GMPilot: An Expert AI Agent For FDA cGMP Compliance

The pharmaceutical industry is facing challenges with quality management such as high costs of compliance, slow responses and disjointed knowledge. This paper presents GMPilot, a domain-specific AI agent that is designed to support FDA cGMP compliance. GMPilot is based on a curated knowledge base of regulations and historical inspection observations and uses Retrieval-Augmented Generation (RAG) and Reasoning-Acting (ReAct) frameworks to provide real-time and traceable decision support to the quality professionals. In a simulated inspection scenario, GMPilot shows how it can improve the responsiveness and professionalism of quality professionals by providing structured knowledge retrieval and verifiable regulatory and case-based support. Although GMPilot lacks in the aspect of regulatory scope and model interpretability, it is a viable avenue of improving quality management decision-making in the pharmaceutical sector using intelligent approaches and an example of specialized application of AI in highly regulated sectors.

MaS-VQA: A Mask-and-Select Framework for Knowledge-Based Visual Question Answering

Knowledge-based Visual Question Answering (KB-VQA) requires models to answer questions by integrating visual information with external knowledge. However, retrieved knowledge is often noisy, partially irrelevant, or misaligned with the visual content, while internal model knowledge is difficult to control and interpret. Naive aggregation of these sources limits reasoning effectiveness and reduces answer accuracy. To address this, we propose MaS-VQA, a selection-driven framework that tightly couples explicit knowledge filtering with implicit knowledge reasoning. MaS-VQA first retrieves candidate passages and applies a Mask-and-Select mechanism to jointly prune irrelevant image regions and weakly relevant knowledge fragments, producing compact, high-signal multimodal knowledge . This filtered knowledge then guides the activation of internal knowledge in a constrained semantic space, enabling complementary co-modeling of explicit and implicit knowledge for robust answer prediction. Experiments on Encyclopedic-VQA and InfoSeek demonstrate consistent performance gains across multiple MLLM backbones, and ablations verify that the selection mechanism effectively reduces noise and enhances knowledge utilization.

Vista: Scene-Aware Optimization for Streaming Video Question Answering under Post-Hoc Queries

Streaming video question answering (Streaming Video QA) poses distinct challenges for multimodal large language models (MLLMs), as video frames arrive sequentially and user queries can be issued at arbitrary time points. Existing solutions relying on fixed-size memory or naive compression often suffer from context loss or memory overflow, limiting their effectiveness in long-form, real-time scenarios. We present Vista, a novel framework for scene-aware streaming video QA that enables efficient and scalable reasoning over continuous video streams. The innovation of Vista can be summarized in three aspects: (1) scene-aware segmentation, where Vista dynamically clusters incoming frames into temporally and visually coherent scene units; (2) scene-aware compression, where each scene is compressed into a compact token representation and stored in GPU memory for efficient index-based retrieval, while full-resolution frames are offloaded to CPU memory; and (3) scene-aware recall, where relevant scenes are selectively recalled and reintegrated into the model input upon receiving a query, enabling both efficiency and completeness. Vista is model-agnostic and integrates seamlessly with a variety of vision-language backbones, enabling long-context reasoning without compromising latency or memory efficiency. Extensive experiments on StreamingBench demonstrate that Vista achieves state-of-the-art performance, establishing a strong baseline for real-world streaming video understanding.

QuantLRM: Quantization of Large Reasoning Models via Fine-Tuning Signals

Weight-only quantization is important for compressing Large Language Models (LLMs). Inspired by the spirit of classical magnitude pruning, we study whether the magnitude of weight updates during reasoning-incentivized fine-tuning can provide valuable signals for quantizing Large Reasoning Models (LRMs). We hypothesize that the smallest and largest weight updates during fine-tuning are more important than those of intermediate magnitude, a phenomenon we term "protecting both ends". Upon hypothesis validation, we introduce QuantLRM, which stands for weight quantization of LRMs via fine-tuning signals. We fit simple restricted quadratic functions on weight updates to protect both ends. By multiplying the average quadratic values with the count of zero weight updates of channels, we compute channel importance that is more effective than using activation or second-order information. We run QuantLRM to quantize various fine-tuned models (including supervised, direct preference optimization, and reinforcement learning fine-tuning) over four reasoning benchmarks (AIME-120, FOLIO, temporal sequences, and GPQA-Diamond) and empirically find that QuantLRM delivers a consistent improvement for LRMs quantization, with an average improvement of 6.55% on a reinforcement learning fine-tuned model. Also supporting non-fine-tuned LRMs, QuantLRM gathers effective signals via pseudo-fine-tuning, which greatly enhances its applicability.

Triage: Hierarchical Visual Budgeting for Efficient Video Reasoning in Vision-Language Models

Vision-Language Models (VLMs) face significant computational challenges in video processing due to massive data redundancy, which creates prohibitively long token sequences. To address this, we introduce Triage, a training-free, plug-and-play framework that reframes video reasoning as a resource allocation problem via hierarchical visual budgeting. Its first stage, Frame-Level Budgeting, identifies keyframes by evaluating their visual dynamics and relevance, generating a strategic prior based on their importance scores. Guided by this prior, the second stage, Token-Level Budgeting, allocates tokens in two phases: it first secures high-relevance Core Tokens, followed by diverse Context Tokens selected with an efficient batched Maximal Marginal Relevance (MMR) algorithm. Extensive experiments demonstrate that Triage improves inference speed and reduces memory footprint, while maintaining or surpassing the performance of baselines and other methods on various video reasoning benchmarks.

On the Nonasymptotic Scaling Guarantee of Hyperparameter Estimation in Inhomogeneous, Weakly-Dependent Complex Network Dynamical Systems

Hierarchical Bayesian models are increasingly used in large, inhomogeneous complex network dynamical systems by modeling parameters as draws from a hyperparameter-governed distribution. However, theoretical guarantees for these estimates as the system size grows have been lacking. A critical concern is that hyperparameter estimation may diverge for larger networks, undermining the model's reliability. Formulating the system's evolution in a measure transport perspective, we propose a theoretical framework for estimating hyperparameters with mean-type observations, which are prevalent in many scientific applications. Our primary contribution is a nonasymptotic bound for the deviation of estimate of hyperparameters in inhomogeneous complex network dynamical systems with respect to network population size, which is established for a general family of optimization algorithms within a fixed observation duration. While we firstly establish a consistency result for systems with independent nodes, our main result extends this guarantee to the more challenging and realistic setting of weakly-dependent nodes. We validate our theoretical findings with numerical experiments on two representative models: a Susceptible-Infected-Susceptible model and a Spiking Neuronal Network model. In both cases, the results confirm that the estimation error decreases as the network population size increases, aligning with our theoretical guarantees. This research proposes the foundational theory to ensure that hierarchical Bayesian methods are statistically consistent for large-scale inhomogeneous systems, filling a gap in this area of theoretical research and justifying their application in practice.

Kinematically Controllable Cable Robots with Reconfigurable End-effectors

To enlarge the translational workspace of cable-driven robots, one common approach is to increase the number of cables. However, this introduces two challenges: (1) cable interference significantly reduces the rotational workspace, and (2) the solution of tensions in cables becomes non-unique, resulting in difficulties for kinematic control of the robot. In this work, we design structurally simple reconfigurable end-effectors for cable robots. By incorporating a spring, a helical-grooved shaft, and a matching nut, relative linear motions between end-effector components are converted into relative rotations, thereby expanding the rotational workspace of the mechanism. Meanwhile, a bearing is introduced to provide an additional rotational degree of freedom, making the mechanism non-redundant. As a result, the robot's motion can be controlled purely through kinematics without additional tension sensing and control.

Understanding the Thinking Process of Reasoning Models: A Perspective from Schoenfeld's Episode Theory

While Large Reasoning Models (LRMs) generate extensive chain-of-thought reasoning, we lack a principled framework for understanding how these thoughts are structured. In this paper, we introduce a novel approach by applying Schoenfeld's Episode Theory, a classic cognitive framework for human mathematical problem-solving, to analyze the reasoning traces of LRMs. We annotated thousands of sentences and paragraphs from model-generated solutions to math problems using seven cognitive labels (e.g., Plan, Implement, Verify). The result is the first publicly available benchmark for the fine-grained analysis of machine reasoning, including a large annotated corpus and detailed annotation guidebooks. Our preliminary analysis reveals distinct patterns in LRM reasoning, such as the transition dynamics between cognitive states. This framework provides a theoretically grounded methodology for interpreting LRM cognition and enables future work on more controllable and transparent reasoning systems.

TaxoAdapt: Aligning LLM-Based Multidimensional Taxonomy Construction to Evolving Research Corpora

The rapid evolution of scientific fields introduces challenges in organizing and retrieving scientific literature. While expert-curated taxonomies have traditionally addressed this need, the process is time-consuming and expensive. Furthermore, recent automatic taxonomy construction methods either (1) over-rely on a specific corpus, sacrificing generalizability, or (2) depend heavily on the general knowledge of large language models (LLMs) contained within their pre-training datasets, often overlooking the dynamic nature of evolving scientific domains. Additionally, these approaches fail to account for the multi-faceted nature of scientific literature, where a single research paper may contribute to multiple dimensions (e.g., methodology, new tasks, evaluation metrics, benchmarks). To address these gaps, we propose TaxoAdapt, a framework that dynamically adapts an LLM-generated taxonomy to a given corpus across multiple dimensions. TaxoAdapt performs iterative hierarchical classification, expanding both the taxonomy width and depth based on corpus' topical distribution. We demonstrate its state-of-the-art performance across a diverse set of computer science conferences over the years to showcase its ability to structure and capture the evolution of scientific fields. As a multidimensional method, TaxoAdapt generates taxonomies that are 26.51% more granularity-preserving and 50.41% more coherent than the most competitive baselines judged by LLMs.

Multimodal Machine Translation with Visual Scene Graph Pruning

Multimodal machine translation (MMT) seeks to address the challenges posed by linguistic polysemy and ambiguity in translation tasks by incorporating visual information. A key bottleneck in current MMT research is the effective utilization of visual data. Previous approaches have focused on extracting global or region-level image features and using attention or gating mechanisms for multimodal information fusion. However, these methods have not adequately tackled the issue of visual information redundancy in MMT, nor have they proposed effective solutions. In this paper, we introduce a novel approach--multimodal machine translation with visual Scene Graph Pruning (PSG), which leverages language scene graph information to guide the pruning of redundant nodes in visual scene graphs, thereby reducing noise in downstream translation tasks. Through extensive comparative experiments with state-of-the-art methods and ablation studies, we demonstrate the effectiveness of the PSG model. Our results also highlight the promising potential of visual information pruning in advancing the field of MMT.