PhyAVBench: A Challenging Audio Physics-Sensitivity Benchmark for Physically Grounded Text-to-Audio-Video Generation

Text-to-audio-video (T2AV) generation underpins a wide range of applications demanding realistic audio-visual content, including virtual reality, world modeling, gaming, and filmmaking. However, existing T2AV models remain incapable of generating physically plausible sounds, primarily due to their limited understanding of physical principles. To situate current research progress, we present PhyAVBench, a challenging audio physics-sensitivity benchmark designed to systematically evaluate the audio physics grounding capabilities of existing T2AV models. PhyAVBench comprises 1,000 groups of paired text prompts with controlled physical variables that implicitly induce sound variations, enabling a fine-grained assessment of models' sensitivity to changes in underlying acoustic conditions. We term this evaluation paradigm the Audio-Physics Sensitivity Test (APST). Unlike prior benchmarks that primarily focus on audio-video synchronization, PhyAVBench explicitly evaluates models' understanding of the physical mechanisms underlying sound generation, covering 6 major audio physics dimensions, 4 daily scenarios (music, sound effects, speech, and their mix), and 50 fine-grained test points, ranging from fundamental aspects such as sound diffraction to more complex phenomena, e.g., Helmholtz resonance. Each test point consists of multiple groups of paired prompts, where each prompt is grounded by at least 20 newly recorded or collected real-world videos, thereby minimizing the risk of data leakage during model pre-training. Both prompts and videos are iteratively refined through rigorous human-involved error correction and quality control to ensure high quality. We argue that only models with a genuine grasp of audio-related physical principles can generate physically consistent audio-visual content. We hope PhyAVBench will stimulate future progress in this critical yet largely unexplored domain.

How Far are Modern Trackers from UAV-Anti-UAV? A Million-Scale Benchmark and New Baseline

Unmanned Aerial Vehicles (UAVs) offer wide-ranging applications but also pose significant safety and privacy violation risks in areas like airport and infrastructure inspection, spurring the rapid development of Anti-UAV technologies in recent years. However, current Anti-UAV research primarily focuses on RGB, infrared (IR), or RGB-IR videos captured by fixed ground cameras, with little attention to tracking target UAVs from another moving UAV platform. To fill this gap, we propose a new multi-modal visual tracking task termed UAV-Anti-UAV, which involves a pursuer UAV tracking a target adversarial UAV in the video stream. Compared to existing Anti-UAV tasks, UAV-Anti-UAV is more challenging due to severe dual-dynamic disturbances caused by the rapid motion of both the capturing platform and the target. To advance research in this domain, we construct a million-scale dataset consisting of 1,810 videos, each manually annotated with bounding boxes, a language prompt, and 15 tracking attributes. Furthermore, we propose MambaSTS, a Mamba-based baseline method for UAV-Anti-UAV tracking, which enables integrated spatial-temporal-semantic learning. Specifically, we employ Mamba and Transformer models to learn global semantic and spatial features, respectively, and leverage the state space model's strength in long-sequence modeling to establish video-level long-term context via a temporal token propagation mechanism. We conduct experiments on the UAV-Anti-UAV dataset to validate the effectiveness of our method. A thorough experimental evaluation of 50 modern deep tracking algorithms demonstrates that there is still significant room for improvement in the UAV-Anti-UAV domain. The dataset and codes will be available at {\color{magenta}https://github.com/983632847/Awesome-Multimodal-Object-Tracking}.

A Specialized Large Language Model for Clinical Reasoning and Diagnosis in Rare Diseases

Rare diseases affect hundreds of millions worldwide, yet diagnosis often spans years. Convectional pipelines decouple noisy evidence extraction from downstream inferential diagnosis, and general/medical large language models (LLMs) face scarce real world electronic health records (EHRs), stale domain knowledge, and hallucinations. We assemble a large, domain specialized clinical corpus and a clinician validated reasoning set, and develop RareSeek R1 via staged instruction tuning, chain of thought learning, and graph grounded retrieval. Across multicenter EHR narratives and public benchmarks, RareSeek R1 attains state of the art accuracy, robust generalization, and stability under noisy or overlapping phenotypes. Augmented retrieval yields the largest gains when narratives pair with prioritized variants by resolving ambiguity and aligning candidates to mechanisms. Human studies show performance on par with experienced physicians and consistent gains in assistive use. Notably, transparent reasoning highlights decisive non phenotypic evidence (median 23.1%, such as imaging, interventions, functional tests) underpinning many correct diagnoses. This work advances a narrative first, knowledge integrated reasoning paradigm that shortens the diagnostic odyssey and enables auditable, clinically translatable decision support.

Hi-Reco: High-Fidelity Real-Time Conversational Digital Humans

High-fidelity digital humans are increasingly used in interactive applications, yet achieving both visual realism and real-time responsiveness remains a major challenge. We present a high-fidelity, real-time conversational digital human system that seamlessly combines a visually realistic 3D avatar, persona-driven expressive speech synthesis, and knowledge-grounded dialogue generation. To support natural and timely interaction, we introduce an asynchronous execution pipeline that coordinates multi-modal components with minimal latency. The system supports advanced features such as wake word detection, emotionally expressive prosody, and highly accurate, context-aware response generation. It leverages novel retrieval-augmented methods, including history augmentation to maintain conversational flow and intent-based routing for efficient knowledge access. Together, these components form an integrated system that enables responsive and believable digital humans, suitable for immersive applications in communication, education, and entertainment.

Fifty Years of SAR Automatic Target Recognition: The Road Forward

This paper provides the first comprehensive review of fifty years of synthetic aperture radar automatic target recognition (SAR ATR) development, tracing its evolution from inception to the present day. Central to our analysis is the inheritance and refinement of traditional methods, such as statistical modeling, scattering center analysis, and feature engineering, within modern deep learning frameworks. The survey clearly distinguishes long-standing challenges that have been substantially mitigated by deep learning from newly emerging obstacles. We synthesize recent advances in physics-guided deep learning and propose future directions toward more generalizable and physically-consistent SAR ATR. Additionally, we provide a systematically organized compilation of all publicly available SAR datasets, complete with direct links to support reproducibility and benchmarking. This work not only documents the technical evolution of the field but also offers practical resources and forward-looking insights for researchers and practitioners. A systematic summary of existing literature, code, and datasets are open-sourced at \href{https://github.com/JoyeZLearning/SAR-ATR-From-Beginning-to-Present}{https://github.com/JoyeZLearning/SAR-ATR-From-Beginning-to-Present}.

LAVA: Language Model Assisted Verbal Autopsy for Cause-of-Death Determination

Verbal autopsy (VA) is a critical tool for estimating causes of death in resource-limited settings where medical certification is unavailable. This study presents LA-VA, a proof-of-concept pipeline that combines Large Language Models (LLMs) with traditional algorithmic approaches and embedding-based classification for improved cause-of-death prediction. Using the Population Health Metrics Research Consortium (PHMRC) dataset across three age categories (Adult: 7,580; Child: 1,960; Neonate: 2,438), we evaluate multiple approaches: GPT-5 predictions, LCVA baseline, text embeddings, and meta-learner ensembles. Our results demonstrate that GPT-5 achieves the highest individual performance with average test site accuracies of 48.6% (Adult), 50.5% (Child), and 53.5% (Neonate), outperforming traditional statistical machine learning baselines by 5-10%. Our findings suggest that simple off-the-shelf LLM-assisted approaches could substantially improve verbal autopsy accuracy, with important implications for global health surveillance in low-resource settings.

Quantum-Enhanced Multi-Task Learning with Learnable Weighting for Pharmacokinetic and Toxicity Prediction

Prediction for ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) plays a crucial role in drug discovery and development, accelerating the screening and optimization of new drugs. Existing methods primarily rely on single-task learning (STL), which often fails to fully exploit the complementarities between tasks. Besides, it requires more computational resources while training and inference of each task independently. To address these issues, we propose a new unified Quantum-enhanced and task-Weighted Multi-Task Learning (QW-MTL) framework, specifically designed for ADMET classification tasks. Built upon the Chemprop-RDKit backbone, QW-MTL adopts quantum chemical descriptors to enrich molecular representations with additional information about the electronic structure and interactions. Meanwhile, it introduces a novel exponential task weighting scheme that combines dataset-scale priors with learnable parameters to achieve dynamic loss balancing across tasks. To the best of our knowledge, this is the first work to systematically conduct joint multi-task training across all 13 Therapeutics Data Commons (TDC) classification benchmarks, using leaderboard-style data splits to ensure a standardized and realistic evaluation setting. Extensive experimental results show that QW-MTL significantly outperforms single-task baselines on 12 out of 13 tasks, achieving high predictive performance with minimal model complexity and fast inference, demonstrating the effectiveness and efficiency of multi-task molecular learning enhanced by quantum-informed features and adaptive task weighting.

HSA-Net: Hierarchical and Structure-Aware Framework for Efficient and Scalable Molecular Language Modeling

Molecular representation learning, a cornerstone for downstream tasks like molecular captioning and molecular property prediction, heavily relies on Graph Neural Networks (GNN). However, GNN suffers from the over-smoothing problem, where node-level features collapse in deep GNN layers. While existing feature projection methods with cross-attention have been introduced to mitigate this issue, they still perform poorly in deep features. This motivated our exploration of using Mamba as an alternative projector for its ability to handle complex sequences. However, we observe that while Mamba excels at preserving global topological information from deep layers, it neglects fine-grained details in shallow layers. The capabilities of Mamba and cross-attention exhibit a global-local trade-off. To resolve this critical global-local trade-off, we propose Hierarchical and Structure-Aware Network (HSA-Net), a novel framework with two modules that enables a hierarchical feature projection and fusion. Firstly, a Hierarchical Adaptive Projector (HAP) module is introduced to process features from different graph layers. It learns to dynamically switch between a cross-attention projector for shallow layers and a structure-aware Graph-Mamba projector for deep layers, producing high-quality, multi-level features. Secondly, to adaptively merge these multi-level features, we design a Source-Aware Fusion (SAF) module, which flexibly selects fusion experts based on the characteristics of the aggregation features, ensuring a precise and effective final representation fusion. Extensive experiments demonstrate that our HSA-Net framework quantitatively and qualitatively outperforms current state-of-the-art (SOTA) methods.

Rapid Salient Object Detection with Difference Convolutional Neural Networks

This paper addresses the challenge of deploying salient object detection (SOD) on resource-constrained devices with real-time performance. While recent advances in deep neural networks have improved SOD, existing top-leading models are computationally expensive. We propose an efficient network design that combines traditional wisdom on SOD and the representation power of modern CNNs. Like biologically-inspired classical SOD methods relying on computing contrast cues to determine saliency of image regions, our model leverages Pixel Difference Convolutions (PDCs) to encode the feature contrasts. Differently, PDCs are incorporated in a CNN architecture so that the valuable contrast cues are extracted from rich feature maps. For efficiency, we introduce a difference convolution reparameterization (DCR) strategy that embeds PDCs into standard convolutions, eliminating computation and parameters at inference. Additionally, we introduce SpatioTemporal Difference Convolution (STDC) for video SOD, enhancing the standard 3D convolution with spatiotemporal contrast capture. Our models, SDNet for image SOD and STDNet for video SOD, achieve significant improvements in efficiency-accuracy trade-offs. On a Jetson Orin device, our models with $<$ 1M parameters operate at 46 FPS and 150 FPS on streamed images and videos, surpassing the second-best lightweight models in our experiments by more than $2\times$ and $3\times$ in speed with superior accuracy. Code will be available at https://github.com/hellozhuo/stdnet.git.

Probing Deep into Temporal Profile Makes the Infrared Small Target Detector Much Better

Infrared small target (IRST) detection is challenging in simultaneously achieving precise, universal, robust and efficient performance due to extremely dim targets and strong interference. Current learning-based methods attempt to leverage ``more" information from both the spatial and the short-term temporal domains, but suffer from unreliable performance under complex conditions while incurring computational redundancy. In this paper, we explore the ``more essential" information from a more crucial domain for the detection. Through theoretical analysis, we reveal that the global temporal saliency and correlation information in the temporal profile demonstrate significant superiority in distinguishing target signals from other signals. To investigate whether such superiority is preferentially leveraged by well-trained networks, we built the first prediction attribution tool in this field and verified the importance of the temporal profile information. Inspired by the above conclusions, we remodel the IRST detection task as a one-dimensional signal anomaly detection task, and propose an efficient deep temporal probe network (DeepPro) that only performs calculations in the time dimension for IRST detection. We conducted extensive experiments to fully validate the effectiveness of our method. The experimental results are exciting, as our DeepPro outperforms existing state-of-the-art IRST detection methods on widely-used benchmarks with extremely high efficiency, and achieves a significant improvement on dim targets and in complex scenarios. We provide a new modeling domain, a new insight, a new method, and a new performance, which can promote the development of IRST detection. Codes are available at https://github.com/TinaLRJ/DeepPro.