Weakly Supervised Spatial Implicit Neural Representation Learning for 3D MRI-Ultrasound Deformable Image Registration in HDR Prostate Brachytherapy

Purpose: Accurate 3D MRI-ultrasound (US) deformable registration is critical for real-time guidance in high-dose-rate (HDR) prostate brachytherapy. We present a weakly supervised spatial implicit neural representation (SINR) method to address modality differences and pelvic anatomy challenges. Methods: The framework uses sparse surface supervision from MRI/US segmentations instead of dense intensity matching. SINR models deformations as continuous spatial functions, with patient-specific surface priors guiding a stationary velocity field for biologically plausible deformations. Validation included 20 public Prostate-MRI-US-Biopsy cases and 10 institutional HDR cases, evaluated via Dice similarity coefficient (DSC), mean surface distance (MSD), and 95% Hausdorff distance (HD95). Results: The proposed method achieved robust registration. For the public dataset, prostate DSC was $0.93 \pm 0.05$, MSD $0.87 \pm 0.10$ mm, and HD95 $1.58 \pm 0.37$ mm. For the institutional dataset, prostate CTV achieved DSC $0.88 \pm 0.09$, MSD $1.21 \pm 0.38$ mm, and HD95 $2.09 \pm 1.48$ mm. Bladder and rectum performance was lower due to ultrasound's limited field of view. Visual assessments confirmed accurate alignment with minimal discrepancies. Conclusion: This study introduces a novel weakly supervised SINR-based approach for 3D MRI-US deformable registration. By leveraging sparse surface supervision and spatial priors, it achieves accurate, robust, and computationally efficient registration, enhancing real-time image guidance in HDR prostate brachytherapy and improving treatment precision.

ZiGong 1.0: A Large Language Model for Financial Credit

Large Language Models (LLMs) have demonstrated strong performance across various general Natural Language Processing (NLP) tasks. However, their effectiveness in financial credit assessment applications remains suboptimal, primarily due to the specialized financial expertise required for these tasks. To address this limitation, we propose ZiGong, a Mistral-based model enhanced through multi-task supervised fine-tuning. To specifically combat model hallucination in financial contexts, we introduce a novel data pruning methodology. Our approach utilizes a proxy model to score training samples, subsequently combining filtered data with original datasets for model training. This data refinement strategy effectively reduces hallucinations in LLMs while maintaining reliability in downstream financial applications. Experimental results show our method significantly enhances model robustness and prediction accuracy in real-world financial scenarios.

Correcting Large Language Model Behavior via Influence Function

Recent advancements in AI alignment techniques have significantly improved the alignment of large language models (LLMs) with static human preferences. However, the dynamic nature of human preferences can render some prior training data outdated or even erroneous, ultimately causing LLMs to deviate from contemporary human preferences and societal norms. Existing methodologies, whether they involve the curation of new data for continual alignment or the manual correction of outdated data for re-alignment, demand costly human resources. To address this challenge, we propose a novel approach, Large Language Model Behavior Correction with Influence Function Recall and Post-Training (LANCET), which requires no human involvement. LANCET consists of two phases: (1) using influence functions to identify the training data that significantly impact undesirable model outputs, and (2) applying an Influence function-driven Bregman Optimization (IBO) technique to adjust the model's behavior based on these influence distributions. Our experiments demonstrate that LANCET effectively and efficiently correct inappropriate behaviors of LLMs. Furthermore, LANCET can outperform methods that rely on collecting human preferences, and it enhances the interpretability of learning human preferences within LLMs.

Precision-Enhanced Human-Object Contact Detection via Depth-Aware Perspective Interaction and Object Texture Restoration

Human-object contact (HOT) is designed to accurately identify the areas where humans and objects come into contact. Current methods frequently fail to account for scenarios where objects are frequently blocking the view, resulting in inaccurate identification of contact areas. To tackle this problem, we suggest using a perspective interaction HOT detector called PIHOT, which utilizes a depth map generation model to offer depth information of humans and objects related to the camera, thereby preventing false interaction detection. Furthermore, we use mask dilatation and object restoration techniques to restore the texture details in covered areas, improve the boundaries between objects, and enhance the perception of humans interacting with objects. Moreover, a spatial awareness perception is intended to concentrate on the characteristic features close to the points of contact. The experimental results show that the PIHOT algorithm achieves state-of-the-art performance on three benchmark datasets for HOT detection tasks. Compared to the most recent DHOT, our method enjoys an average improvement of 13%, 27.5%, 16%, and 18.5% on SC-Acc., C-Acc., mIoU, and wIoU metrics, respectively.

A Heterogeneous Graph Neural Network Fusing Functional and Structural Connectivity for MCI Diagnosis

Brain connectivity alternations associated with brain disorders have been widely reported in resting-state functional imaging (rs-fMRI) and diffusion tensor imaging (DTI). While many dual-modal fusion methods based on graph neural networks (GNNs) have been proposed, they generally follow homogenous fusion ways ignoring rich heterogeneity of dual-modal information. To address this issue, we propose a novel method that integrates functional and structural connectivity based on heterogeneous graph neural networks (HGNNs) to better leverage the rich heterogeneity in dual-modal images. We firstly use blood oxygen level dependency and whiter matter structure information provided by rs-fMRI and DTI to establish homo-meta-path, capturing node relationships within the same modality. At the same time, we propose to establish hetero-meta-path based on structure-function coupling and brain community searching to capture relations among cross-modal nodes. Secondly, we further introduce a heterogeneous graph pooling strategy that automatically balances homo- and hetero-meta-path, effectively leveraging heterogeneous information and preventing feature confusion after pooling. Thirdly, based on the flexibility of heterogeneous graphs, we propose a heterogeneous graph data augmentation approach that can conveniently address the sample imbalance issue commonly seen in clinical diagnosis. We evaluate our method on ADNI-3 dataset for mild cognitive impairment (MCI) diagnosis. Experimental results indicate the proposed method is effective and superior to other algorithms, with a mean classification accuracy of 93.3%.

FairMindSim: Alignment of Behavior, Emotion, and Belief in Humans and LLM Agents Amid Ethical Dilemmas

AI alignment is a pivotal issue concerning AI control and safety. It should consider not only value-neutral human preferences but also moral and ethical considerations. In this study, we introduced FairMindSim, which simulates the moral dilemma through a series of unfair scenarios. We used LLM agents to simulate human behavior, ensuring alignment across various stages. To explore the various socioeconomic motivations, which we refer to as beliefs, that drive both humans and LLM agents as bystanders to intervene in unjust situations involving others, and how these beliefs interact to influence individual behavior, we incorporated knowledge from relevant sociological fields and proposed the Belief-Reward Alignment Behavior Evolution Model (BREM) based on the recursive reward model (RRM). Our findings indicate that, behaviorally, GPT-4o exhibits a stronger sense of social justice, while humans display a richer range of emotions. Additionally, we discussed the potential impact of emotions on behavior. This study provides a theoretical foundation for applications in aligning LLMs with altruistic values.

A Review of Human-Object Interaction Detection

Human-object interaction (HOI) detection plays a key role in high-level visual understanding, facilitating a deep comprehension of human activities. Specifically, HOI detection aims to locate the humans and objects involved in interactions within images or videos and classify the specific interactions between them. The success of this task is influenced by several key factors, including the accurate localization of human and object instances, as well as the correct classification of object categories and interaction relationships. This paper systematically summarizes and discusses the recent work in image-based HOI detection. First, the mainstream datasets involved in HOI relationship detection are introduced. Furthermore, starting with two-stage methods and end-to-end one-stage detection approaches, this paper comprehensively discusses the current developments in image-based HOI detection, analyzing the strengths and weaknesses of these two methods. Additionally, the advancements of zero-shot learning, weakly supervised learning, and the application of large-scale language models in HOI detection are discussed. Finally, the current challenges in HOI detection are outlined, and potential research directions and future trends are explored.

PCLMix: Weakly Supervised Medical Image Segmentation via Pixel-Level Contrastive Learning and Dynamic Mix Augmentation

In weakly supervised medical image segmentation, the absence of structural priors and the discreteness of class feature distribution present a challenge, i.e., how to accurately propagate supervision signals from local to global regions without excessively spreading them to other irrelevant regions? To address this, we propose a novel weakly supervised medical image segmentation framework named PCLMix, comprising dynamic mix augmentation, pixel-level contrastive learning, and consistency regularization strategies. Specifically, PCLMix is built upon a heterogeneous dual-decoder backbone, addressing the absence of structural priors through a strategy of dynamic mix augmentation during training. To handle the discrete distribution of class features, PCLMix incorporates pixel-level contrastive learning based on prediction uncertainty, effectively enhancing the model's ability to differentiate inter-class pixel differences and intra-class consistency. Furthermore, to reinforce segmentation consistency and robustness, PCLMix employs an auxiliary decoder for dual consistency regularization. In the inference phase, the auxiliary decoder will be dropped and no computation complexity is increased. Extensive experiments on the ACDC dataset demonstrate that PCLMix appropriately propagates local supervision signals to the global scale, further narrowing the gap between weakly supervised and fully supervised segmentation methods. Our code is available at https://github.com/Torpedo2648/PCLMix.

FinLangNet: A Novel Deep Learning Framework for Credit Risk Prediction Using Linguistic Analogy in Financial Data

Recent industrial applications in risk prediction still heavily rely on extensively manually-tuned, statistical learning methods. Real-world financial data, characterized by its high-dimensionality, sparsity, high noise levels, and significant imbalance, poses unique challenges for the effective application of deep neural network models. In this work, we introduce a novel deep learning risk prediction framework, FinLangNet, which conceptualizes credit loan trajectories in a structure that mirrors linguistic constructs. This framework is tailored for credit risk prediction using real-world financial data, drawing on structural similarities to language by adapting natural language processing techniques. It focuses on analyzing the evolution and predictability of credit histories through detailed financial event sequences. Our research demonstrates that FinLangNet surpasses traditional statistical methods in predicting credit risk and that its integration with these methods enhances credit card fraud prediction models, achieving a significant improvement of over 1.5 points in the Kolmogorov-Smirnov metric.

Knowledge-Aware Multi-Intent Contrastive Learning for Multi-Behavior Recommendation

Multi-behavioral recommendation optimizes user experiences by providing users with more accurate choices based on their diverse behaviors, such as view, add to cart, and purchase. Current studies on multi-behavioral recommendation mainly explore the connections and differences between multi-behaviors from an implicit perspective. Specifically, they directly model those relations using black-box neural networks. In fact, users' interactions with items under different behaviors are driven by distinct intents. For instance, when users view products, they tend to pay greater attention to information such as ratings and brands. However, when it comes to the purchasing phase, users become more price-conscious. To tackle this challenge and data sparsity problem in the multi-behavioral recommendation, we propose a novel model: Knowledge-Aware Multi-Intent Contrastive Learning (KAMCL) model. This model uses relationships in the knowledge graph to construct intents, aiming to mine the connections between users' multi-behaviors from the perspective of intents to achieve more accurate recommendations. KAMCL is equipped with two contrastive learning schemes to alleviate the data scarcity problem and further enhance user representations. Extensive experiments on three real datasets demonstrate the superiority of our model.