This paper proposes an information-theoretic framework for analyzing the theoretical limits of pool-based active learning (AL), in which a subset of instances is selectively labeled. The proposed framework reformulates pool-based AL as a noisy lossy compression problem by mapping pool observations to noisy symbol observations, data selection to compression, and learning to decoding. This correspondence enables a unified information-theoretic analysis of data selection and learning in pool-based AL. Applying finite blocklength analysis of noisy lossy compression, we derive information-theoretic lower bounds on label complexity and generalization error that serve as theoretical limits for a given learning algorithm under its associated optimal data selection strategy. Specifically, our bounds include terms that reflect overfitting induced by the learning algorithm and the discrepancy between its inductive bias and the target task, and are closely related to established information-theoretic bounds and stability theory, which have not been previously applied to the analysis of pool-based AL. These properties yield a new theoretical perspective on pool-based AL.
Automated detection of electron dense deposits (EDD) in glomerular disease is hindered by the scarcity of high-quality labeled data. While crowdsourcing reduces annotation cost, it introduces label noise. We propose an active label cleaning method to efficiently denoise crowdsourced datasets. Our approach uses active learning to select the most valuable noisy samples for expert re-annotation, building high-accuracy cleaning models. A Label Selection Module leverages discrepancies between crowdsourced labels and model predictions for both sample selection and instance-level noise grading. Experiments show our method achieves 67.18% AP\textsubscript{50} on a private dataset, an 18.83% improvement over training on noisy labels. This performance reaches 95.79% of that with full expert annotation while reducing annotation cost by 73.30%. The method provides a practical, cost-effective solution for developing reliable medical AI with limited expert resources.
Active inference (AIF) unifies exploration and exploitation by minimizing the Expected Free Energy (EFE), balancing epistemic value (information gain) and pragmatic value (task performance) through a curiosity coefficient. Yet it has been unclear when this balance yields both coherent learning and efficient decision-making: insufficient curiosity can drive myopic exploitation and prevent uncertainty resolution, while excessive curiosity can induce unnecessary exploration and regret. We establish the first theoretical guarantee for EFE-minimizing agents, showing that a single requirement--sufficient curiosity--simultaneously ensures self-consistent learning (Bayesian posterior consistency) and no-regret optimization (bounded cumulative regret). Our analysis characterizes how this mechanism depends on initial uncertainty, identifiability, and objective alignment, thereby connecting AIF to classical Bayesian experimental design and Bayesian optimization within one theoretical framework. We further translate these theories into practical design guidelines for tuning the epistemic-pragmatic trade-off in hybrid learning-optimization problems, validated through real-world experiments.
Multimodal Large Language Models (MLLMs) have recently been applied to universal multimodal retrieval, where Chain-of-Thought (CoT) reasoning improves candidate reranking. However, existing approaches remain largely language-driven, relying on static visual encodings and lacking the ability to actively verify fine-grained visual evidence, which often leads to speculative reasoning in visually ambiguous cases. We propose V-Retrver, an evidence-driven retrieval framework that reformulates multimodal retrieval as an agentic reasoning process grounded in visual inspection. V-Retrver enables an MLLM to selectively acquire visual evidence during reasoning via external visual tools, performing a multimodal interleaved reasoning process that alternates between hypothesis generation and targeted visual verification.To train such an evidence-gathering retrieval agent, we adopt a curriculum-based learning strategy combining supervised reasoning activation, rejection-based refinement, and reinforcement learning with an evidence-aligned objective. Experiments across multiple multimodal retrieval benchmarks demonstrate consistent improvements in retrieval accuracy (with 23.0% improvements on average), perception-driven reasoning reliability, and generalization.
Continual learning (or class incremental learning) is a realistic learning scenario for computer vision systems, where deep neural networks are trained on episodic data, and the data from previous episodes are generally inaccessible to the model. Existing research in this domain has primarily focused on avoiding catastrophic forgetting, which occurs due to the continuously changing class distributions in each episode and the inaccessibility of the data from previous episodes. However, these methods assume that all the training samples in every episode are annotated; this not only incurs a huge annotation cost, but also results in a wastage of annotation effort, since most of the samples in a given episode will not be accessible to the model in subsequent episodes. Active learning algorithms identify the salient and informative samples from large amounts of unlabeled data and are instrumental in reducing the human annotation effort in inducing a deep neural network. In this paper, we propose ACIL, a novel active learning framework for class incremental learning settings. We exploit a criterion based on uncertainty and diversity to identify the exemplar samples that need to be annotated in each episode, and will be appended to the data in the next episode. Such a framework can drastically reduce annotation cost and can also avoid catastrophic forgetting. Our extensive empirical analyses on several vision datasets corroborate the promise and potential of our framework against relevant baselines.
Systematic literature reviews (SLRs) are fundamental to evidence-based research, but manual screening is an increasing bottleneck as scientific output grows. Screening features low prevalence of relevant studies and scarce, costly expert decisions. Traditional active learning (AL) systems help, yet typically rely on fixed query strategies for selecting the next unlabeled documents. These static strategies do not adapt over time and ignore the relational structure of scientific literature networks. This thesis introduces AutoDiscover, a framework that reframes AL as an online decision-making problem driven by an adaptive agent. Literature is modeled as a heterogeneous graph capturing relationships among documents, authors, and metadata. A Heterogeneous Graph Attention Network (HAN) learns node representations, which a Discounted Thompson Sampling (DTS) agent uses to dynamically manage a portfolio of query strategies. With real-time human-in-the-loop labels, the agent balances exploration and exploitation under non-stationary review dynamics, where strategy utility changes over time. On the 26-dataset SYNERGY benchmark, AutoDiscover achieves higher screening efficiency than static AL baselines. Crucially, the agent mitigates cold start by bootstrapping discovery from minimal initial labels where static approaches fail. We also introduce TS-Insight, an open-source visual analytics dashboard to interpret, verify, and diagnose the agent's decisions. Together, these contributions accelerate SLR screening under scarce expert labels and low prevalence of relevant studies.
Retinopathy of Prematurity (ROP) is among the major causes of preventable childhood blindness. Automated screening remains challenging, primarily due to limited data availability and the complex condition involving both structural staging and microvascular abnormalities. Current deep learning models depend heavily on large private datasets and passive multimodal fusion, which commonly fail to generalize on small, imbalanced public cohorts. We thus propose the Context-Aware Asymmetric Ensemble Model (CAA Ensemble) that simulates clinical reasoning through two specialized streams. First, the Multi-Scale Active Query Network (MS-AQNet) serves as a structure specialist, utilizing clinical contexts as dynamic query vectors to spatially control visual feature extraction for localization of the fibrovascular ridge. Secondly, VascuMIL encodes Vascular Topology Maps (VMAP) within a gated Multiple Instance Learning (MIL) network to precisely identify vascular tortuosity. A synergistic meta-learner ensembles these orthogonal signals to resolve diagnostic discordance across multiple objectives. Tested on a highly imbalanced cohort of 188 infants (6,004 images), the framework attained State-of-the-Art performance on two distinct clinical tasks: achieving a Macro F1-Score of 0.93 for Broad ROP staging and an AUC of 0.996 for Plus Disease detection. Crucially, the system features `Glass Box' transparency through counterfactual attention heatmaps and vascular threat maps, proving that clinical metadata dictates the model's visual search. Additionally, this study demonstrates that architectural inductive bias can serve as an effective bridge for the medical AI data gap.
Pre-trained vision-language models such as CLIP exhibit strong transferability, yet adapting them to downstream image classification tasks under limited annotation budgets remains challenging. In active learning settings, the model must select the most informative samples for annotation from a large pool of unlabeled data. Existing approaches typically estimate uncertainty via entropy-based criteria or representation clustering, without explicitly modeling uncertainty from the model perspective. In this work, we propose a robust uncertainty modeling framework for active CLIP adaptation based on dual-prompt tuning. We introduce two learnable prompts in the textual branch of CLIP. The positive prompt enhances the discriminability of task-specific textual embeddings corresponding to light-weight tuned visual embeddings, improving classification reliability. Meanwhile, the negative prompt is trained in an reversed manner to explicitly model the probability that the predicted label is correct, providing a principled uncertainty signal for guiding active sample selection. Extensive experiments across different fine-tuning paradigms demonstrate that our method consistently outperforms existing active learning methods under the same annotation budget.
Membership inference attacks (MIAs) aim to determine whether a sample was part of a model's training set, posing serious privacy risks for modern machine-learning systems. Existing MIAs primarily rely on static indicators, such as loss or confidence, and do not fully leverage the dynamic behavior of models when actively probed. We propose LeakBoost, a perceptual-loss-based interrogation framework that actively probes a model's internal representations to expose hidden membership signals. Given a candidate input, LeakBoost synthesizes an interrogation image by optimizing a perceptual (activation-space) objective, amplifying representational differences between members and non-members. This image is then analyzed by an off-the-shelf membership detector, without modifying the detector itself. When combined with existing membership inference methods, LeakBoost achieves substantial improvements at low false-positive rates across multiple image classification datasets and diverse neural network architectures. In particular, it raises AUC from near-chance levels (0.53-0.62) to 0.81-0.88, and increases TPR at 1 percent FPR by over an order of magnitude compared to strong baseline attacks. A detailed sensitivity analysis reveals that deeper layers and short, low-learning-rate optimization produce the strongest leakage, and that improvements concentrate in gradient-based detectors. LeakBoost thus offers a modular and computationally efficient way to assess privacy risks in white-box settings, advancing the study of dynamic membership inference.
Large Reasoning Models (LRMs) excel at complex reasoning tasks, but their efficiency is often hampered by overly verbose outputs. Prior steering methods attempt to address this issue by applying a single, global vector to hidden representations -- an approach grounded in the restrictive linear representation hypothesis. In this work, we introduce FlowSteer, a nonlinear steering method that goes beyond uniform linear shifts by learning a complete transformation between the distributions associated with verbose and concise reasoning. This transformation is learned via Flow Matching as a velocity field, enabling precise, input-dependent control over the model's reasoning process. By aligning steered representations with the distribution of concise-reasoning activations, FlowSteer yields more compact reasoning than the linear shifts. Across diverse reasoning benchmarks, FlowSteer demonstrates strong task performance and token efficiency compared to leading inference-time baselines. Our work demonstrates that modeling the full distributional transport with generative techniques offers a more effective and principled foundation for controlling LRMs.