School of Optoelectronic Science and Engineering, Soochow University
Abstract:Forensic cause-of-death determination faces systemic challenges, including workforce shortages and diagnostic variability, particularly in high-volume systems like China's medicolegal infrastructure. We introduce FEAT (ForEnsic AgenT), a multi-agent AI framework that automates and standardizes death investigations through a domain-adapted large language model. FEAT's application-oriented architecture integrates: (i) a central Planner for task decomposition, (ii) specialized Local Solvers for evidence analysis, (iii) a Memory & Reflection module for iterative refinement, and (iv) a Global Solver for conclusion synthesis. The system employs tool-augmented reasoning, hierarchical retrieval-augmented generation, forensic-tuned LLMs, and human-in-the-loop feedback to ensure legal and medical validity. In evaluations across diverse Chinese case cohorts, FEAT outperformed state-of-the-art AI systems in both long-form autopsy analyses and concise cause-of-death conclusions. It demonstrated robust generalization across six geographic regions and achieved high expert concordance in blinded validations. Senior pathologists validated FEAT's outputs as comparable to those of human experts, with improved detection of subtle evidentiary nuances. To our knowledge, FEAT is the first LLM-based AI agent system dedicated to forensic medicine, offering scalable, consistent death certification while maintaining expert-level rigor. By integrating AI efficiency with human oversight, this work could advance equitable access to reliable medicolegal services while addressing critical capacity constraints in forensic systems.
Abstract:Neurophysiological decoding, fundamental to advancing brain-computer interface (BCI) technologies, has significantly benefited from recent advances in deep learning. However, existing decoding approaches largely remain constrained to single-task scenarios and individual subjects, limiting their broader applicability and generalizability. Efforts towards creating large-scale neurophysiological foundation models have shown promise, but continue to struggle with significant challenges due to pervasive data heterogeneity across subjects and decoding tasks. Simply increasing model parameters and dataset size without explicitly addressing this heterogeneity fails to replicate the scaling successes seen in natural language processing. Here, we introduce the Neural Mixture of Brain Regional Experts (Neuro-MoBRE), a general-purpose decoding framework explicitly designed to manage the ubiquitous data heterogeneity in neurophysiological modeling. Neuro-MoBRE incorporates a brain-regional-temporal embedding mechanism combined with a mixture-of-experts approach, assigning neural signals from distinct brain regions to specialized regional experts on a unified embedding basis, thus explicitly resolving both structural and functional heterogeneity. Additionally, our region-masked autoencoding pre-training strategy further enhances representational consistency among subjects, complemented by a task-disentangled information aggregation method tailored to effectively handle task-specific neural variations. Evaluations conducted on intracranial recordings from 11 subjects across five diverse tasks, including complex language decoding and epileptic seizure diagnosis, demonstrate that Neuro-MoBRE surpasses prior art and exhibits robust generalization for zero-shot decoding on unseen subjects.
Abstract:Hyperspectral image denoising faces the challenge of multi-dimensional coupling of spatially non-uniform noise and spectral correlation interference. Existing deep learning methods mostly focus on RGB images and struggle to effectively handle the unique spatial-spectral characteristics and complex noise distributions of hyperspectral images (HSI). This paper proposes an HSI denoising framework, Hybrid-Domain Synergistic Transformer Network (HDST), based on frequency domain enhancement and multiscale modeling, achieving three-dimensional collaborative processing of spatial, frequency and channel domains. The method innovatively integrates three key mechanisms: (1) introducing an FFT preprocessing module with multi-band convolution to extract cross-band correlations and decouple spectral noise components; (2) designing a dynamic cross-domain attention module that adaptively fuses spatial domain texture features and frequency domain noise priors through a learnable gating mechanism; (3) building a hierarchical architecture where shallow layers capture global noise statistics using multiscale atrous convolution, and deep layers achieve detail recovery through frequency domain postprocessing. Experiments on both real and synthetic datasets demonstrate that HDST significantly improves denoising performance while maintaining computational efficiency, validating the effectiveness of the proposed method. This research provides new insights and a universal framework for addressing complex noise coupling issues in HSI and other high-dimensional visual data. The code is available at https://github.com/lhy-cn/HDST-HSIDenoise.
Abstract:Methamphetamine dependence poses a significant global health challenge, yet its assessment and the evaluation of treatments like repetitive transcranial magnetic stimulation (rTMS) frequently depend on subjective self-reports, which may introduce uncertainties. While objective neuroimaging modalities such as electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) offer alternatives, their individual limitations and the reliance on conventional, often hand-crafted, feature extraction can compromise the reliability of derived biomarkers. To overcome these limitations, we propose NeuroCLIP, a novel deep learning framework integrating simultaneously recorded EEG and fNIRS data through a progressive learning strategy. This approach offers a robust and trustworthy biomarker for methamphetamine addiction. Validation experiments show that NeuroCLIP significantly improves discriminative capabilities among the methamphetamine-dependent individuals and healthy controls compared to models using either EEG or only fNIRS alone. Furthermore, the proposed framework facilitates objective, brain-based evaluation of rTMS treatment efficacy, demonstrating measurable shifts in neural patterns towards healthy control profiles after treatment. Critically, we establish the trustworthiness of the multimodal data-driven biomarker by showing its strong correlation with psychometrically validated craving scores. These findings suggest that biomarker derived from EEG-fNIRS data via NeuroCLIP offers enhanced robustness and reliability over single-modality approaches, providing a valuable tool for addiction neuroscience research and potentially improving clinical assessments.
Abstract:Accurate and efficient acquisition of wireless channel state information (CSI) is crucial to enhance the communication performance of wireless systems. However, with the continuous densification of wireless links, increased channel dimensions, and the use of higher-frequency bands, channel estimation in the sixth generation (6G) and beyond wireless networks faces new challenges, such as insufficient orthogonal pilot sequences, inadequate signal-to-noise ratio (SNR) for channel training, and more sophisticated channel statistical distributions in complex environment. These challenges pose significant difficulties for classical channel estimation algorithms like least squares (LS) and maximum a posteriori (MAP). To address this problem, we propose a novel environment-aware channel estimation framework with location-specific prior channel distribution enabled by the new concept of channel knowledge map (CKM). To this end, we propose a new type of CKM called channel score function map (CSFM), which learns the channel probability density function (PDF) using artificial intelligence (AI) techniques. To fully exploit the prior information in CSFM, we propose a plug-and-play (PnP) based algorithm to decouple the regularized MAP channel estimation problem, thereby reducing the complexity of the optimization process. Besides, we employ Tweedie's formula to establish a connection between the channel score function, defined as the logarithmic gradient of the channel PDF, and the channel denoiser. This allows the use of the high-precision, environment-aware channel denoiser from the CSFM to approximate the channel score function, thus enabling efficient processing of the decoupled channel statistical components. Simulation results show that the proposed CSFM-PnP based channel estimation technique significantly outperforms the conventional techniques in the aforementioned challenging scenarios.
Abstract:Soft robots, compared to rigid robots, possess inherent advantages, including higher degrees of freedom, compliance, and enhanced safety, which have contributed to their increasing application across various fields. Among these benefits, adaptability is particularly noteworthy. In this paper, adaptability in soft robots is categorized into external and internal adaptability. External adaptability refers to the robot's ability to adjust, either passively or actively, to variations in environments, object properties, geometries, and task dynamics. Internal adaptability refers to the robot's ability to cope with internal variations, such as manufacturing tolerances or material aging, and to generalize control strategies across different robots. As the field of soft robotics continues to evolve, the significance of adaptability has become increasingly pronounced. In this review, we summarize various approaches to enhancing the adaptability of soft robots, including design, sensing, and control strategies. Additionally, we assess the impact of adaptability on applications such as surgery, wearable devices, locomotion, and manipulation. We also discuss the limitations of soft robotics adaptability and prospective directions for future research. By analyzing adaptability through the lenses of implementation, application, and challenges, this paper aims to provide a comprehensive understanding of this essential characteristic in soft robotics and its implications for diverse applications.
Abstract:Federated Learning (FL) provides a privacy-preserving paradigm for training audio classification (AC) models across distributed clients without sharing raw data. However, Federated Audio Classification (FedAC) faces three critical challenges that substantially hinder performance: data heterogeneity, model heterogeneity, and data poisoning. While prior works have attempted to address these issues, they are typically treated independently, lacking a unified and robust solution suited to real-world federated audio scenarios. To bridge this gap, we propose FedMLAC, a unified mutual learning framework designed to simultaneously tackle these challenges in FedAC. Specifically, FedMLAC introduces a dual-model architecture on each client, comprising a personalized local AC model and a lightweight, globally shared Plug-in model. Through bidirectional knowledge distillation, the Plug-in model enables global knowledge transfer while adapting to client-specific data distributions, thus supporting both generalization and personalization. To further enhance robustness against corrupted audio data, we develop a Layer-wise Pruning Aggregation (LPA) strategy that filters unreliable Plug-in model updates based on parameter deviations during server-side aggregation. Extensive experiments on four diverse audio classification benchmarks, spanning both speech and non-speech tasks, demonstrate that FedMLAC consistently outperforms existing state-of-the-art methods in terms of classification accuracy and robustness to noisy data.
Abstract:As large language models (LLMs) continue to advance, there is a growing urgency to enhance the interpretability of their internal knowledge mechanisms. Consequently, many interpretation methods have emerged, aiming to unravel the knowledge mechanisms of LLMs from various perspectives. However, current interpretation methods differ in input data formats and interpreting outputs. The tools integrating these methods are only capable of supporting tasks with specific inputs, significantly constraining their practical applications. To address these challenges, we present an open-source Knowledge Mechanisms Revealer&Interpreter (Know-MRI) designed to analyze the knowledge mechanisms within LLMs systematically. Specifically, we have developed an extensible core module that can automatically match different input data with interpretation methods and consolidate the interpreting outputs. It enables users to freely choose appropriate interpretation methods based on the inputs, making it easier to comprehensively diagnose the model's internal knowledge mechanisms from multiple perspectives. Our code is available at https://github.com/nlpkeg/Know-MRI. We also provide a demonstration video on https://youtu.be/NVWZABJ43Bs.
Abstract:To manage and optimize constantly evolving wireless networks, existing machine learning (ML)- based studies operate as black-box models, leading to increased computational costs during training and a lack of transparency in decision-making, which limits their practical applicability in wireless networks. Motivated by recent advancements in large language model (LLM)-enabled wireless networks, this paper proposes ProWin, a novel framework that leverages reinforced in-context learning to design task-specific demonstration Prompts for Wireless Network optimization, relying on the inference capabilities of LLMs without the need for dedicated model training or finetuning. The task-specific prompts are designed to incorporate natural language descriptions of the task description and formulation, enhancing interpretability and eliminating the need for specialized expertise in network optimization. We further propose a reinforced in-context learning scheme that incorporates a set of advisable examples into task-specific prompts, wherein informative examples capturing historical environment states and decisions are adaptively selected to guide current decision-making. Evaluations on a case study of base station power control showcases that the proposed ProWin outperforms reinforcement learning (RL)-based methods, highlighting the potential for next-generation future wireless network optimization.
Abstract:Large Language Models (LLMs) demonstrate strong reasoning capabilities for many tasks, often by explicitly decomposing the task via Chain-of-Thought (CoT) reasoning. Recent work on LLM-based translation designs hand-crafted prompts to decompose translation, or trains models to incorporate intermediate steps.~\textit{Translating Step-by-step}~\citep{briakou2024translating}, for instance, introduces a multi-step prompt with decomposition and refinement of translation with LLMs, which achieved state-of-the-art results on WMT24. In this work, we scrutinise this strategy's effectiveness. Empirically, we find no clear evidence that performance gains stem from explicitly decomposing the translation process, at least for the models on test; and we show that simply prompting LLMs to ``translate again'' yields even better results than human-like step-by-step prompting. Our analysis does not rule out the role of reasoning, but instead invites future work exploring the factors for CoT's effectiveness in the context of translation.