Organ-Agents: Virtual Human Physiology Simulator via LLMs

Recent advances in large language models (LLMs) have enabled new possibilities in simulating complex physiological systems. We introduce Organ-Agents, a multi-agent framework that simulates human physiology via LLM-driven agents. Each Simulator models a specific system (e.g., cardiovascular, renal, immune). Training consists of supervised fine-tuning on system-specific time-series data, followed by reinforcement-guided coordination using dynamic reference selection and error correction. We curated data from 7,134 sepsis patients and 7,895 controls, generating high-resolution trajectories across 9 systems and 125 variables. Organ-Agents achieved high simulation accuracy on 4,509 held-out patients, with per-system MSEs <0.16 and robustness across SOFA-based severity strata. External validation on 22,689 ICU patients from two hospitals showed moderate degradation under distribution shifts with stable simulation. Organ-Agents faithfully reproduces critical multi-system events (e.g., hypotension, hyperlactatemia, hypoxemia) with coherent timing and phase progression. Evaluation by 15 critical care physicians confirmed realism and physiological plausibility (mean Likert ratings 3.9 and 3.7). Organ-Agents also enables counterfactual simulations under alternative sepsis treatment strategies, generating trajectories and APACHE II scores aligned with matched real-world patients. In downstream early warning tasks, classifiers trained on synthetic data showed minimal AUROC drops (<0.04), indicating preserved decision-relevant patterns. These results position Organ-Agents as a credible, interpretable, and generalizable digital twin for precision diagnosis, treatment simulation, and hypothesis testing in critical care.

BRepFormer: Transformer-Based B-rep Geometric Feature Recognition

Recognizing geometric features on B-rep models is a cornerstone technique for multimedia content-based retrieval and has been widely applied in intelligent manufacturing. However, previous research often merely focused on Machining Feature Recognition (MFR), falling short in effectively capturing the intricate topological and geometric characteristics of complex geometry features. In this paper, we propose BRepFormer, a novel transformer-based model to recognize both machining feature and complex CAD models' features. BRepFormer encodes and fuses the geometric and topological features of the models. Afterwards, BRepFormer utilizes a transformer architecture for feature propagation and a recognition head to identify geometry features. During each iteration of the transformer, we incorporate a bias that combines edge features and topology features to reinforce geometric constraints on each face. In addition, we also proposed a dataset named Complex B-rep Feature Dataset (CBF), comprising 20,000 B-rep models. By covering more complex B-rep models, it is better aligned with industrial applications. The experimental results demonstrate that BRepFormer achieves state-of-the-art accuracy on the MFInstSeg, MFTRCAD, and our CBF datasets.

DragScene: Interactive 3D Scene Editing with Single-view Drag Instructions

3D editing has shown remarkable capability in editing scenes based on various instructions. However, existing methods struggle with achieving intuitive, localized editing, such as selectively making flowers blossom. Drag-style editing has shown exceptional capability to edit images with direct manipulation instead of ambiguous text commands. Nevertheless, extending drag-based editing to 3D scenes presents substantial challenges due to multi-view inconsistency. To this end, we introduce DragScene, a framework that integrates drag-style editing with diverse 3D representations. First, latent optimization is performed on a reference view to generate 2D edits based on user instructions. Subsequently, coarse 3D clues are reconstructed from the reference view using a point-based representation to capture the geometric details of the edits. The latent representation of the edited view is then mapped to these 3D clues, guiding the latent optimization of other views. This process ensures that edits are propagated seamlessly across multiple views, maintaining multi-view consistency. Finally, the target 3D scene is reconstructed from the edited multi-view images. Extensive experiments demonstrate that DragScene facilitates precise and flexible drag-style editing of 3D scenes, supporting broad applicability across diverse 3D representations.

SizeGS: Size-aware Compression of 3D Gaussians with Hierarchical Mixed Precision Quantization

Effective compression technology is crucial for 3DGS to adapt to varying storage and transmission conditions. However, existing methods fail to address size constraints while maintaining optimal quality. In this paper, we introduce SizeGS, a framework that compresses 3DGS within a specified size budget while optimizing visual quality. We start with a size estimator to establish a clear relationship between file size and hyperparameters. Leveraging this estimator, we incorporate mixed precision quantization (MPQ) into 3DGS attributes, structuring MPQ in two hierarchical level -- inter-attribute and intra-attribute -- to optimize visual quality under the size constraint. At the inter-attribute level, we assign bit-widths to each attribute channel by formulating the combinatorial optimization as a 0-1 integer linear program, which can be efficiently solved. At the intra-attribute level, we divide each attribute channel into blocks of vectors, quantizing each vector based on the optimal bit-width derived at the inter-attribute level. Dynamic programming determines block lengths. Using the size estimator and MPQ, we develop a calibrated algorithm to identify optimal hyperparameters in just 10 minutes, achieving a 1.69$\times$ efficiency increase with quality comparable to state-of-the-art methods.

FiffDepth: Feed-forward Transformation of Diffusion-Based Generators for Detailed Depth Estimation

Monocular Depth Estimation (MDE) is essential for applications like 3D scene reconstruction, autonomous navigation, and AI content creation. However, robust MDE remains challenging due to noisy real-world data and distribution gaps in synthetic datasets. Existing methods often struggle with low efficiency, reduced accuracy, and lack of detail. To address this, we propose an efficient approach for leveraging diffusion priors and introduce FiffDepth, a framework that transforms diffusion-based image generators into a feedforward architecture for detailed depth estimation. By preserving key generative features and integrating the strong generalization capabilities of models like dinov2, FiffDepth achieves enhanced accuracy, stability, and fine-grained detail, offering a significant improvement in MDE performance across diverse real-world scenarios.

MesonGS: Post-training Compression of 3D Gaussians via Efficient Attribute Transformation

3D Gaussian Splatting demonstrates excellent quality and speed in novel view synthesis. Nevertheless, the huge file size of the 3D Gaussians presents challenges for transmission and storage. Current works design compact models to replace the substantial volume and attributes of 3D Gaussians, along with intensive training to distill information. These endeavors demand considerable training time, presenting formidable hurdles for practical deployment. To this end, we propose MesonGS, a codec for post-training compression of 3D Gaussians. Initially, we introduce a measurement criterion that considers both view-dependent and view-independent factors to assess the impact of each Gaussian point on the rendering output, enabling the removal of insignificant points. Subsequently, we decrease the entropy of attributes through two transformations that complement subsequent entropy coding techniques to enhance the file compression rate. More specifically, we first replace rotation quaternions with Euler angles; then, we apply region adaptive hierarchical transform to key attributes to reduce entropy. Lastly, we adopt finer-grained quantization to avoid excessive information loss. Moreover, a well-crafted finetune scheme is devised to restore quality. Extensive experiments demonstrate that MesonGS significantly reduces the size of 3D Gaussians while preserving competitive quality.

Tuning-Free Visual Customization via View Iterative Self-Attention Control

Fine-Tuning Diffusion Models enable a wide range of personalized generation and editing applications on diverse visual modalities. While Low-Rank Adaptation (LoRA) accelerates the fine-tuning process, it still requires multiple reference images and time-consuming training, which constrains its scalability for large-scale and real-time applications. In this paper, we propose \textit{View Iterative Self-Attention Control (VisCtrl)} to tackle this challenge. Specifically, VisCtrl is a training-free method that injects the appearance and structure of a user-specified subject into another subject in the target image, unlike previous approaches that require fine-tuning the model. Initially, we obtain the initial noise for both the reference and target images through DDIM inversion. Then, during the denoising phase, features from the reference image are injected into the target image via the self-attention mechanism. Notably, by iteratively performing this feature injection process, we ensure that the reference image features are gradually integrated into the target image. This approach results in consistent and harmonious editing with only one reference image in a few denoising steps. Moreover, benefiting from our plug-and-play architecture design and the proposed Feature Gradual Sampling strategy for multi-view editing, our method can be easily extended to edit in complex visual domains. Extensive experiments show the efficacy of VisCtrl across a spectrum of tasks, including personalized editing of images, videos, and 3D scenes.

NOFA: NeRF-based One-shot Facial Avatar Reconstruction

3D facial avatar reconstruction has been a significant research topic in computer graphics and computer vision, where photo-realistic rendering and flexible controls over poses and expressions are necessary for many related applications. Recently, its performance has been greatly improved with the development of neural radiance fields (NeRF). However, most existing NeRF-based facial avatars focus on subject-specific reconstruction and reenactment, requiring multi-shot images containing different views of the specific subject for training, and the learned model cannot generalize to new identities, limiting its further applications. In this work, we propose a one-shot 3D facial avatar reconstruction framework that only requires a single source image to reconstruct a high-fidelity 3D facial avatar. For the challenges of lacking generalization ability and missing multi-view information, we leverage the generative prior of 3D GAN and develop an efficient encoder-decoder network to reconstruct the canonical neural volume of the source image, and further propose a compensation network to complement facial details. To enable fine-grained control over facial dynamics, we propose a deformation field to warp the canonical volume into driven expressions. Through extensive experimental comparisons, we achieve superior synthesis results compared to several state-of-the-art methods.

DreamDiffusion: Generating High-Quality Images from Brain EEG Signals

This paper introduces DreamDiffusion, a novel method for generating high-quality images directly from brain electroencephalogram (EEG) signals, without the need to translate thoughts into text. DreamDiffusion leverages pre-trained text-to-image models and employs temporal masked signal modeling to pre-train the EEG encoder for effective and robust EEG representations. Additionally, the method further leverages the CLIP image encoder to provide extra supervision to better align EEG, text, and image embeddings with limited EEG-image pairs. Overall, the proposed method overcomes the challenges of using EEG signals for image generation, such as noise, limited information, and individual differences, and achieves promising results. Quantitative and qualitative results demonstrate the effectiveness of the proposed method as a significant step towards portable and low-cost ``thoughts-to-image'', with potential applications in neuroscience and computer vision. The code is available here \url{https://github.com/bbaaii/DreamDiffusion}.

Temporal-spatial Correlation Attention Network for Clinical Data Analysis in Intensive Care Unit

In recent years, medical information technology has made it possible for electronic health record (EHR) to store fairly complete clinical data. This has brought health care into the era of "big data". However, medical data are often sparse and strongly correlated, which means that medical problems cannot be solved effectively. With the rapid development of deep learning in recent years, it has provided opportunities for the use of big data in healthcare. In this paper, we propose a temporal-saptial correlation attention network (TSCAN) to handle some clinical characteristic prediction problems, such as predicting death, predicting length of stay, detecting physiologic decline, and classifying phenotypes. Based on the design of the attention mechanism model, our approach can effectively remove irrelevant items in clinical data and irrelevant nodes in time according to different tasks, so as to obtain more accurate prediction results. Our method can also find key clinical indicators of important outcomes that can be used to improve treatment options. Our experiments use information from the Medical Information Mart for Intensive Care (MIMIC-IV) database, which is open to the public. Finally, we have achieved significant performance benefits of 2.0\% (metric) compared to other SOTA prediction methods. We achieved a staggering 90.7\% on mortality rate, 45.1\% on length of stay. The source code can be find: \url{https://github.com/yuyuheintju/TSCAN}.