Morphology-Aware Implicit Super-Resolution Network for Pathological Images

Accurate diagnosis in Digital Pathology (DP) relies on high-resolution whole-slide images, yet clinical deployment is often limited by hardware costs. Super-Resolution (SR) offers a promising alternative by computationally enhancing low-resolution acquisitions. However, existing SR methods frequently struggle to preserve fine-grained cellular morphology, leading to texture oversmoothing and blurred structural boundaries under complex tissue variability. To address this issue, we propose Morph-ISR, a morphology-aware implicit super-resolution framework for DP that restores diagnostically relevant details with sub-pixel precision. Morph-ISR reformulates SR as a continuous coordinate-based reconstruction problem and integrates an Implicit Position-aware Kernel Generator (IPKG) to adaptively model spatially varying tissue morphology. To further enhance structural fidelity, a Morphological Fidelity Prior (MFP) is introduced, leveraging semantic guidance from a pre-trained cell segmentation network to enforce boundary-preserving and region-aware reconstruction, thereby improving the representation of critical cellular boundaries and nuclear textures. Experiments on TCGA and SurGen datasets show that Morph-ISR achieves the best LPIPS and ST-LPIPS among the evaluated methods, reducing them by up to 38.37% and 39.55%, respectively, over the second-best methods while maintaining strong PSNR and SSIM. These results demonstrate superior preservation of diagnostically relevant cellular boundaries and nuclear textures, while compact parameterization and high throughput support efficient edge deployment. Code and trained models will be released upon publication.

S$^3$-Diff: Structural Semantic Synergy Diffusion Model for High Fidelity Super Resolution of Pathological Images

Digital pathology relies on high-resolution whole slide images for accurate diagnosis, yet limitations in imaging devices, storage, and transmission often make lower-resolution pathology images more common in clinical workflows. Current super-resolution techniques often tend to smooth diagnostically relevant morphology, leading to over-smoothed textures and semantic drift that compromise downstream clinical interpretation. To this end, we develop the Structural Semantic Synergy Diffusion Model (S3-Diff), a diffusion framework for high-fidelity super-resolution of pathological images. The core of S3-Diff is Specimen-aware Structural Anchoring (SSA), which combines prognosis-aware tissue support extracted by a fixed SAM with LR-HR gradient discrepancies to generate a specimen-specific structural anchor to preserve pathological morphology. Concurrently, we introduce Structure-guided Semantic Fidelity Tuning (SSFT) to adapt DINOv3 representations using SSA-derived structural supervision. SSFT combines the adapted semantic energy with LR-derived edge and grayscale cues. The resulting control guides denoising to suppress stochastic artifacts and maintain structural consistency. Extensive experimental results demonstrate that S3-Diff consistently outperforms state-of-the-art methods in both reconstruction quality and downstream survival analysis performance. The source code will be made public.

DeltaFlow: Noise-Adaptive Bidirectional Gated Delta Networks for Embedded Language Flows

Embedded Language Flows (ELF) rely primarily on full non-causal attention for iterative denoising, repeatedly incurring quadratic sequence-mixing cost at each sampling step. Gated Delta Networks (GDNs) provide an efficient recurrent alternative, but their standard causal formulation cannot directly capture the bidirectional context required by ELF. We introduce DeltaFlow, a noise-adaptive bidirectional GDN backbone for continuous language denoising. We study two variants: DeltaFlow-A, which alternates scan directions across layers, and DeltaFlow-P, which performs parallel forward and backward scans within each layer. We further introduce noise-adaptive memory control and scheduled Temporal State Consistency (TSC) to stabilize hidden representations across nearby noise levels. On OpenWebText, using a 32-step stochastic differential equation sampler, DeltaFlow-P reduces generated perplexity from 24.218 for the full-attention ELF baseline to 21.228 while maintaining comparable unigram entropy, with 36B training-token exposure compared with 45B for the baseline. In a denoiser-only benchmark, DeltaFlow-P achieves a 2.72x throughput speedup over the full-attention baseline at a sequence length of 16k. These results show that DeltaFlow is a promising alternative to dense attention for efficient continuous language denoising.

AeroAct: Action-Centered World-Action Models for Language-Conditioned Quadrotor Flight

Language-conditioned quadrotor flight requires a policy to ground semantic goals, anticipate the visual consequences of ego-motion, and output control references that remain smooth and dynamically executable under rapidly changing first-person views. Existing aerial vision-language navigation and vision-language-action methods commonly use discrete actions, high-level waypoints, or instantaneous velocity commands, which provide limited supervision about how flight actions change future observations. We present AeroAct, an action-centered world-action model (WAM) for quadrotor navigation. To the best of our knowledge, AeroAct is the first WAM instantiated and demonstrated for real-world aerial flight. The model adapts a pretrained video diffusion Transformer to predict local trajectory-action chunks from egocentric visual history, proprioception, and language. Future first-person frames are used during training as dense consequence supervision, while deployment directly decodes actions without generating future video. To obtain aligned visual, state, language, and dynamically feasible action data, we build a DiffAero-based pipeline with complementary Isaac Lab and 3D Gaussian splatting renderers. We further introduce a low-cost handheld collection device that couples camera observations with motion estimates to recreate flight-like egocentric trajectories, and a self-guidance procedure that improves temporal consistency across overlapping trajectory chunks. Closed-loop simulation and real-world experiments show that temporal visual context improves target tracking and object-search performance, and that WAM-based policies can be executed on a physical quadrotor.

Cura 1T: Specialized Model for Agentic Healthcare

Healthcare spans high-stakes communication, expert reasoning, and workflow execution, yet specialized LLMs that cover these use cases together remain limited. A healthcare model must handle patient consultation, clinical reasoning over text and images, interactive diagnosis, and electronic health record (EHR) tool use. These capabilities fail in different ways, and a narrow update for one task can degrade another. We present Cura 1T, a healthcare-specialized LLM trained through a human-gated self-evolution loop. In each evolution round, a training agent plans a target capability, trains the model, evaluates benchmark trajectories, and refines the data mixture from observed failures. This data-centered loop improves the model through targeted synthetic and curated examples rather than a single generic medical-data update. Across the healthcare evaluation suite, Cura 1T ranks at or near the top among frontier baselines, while remaining competitive on out-of-domain reasoning and agentic benchmarks.

CHM-Net: Center Heatmap-driven Macro-Micro Modeling Network for MRI-based Microbial Density Stratification

Microbial density is clinically important for tumor assessment and treatment decision-making, and recent advances in deep learning suggest that it can be non-invasively inferred from multimodal MRI. In this work, MRI-based Microbial Density Stratification (MRI-MDS) is first investigated as a patient-level representation learning task, and Center Heatmap-driven Macro-micro modeling Network (CHM-Net) is introduced for this task. CHM-Net first establishes the link between imaging phenotypes and microbial states through center heatmap-guided small-lesion response localization. Building upon this, it constructs patient-level macro-micro evidence from localized heatmap responses for microbial density prediction. Experiments on the novel GBNPC 2026 dataset constructed for MRI-MDS demonstrate the effectiveness of CHM-Net, achieving superior performance over representative baselines with a 12.06% absolute ACC gain over the strongest competing result. Additionally, auxiliary validation on two 3D medical image datasets further verifies its robustness across volumetric medical image classification scenarios. The project is available at https://anonymous.4open.science/r/CHM-Net-942E/.

Causal-Transformer with Adaptive Mutation-Locking for Early Prediction of Acute Kidney Injury

Accurate early prediction of Acute Kidney Injury (AKI) is critical for timely clinical intervention. However, existing deep learning models struggle with irregularly sampled data and suffer from the opaque "black-box" nature of sequential architectures, strictly limiting clinical trust. To address these challenges, we propose CT-Former, integrating continuous-time modeling with a Causal-Transformer. To handle data irregularity without biased artificial imputation, our framework utilizes a continuous-time state evolution mechanism to naturally track patient temporal trajectories. To resolve the black-box problem, our Causal-Attention module abandons uninterpretable hidden state aggregation. Instead, it generates a directed structural causal matrix to identify and trace the exact historical onset of severe physiological shocks. By establishing clear causal pathways between historical anomalies and current risk predictions, CT-Former provides native clinical interpretability. Training follows a decoupled two-stage protocol to optimize the causal-fusion process independently. Extensive experiments on the MIMIC-IV cohort (N=18,419) demonstrate that CT-Former significantly outperforms state-of-the-art baselines. The results confirm that our explicitly transparent architecture offers an accurate and trustworthy tool for clinical decision-making.

From Guessing to Placeholding: A Cost-Theoretic Framework for Uncertainty-Aware Code Completion

While Large Language Models (LLMs) have demonstrated exceptional proficiency in code completion, they typically adhere to a Hard Completion (HC) paradigm, compelling the generation of fully concrete code even amidst insufficient context. Our analysis of 3 million real-world interactions exposes the limitations of this strategy: 61% of the generated suggestions were either edited after acceptance or rejected despite exhibiting over 80% similarity to the user's subsequent code, suggesting that models frequently make erroneous predictions at specific token positions. Motivated by this observation, we propose Adaptive Placeholder Completion (APC), a collaborative framework that extends HC by strategically outputting explicit placeholders at high-entropy positions, allowing users to fill directly via IDE navigation. Theoretically, we formulate code completion as a cost-minimization problem under uncertainty. Premised on the observation that filling placeholders incurs lower cost than correcting errors, we prove the existence of a critical entropy threshold above which APC achieves strictly lower expected cost than HC. We instantiate this framework by constructing training data from filtered real-world edit logs and design a cost-based reward function for reinforcement learning. Extensive evaluations across 1.5B--14B parameter models demonstrate that APC reduces expected editing costs from 19% to 50% while preserving standard HC performance. Our work provides both a theoretical foundation and a practical training framework for uncertainty-aware code completion, demonstrating that adaptive abstention can be learned end-to-end without sacrificing conventional completion quality.

Position: Vector Prompt Interfaces Should Be Exposed to Enable Customization of Large Language Models

As large language models (LLMs) transition from research prototypes to real-world systems, customization has emerged as a central bottleneck. While text prompts can already customize LLM behavior, we argue that text-only prompting does not constitute a suitable control interface for scalable, stable, and inference-only customization. This position paper argues that model providers should expose \emph{vector prompt inputs} as part of the public interface for customizing LLMs. We support this position with diagnostic evidence showing that vector prompt tuning continues to improve with increasing supervision whereas text-based prompt optimization saturates early, and that vector prompts exhibit dense, global attention patterns indicative of a distinct control mechanism. We further discuss why inference-only customization is increasingly important under realistic deployment constraints, and why exposing vector prompts need not fundamentally increase model leakage risk under a standard black-box threat model. We conclude with a call to action for the community to rethink prompt interfaces as a core component of LLM customization.

AudioCapBench: Quick Evaluation on Audio Captioning across Sound, Music, and Speech

We introduce AudioCapBench, a benchmark for evaluating audio captioning capabilities of large multimodal models. \method covers three distinct audio domains, including environmental sound, music, and speech, with 1,000 curated evaluation samples drawn from established datasets. We evaluate 13 models across two providers (OpenAI, Google Gemini) using both reference-based metrics (METEOR, BLEU, ROUGE-L) and an LLM-as-Judge framework that scores predictions on three orthogonal dimensions: \textit{accuracy} (semantic correctness), \textit{completeness} (coverage of reference content), and \textit{hallucination} (absence of fabricated content). Our results reveal that Gemini models generally outperform OpenAI models on overall captioning quality, with Gemini~3~Pro achieving the highest overall score (6.00/10), while OpenAI models exhibit lower hallucination rates. All models perform best on speech captioning and worst on music captioning. We release the benchmark as well as evaluation code to facilitate reproducible audio understanding research.