A Good Image Generator Is What You Need for High-Resolution Video Synthesis

Image and video synthesis are closely related areas aiming at generating content from noise. While rapid progress has been demonstrated in improving image-based models to handle large resolutions, high-quality renderings, and wide variations in image content, achieving comparable video generation results remains problematic. We present a framework that leverages contemporary image generators to render high-resolution videos. We frame the video synthesis problem as discovering a trajectory in the latent space of a pre-trained and fixed image generator. Not only does such a framework render high-resolution videos, but it also is an order of magnitude more computationally efficient. We introduce a motion generator that discovers the desired trajectory, in which content and motion are disentangled. With such a representation, our framework allows for a broad range of applications, including content and motion manipulation. Furthermore, we introduce a new task, which we call cross-domain video synthesis, in which the image and motion generators are trained on disjoint datasets belonging to different domains. This allows for generating moving objects for which the desired video data is not available. Extensive experiments on various datasets demonstrate the advantages of our methods over existing video generation techniques. Code will be released at https://github.com/snap-research/MoCoGAN-HD.

SCPM-Net: An Anchor-free 3D Lung Nodule Detection Network using Sphere Representation and Center Points Matching

Automatic and accurate lung nodule detection from 3D Computed Tomography scans plays a vital role in efficient lung cancer screening. Despite the state-of-the-art performance obtained by recent anchor-based detectors using Convolutional Neural Networks, they require predetermined anchor parameters such as the size, number, and aspect ratio of anchors, and have limited robustness when dealing with lung nodules with a massive variety of sizes. We propose a 3D sphere representation-based center-points matching detection network (SCPM-Net) that is anchor-free and automatically predicts the position, radius, and offset of nodules without the manual design of nodule/anchor parameters. The SCPM-Net consists of two novel pillars: sphere representation and center points matching. To mimic the nodule annotation in clinical practice, we replace the conventional bounding box with the newly proposed bounding sphere. A compatible sphere-based intersection over-union loss function is introduced to train the lung nodule detection network stably and efficiently.We empower the network anchor-free by designing a positive center-points selection and matching (CPM) process, which naturally discards pre-determined anchor boxes. An online hard example mining and re-focal loss subsequently enable the CPM process more robust, resulting in more accurate point assignment and the mitigation of class imbalance. In addition, to better capture spatial information and 3D context for the detection, we propose to fuse multi-level spatial coordinate maps with the feature extractor and combine them with 3D squeeze-and-excitation attention modules. Experimental results on the LUNA16 dataset showed that our proposed SCPM-Net framework achieves superior performance compared with existing used anchor-based and anchor-free methods for lung nodule detection.

Deep Animation Video Interpolation in the Wild

In the animation industry, cartoon videos are usually produced at low frame rate since hand drawing of such frames is costly and time-consuming. Therefore, it is desirable to develop computational models that can automatically interpolate the in-between animation frames. However, existing video interpolation methods fail to produce satisfying results on animation data. Compared to natural videos, animation videos possess two unique characteristics that make frame interpolation difficult: 1) cartoons comprise lines and smooth color pieces. The smooth areas lack textures and make it difficult to estimate accurate motions on animation videos. 2) cartoons express stories via exaggeration. Some of the motions are non-linear and extremely large. In this work, we formally define and study the animation video interpolation problem for the first time. To address the aforementioned challenges, we propose an effective framework, AnimeInterp, with two dedicated modules in a coarse-to-fine manner. Specifically, 1) Segment-Guided Matching resolves the "lack of textures" challenge by exploiting global matching among color pieces that are piece-wise coherent. 2) Recurrent Flow Refinement resolves the "non-linear and extremely large motion" challenge by recurrent predictions using a transformer-like architecture. To facilitate comprehensive training and evaluations, we build a large-scale animation triplet dataset, ATD-12K, which comprises 12,000 triplets with rich annotations. Extensive experiments demonstrate that our approach outperforms existing state-of-the-art interpolation methods for animation videos. Notably, AnimeInterp shows favorable perceptual quality and robustness for animation scenarios in the wild. The proposed dataset and code are available at https://github.com/lisiyao21/AnimeInterp/.

FocusNetv2: Imbalanced Large and Small Organ Segmentation with Adversarial Shape Constraint for Head and Neck CT Images

Radiotherapy is a treatment where radiation is used to eliminate cancer cells. The delineation of organs-at-risk (OARs) is a vital step in radiotherapy treatment planning to avoid damage to healthy organs. For nasopharyngeal cancer, more than 20 OARs are needed to be precisely segmented in advance. The challenge of this task lies in complex anatomical structure, low-contrast organ contours, and the extremely imbalanced size between large and small organs. Common segmentation methods that treat them equally would generally lead to inaccurate small-organ labeling. We propose a novel two-stage deep neural network, FocusNetv2, to solve this challenging problem by automatically locating, ROI-pooling, and segmenting small organs with specifically designed small-organ localization and segmentation sub-networks while maintaining the accuracy of large organ segmentation. In addition to our original FocusNet, we employ a novel adversarial shape constraint on small organs to ensure the consistency between estimated small-organ shapes and organ shape prior knowledge. Our proposed framework is extensively tested on both self-collected dataset of 1,164 CT scans and the MICCAI Head and Neck Auto Segmentation Challenge 2015 dataset, which shows superior performance compared with state-of-the-art head and neck OAR segmentation methods.

Variational Bayesian Sequence-to-Sequence Networks for Memory-Efficient Sign Language Translation

Memory-efficient continuous Sign Language Translation is a significant challenge for the development of assisted technologies with real-time applicability for the deaf. In this work, we introduce a paradigm of designing recurrent deep networks whereby the output of the recurrent layer is derived from appropriate arguments from nonparametric statistics. A novel variational Bayesian sequence-to-sequence network architecture is proposed that consists of a) a full Gaussian posterior distribution for data-driven memory compression and b) a nonparametric Indian Buffet Process prior for regularization applied on the Gated Recurrent Unit non-gate weights. We dub our approach Stick-Breaking Recurrent network and show that it can achieve a substantial weight compression without diminishing modeling performance.

Multi-modal AsynDGAN: Learn From Distributed Medical Image Data without Sharing Private Information

As deep learning technologies advance, increasingly more data is necessary to generate general and robust models for various tasks. In the medical domain, however, large-scale and multi-parties data training and analyses are infeasible due to the privacy and data security concerns. In this paper, we propose an extendable and elastic learning framework to preserve privacy and security while enabling collaborative learning with efficient communication. The proposed framework is named distributed Asynchronized Discriminator Generative Adversarial Networks (AsynDGAN), which consists of a centralized generator and multiple distributed discriminators. The advantages of our proposed framework are five-fold: 1) the central generator could learn the real data distribution from multiple datasets implicitly without sharing the image data; 2) the framework is applicable for single-modality or multi-modality data; 3) the learned generator can be used to synthesize samples for down-stream learning tasks to achieve close-to-real performance as using actual samples collected from multiple data centers; 4) the synthetic samples can also be used to augment data or complete missing modalities for one single data center; 5) the learning process is more efficient and requires lower bandwidth than other distributed deep learning methods.

Learning Trailer Moments in Full-Length Movies

A movie's key moments stand out of the screenplay to grab an audience's attention and make movie browsing efficient. But a lack of annotations makes the existing approaches not applicable to movie key moment detection. To get rid of human annotations, we leverage the officially-released trailers as the weak supervision to learn a model that can detect the key moments from full-length movies. We introduce a novel ranking network that utilizes the Co-Attention between movies and trailers as guidance to generate the training pairs, where the moments highly corrected with trailers are expected to be scored higher than the uncorrelated moments. Additionally, we propose a Contrastive Attention module to enhance the feature representations such that the comparative contrast between features of the key and non-key moments are maximized. We construct the first movie-trailer dataset, and the proposed Co-Attention assisted ranking network shows superior performance even over the supervised approach. The effectiveness of our Contrastive Attention module is also demonstrated by the performance improvement over the state-of-the-art on the public benchmarks.

Weakly Supervised Deep Nuclei Segmentation Using Partial Points Annotation in Histopathology Images

Nuclei segmentation is a fundamental task in histopathology image analysis. Typically, such segmentation tasks require significant effort to manually generate accurate pixel-wise annotations for fully supervised training. To alleviate such tedious and manual effort, in this paper we propose a novel weakly supervised segmentation framework based on partial points annotation, i.e., only a small portion of nuclei locations in each image are labeled. The framework consists of two learning stages. In the first stage, we design a semi-supervised strategy to learn a detection model from partially labeled nuclei locations. Specifically, an extended Gaussian mask is designed to train an initial model with partially labeled data. Then, selftraining with background propagation is proposed to make use of the unlabeled regions to boost nuclei detection and suppress false positives. In the second stage, a segmentation model is trained from the detected nuclei locations in a weakly-supervised fashion. Two types of coarse labels with complementary information are derived from the detected points and are then utilized to train a deep neural network. The fully-connected conditional random field loss is utilized in training to further refine the model without introducing extra computational complexity during inference. The proposed method is extensively evaluated on two nuclei segmentation datasets. The experimental results demonstrate that our method can achieve competitive performance compared to the fully supervised counterpart and the state-of-the-art methods while requiring significantly less annotation effort.

Knowledge as Priors: Cross-Modal Knowledge Generalization for Datasets without Superior Knowledge

Cross-modal knowledge distillation deals with transferring knowledge from a model trained with superior modalities (Teacher) to another model trained with weak modalities (Student). Existing approaches require paired training examples exist in both modalities. However, accessing the data from superior modalities may not always be feasible. For example, in the case of 3D hand pose estimation, depth maps, point clouds, or stereo images usually capture better hand structures than RGB images, but most of them are expensive to be collected. In this paper, we propose a novel scheme to train the Student in a Target dataset where the Teacher is unavailable. Our key idea is to generalize the distilled cross-modal knowledge learned from a Source dataset, which contains paired examples from both modalities, to the Target dataset by modeling knowledge as priors on parameters of the Student. We name our method "Cross-Modal Knowledge Generalization" and demonstrate that our scheme results in competitive performance for 3D hand pose estimation on standard benchmark datasets.

Vertebra-Focused Landmark Detection for Scoliosis Assessment

Adolescent idiopathic scoliosis (AIS) is a lifetime disease that arises in children. Accurate estimation of Cobb angles of the scoliosis is essential for clinicians to make diagnosis and treatment decisions. The Cobb angles are measured according to the vertebrae landmarks. Existing regression-based methods for the vertebra landmark detection typically suffer from large dense mapping parameters and inaccurate landmark localization. The segmentation-based methods tend to predict connected or corrupted vertebra masks. In this paper, we propose a novel vertebra-focused landmark detection method. Our model first localizes the vertebra centers, based on which it then traces the four corner landmarks of the vertebra through the learned corner offset. In this way, our method is able to keep the order of the landmarks. The comparison results demonstrate the merits of our method in both Cobb angle measurement and landmark detection on low-contrast and ambiguous X-ray images. Code is available at: \url{https://github.com/yijingru/Vertebra-Landmark-Detection}.