Cyclic Learning: Bridging Image-level Labels and Nuclei Instance Segmentation

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and laborious for the high nuclei density. To alleviate the annotation burden, we seek to solve the problem through image-level weakly supervised learning, which is underexplored for nuclei instance segmentation. Compared with most existing methods using other weak annotations (scribble, point, etc.) for nuclei instance segmentation, our method is more labor-saving. The obstacle to using image-level annotations in nuclei instance segmentation is the lack of adequate location information, leading to severe nuclei omission or overlaps. In this paper, we propose a novel image-level weakly supervised method, called cyclic learning, to solve this problem. Cyclic learning comprises a front-end classification task and a back-end semi-supervised instance segmentation task to benefit from multi-task learning (MTL). We utilize a deep learning classifier with interpretability as the front-end to convert image-level labels to sets of high-confidence pseudo masks and establish a semi-supervised architecture as the back-end to conduct nuclei instance segmentation under the supervision of these pseudo masks. Most importantly, cyclic learning is designed to circularly share knowledge between the front-end classifier and the back-end semi-supervised part, which allows the whole system to fully extract the underlying information from image-level labels and converge to a better optimum. Experiments on three datasets demonstrate the good generality of our method, which outperforms other image-level weakly supervised methods for nuclei instance segmentation, and achieves comparable performance to fully-supervised methods.

Transforming Visual Scene Graphs to Image Captions

We propose to Transform Scene Graphs (TSG) into more descriptive captions. In TSG, we apply multi-head attention (MHA) to design the Graph Neural Network (GNN) for embedding scene graphs. After embedding, different graph embeddings contain diverse specific knowledge for generating the words with different part-of-speech, e.g., object/attribute embedding is good for generating nouns/adjectives. Motivated by this, we design a Mixture-of-Expert (MOE)-based decoder, where each expert is built on MHA, for discriminating the graph embeddings to generate different kinds of words. Since both the encoder and decoder are built based on the MHA, as a result, we construct a homogeneous encoder-decoder unlike the previous heterogeneous ones which usually apply Fully-Connected-based GNN and LSTM-based decoder. The homogeneous architecture enables us to unify the training configuration of the whole model instead of specifying different training strategies for diverse sub-networks as in the heterogeneous pipeline, which releases the training difficulty. Extensive experiments on the MS-COCO captioning benchmark validate the effectiveness of our TSG. The code is in: https://anonymous.4open.science/r/ACL23_TSG.

Adaptively Clustering Neighbor Elements for Image Captioning

We design a novel global-local Transformer named \textbf{Ada-ClustFormer} (\textbf{ACF}) to generate captions. We use this name since each layer of ACF can adaptively cluster input elements to carry self-attention (Self-ATT) for learning local context. Compared with other global-local Transformers which carry Self-ATT in fixed-size windows, ACF can capture varying graininess, \eg, an object may cover different numbers of grids or a phrase may contain diverse numbers of words. To build ACF, we insert a probabilistic matrix C into the Self-ATT layer. For an input sequence {{s}_1,...,{s}_N , C_{i,j} softly determines whether the sub-sequence {s_i,...,s_j} should be clustered for carrying Self-ATT. For implementation, {C}_{i,j} is calculated from the contexts of {{s}_i,...,{s}_j}, thus ACF can exploit the input itself to decide which local contexts should be learned. By using ACF to build the vision encoder and language decoder, the captioning model can automatically discover the hidden structures in both vision and language, which encourages the model to learn a unified structural space for transferring more structural commonalities. The experiment results demonstrate the effectiveness of ACF that we achieve CIDEr of 137.8, which outperforms most SOTA captioning models and achieve comparable scores compared with some BERT-based models. The code will be available in the supplementary material.