Oscillating Dispersion for Maximal Light-throughput Spectral Imaging

Existing computational spectral imaging systems typically rely on coded aperture and beam splitters that block a substantial fraction of incident light, degrading reconstruction quality under light-starved conditions. To address this limitation, we develop the Oscillating Dispersion Imaging Spectrometer (ODIS), which for the first time achieves near-full light throughput by axially translating a disperser between the conjugate image plane and a defocused position, sequentially capturing a panchromatic (PAN) image and a dispersed measurement along a single optical path. We further propose a PAN-guided Dispersion-Aware Deep Unfolding Network (PDAUN) that recovers high-fidelity spectral information from maskless dispersion under PAN structural guidance. Its data-fidelity step derives an FFT-Woodbury preconditioned solver by exploiting the cyclic-convolution property of the ODIS forward model, while a Dispersion-Aware Deformable Convolution module (DADC) corrects sub-pixel spectral misalignment using PAN features. Experiments show state-of-the-art performance on standard benchmarks, and cross-system comparisons confirm that ODIS yields decisive gains under low illumination. High-fidelity reconstruction is validated on a physical prototype.

Multiscale Structure-Guided Latent Diffusion for Multimodal MRI Translation

Although diffusion models have achieved remarkable progress in multi-modal magnetic resonance imaging (MRI) translation tasks, existing methods still tend to suffer from anatomical inconsistencies or degraded texture details when handling arbitrary missing-modality scenarios. To address these issues, we propose a latent diffusion-based multi-modal MRI translation framework, termed MSG-LDM. By leveraging the available modalities, the proposed method infers complete structural information, which preserves reliable boundary details. Specifically, we introduce a style--structure disentanglement mechanism in the latent space, which explicitly separates modality-specific style features from shared structural representations, and jointly models low-frequency anatomical layouts and high-frequency boundary details in a multi-scale feature space. During the structure disentanglement stage, high-frequency structural information is explicitly incorporated to enhance feature representations, guiding the model to focus on fine-grained structural cues while learning modality-invariant low-frequency anatomical representations. Furthermore, to reduce interference from modality-specific styles and improve the stability of structure representations, we design a style consistency loss and a structure-aware loss. Extensive experiments on the BraTS2020 and WMH datasets demonstrate that the proposed method outperforms existing MRI synthesis approaches, particularly in reconstructing complete structures. The source code is publicly available at https://github.com/ziyi-start/MSG-LDM.

MVHOI: Bridge Multi-view Condition to Complex Human-Object Interaction Video Reenactment via 3D Foundation Model

Human-Object Interaction (HOI) video reenactment with realistic motion remains a frontier in expressive digital human creation. Existing approaches primarily handle simple image-plane motion (e.g., in-plane translations), struggling with complex non-planar manipulations like out-of-plane reorientation. In this paper, we propose MVHOI, a two-stage HOI video reenactment framework that bridges multi-view reference conditions and video foundation models via a 3D Foundation Model (3DFM). The 3DFM first produces view-consistent object priors conditioned on implicit motion dynamics across novel viewpoints. A controllable video generation model then synthesizes high-fidelity object texture by incorporating multi-view reference images, ensuring appearance consistency via a reasonable retrieval mechanism. By enabling these two stages to mutually reinforce one another during the inference phase, our framework shows superior performance in generating long-duration HOI videos with intricate object manipulations. Extensive experiments show substantial improvements over prior approaches, especially for HOI with complex 3D object manipulations.

Segmentation-before-Staining Improves Structural Fidelity in Virtual IHC-to-Multiplex IF Translation

Multiplex immunofluorescence (mIF) enables simultaneous single-cell quantification of multiple biomarkers within intact tissue architecture, yet its high reagent cost, multi-round staining protocols, and need for specialized imaging platforms limit routine clinical adoption. Virtual staining can synthesize mIF channels from widely available brightfield immunohistochemistry (IHC), but current translators optimize pixel-level fidelity without explicitly constraining nuclear morphology. In pathology, this gap is clinically consequential: subtle distortions in nuclei count, shape, or spatial arrangement propagate directly to quantification endpoints such as the Ki67 proliferation index, where errors of a few percent can shift treatment-relevant risk categories. This work introduces a supervision-free, architecture-agnostic conditioning strategy that injects a continuous cell probability map from a pretrained nuclei segmentation foundation model as an explicit input prior, together with a variance-preserving regularization term that matches local intensity statistics to maintain cell-level heterogeneity in synthesized fluorescence channels. The soft prior retains gradient-level boundary information lost by binary thresholding, providing a richer conditioning signal without task-specific tuning. Controlled experiments across Pix2Pix with U-Net and ResNet generators, deterministic regression U-Net, and conditional diffusion on two independent datasets demonstrate consistent improvements in nuclei count fidelity and perceptual quality, as the sole modifications. Code will be made publicly available upon acceptance.

EgoForge: Goal-Directed Egocentric World Simulator

Generative world models have shown promise for simulating dynamic environments, yet egocentric video remains challenging due to rapid viewpoint changes, frequent hand-object interactions, and goal-directed procedures whose evolution depends on latent human intent. Existing approaches either focus on hand-centric instructional synthesis with limited scene evolution, perform static view translation without modeling action dynamics, or rely on dense supervision, such as camera trajectories, long video prefixes, synchronized multicamera capture, etc. In this work, we introduce EgoForge, an egocentric goal-directed world simulator that generates coherent, first-person video rollouts from minimal static inputs: a single egocentric image, a high-level instruction, and an optional auxiliary exocentric view. To improve intent alignment and temporal consistency, we propose VideoDiffusionNFT, a trajectory-level reward-guided refinement that optimizes goal completion, temporal causality, scene consistency, and perceptual fidelity during diffusion sampling. Extensive experiments show EgoForge achieves consistent gains in semantic alignment, geometric stability, and motion fidelity over strong baselines, and robust performance in real-world smart-glasses experiments.

BridgeDiff: Bridging Human Observations and Flat-Garment Synthesis for Virtual Try-Off

Virtual try-off (VTOFF) aims to recover canonical flat-garment representations from images of dressed persons for standardized display and downstream virtual try-on. Prior methods often treat VTOFF as direct image translation driven by local masks or text-only prompts, overlooking the gap between on-body appearances and flat layouts. This gap frequently leads to inconsistent completion in unobserved regions and unstable garment structure. We propose BridgeDiff, a diffusion-based framework that explicitly bridges human-centric observations and flat-garment synthesis through two complementary components. First, the Garment Condition Bridge Module (GCBM) builds a garment-cue representation that captures global appearance and semantic identity, enabling robust inference of continuous details under partial visibility. Second, the Flat Structure Constraint Module (FSCM) injects explicit flat-garment structural priors via Flat-Constraint Attention (FC-Attention) at selected denoising stages, improving structural stability beyond text-only conditioning. Extensive experiments on standard VTOFF benchmarks show that BridgeDiff achieves state-of-the-art performance, producing higher-quality flat-garment reconstructions while preserving fine-grained appearance and structural integrity.

R&D: Balancing Reliability and Diversity in Synthetic Data Augmentation for Semantic Segmentation

Collecting and annotating datasets for pixel-level semantic segmentation tasks are highly labor-intensive. Data augmentation provides a viable solution by enhancing model generalization without additional real-world data collection. Traditional augmentation techniques, such as translation, scaling, and color transformations, create geometric variations but fail to generate new structures. While generative models have been employed to extend semantic information of datasets, they often struggle to maintain consistency between the original and generated images, particularly for pixel-level tasks. In this work, we propose a novel synthetic data augmentation pipeline that integrates controllable diffusion models. Our approach balances diversity and reliability data, effectively bridging the gap between synthetic and real data. We utilize class-aware prompting and visual prior blending to improve image quality further, ensuring precise alignment with segmentation labels. By evaluating benchmark datasets such as PASCAL VOC and BDD100K, we demonstrate that our method significantly enhances semantic segmentation performance, especially in data-scarce scenarios, while improving model robustness in real-world applications. Our code is available at \href{https://github.com/chequanghuy/Enhanced-Generative-Data-Augmentation-for-Semantic-Segmentation-via-Stronger-Guidance}{https://github.com/chequanghuy/Enhanced-Generative-Data-Augmentation-for-Semantic-Segmentation-via-Stronger-Guidance}.

Universal Skeleton Understanding via Differentiable Rendering and MLLMs

Multimodal large language models (MLLMs) exhibit strong visual-language reasoning, yet remain confined to their native modalities and cannot directly process structured, non-visual data such as human skeletons. Existing methods either compress skeleton dynamics into lossy feature vectors for text alignment, or quantize motion into discrete tokens that generalize poorly across heterogeneous skeleton formats. We present SkeletonLLM, which achieves universal skeleton understanding by translating arbitrary skeleton sequences into the MLLM's native visual modality. At its core is DrAction, a differentiable, format-agnostic renderer that converts skeletal kinematics into compact image sequences. Because the pipeline is end-to-end differentiable, MLLM gradients can directly guide the rendering to produce task-informative visual tokens. To further enhance reasoning capabilities, we introduce a cooperative training strategy: Causal Reasoning Distillation transfers structured, step-by-step reasoning from a teacher model, while Discriminative Finetuning sharpens decision boundaries between confusable actions. SkeletonLLM demonstrates strong generalization on diverse tasks including recognition, captioning, reasoning, and cross-format transfer -- suggesting a viable path for applying MLLMs to non-native modalities. Code will be released upon acceptance.

A Systematic Benchmark of GAN Architectures for MRI-to-CT Synthesis

The translation from Magnetic resonance imaging (MRI) to Computed tomography (CT) has been proposed as an effective solution to facilitate MRI-only clinical workflows while limiting exposure to ionizing radiation. Although numerous Generative Adversarial Network (GAN) architectures have been proposed for MRI-to-CT translation, systematic and fair comparisons across heterogeneous models remain limited. We present a comprehensive benchmark of ten GAN architectures evaluated on the SynthRAD2025 dataset across three anatomical districts (abdomen, thorax, head-and-neck). All models were trained under a unified validation protocol with identical preprocessing and optimization settings. Performance was assessed using complementary metrics capturing voxel-wise accuracy, structural fidelity, perceptual quality, and distribution-level realism, alongside an analysis of computational complexity. Supervised Paired models consistently outperformed Unpaired approaches, confirming the importance of voxel-wise supervision. Pix2Pix achieved the most balanced performance across districts while maintaining a favorable quality-to-complexity trade-off. Multi-district training improved structural robustness, whereas intra-district training maximized voxel-wise fidelity. This benchmark provides quantitative and computational guidance for model selection in MRI-only radiotherapy workflows and establishes a reproducible framework for future comparative studies. To ensure the reproducibility of our experiments we make our code public, together with the overall results, at the following link:https://github.com/arco-group/MRI_TO_CT.git

When Minor Edits Matter: LLM-Driven Prompt Attack for Medical VLM Robustness in Ultrasound

Ultrasound is widely used in clinical practice due to its portability, cost-effectiveness, safety, and real-time imaging capabilities. However, image acquisition and interpretation remain highly operator dependent, motivating the development of robust AI-assisted analysis methods. Vision-language models (VLMs) have recently demonstrated strong multimodal reasoning capabilities and competitive performance in medical image analysis, including ultrasound. However, emerging evidence highlights significant concerns about their trustworthiness. In particular, adversarial robustness is critical because Med-VLMs operate via natural-language instructions, rendering prompt formulation a realistic and practically exploitable point of vulnerability. Small variations (typos, shorthand, underspecified requests, or ambiguous wording) can meaningfully shift model outputs. We propose a scalable adversarial evaluation framework that leverages a large language model (LLM) to generate clinically plausible adversarial prompt variants via "humanized" rewrites and minimal edits that mimic routine clinical communication. Using ultrasound multiple-choice question answering benchmarks, we systematically assess the vulnerability of SOTA Med-VLMs to these attacks, examine how attacker LLM capacity influences attack success, analyze the relationship between attack success and model confidence, and identify consistent failure patterns across models. Our results highlight realistic robustness gaps that must be addressed for safe clinical translation. Code will be released publicly following the review process.