLR feature extractor with 83,356 WSI tiles randomly sampled from 10,895 specimens originating from four distinct pathology labs. We trained a separate melanoma concordance regression model on 990 specimens with available concordance ground truth annotations from three pathology labs and tested the model on 211 specimens. We achieved a Root Mean Squared Error (RMSE) of 0.28 +/- 0.01 on the test set. We also investigated the performance of using the predicted concordance rate as a malignancy classifier, and achieved a precision and recall of 0.85 +/- 0.05 and 0.61 +/- 0.06, respectively, on the test set. These results are an important first step for building an artificial intelligence (AI) system capable of predicting the results of consulting a panel of experts and delivering a score based on the degree to which the experts would agree on a particular diagnosis. Such a system could be used to suggest additional testing or other action such as ordering additional stains or genetic tests.

Robust No-Regret Learning in Min-Max Stackelberg Games

The behavior of no-regret learning algorithms is well understood in two-player min-max (i.e, zero-sum) games. In this paper, we investigate the behavior of no-regret learning in min-max games with dependent strategy sets, where the strategy of the first player constrains the behavior of the second. Such games are best understood as sequential, i.e., min-max Stackelberg, games. We consider two settings, one in which only the first player chooses their actions using a no-regret algorithm while the second player best responds, and one in which both players use no-regret algorithms. For the former case, we show that no-regret dynamics converge to a Stackelberg equilibrium. For the latter case, we introduce a new type of regret, which we call Lagrangian regret, and show that if both players minimize their Lagrangian regrets, then play converges to a Stackelberg equilibrium. We then observe that online mirror descent (OMD) dynamics in these two settings correspond respectively to a known nested (i.e., sequential) gradient descent-ascent (GDA) algorithm and a new simultaneous GDA-like algorithm, thereby establishing convergence of these algorithms to Stackelberg equilibrium. Finally, we analyze the robustness of OMD dynamics to perturbations by investigating online min-max Stackelberg games. We prove that OMD dynamics are robust for a large class of online min-max games with independent strategy sets. In the dependent case, we demonstrate the robustness of OMD dynamics experimentally by simulating them in online Fisher markets, a canonical example of a min-max Stackelberg game with dependent strategy sets.

MoG-QSM: Model-based Generative Adversarial Deep Learning Network for Quantitative Susceptibility Mapping

Quantitative susceptibility mapping (QSM) estimates the underlying tissue magnetic susceptibility from the MRI gradient-echo phase signal and has demonstrated great potential in quantifying tissue susceptibility in various brain diseases. However, the intrinsic ill-posed inverse problem relating the tissue phase to the underlying susceptibility distribution affects the accuracy for quantifying tissue susceptibility. The resulting susceptibility map is known to suffer from noise amplification and streaking artifacts. To address these challenges, we propose a model-based framework that permeates benefits from generative adversarial networks to train a regularization term that contains prior information to constrain the solution of the inverse problem, referred to as MoG-QSM. A residual network leveraging a mixture of least-squares (LS) GAN and the L1 cost was trained as the generator to learn the prior information in susceptibility maps. A multilayer convolutional neural network was jointly trained to discriminate the quality of output images. MoG-QSM generates highly accurate susceptibility maps from single orientation phase maps. Quantitative evaluation parameters were compared with recently developed deep learning QSM methods and the results showed MoG-QSM achieves the best performance. Furthermore, a higher intraclass correlation coefficient (ICC) was obtained from MoG-QSM maps of the traveling subjects, demonstrating its potential for future applications, such as large cohorts of multi-center studies. MoG-QSM is also helpful for reliable longitudinal measurement of susceptibility time courses, enabling more precise monitoring for metal ion accumulation in neurodegenerative disorders.

Learning unbiased zero-shot semantic segmentation networks via transductive transfer

Semantic segmentation, which aims to acquire a detailed understanding of images, is an essential issue in computer vision. However, in practical scenarios, new categories that are different from the categories in training usually appear. Since it is impractical to collect labeled data for all categories, how to conduct zero-shot learning in semantic segmentation establishes an important problem. Although the attribute embedding of categories can promote effective knowledge transfer across different categories, the prediction of segmentation network reveals obvious bias to seen categories. In this paper, we propose an easy-to-implement transductive approach to alleviate the prediction bias in zero-shot semantic segmentation. Our method assumes that both the source images with full pixel-level labels and unlabeled target images are available during training. To be specific, the source images are used to learn the relationship between visual images and semantic embeddings, while the target images are used to alleviate the prediction bias towards seen categories. We conduct comprehensive experiments on diverse split s of the PASCAL dataset. The experimental results clearly demonstrate the effectiveness of our method.