Understanding Synergistic Interactions among Pathology Foundation Models via Adaptive Fusion

Pathology foundation models (PFMs) provide strong tile-level representations via self-supervised pre-training on large-scale pathology images. Yet, PFMs are developed under diverse and often opaque data, architecture, and objective choices, inducing latent representational biases that limit robustness and obscure what each model specialises in. We present AdaFusion, a lightweight adaptive fusion framework that integrates complementary signals from multiple frozen PFMs through (1) low-dimensional feature compression and (2) a sample-conditioned gating module that reweights model-wise (and optionally channel-wise) contributions. Beyond improving predictive accuracy, AdaFusion provides contribution-driven interpretation that offers evidence consistent with model-specific preferences and synergistic interactions across tissue phenotypes. We evaluate AdaFusion on three public benchmarks spanning treatment response prediction, prostate cancer grading, and spatial gene expression inference. AdaFusion consistently outperforms individual PFMs and other fusion baselines, while providing interpretable tissue visualisation which aligns model preferences with morphological patterns. Code is available at: https://github.com/xyx-98/PathoOracle.

Harnessing Adversarial Distillation to Customise Debiased, Disease-Specific Pathology Foundation Models for Breast Cancer

Pathology foundation models (PFMs) provide strong tissue representations and have become central to digital pathology. However, deployment in disease-specific settings is limited by 1) the high computational cost of billion-parameter PFMs and 2) distribution mismatch and non-biological bias inherited from pan-cancer, multi-centre pre-training, including site-specific signatures and imbalanced disease prevalence. These factors can encourage shortcut learning and under-emphasise subtle morphology required for reliable modelling of a specific cancer type. We present SmartStu (a Smart Student), a framework to customise compact, breast-cancer-specific PFMs via distillation whilst mitigating confounding. SmartStu distils representations from multiple teacher PFMs into a lightweight student backbone. Crucially, we introduce adversarial distillation that leverages a dedicated noise model trained to predict nuisance, edge-dominated cues on the distillation set. Using this noise model as a counterexample, the adversarial objective encourages the student to recognise, yet suppress, features predictive of nuisance targets. We further incorporate multi-teacher ensemble distillation and an auxiliary self-supervised objective with artefact injection. We validate SmartStu on three external cohorts (Yale HER2, SLN-Breast, and BRACS) with multiple tiny backbones. SmartStu yields breast-cancer-specific PFMs that are over $30\times$ smaller than general PFMs whilst largely preserving, and sometimes improving, downstream performance measured by balanced accuracy (bAcc) and AUC. Code is available at https://github.com/zwchen03/advDistall.

WildSVG: Towards Reliable SVG Generation Under Real-Word Conditions

We introduce the task of SVG extraction, which consists in translating specific visual inputs from an image into scalable vector graphics. Existing multimodal models achieve strong results when generating SVGs from clean renderings or textual descriptions, but they fall short in real-world scenarios where natural images introduce noise, clutter, and domain shifts. A central challenge in this direction is the lack of suitable benchmarks. To address this need, we introduce the WildSVG Benchmark, formed by two complementary datasets: Natural WildSVG, built from real images containing company logos paired with their SVG annotations, and Synthetic WildSVG, which blends complex SVG renderings into real scenes to simulate difficult conditions. Together, these resources provide the first foundation for systematic benchmarking SVG extraction. We benchmark state-of-the-art multimodal models and find that current approaches perform well below what is needed for reliable SVG extraction in real scenarios. Nonetheless, iterative refinement methods point to a promising path forward, and model capabilities are steadily improving

TraceTrans: Translation and Spatial Tracing for Surgical Prediction

Image-to-image translation models have achieved notable success in converting images across visual domains and are increasingly used for medical tasks such as predicting post-operative outcomes and modeling disease progression. However, most existing methods primarily aim to match the target distribution and often neglect spatial correspondences between the source and translated images. This limitation can lead to structural inconsistencies and hallucinations, undermining the reliability and interpretability of the predictions. These challenges are accentuated in clinical applications by the stringent requirement for anatomical accuracy. In this work, we present TraceTrans, a novel deformable image translation model designed for post-operative prediction that generates images aligned with the target distribution while explicitly revealing spatial correspondences with the pre-operative input. The framework employs an encoder for feature extraction and dual decoders for predicting spatial deformations and synthesizing the translated image. The predicted deformation field imposes spatial constraints on the generated output, ensuring anatomical consistency with the source. Extensive experiments on medical cosmetology and brain MRI datasets demonstrate that TraceTrans delivers accurate and interpretable post-operative predictions, highlighting its potential for reliable clinical deployment.

LimiX: Unleashing Structured-Data Modeling Capability for Generalist Intelligence

We argue that progress toward general intelligence requires complementary foundation models grounded in language, the physical world, and structured data. This report presents LimiX, the first installment of our large structured-data models (LDMs). LimiX treats structured data as a joint distribution over variables and missingness, thus capable of addressing a wide range of tabular tasks through query-based conditional prediction via a single model. LimiX is pretrained using masked joint-distribution modeling with an episodic, context-conditional objective, where the model predicts for query subsets conditioned on dataset-specific contexts, supporting rapid, training-free adaptation at inference. We evaluate LimiX across 10 large structured-data benchmarks with broad regimes of sample size, feature dimensionality, class number, categorical-to-numerical feature ratio, missingness, and sample-to-feature ratios. With a single model and a unified interface, LimiX consistently surpasses strong baselines including gradient-boosting trees, deep tabular networks, recent tabular foundation models, and automated ensembles, as shown in Figure 1 and Figure 2. The superiority holds across a wide range of tasks, such as classification, regression, missing value imputation, and data generation, often by substantial margins, while avoiding task-specific architectures or bespoke training per task. All LimiX models are publicly accessible under Apache 2.0.

AdaFusion: Prompt-Guided Inference with Adaptive Fusion of Pathology Foundation Models

Pathology foundation models (PFMs) have demonstrated strong representational capabilities through self-supervised pre-training on large-scale, unannotated histopathology image datasets. However, their diverse yet opaque pretraining contexts, shaped by both data-related and structural/training factors, introduce latent biases that hinder generalisability and transparency in downstream applications. In this paper, we propose AdaFusion, a novel prompt-guided inference framework that, to our knowledge, is among the very first to dynamically integrate complementary knowledge from multiple PFMs. Our method compresses and aligns tile-level features from diverse models and employs a lightweight attention mechanism to adaptively fuse them based on tissue phenotype context. We evaluate AdaFusion on three real-world benchmarks spanning treatment response prediction, tumour grading, and spatial gene expression inference. Our approach consistently surpasses individual PFMs across both classification and regression tasks, while offering interpretable insights into each model's biosemantic specialisation. These results highlight AdaFusion's ability to bridge heterogeneous PFMs, achieving both enhanced performance and interpretability of model-specific inductive biases.

ACMamba: Fast Unsupervised Anomaly Detection via An Asymmetrical Consensus State Space Model

Unsupervised anomaly detection in hyperspectral images (HSI), aiming to detect unknown targets from backgrounds, is challenging for earth surface monitoring. However, current studies are hindered by steep computational costs due to the high-dimensional property of HSI and dense sampling-based training paradigm, constraining their rapid deployment. Our key observation is that, during training, not all samples within the same homogeneous area are indispensable, whereas ingenious sampling can provide a powerful substitute for reducing costs. Motivated by this, we propose an Asymmetrical Consensus State Space Model (ACMamba) to significantly reduce computational costs without compromising accuracy. Specifically, we design an asymmetrical anomaly detection paradigm that utilizes region-level instances as an efficient alternative to dense pixel-level samples. In this paradigm, a low-cost Mamba-based module is introduced to discover global contextual attributes of regions that are essential for HSI reconstruction. Additionally, we develop a consensus learning strategy from the optimization perspective to simultaneously facilitate background reconstruction and anomaly compression, further alleviating the negative impact of anomaly reconstruction. Theoretical analysis and extensive experiments across eight benchmarks verify the superiority of ACMamba, demonstrating a faster speed and stronger performance over the state-of-the-art.

DiffMOD: Progressive Diffusion Point Denoising for Moving Object Detection in Remote Sensing

Moving object detection (MOD) in remote sensing is significantly challenged by low resolution, extremely small object sizes, and complex noise interference. Current deep learning-based MOD methods rely on probability density estimation, which restricts flexible information interaction between objects and across temporal frames. To flexibly capture high-order inter-object and temporal relationships, we propose a point-based MOD in remote sensing. Inspired by diffusion models, the network optimization is formulated as a progressive denoising process that iteratively recovers moving object centers from sparse noisy points. Specifically, we sample scattered features from the backbone outputs as atomic units for subsequent processing, while global feature embeddings are aggregated to compensate for the limited coverage of sparse point features. By modeling spatial relative positions and semantic affinities, Spatial Relation Aggregation Attention is designed to enable high-order interactions among point-level features for enhanced object representation. To enhance temporal consistency, the Temporal Propagation and Global Fusion module is designed, which leverages an implicit memory reasoning mechanism for robust cross-frame feature integration. To align with the progressive denoising process, we propose a progressive MinK optimal transport assignment strategy that establishes specialized learning objectives at each denoising level. Additionally, we introduce a missing loss function to counteract the clustering tendency of denoised points around salient objects. Experiments on the RsData remote sensing MOD dataset show that our MOD method based on scattered point denoising can more effectively explore potential relationships between sparse moving objects and improve the detection capability and temporal consistency.

SACB-Net: Spatial-awareness Convolutions for Medical Image Registration

Deep learning-based image registration methods have shown state-of-the-art performance and rapid inference speeds. Despite these advances, many existing approaches fall short in capturing spatially varying information in non-local regions of feature maps due to the reliance on spatially-shared convolution kernels. This limitation leads to suboptimal estimation of deformation fields. In this paper, we propose a 3D Spatial-Awareness Convolution Block (SACB) to enhance the spatial information within feature representations. Our SACB estimates the spatial clusters within feature maps by leveraging feature similarity and subsequently parameterizes the adaptive convolution kernels across diverse regions. This adaptive mechanism generates the convolution kernels (weights and biases) tailored to spatial variations, thereby enabling the network to effectively capture spatially varying information. Building on SACB, we introduce a pyramid flow estimator (named SACB-Net) that integrates SACBs to facilitate multi-scale flow composition, particularly addressing large deformations. Experimental results on the brain IXI and LPBA datasets as well as Abdomen CT datasets demonstrate the effectiveness of SACB and the superiority of SACB-Net over the state-of-the-art learning-based registration methods. The code is available at https://github.com/x-xc/SACB_Net .

MathMistake Checker: A Comprehensive Demonstration for Step-by-Step Math Problem Mistake Finding by Prompt-Guided LLMs

We propose a novel system, MathMistake Checker, designed to automate step-by-step mistake finding in mathematical problems with lengthy answers through a two-stage process. The system aims to simplify grading, increase efficiency, and enhance learning experiences from a pedagogical perspective. It integrates advanced technologies, including computer vision and the chain-of-thought capabilities of the latest large language models (LLMs). Our system supports open-ended grading without reference answers and promotes personalized learning by providing targeted feedback. We demonstrate its effectiveness across various types of math problems, such as calculation and word problems.