Abstract:Automated interpretation of medical images demands robust modeling of complex visual-semantic relationships while addressing annotation scarcity, label imbalance, and clinical plausibility constraints. We introduce MIRNet (Medical Image Reasoner Network), a novel framework that integrates self-supervised pre-training with constrained graph-based reasoning. Tongue image diagnosis is a particularly challenging domain that requires fine-grained visual and semantic understanding. Our approach leverages self-supervised masked autoencoder (MAE) to learn transferable visual representations from unlabeled data; employs graph attention networks (GAT) to model label correlations through expert-defined structured graphs; enforces clinical priors via constraint-aware optimization using KL divergence and regularization losses; and mitigates imbalance using asymmetric loss (ASL) and boosting ensembles. To address annotation scarcity, we also introduce TongueAtlas-4K, a comprehensive expert-curated benchmark comprising 4,000 images annotated with 22 diagnostic labels--representing the largest public dataset in tongue analysis. Validation shows our method achieves state-of-the-art performance. While optimized for tongue diagnosis, the framework readily generalizes to broader diagnostic medical imaging tasks.
Abstract:Monocular 3D Visual Grounding (Mono3DVG) is an emerging task that locates 3D objects in RGB images using text descriptions with geometric cues. However, existing methods face two key limitations. Firstly, they often over-rely on high-certainty keywords that explicitly identify the target object while neglecting critical spatial descriptions. Secondly, generalized textual features contain both 2D and 3D descriptive information, thereby capturing an additional dimension of details compared to singular 2D or 3D visual features. This characteristic leads to cross-dimensional interference when refining visual features under text guidance. To overcome these challenges, we propose Mono3DVG-EnSD, a novel framework that integrates two key components: the CLIP-Guided Lexical Certainty Adapter (CLIP-LCA) and the Dimension-Decoupled Module (D2M). The CLIP-LCA dynamically masks high-certainty keywords while retaining low-certainty implicit spatial descriptions, thereby forcing the model to develop a deeper understanding of spatial relationships in captions for object localization. Meanwhile, the D2M decouples dimension-specific (2D/3D) textual features from generalized textual features to guide corresponding visual features at same dimension, which mitigates cross-dimensional interference by ensuring dimensionally-consistent cross-modal interactions. Through comprehensive comparisons and ablation studies on the Mono3DRefer dataset, our method achieves state-of-the-art (SOTA) performance across all metrics. Notably, it improves the challenging Far(Acc@0.5) scenario by a significant +13.54%.
Abstract:With growing concerns over data privacy, researchers have started using virtual data as an alternative to sensitive real-world images for training person re-identification (Re-ID) models. However, existing virtual datasets produced by game engines still face challenges such as complex construction and poor domain generalization, making them difficult to apply in real scenarios. To address these challenges, we propose a Dual-stage Prompt-driven Privacy-preserving Paradigm (DPPP). In the first stage, we generate rich prompts incorporating multi-dimensional attributes such as pedestrian appearance, illumination, and viewpoint that drive the diffusion model to synthesize diverse data end-to-end, building a large-scale virtual dataset named GenePerson with 130,519 images of 6,641 identities. In the second stage, we propose a Prompt-driven Disentanglement Mechanism (PDM) to learn domain-invariant generalization features. With the aid of contrastive learning, we employ two textual inversion networks to map images into pseudo-words representing style and content, respectively, thereby constructing style-disentangled content prompts to guide the model in learning domain-invariant content features at the image level. Experiments demonstrate that models trained on GenePerson with PDM achieve state-of-the-art generalization performance, surpassing those on popular real and virtual Re-ID datasets.
Abstract:Deep learning has revolutionized image registration by its ability to handle diverse tasks while achieving significant speed advantages over conventional approaches. Current approaches, however, often employ globally uniform smoothness constraints that fail to accommodate the complex, regionally varying deformations characteristic of anatomical motion. To address this limitation, we propose SegReg, a Segmentation-driven Registration framework that implements anatomically adaptive regularization by exploiting region-specific deformation patterns. Our SegReg first decomposes input moving and fixed images into anatomically coherent subregions through segmentation. These localized domains are then processed by the same registration backbone to compute optimized partial deformation fields, which are subsequently integrated into a global deformation field. SegReg achieves near-perfect structural alignment (98.23% Dice on critical anatomies) using ground-truth segmentation, and outperforms existing methods by 2-12% across three clinical registration scenarios (cardiac, abdominal, and lung images) even with automatic segmentation. Our SegReg demonstrates a near-linear dependence of registration accuracy on segmentation quality, transforming the registration challenge into a segmentation problem. The source code will be released upon manuscript acceptance.
Abstract:Monocular 3D visual grounding is a novel task that aims to locate 3D objects in RGB images using text descriptions with explicit geometry information. Despite the inclusion of geometry details in the text, we observe that the text embeddings are sensitive to the magnitude of numerical values but largely ignore the associated measurement units. For example, simply equidistant mapping the length with unit "meter" to "decimeters" or "centimeters" leads to severe performance degradation, even though the physical length remains equivalent. This observation signifies the weak 3D comprehension of pre-trained language model, which generates misguiding text features to hinder 3D perception. Therefore, we propose to enhance the 3D perception of model on text embeddings and geometry features with two simple and effective methods. Firstly, we introduce a pre-processing method named 3D-text Enhancement (3DTE), which enhances the comprehension of mapping relationships between different units by augmenting the diversity of distance descriptors in text queries. Next, we propose a Text-Guided Geometry Enhancement (TGE) module to further enhance the 3D-text information by projecting the basic text features into geometrically consistent space. These 3D-enhanced text features are then leveraged to precisely guide the attention of geometry features. We evaluate the proposed method through extensive comparisons and ablation studies on the Mono3DRefer dataset. Experimental results demonstrate substantial improvements over previous methods, achieving new state-of-the-art results with a notable accuracy gain of 11.94\% in the "Far" scenario. Our code will be made publicly available.
Abstract:Jointly addressing Byzantine attacks and privacy leakage in distributed machine learning (DML) has become an important issue. A common strategy involves integrating Byzantine-resilient aggregation rules with differential privacy mechanisms. However, the incorporation of these techniques often results in a significant degradation in model accuracy. To address this issue, we propose a decentralized DML framework, named ImprovDML, that achieves high model accuracy while simultaneously ensuring privacy preservation and resilience to Byzantine attacks. The framework leverages a kind of resilient vector consensus algorithms that can compute a point within the normal (non-Byzantine) agents' convex hull for resilient aggregation at each iteration. Then, multivariate Gaussian noises are introduced to the gradients for privacy preservation. We provide convergence guarantees and derive asymptotic learning error bounds under non-convex settings, which are tighter than those reported in existing works. For the privacy analysis, we adopt the notion of concentrated geo-privacy, which quantifies privacy preservation based on the Euclidean distance between inputs. We demonstrate that it enables an improved trade-off between privacy preservation and model accuracy compared to differential privacy. Finally, numerical simulations validate our theoretical results.
Abstract:Real-world image super-resolution (Real-SR) is a challenging problem due to the complex degradation patterns in low-resolution images. Unlike approaches that assume a broadly encompassing degradation space, we focus specifically on achieving an optimal balance in how SR networks handle different degradation patterns within a fixed degradation space. We propose an improved paradigm that frames Real-SR as a data-heterogeneous multi-task learning problem, our work addresses task imbalance in the paradigm through coordinated advancements in task definition, imbalance quantification, and adaptive data rebalancing. Specifically, we introduce a novel task definition framework that segments the degradation space by setting parameter-specific boundaries for degradation operators, effectively reducing the task quantity while maintaining task discrimination. We then develop a focal loss based multi-task weighting mechanism that precisely quantifies task imbalance dynamics during model training. Furthermore, to prevent sporadic outlier samples from dominating the gradient optimization of the shared multi-task SR model, we strategically convert the quantified task imbalance into controlled data rebalancing through deliberate regulation of task-specific training volumes. Extensive quantitative and qualitative experiments demonstrate that our method achieves consistent superiority across all degradation tasks.




Abstract:Mesh reconstruction is a cornerstone process across various applications, including in-silico trials, digital twins, surgical planning, and navigation. Recent advancements in deep learning have notably enhanced mesh reconstruction speeds. Yet, traditional methods predominantly rely on deforming a standardised template mesh for individual subjects, which overlooks the unique anatomical variations between them, and may compromise the fidelity of the reconstructions. In this paper, we propose an adaptive-template-based mesh reconstruction network (ATMRN), which generates adaptive templates from the given images for the subsequent deformation, moving beyond the constraints of a singular, fixed template. Our approach, validated on cortical magnetic resonance (MR) images from the OASIS dataset, sets a new benchmark in voxel-to-cortex mesh reconstruction, achieving an average symmetric surface distance of 0.267mm across four cortical structures. Our proposed method is generic and can be easily transferred to other image modalities and anatomical structures.




Abstract:Lung cancer is a leading cause of cancer-related deaths globally. PET-CT is crucial for imaging lung tumors, providing essential metabolic and anatomical information, while it faces challenges such as poor image quality, motion artifacts, and complex tumor morphology. Deep learning-based models are expected to address these problems, however, existing small-scale and private datasets limit significant performance improvements for these methods. Hence, we introduce a large-scale PET-CT lung tumor segmentation dataset, termed PCLT20K, which comprises 21,930 pairs of PET-CT images from 605 patients. Furthermore, we propose a cross-modal interactive perception network with Mamba (CIPA) for lung tumor segmentation in PET-CT images. Specifically, we design a channel-wise rectification module (CRM) that implements a channel state space block across multi-modal features to learn correlated representations and helps filter out modality-specific noise. A dynamic cross-modality interaction module (DCIM) is designed to effectively integrate position and context information, which employs PET images to learn regional position information and serves as a bridge to assist in modeling the relationships between local features of CT images. Extensive experiments on a comprehensive benchmark demonstrate the effectiveness of our CIPA compared to the current state-of-the-art segmentation methods. We hope our research can provide more exploration opportunities for medical image segmentation. The dataset and code are available at https://github.com/mj129/CIPA.
Abstract:Multimodal 3D object detectors leverage the strengths of both geometry-aware LiDAR point clouds and semantically rich RGB images to enhance detection performance. However, the inherent heterogeneity between these modalities, including unbalanced convergence and modal misalignment, poses significant challenges. Meanwhile, the large size of the detection-oriented feature also constrains existing fusion strategies to capture long-range dependencies for the 3D detection tasks. In this work, we introduce a fast yet effective multimodal 3D object detector, incorporating our proposed Instance-level Contrastive Distillation (ICD) framework and Cross Linear Attention Fusion Module (CLFM). ICD aligns instance-level image features with LiDAR representations through object-aware contrastive distillation, ensuring fine-grained cross-modal consistency. Meanwhile, CLFM presents an efficient and scalable fusion strategy that enhances cross-modal global interactions within sizable multimodal BEV features. Extensive experiments on the KITTI and nuScenes 3D object detection benchmarks demonstrate the effectiveness of our methods. Notably, our 3D object detector outperforms state-of-the-art (SOTA) methods while achieving superior efficiency. The implementation of our method has been released as open-source at: https://github.com/nubot-nudt/ICD-Fusion.