Unlabeled Cross-Center Automatic Analysis for TAAD: An Integrated Framework from Segmentation to Clinical Features

Type A Aortic Dissection (TAAD) is a life-threatening cardiovascular emergency that demands rapid and precise preoperative evaluation. While key anatomical and pathological features are decisive for surgical planning, current research focuses predominantly on improving segmentation accuracy, leaving the reliable, quantitative extraction of clinically actionable features largely under-explored. Furthermore, constructing comprehensive TAAD datasets requires labor-intensive, expert level pixel-wise annotations, which is impractical for most clinical institutions. Due to significant domain shift, models trained on a single center dataset also suffer from severe performance degradation during cross-institutional deployment. This study addresses a clinically critical challenge: the accurate extraction of key TAAD clinical features during cross-institutional deployment in the total absence of target-domain annotations. To this end, we propose an unsupervised domain adaptation (UDA)-driven framework for the automated extraction of TAAD clinical features. The framework leverages limited source-domain labels while effectively adapting to unlabeled data from target domains. Tailored for real-world emergency workflows, our framework aims to achieve stable cross-institutional multi-class segmentation, reliable and quantifiable clinical feature extraction, and practical deployability independent of high-cost annotations. Extensive experiments demonstrate that our method significantly improves cross-domain segmentation performance compared to existing state-of-the-art approaches. More importantly, a reader study involving multiple cardiovascular surgeons confirms that the automatically extracted clinical features provide meaningful assistance for preoperative assessment, highlighting the practical utility of the proposed end-to-end segmentation-to-feature pipeline.

MemoryCD: Benchmarking Long-Context User Memory of LLM Agents for Lifelong Cross-Domain Personalization

Recent advancements in Large Language Models (LLMs) have expanded context windows to million-token scales, yet benchmarks for evaluating memory remain limited to short-session synthetic dialogues. We introduce \textsc{MemoryCD}, the first large-scale, user-centric, cross-domain memory benchmark derived from lifelong real-world behaviors in the Amazon Review dataset. Unlike existing memory datasets that rely on scripted personas to generate synthetic user data, \textsc{MemoryCD} tracks authentic user interactions across years and multiple domains. We construct a multi-faceted long-context memory evaluation pipeline of 14 state-of-the-art LLM base models with 6 memory method baselines on 4 distinct personalization tasks over 12 diverse domains to evaluate an agent's ability to simulate real user behaviors in both single and cross-domain settings. Our analysis reveals that existing memory methods are far from user satisfaction in various domains, offering the first testbed for cross-domain life-long personalization evaluation.

An Experimental Comparison of the Most Popular Approaches to Fake News Detection

In recent years, fake news detection has received increasing attention in public debate and scientific research. Despite advances in detection techniques, the production and spread of false information have become more sophisticated, driven by Large Language Models (LLMs) and the amplification power of social media. We present a critical assessment of 12 representative fake news detection approaches, spanning traditional machine learning, deep learning, transformers, and specialized cross-domain architectures. We evaluate these methods on 10 publicly available datasets differing in genre, source, topic, and labeling rationale. We address text-only English fake news detection as a binary classification task by harmonizing labels into "Real" and "Fake" to ensure a consistent evaluation protocol. We acknowledge that label semantics vary across datasets and that harmonization inevitably removes such semantic nuances. Each dataset is treated as a distinct domain. We conduct in-domain, multi-domain and cross-domain experiments to simulate real-world scenarios involving domain shift and out-of-distribution data. Fine-tuned models perform well in-domain but struggle to generalize. Cross-domain architectures can reduce this gap but are data-hungry, while LLMs offer a promising alternative through zero- and few-shot learning. Given inherent dataset confounds and possible pre-training exposure, results should be interpreted as robustness evaluations within this English, text-only protocol.

SlotVTG: Object-Centric Adapter for Generalizable Video Temporal Grounding

Multimodal Large Language Models (MLLMs) have shown strong performance on Video Temporal Grounding (VTG). However, their coarse recognition capabilities are insufficient for fine-grained temporal understanding, making task-specific fine-tuning indispensable. This fine-tuning causes models to memorize dataset-specific shortcuts rather than faithfully grounding in the actual visual content, leading to poor Out-of-Domain (OOD) generalization. Object-centric learning offers a promising remedy by decomposing scenes into entity-level representations, but existing approaches require re-running the entire multi-stage training pipeline from scratch. We propose SlotVTG, a framework that steers MLLMs toward object-centric, input-grounded visual reasoning at minimal cost. SlotVTG introduces a lightweight slot adapter that decomposes visual tokens into abstract slots via slot attention and reconstructs the original sequence, where objectness priors from a self-supervised vision model encourage semantically coherent slot formation. Cross-domain evaluation on standard VTG benchmarks demonstrates that our approach significantly improves OOD robustness while maintaining competitive In-Domain (ID) performance with minimal overhead.

OptiSAR-Net++: A Large-Scale Benchmark and Transformer-Free Framework for Cross-Domain Remote Sensing Visual Grounding

Remote sensing visual grounding (RSVG) aims to localize specific targets in remote sensing images using natural language expressions. However, existing methods are restricted to single-sensor domains, i.e., either optical or synthetic aperture radar (SAR), limiting their real-world applicability. In this paper, we introduce the Cross-Domain RSVG (CD-RSVG) task and construct OptSAR-RSVG, the first large-scale benchmark dataset for this setting. To tackle the challenges of cross-domain feature modeling, computational inefficiency, and fine-grained semantic discrimination, we propose OptiSAR-Net++. Our framework features a patch-level Low-Rank Adaptation Mixture of Experts (PL-MoE) for efficient cross-domain feature decoupling. To mitigate the substantial computational overhead of Transformer decoding frameworks, we adopt a CLIP-based contrastive paradigm and further incorporate dynamic adversarial negative sampling, thereby transforming generative regression into an efficient cross-modal matching process. Additionally, a text-guided dual-gate fusion module (TGDF-SSA) and a region-aware auxiliary head are introduced to enhance semantic-visual alignment and spatial modeling. Extensive experiments demonstrate that OptiSAR-Net++ achieves SOTA performance on both OptSAR-RSVG and DIOR-RSVG benchmarks, offering significant advantages in localization accuracy and efficiency. Our code and dataset will be made publicly available.

CIV-DG: Conditional Instrumental Variables for Domain Generalization in Medical Imaging

Cross-site generalizability in medical AI is fundamentally compromised by selection bias, a structural mechanism where patient demographics (e.g., age, severity) non-randomly dictate hospital assignment. Conventional Domain Generalization (DG) paradigms, which predominantly target image-level distribution shifts, fail to address the resulting spurious correlations between site-specific variations and diagnostic labels. To surmount this identifiability barrier, we propose CIV-DG, a causal framework that leverages Conditional Instrumental Variables to disentangle pathological semantics from scanner-induced artifacts. By relaxing the strict random assignment assumption of standard IV methods, CIV-DG accommodates complex clinical scenarios where hospital selection is endogenously driven by patient demographics. We instantiate this theory via a Deep Generalized Method of Moments (DeepGMM) architecture, employing a conditional critic to minimize moment violations and enforce instrument-error orthogonality within demographic strata. Extensive experiments on the Camelyon17 benchmark and large-scale Chest X-Ray datasets demonstrate that CIV-DG significantly outperforms leading baselines, validating the efficacy of conditional causal mechanisms in resolving structural confounding for robust medical AI.

Enhanced Mycelium of Thought (EMoT): A Bio-Inspired Hierarchical Reasoning Architecture with Strategic Dormancy and Mnemonic Encoding

Current prompting paradigms for large language models (LLMs), including Chain-of-Thought (CoT) and Tree-of-Thoughts (ToT), follow linear or tree-structured reasoning paths that lack persistent memory, strategic dormancy, and cross-domain synthesis. We present the Enhanced Mycelium of Thought (EMoT) framework, a bio-inspired reasoning architecture that organises cognitive processing into a four-level hierarchy (Micro, Meso, Macro, Meta), implements strategic dormancy and reactivation of reasoning nodes, and integrates a Memory Palace with five mnemonic encoding styles. EMoT is a research prototype for complex, multi-domain problems, not a general-purpose prompting enhancement. Two complementary evaluations reveal a characteristic trade-off. In a blind LLM-as-Judge evaluation across three domains, EMoT achieved near-parity with CoT (4.20 vs. 4.33/5.0) with higher stability, and outperformed CoT on Cross-Domain Synthesis (4.8 vs. 4.4). Ablation studies show that strategic dormancy is architecturally essential (quality collapsed from 4.2 to 1.0 when disabled). On a 15-item short-answer benchmark, EMoT (27%) substantially underperformed simpler baselines, confirming systematic overthinking on simple problems. These results are subject to important limitations: small sample sizes (n=3 complex cases, n=15 short-answer items), LLM-as-Judge evaluation with potential self-preference bias, and approximately 33-fold computational cost overhead. To our knowledge, EMoT is the first reasoning framework to combine hierarchical topology, strategic thought dormancy with reactivation, and mnemonic memory encoding in a single architecture.

SAVe: Self-Supervised Audio-visual Deepfake Detection Exploiting Visual Artifacts and Audio-visual Misalignment

Multimodal deepfakes can exhibit subtle visual artifacts and cross-modal inconsistencies, which remain challenging to detect, especially when detectors are trained primarily on curated synthetic forgeries. Such synthetic dependence can introduce dataset and generator bias, limiting scalability and robustness to unseen manipulations. We propose SAVe, a self-supervised audio-visual deepfake detection framework that learns entirely on authentic videos. SAVe generates on-the-fly, identity-preserving, region-aware self-blended pseudo-manipulations to emulate tampering artifacts, enabling the model to learn complementary visual cues across multiple facial granularities. To capture cross-modal evidence, SAVe also models lip-speech synchronization via an audio-visual alignment component that detects temporal misalignment patterns characteristic of audio-visual forgeries. Experiments on FakeAVCeleb and AV-LipSync-TIMIT demonstrate competitive in-domain performance and strong cross-dataset generalization, highlighting self-supervised learning as a scalable paradigm for multimodal deepfake detection.

SHANDS: A Multi-View Dataset and Benchmark for Surgical Hand-Gesture and Error Recognition Toward Medical Training

In surgical training for medical students, proficiency development relies on expert-led skill assessment, which is costly, time-limited, difficult to scale, and its expertise remains confined to institutions with available specialists. Automated AI-based assessment offers a viable alternative, but progress is constrained by the lack of datasets containing realistic trainee errors and the multi-view variability needed to train robust computer vision approaches. To address this gap, we present Surgical-Hands (SHands), a large-scale multi-view video dataset for surgical hand-gesture and error recognition for medical training. \textsc{SHands} captures linear incision and suturing using five RGB cameras from complementary viewpoints, performed by 52 participants (20 experts and 32 trainees), each completing three standardized trials per procedure. The videos are annotated at the frame level with 15 gesture primitives and include a validated taxonomy of 8 trainee error types, enabling both gesture recognition and error detection. We further define standardized evaluation protocols for single-view, multi-view, and cross-view generalization, and benchmark state-of-the-art deep learning models on the dataset. SHands is publicly released to support the development of robust and scalable AI systems for surgical training grounded in clinically curated domain knowledge.

Synthetic Cardiac MRI Image Generation using Deep Generative Models

Synthetic cardiac MRI (CMRI) generation has emerged as a promising strategy to overcome the scarcity of annotated medical imaging data. Recent advances in GANs, VAEs, diffusion probabilistic models, and flow-matching techniques aim to generate anatomically accurate images while addressing challenges such as limited labeled datasets, vendor variability, and risks of privacy leakage through model memorization. Maskconditioned generation improves structural fidelity by guiding synthesis with segmentation maps, while diffusion and flowmatching models offer strong boundary preservation and efficient deterministic transformations. Cross-domain generalization is further supported through vendor-style conditioning and preprocessing steps like intensity normalization. To ensure privacy, studies increasingly incorporate membership inference attacks, nearest-neighbor analyses, and differential privacy mechanisms. Utility evaluations commonly measure downstream segmentation performance, with evidence showing that anatomically constrained synthetic data can enhance accuracy and robustness across multi-vendor settings. This review aims to compare existing CMRI generation approaches through the lenses of fidelity, utility, and privacy, highlighting current limitations and the need for integrated, evaluation-driven frameworks for reliable clinical workflows.