Joint Diffusion: Mutual Consistency-Driven Diffusion Model for PET-MRI Co-Reconstruction

Positron Emission Tomography and Magnetic Resonance Imaging (PET-MRI) systems can obtain functional and anatomical scans. PET suffers from a low signal-to-noise ratio. Meanwhile, the k-space data acquisition process in MRI is time-consuming. The study aims to accelerate MRI and enhance PET image quality. Conventional approaches involve the separate reconstruction of each modality within PET-MRI systems. However, there exists complementary information among multi-modal images. The complementary information can contribute to image reconstruction. In this study, we propose a novel PET-MRI joint reconstruction model employing a mutual consistency-driven diffusion mode, namely MC-Diffusion. MC-Diffusion learns the joint probability distribution of PET and MRI for utilizing complementary information. We conducted a series of contrast experiments about LPLS, Joint ISAT-net and MC-Diffusion by the ADNI dataset. The results underscore the qualitative and quantitative improvements achieved by MC-Diffusion, surpassing the state-of-the-art method.

Score-based Diffusion Models With Self-supervised Learning For Accelerated 3D Multi-contrast Cardiac Magnetic Resonance Imaging

Long scan time significantly hinders the widespread applications of three-dimensional multi-contrast cardiac magnetic resonance (3D-MC-CMR) imaging. This study aims to accelerate 3D-MC-CMR acquisition by a novel method based on score-based diffusion models with self-supervised learning. Specifically, we first establish a mapping between the undersampled k-space measurements and the MR images, utilizing a self-supervised Bayesian reconstruction network. Secondly, we develop a joint score-based diffusion model on 3D-MC-CMR images to capture their inherent distribution. The 3D-MC-CMR images are finally reconstructed using the conditioned Langenvin Markov chain Monte Carlo sampling. This approach enables accurate reconstruction without fully sampled training data. Its performance was tested on the dataset acquired by a 3D joint myocardial T1 and T1rho mapping sequence. The T1 and T1rho maps were estimated via a dictionary matching method from the reconstructed images. Experimental results show that the proposed method outperforms traditional compressed sensing and existing self-supervised deep learning MRI reconstruction methods. It also achieves high quality T1 and T1rho parametric maps close to the reference maps obtained by traditional mapping sequences, even at a high acceleration rate of 14.

Physics-Informed DeepMRI: Bridging the Gap from Heat Diffusion to k-Space Interpolation

In the field of parallel imaging (PI), alongside image-domain regularization methods, substantial research has been dedicated to exploring $k$-space interpolation. However, the interpretability of these methods remains an unresolved issue. Furthermore, these approaches currently face acceleration limitations that are comparable to those experienced by image-domain methods. In order to enhance interpretability and overcome the acceleration limitations, this paper introduces an interpretable framework that unifies both $k$-space interpolation techniques and image-domain methods, grounded in the physical principles of heat diffusion equations. Building upon this foundational framework, a novel $k$-space interpolation method is proposed. Specifically, we model the process of high-frequency information attenuation in $k$-space as a heat diffusion equation, while the effort to reconstruct high-frequency information from low-frequency regions can be conceptualized as a reverse heat equation. However, solving the reverse heat equation poses a challenging inverse problem. To tackle this challenge, we modify the heat equation to align with the principles of magnetic resonance PI physics and employ the score-based generative method to precisely execute the modified reverse heat diffusion. Finally, experimental validation conducted on publicly available datasets demonstrates the superiority of the proposed approach over traditional $k$-space interpolation methods, deep learning-based $k$-space interpolation methods, and conventional diffusion models in terms of reconstruction accuracy, particularly in high-frequency regions.

Confidence Ranking for CTR Prediction

Model evolution and constant availability of data are two common phenomena in large-scale real-world machine learning applications, e.g. ads and recommendation systems. To adapt, the real-world system typically retrain with all available data and online learn with recently available data to update the models periodically with the goal of better serving performance. In this paper, we propose a novel framework, named Confidence Ranking, which designs the optimization objective as a ranking function with two different models. Our confidence ranking loss allows direct optimization of the logits output for different convex surrogate functions of metrics, e.g. AUC and Accuracy depending on the target task and dataset. Armed with our proposed methods, our experiments show that the introduction of confidence ranking loss can outperform all baselines on the CTR prediction tasks of public and industrial datasets. This framework has been deployed in the advertisement system of JD.com to serve the main traffic in the fine-rank stage.

Meta-Learning Enabled Score-Based Generative Model for 1.5T-Like Image Reconstruction from 0.5T MRI

Magnetic resonance imaging (MRI) is known to have reduced signal-to-noise ratios (SNR) at lower field strengths, leading to signal degradation when producing a low-field MRI image from a high-field one. Therefore, reconstructing a high-field-like image from a low-field MRI is a complex problem due to the ill-posed nature of the task. Additionally, obtaining paired low-field and high-field MR images is often not practical. We theoretically uncovered that the combination of these challenges renders conventional deep learning methods that directly learn the mapping from a low-field MR image to a high-field MR image unsuitable. To overcome these challenges, we introduce a novel meta-learning approach that employs a teacher-student mechanism. Firstly, an optimal-transport-driven teacher learns the degradation process from high-field to low-field MR images and generates pseudo-paired high-field and low-field MRI images. Then, a score-based student solves the inverse problem of reconstructing a high-field-like MR image from a low-field MRI within the framework of iterative regularization, by learning the joint distribution of pseudo-paired images to act as a regularizer. Experimental results on real low-field MRI data demonstrate that our proposed method outperforms state-of-the-art unpaired learning methods.

Always Strengthen Your Strengths: A Drift-Aware Incremental Learning Framework for CTR Prediction

Click-through rate (CTR) prediction is of great importance in recommendation systems and online advertising platforms. When served in industrial scenarios, the user-generated data observed by the CTR model typically arrives as a stream. Streaming data has the characteristic that the underlying distribution drifts over time and may recur. This can lead to catastrophic forgetting if the model simply adapts to new data distribution all the time. Also, it's inefficient to relearn distribution that has been occurred. Due to memory constraints and diversity of data distributions in large-scale industrial applications, conventional strategies for catastrophic forgetting such as replay, parameter isolation, and knowledge distillation are difficult to be deployed. In this work, we design a novel drift-aware incremental learning framework based on ensemble learning to address catastrophic forgetting in CTR prediction. With explicit error-based drift detection on streaming data, the framework further strengthens well-adapted ensembles and freezes ensembles that do not match the input distribution avoiding catastrophic interference. Both evaluations on offline experiments and A/B test shows that our method outperforms all baselines considered.

K-UNN: k-Space Interpolation With Untrained Neural Network

Recently, untrained neural networks (UNNs) have shown satisfactory performances for MR image reconstruction on random sampling trajectories without using additional full-sampled training data. However, the existing UNN-based approach does not fully use the MR image physical priors, resulting in poor performance in some common scenarios (e.g., partial Fourier, regular sampling, etc.) and the lack of theoretical guarantees for reconstruction accuracy. To bridge this gap, we propose a safeguarded k-space interpolation method for MRI using a specially designed UNN with a tripled architecture driven by three physical priors of the MR images (or k-space data), including sparsity, coil sensitivity smoothness, and phase smoothness. We also prove that the proposed method guarantees tight bounds for interpolated k-space data accuracy. Finally, ablation experiments show that the proposed method can more accurately characterize the physical priors of MR images than existing traditional methods. Additionally, under a series of commonly used sampling trajectories, experiments also show that the proposed method consistently outperforms traditional parallel imaging methods and existing UNNs, and even outperforms the state-of-the-art supervised-trained k-space deep learning methods in some cases.

A Pre-Computing Solution for Online Advertising Serving

Click-Through Rate (CTR) prediction plays a key role in online advertising systems and online advertising. Constrained by strict requirements on online inference efficiency, it is often difficult to deploy useful but computationally intensive modules such as long-term behaviors modeling. Most recent works attempt to mitigate the online calculation issue of long historical behaviors by adopting two-stage methods to balance online efficiency and effectiveness. However, the information gaps caused by two-stage modeling may result in a diminished performance gain. In this work, we propose a novel framework called PCM to address this challenge in the view of system deployment. By deploying a pre-computing sub-module parallel to the retrieval stage, our PCM effectively reduces overall inference time which enables complex modeling in the ranking stage. Comprehensive offline and online experiments are conducted on the long-term user behaviors module to validate the effectiveness of our solution for the complex models. Moreover, our framework has been deployed into a large-scale real-world E-commerce system serving the main interface of hundreds of millions of active users, by deploying long sequential user behavior model in PCM. We achieved a 3\% CTR gain, with almost no increase in the ranking latency, compared to the base framework demonstrated from the online A/B test. To our knowledge, we are the first to propose an end-to-end solution for online training and deployment on complex CTR models from the system framework side.

Research: A Pre-Computing Solution for Online Advertising Serving

Click-Through Rate (CTR) prediction plays a key role in online advertising systems and online advertising. Constrained by strict requirements on online inference efficiency, it is often difficult to deploy useful but computationally intensive modules such as long-term behaviors modeling. Most recent works attempt to mitigate the online calculation issue of long historical behaviors by adopting two-stage methods to balance online efficiency and effectiveness. However, the information gaps caused by two-stage modeling may result in a diminished performance gain. In this work, we propose a novel framework called PCM to address this challenge in the view of system deployment. By deploying a pre-computing sub-module parallel to the retrieval stage, our PCM effectively reduces overall inference time which enables complex modeling in the ranking stage. Comprehensive offline and online experiments are conducted on the long-term user behaviors module to validate the effectiveness of our solution for the complex models. Moreover, our framework has been deployed into a large-scale real-world E-commerce system serving the main interface of hundreds of millions of active users, by deploying long sequential user behavior model in PCM. We achieved a 3\% CTR gain, with almost no increase in the ranking latency, compared to the base framework demonstrated from the online A/B test. To our knowledge, we are the first to propose an end-to-end solution for online training and deployment on complex CTR models from the system framework side.

Rethinking Position Bias Modeling with Knowledge Distillation for CTR Prediction

Click-through rate (CTR) Prediction is of great importance in real-world online ads systems. One challenge for the CTR prediction task is to capture the real interest of users from their clicked items, which is inherently biased by presented positions of items, i.e., more front positions tend to obtain higher CTR values. A popular line of existing works focuses on explicitly estimating position bias by result randomization which is expensive and inefficient, or by inverse propensity weighting (IPW) which relies heavily on the quality of the propensity estimation. Another common solution is modeling position as features during offline training and simply adopting fixed value or dropout tricks when serving. However, training-inference inconsistency can lead to sub-optimal performance. Furthermore, post-click information such as position values is informative while less exploited in CTR prediction. This work proposes a simple yet efficient knowledge distillation framework to alleviate the impact of position bias and leverage position information to improve CTR prediction. We demonstrate the performance of our proposed method on a real-world production dataset and online A/B tests, achieving significant improvements over competing baseline models. The proposed method has been deployed in the real world online ads systems, serving main traffic on one of the world's largest e-commercial platforms.