LLM4MG: Adapting Large Language Model for Multipath Generation via Synesthesia of Machines

Based on Synesthesia of Machines (SoM), a large language model (LLM) is adapted for multipath generation (LLM4MG) for the first time. Considering a typical sixth-generation (6G) vehicle-to-infrastructure (V2I) scenario, a new multi-modal sensing-communication dataset is constructed, named SynthSoM-V2I, including channel multipath information, millimeter wave (mmWave) radar sensory data, RGB-D images, and light detection and ranging (LiDAR) point clouds. Based on the SynthSoM-V2I dataset, the proposed LLM4MG leverages Large Language Model Meta AI (LLaMA) 3.2 for multipath generation via multi-modal sensory data. The proposed LLM4MG aligns the multi-modal feature space with the LLaMA semantic space through feature extraction and fusion networks. To further achieve general knowledge transfer from the pre-trained LLaMA for multipath generation via multi-modal sensory data, the low-rank adaptation (LoRA) parameter-efficient fine-tuning and propagation-aware prompt engineering are exploited. Simulation results demonstrate that the proposed LLM4MG outperforms conventional deep learning-based methods in terms of line-of-sight (LoS)/non-LoS (NLoS) classification with accuracy of 92.76%, multipath power/delay generation precision with normalized mean square error (NMSE) of 0.099/0.032, and cross-vehicular traffic density (VTD), cross-band, and cross-scenario generalization. The utility of the proposed LLM4MG is validated by real-world generalization. The necessity of high-precision multipath generation for system design is also demonstrated by channel capacity comparison.

Multi-Modal Intelligent Channel Modeling Framework for 6G-Enabled Networked Intelligent Systems

The design and technology development of 6G-enabled networked intelligent systems needs an accurate real-time channel model as the cornerstone. However, with the new requirements of 6G-enabled networked intelligent systems, the conventional channel modeling methods face many limitations. Fortunately, the multi-modal sensors equipped on the intelligent agents bring timely opportunities, i.e., the intelligent integration and mutually beneficial mechanism between communications and multi-modal sensing could be investigated based on the artificial intelligence (AI) technologies. In this case, the mapping relationship between physical environment and electromagnetic channel could be explored via Synesthesia of Machines (SoM). This article presents a novel multi-modal intelligent channel modeling (MMICM) framework for 6G-enabled networked intelligent systems, which establishes a nonlinear model between multi-modal sensing and channel characteristics, including large-scale and small-scale channel characteristics. The architecture and features of proposed intelligent modeling framework are expounded and the key technologies involved are also analyzed. Finally, the system-engaged applications and potential research directions of MMICM framework are outlined.

Revisiting Chain-of-Thought Prompting: Zero-shot Can Be Stronger than Few-shot

In-Context Learning (ICL) is an essential emergent ability of Large Language Models (LLMs), and recent studies introduce Chain-of-Thought (CoT) to exemplars of ICL to enhance the reasoning capability, especially in mathematics tasks. However, given the continuous advancement of model capabilities, it remains unclear whether CoT exemplars still benefit recent, stronger models in such tasks. Through systematic experiments, we find that for recent strong models such as the Qwen2.5 series, adding traditional CoT exemplars does not improve reasoning performance compared to Zero-Shot CoT. Instead, their primary function is to align the output format with human expectations. We further investigate the effectiveness of enhanced CoT exemplars, constructed using answers from advanced models such as \texttt{Qwen2.5-Max} and \texttt{DeepSeek-R1}. Experimental results indicate that these enhanced exemplars still fail to improve the model's reasoning performance. Further analysis reveals that models tend to ignore the exemplars and focus primarily on the instructions, leading to no observable gain in reasoning ability. Overall, our findings highlight the limitations of the current ICL+CoT framework in mathematical reasoning, calling for a re-examination of the ICL paradigm and the definition of exemplars.

Synesthesia of Machines (SoM)-Enhanced Sub-THz ISAC Transmission for Air-Ground Network

Integrated sensing and communication (ISAC) within sub-THz frequencies is crucial for future air-ground networks, but unique propagation characteristics and hardware limitations present challenges in optimizing ISAC performance while increasing operational latency. This paper introduces a multi-modal sensing fusion framework inspired by synesthesia of machine (SoM) to enhance sub-THz ISAC transmission. By exploiting inherent degrees of freedom in sub-THz hardware and channels, the framework optimizes the radio-frequency environment. Squint-aware beam management is developed to improve air-ground network adaptability, enabling three-dimensional dynamic ISAC links. Leveraging multi-modal information, the framework enhances ISAC performance and reduces latency. Visual data rapidly localizes users and targets, while a customized multi-modal learning algorithm optimizes the hybrid precoder. A new metric provides comprehensive performance evaluation, and extensive experiments demonstrate that the proposed scheme significantly improves ISAC efficiency.

Synesthesia of Machines (SoM)-Aided Online FDD Precoding via Heterogeneous Multi-Modal Sensing: A Vertical Federated Learning Approach

This paper investigates a heterogeneous multi-vehicle, multi-modal sensing (H-MVMM) aided online precoding problem. The proposed H-MVMM scheme utilizes a vertical federated learning (VFL) framework to minimize pilot sequence length and optimize the sum rate. This offers a promising solution for reducing latency in frequency division duplexing systems. To achieve this, three preprocessing modules are designed to transform raw sensory data into informative representations relevant to precoding. The approach effectively addresses local data heterogeneity arising from diverse on-board sensor configurations through a well-structured VFL training procedure. Additionally, a label-free online model updating strategy is introduced, enabling the H-MVMM scheme to adapt its weights flexibly. This strategy features a pseudo downlink channel state information label simulator (PCSI-Simulator), which is trained using a semi-supervised learning (SSL) approach alongside an online loss function. Numerical results show that the proposed method can closely approximate the performance of traditional optimization techniques with perfect channel state information, achieving a significant 90.6\% reduction in pilot sequence length.

Foundation Model Empowered Synesthesia of Machines (SoM): AI-native Intelligent Multi-Modal Sensing-Communication Integration

To support future intelligent multifunctional sixth-generation (6G) wireless communication networks, Synesthesia of Machines (SoM) is proposed as a novel paradigm for artificial intelligence (AI)-native intelligent multi-modal sensing-communication integration. However, existing SoM system designs rely on task-specific AI models and face challenges such as scarcity of massive high-quality datasets, constrained modeling capability, poor generalization, and limited universality. Recently, foundation models (FMs) have emerged as a new deep learning paradigm and have been preliminarily applied to SoM-related tasks, but a systematic design framework is still lacking. In this paper, we for the first time present a systematic categorization of FMs for SoM system design, dividing them into general-purpose FMs, specifically large language models (LLMs), and SoM domain-specific FMs, referred to as wireless foundation models. Furthermore, we derive key characteristics of FMs in addressing existing challenges in SoM systems and propose two corresponding roadmaps, i.e., LLM-based and wireless foundation model-based design. For each roadmap, we provide a framework containing key design steps as a guiding pipeline and several representative case studies of FM-empowered SoM system design. Specifically, we propose LLM-based path loss generation (LLM4PG) and scatterer generation (LLM4SG) schemes, and wireless channel foundation model (WiCo) for SoM mechanism exploration, LLM-based wireless multi-task SoM transceiver (LLM4WM) and wireless foundation model (WiFo) for SoM-enhanced transceiver design, and wireless cooperative perception foundation model (WiPo) for SoM-enhanced cooperative perception, demonstrating the significant superiority of FMs over task-specific models. Finally, we summarize and highlight potential directions for future research.

LLM4SP: Large Language Models for Scatterer Prediction via Synesthesia of Machines

Guided by Synesthesia of Machines (SoM), the nonlinear mapping relationship between sensory and communication information serves as a powerful tool to enhance both the accuracy and generalization of vehicle-to-vehicle (V2V) multi-modal intelligent channel modeling (MMICM) in intelligent transportation systems (ITSs). To explore the general mapping relationship between physical environment and electromagnetic space, a new intelligent sensing-communication integration dataset, named V2V-M3, is constructed for multiple scenarios in V2V communications with multiple frequency bands and multiple vehicular traffic densities (VTDs). Leveraging the strong representation and cross-modal inference capabilities of large language models (LLMs), a novel LLM-based method for Scatterer Prediction (LLM4SP) from light detection and ranging (LiDAR) point clouds is developed. To address the inherent and significant differences across multi-modal data, synergistically optimized four-module architecture, i.e., preprocessor, embedding, backbone, and output modules, are designed by considering the sensing/channel characteristics and electromagnetic propagation mechanism. On the basis of cross-modal representation alignment and positional encoding, the network of LLM4SP is fine-tuned to capture the general mapping relationship between LiDAR point clouds and scatterers. Simulation results demonstrate that the proposed LLM4SP achieves superior performance in full-sample and generalization testing, significantly outperforming small models across different frequency bands, scenarios, and VTDs.

HyboWaveNet: Hyperbolic Graph Neural Networks with Multi-Scale Wavelet Transform for Protein-Protein Interaction Prediction

Protein-protein interactions (PPIs) are fundamental for deciphering cellular functions,disease pathways,and drug discovery.Although existing neural networks and machine learning methods have achieved high accuracy in PPI prediction,their black-box nature leads to a lack of causal interpretation of the prediction results and difficulty in capturing hierarchical geometries and multi-scale dynamic interaction patterns among proteins.To address these challenges, we propose HyboWaveNet,a novel deep learning framework that collaborates with hyperbolic graphical neural networks (HGNNs) and multiscale graphical wavelet transform for robust PPI prediction. Mapping protein features to Lorentz space simulates hierarchical topological relationships among biomolecules via a hyperbolic distance metric,enabling node feature representations that better fit biological a priori.HyboWaveNet inherently simulates hierarchical and scale-free biological relationships, while the integration of wavelet transforms enables adaptive extraction of local and global interaction features across different resolutions. Our framework generates node feature representations via a graph neural network under the Lorenz model and generates pairs of positive samples under multiple different views for comparative learning, followed by further feature extraction via multi-scale graph wavelet transforms to predict potential PPIs. Experiments on public datasets show that HyboWaveNet improves over both existing state-of-the-art methods. We also demonstrate through ablation experimental studies that the multi-scale graph wavelet transform module improves the predictive performance and generalization ability of HyboWaveNet. This work links geometric deep learning and signal processing to advance PPI prediction, providing a principled approach for analyzing complex biological systems

Heterogeneous network drug-target interaction prediction model based on graph wavelet transform and multi-level contrastive learning

Drug-target interaction (DTI) prediction is a core task in drug development and precision medicine in the biomedical field. However, traditional machine learning methods generally have the black box problem, which makes it difficult to reveal the deep correlation between the model decision mechanism and the interaction pattern between biological molecules. This study proposes a heterogeneous network drug target interaction prediction framework, integrating graph neural network and multi scale signal processing technology to construct a model with both efficient prediction and multi level interpretability. Its technical breakthroughs are mainly reflected in the following three dimensions:Local global feature collaborative perception module. Based on heterogeneous graph convolutional neural network (HGCN), a multi order neighbor aggregation strategy is designed.Multi scale graph signal decomposition and biological interpretation module. A deep hierarchical node feature transform (GWT) architecture is proposed.Contrastive learning combining multi dimensional perspectives and hierarchical representations. By comparing the learning models, the node representations from the two perspectives of HGCN and GWT are aligned and fused, so that the model can integrate multi dimensional information and improve the prediction robustness. Experimental results show that our framework shows excellent prediction performance on all datasets. This study provides a complete solution for drug target discovery from black box prediction to mechanism decoding, and its methodology has important reference value for modeling complex biomolecular interaction systems.

Probabilistic Uncertain Reward Model: A Natural Generalization of Bradley-Terry Reward Model

Reinforcement Learning from Human Feedback (RLHF) has emerged as a critical technique for training large language models. However, reward hacking-a phenomenon where models exploit flaws in the reward model-remains a significant barrier to achieving robust and scalable intelligence through long-term training. Existing studies have proposed uncertain reward model to address reward hacking, however, they often lack systematic or theoretical foundations, failing to model the uncertainty intrinsically emerging from preference data. In this paper, we propose the Probabilistic Uncertain Reward Model (PURM), a natural generalization of the classical Bradley-Terry reward model. PURM learns reward distributions directly from preference data and quantifies per-sample uncertainty via the average overlap area between reward distributions. To mitigate reward hacking, we further introduce an uncertainty-aware penalty into Proximal Policy Optimization (PPO), which leverages the learned uncertainty to dynamically balance reward optimization and exploration. We propose a lightweight and easy-to-use implementation of PURM. Experiments demonstrate that PURM significantly delays the onset of reward hacking while improving final reward performance, outperforming baseline methods in both stability and effectiveness.